Recently added articles from Bioscience Technology:
Detecting of circulating epithelial cells: what if a physician could just look to see if there were any CTCs in a patient's blood?(Cover story)
Jul 01, 2008; May, Mike ... [ILLUSTRATION OMITTED] Tumor cells escape. In fact, scientists learned long ago--as early as 1869--that cancer cells can end up in the blood. By the mid-1950s, some researchers thought that these so-called circulating tumor cells (CTCs) might help clinicians catch cancer earlier ...
The New Yorker: Barack Obama cover.(Editor's Note)
Jul 01, 2008; Ernst, Steve ... By the time you read this, the controversy over The New Yorker magazine cover depicting Michelle and Barack Obama as flag-burning terrorists will be about three weeks behind us. (The story literally broke as I was about to do this column, so please, indulge me.) I doubt the debate about ...
Single Molecule Sequencing without amplification.(Editor's Choice)
Jul 01, 2008 ... [ILLUSTRATION OMITTED] True Single Molecule Sequencing approach to genomic analysis directly measures single DNA molecules, without amplification. The technology accurately interrogates billions of single strands of DNA (or RNA) in parallel by detecting single nucleotide ...
Multi-dimensional image analysis.(Editor's Choice)
Jul 01, 2008 ... Multi-dimensional image analysis platform Definiens XD extracts previously unattainable levels of volumetric and morphological intelligence from digital data. The results provide a deep understanding of the subtle biological changes associated with disease progression and treatment, and ...
Cancer antibodies (BAGE-1, GnTV).(Editor's Choice)
Jul 01, 2008 ... [ILLUSTRATION OMITTED] BAGE-1 also known as B melanoma antigen, 1s a secreted protein expressed in 22% of melanomas. 30% of infiltrating bladder carcinomas. 10% of mammary carcinomas. 8% of head and neck squamous cell carcinomas, and 6% of non-cell lung carcinomas. It is silent ...
64 channel pipette.(Editor's Choice)
Jul 01, 2008 ... [ILLUSTRATION OMITTED] The CappAero 64 64-channel pipette simultaneously pipettes 64 samples in volumes ranging from 0.5-10 [micro]l. The unit is useful for all 384-well liquid handling, including PCR and microarray techniques, as it allows pipetting of a large number of samples ...
Near-infrared small animal imager.(Editor's Choice)
Jul 01, 2008 ... [ILLUSTRATION OMITTED] The Pearl Imager (LI-COR Biosciences) features a CCD-based optical system specifically designed for in vivo imaging in the near-infrared (NIR) spectral region where tissue autofluorescence and light scattering are low. Signal detection is optimized for ...
Digital protein MS sample prep, analysis.(Editor's Choice)
Jul 01, 2008 ... [ILLUSTRATION OMITTED] ProteomeChip technology fractionates proteins or peptides by parallel isoelectric focusing on dPC chips run on the dPC Fractionator for mass spec analysis and Western blotting. Simply reduce, alkylate and desalt samples before addition to the dPC running ...
Multiplexed ELISA arrays.(Editor's Choice)
Jul 01, 2008 ... Quansys Bioseiences and Cell Signaling Technology (CST) have teamed up to provide CST's validated antibody pairs and Quansys' multiplex ELISA technology in a single product: Quansys Q-Plex Cell Signaling Arrays. The new ELISA-based tests feature four distinct capture antibodies bound to ...
Peptide libraries--an enabling tool for screening applications: high throughput screening of peptide libraries is now affordable.(Biochemicals & Kits)
Jul 01, 2008; Fillon, Yannick ... Peptide libraries have long been shunned as drug discovery tools, as production costs were often prohibitive and development tools, such as public databases or algorithms for epitope mapping, were not readily available. These limitations have been overcome, and screening of ...
Apoptosis monitoring assay.(Focus: Immunochemical)
Jul 01, 2008 ... This assay monitors induction and progression of apoptosis and provides all necessary reagent components in a single cocktail. Users can discern between early and late stage apoptotic cells with minimal possible sources of error. The reformulated reagent obviates the need for pre-assay ...
DNA fragmentation assay.(Focus: Immunochemical)
Jul 01, 2008 ... Internucleosomal DNA fragmentation is a hallmark of apoptosis in mammalian cells. Apo-BrdU-IHCTM Kit is a two-color TUNEL (Terminal deoxynucleotide transferase dUTP Nick End Labeling) assay for labeling DNA breaks to detect apoptotic cells by immunohistochemistry. The kit contains ...
Universal cell migration assembly kit.(Focus: Immunochemical)
Jul 01, 2008 ... This universal cell migration assembly kit features cell seeding stoppers to generate real-time results (chemokinesis or 2-D closure studies). A 96-well plate can be coated with any Extracellular Matrix (ECM) component to create a migration or invasion assay. To create a 2-D closure assay, ...
Immunofluorescent signal amplification.(Focus: Immunochemical)
Jul 01, 2008 ... [ILLUSTRATION OMITTED] Signal amplification reagents, for the Biocare Medical DyLight family of immunofluorescent (IF) Detection Kits, increase fluorescent signal 3 to 5 fold when added to standard fluorescent detection kits, advance identification of low abundance proteins, and ...
Custom media for yeast, fungi.(Product News: Biochemicals & Kits)
Jul 01, 2008 ... [ILLUSTRATION OMITTED] Customization services associated with growth media for yeast, fungi, microbes, and similar organisms are available encompassing specialized ingredients and formulations as well as individualized pack sizes and container types. The media are ground, mixed, ...
Cell harvesting kit.(Product News: Biochemicals & Kits)
Jul 01, 2008 ... The Cultrex Kit is based on a non-enzymatic approach that prevents biochemical degradation during processing and overcomes the problems associated with extracting cells from BME or Laminin I in 3-D culture. The quality of the ...
Proteomics reagents, software suite.(Product News: Biochemicals & Kits)
Jul 01, 2008 ... This suite of integrated mass spectrometry-based solutions for conducting targeted quantitative proteomics studies includes software packages and consumables that enable scientists to effectively quantify ...
Non-isotopic hERG channel-blockage screening.(Product News: Biochemicals & Kits)
Jul 01, 2008 ... Predictor hERG Fluorescence Polarization Assay is a non-isotopic, homogenous kit for performing hERG ion channel blockage screening. Drug-induced long QT syndrome and adverse cardiotoxic affects have been linked with blockage of the human ethera-go-go related gene (hERG) channel. The assay ...
Prolactin assay.(Product News: Biochemicals & Kits)
Jul 01, 2008 ... [ILLUSTRATION OMITTED] Automated assay allows the measurement of prolactin in evaluating patients with reproductive disorders. It is a two-step immunometric assay with a measuring range of approximately 0.05-300 micrograms per liter. Quantitative concentrations of prolactin are ...
Colony screening for plasmid DNA with PCR.(Product News: Biochemicals & Kits)
Jul 01, 2008 ... [ILLUSTRATION OMITTED] PCR allows for the rapid release of plasmids from transformed bacteria for screening by polymerase chain reaction (PCR). There is no requirement for growing bacteria, performing "mini-preps" or purifying the plasmid DNA. Simply add the colony directly to ...