Bioscience Technology back issues from May 2006:
What is cancer research worth?(Editor's Note)
May 01, 2006; ... A press conference held during the American Association for Cancer Research annual meeting last month addressed the reduction in federal spending for cancer research for budget year 2006, and a likely further reduction in spending for 2007. There is cause for concern: cancer is the second ...
Stereomicroscope, transmitted light bases.(May's Innovations)
May 01, 2006 ... This line of stereomicroscopes with transmitted light bases provides illumination for a variety of applications. The all-purpose TL ST base incorporates a halogen illumination system that provides brighfield or pseudo-darkfield transmitted light viewing conditions. The stand minimizes ...
Kinase screening kit.(May's Innovations)
May 01, 2006 ... The HTRF KinEASE kinase assay development kit allows profiling and high-throughput screening of a large range of Ser/Thr kinases, major targets in drug discovery. The kit combines antibody and kinase substrates with homogeneous time resolved fluorescence (HTRF) technology. The overall ...
Automated proteomics workstation.(May's Innovations)
May 01, 2006 ... ProLink Express automated proteomics work-cell integrates all plate delivery and transfer operations with automated data tracking from initial bacterial colony picking through final protein expression and measurement. The system links all the components needed for DNA expression of gene ...
Water purification system.(May's Innovations)
May 01, 2006 ... The Milli-QAdvantage converts pure water to ultrapure water. Rather than purchasing separate production units, several final point-of-use polishers are available to match the required application. The production units can be placed on the bench, under the bench, or on a wall. The movable ...
Nanoliter dispensing system.(May's Innovations)
May 01, 2006 ... Single channel, non-contact nanoliter dispense system is available for the Hydra II line of automated pipettors. When coupled with the 96 or 384 channel positive displacement pipetting capabilities of the Hydra II, the single channel eDrop dispenser is useful for forensic genotyping, low ...
In vitro imaging system.(May's Innovations)
May 01, 2006 ... LI-COR Biosciences has introduced a new accessory and IRDye reagents for in vivo molecular imaging on its Odyssey Infrared Imaging System. The Odyssey MousePOD Imaging Accessory fits over the standard Odyssey scanning surface for in vivo imaging of up to three mice. Longitudinal studies ...
SNP multiplexing kit.(May's Innovations)
May 01, 2006 ... Based on single-based primer extension technology, the GenomeLab SNPStart primer extension kit is validated and optimized for multiplexing up to 10 SNPs in a single tube. Ideal for low- to medium-throughput applications, this kit provides a fast alternative to one-at-a-time four-color SNP ...
Assay system.(May's Innovations)
May 01, 2006 ... GreenScreen GC eukaryotic genotoxicity assay rapidly screens lead compounds. The assay system is designed for use early in drug discovery. In a recent study, 2698 proprietary compounds were tested, as well as 51 marketed pharmaceuticals. The yeast system was shown to effectively complement ...
Gene expression: better tools: more complex results.(Cover story)
May 01, 2006 ... Gene expression has become a mainstream technique in biology, medicine, and drug development. Broadly speaking, gene expression comes in two flavors: analytical and functional. The former refers to detecting and quantifying genes, especially by comparing two samples (treated/untreated, ...
Micro HPLC system.(HLPC Focus)
May 01, 2006 ... UltiMate 3000 Series chromatography systems (Dionex Corp.) feature a comprehensive range of modules, including five micro pump systems optimized for flow rates of 10 [micro]l/min to several ml/min. Fast separations are provided on 1-3 mm ID columns, achieving cycle times of less than 1 ...
Liquid chromatography system.(HLPC Focus)
May 01, 2006 ... The 1200 Series HPLC system (Agilent Technologies Inc.), a high-throughput configuration of the company's 1100 Rapid Resolution system, allows sequential execution of more than 2,000 samples per day without compromising data quality or method flexibility. The system offers more than 70 new ...
UPLC/MS system.(HLPC Focus)
May 01, 2006 ... The ACQUITY SQD Ultra Performance Liquid Chromatography/Mass Spectrometry (UPLC/MS) features the Waters SQbenchtop, single-quadrupole, atmospheric pressure ionization (API) mass detector for routine UPLC/MS analyses. IntelliStart Diagnostic Software tunes and calibrates the mass detector ...
2-dimensional HPLC series.(HLPC Focus)
May 01, 2006 ... HPLC series includes the 2D Micro-HPLC System for Proteome Analysis, the 2D HPLC for Bioanalysis (BA), and the 2D HPLC for NMR Sample Preparation. The systems incorporate Shim-pack MAYI Restricted Access Media (RAM) pretreatment columns that achieve de-proteinization and stability through ...
Finding Factor II and V Leiden polymorphisms with gold nanoparticles.(Application Note)
May 01, 2006; ... Abstract The method is based on hybridization of the target by allele-specific surface-immobilized capture probes and gene-specific oligonucleotidefunctionalized gold nanoparticle probes, followed by a signal amplification process for target detection. ********** ...
Colony picker.(PRODUCTS: Instruments & Systems)
May 01, 2006 ... CP7200 picks colonies at rates of up to 7,200 per hour. Software allows shifting from plate-to-plate and even run-to-run without re-calibration. Instrument footprint is 22" x 20". It is reliable, and utilizes a continuous configuration that provides simultaneous picking, inoculation, ...
Clinical data repository.(PRODUCTS: Instruments & Systems)
May 01, 2006 ... Combining information from multiple sources, this repository provides integration and reporting for clinical and non-clinical data that enables regulatory compliance. All aspects of the integration process can be managed--data access, transformation, persistence and distribution--in a ...
In-vitro imaging of protein biomarkers.(PRODUCTS: Instruments & Systems)
May 01, 2006 ... MALDI Molecular Imager facilitates in-vitro imaging of peptide and protein biomarker distributions in tissue sections and cell clusters. An autoFlex MALDI-TOF mass spectrometer equipped with smartbeam laser technology provides high-throughput MALDI Imaging. The system incorporates ...
Electronic pressure control module.(PRODUCTS: Instruments & Systems)
May 01, 2006 ... The VSO-EP is a module for precision control of critical system pressures. An automated alternative to manual pressure regulators, needle valves, flow controllers, and bleed orifices, it provides integral closed-loop proportional control for both dynamic and "set and forget" applications ....
Multi-mode potentiostat.(PRODUCTS: Instruments & Systems)
May 01, 2006 ... BioStat multi-mode potentiostat is compatible with most electrochemical sensors or electrodes, and allows independent amperometric or potentiometric measurements on four electrically-isolated channels. The system handles signals of either polarity, employing 2- or 3- electrode ...
Real-time PCR platform.(PRODUCTS: Instruments & Systems)
May 01, 2006 ... LightCycler 480 Real-Time PCR System (Roche Applied Science) is a multiwell plate-based platform for qualitative and quantitative detection of nucleic acids and genotyping. Interchangeable blocks are used for 96 or 384 samples. Building on Roche's capillary-based LightCycler ...
Informatics system integrates molecular modeling.(PRODUCTS: Instruments & Systems)
May 01, 2006 ... MolSAR (Molecular Structure Activity Relationships) molecular modeling technology has been integrated into the KnowItAll Informatics System (Bio-Rad Laboratories, Informatics Group. MolSAR uses Bayesian neural network technology to build in silico models for a wide range of end points such ...
HPLC detectors.(PRODUCTS: Instruments & Systems)
May 01, 2006 ... Surveyor Plus refractive index and fluorescence detectors enhance analytical capabilities when integrated with the Finnigan Surveyor Plus HPLC product line (Thermo Electron Corp.). The fluorescence detector monitors the emissions of fluorescence, phosphorescence and chemiluminescence, ...
Protein, peptide column.(PRODUCTS: Instruments & Systems)
May 01, 2006 ... ProPac HIC-10 separates proteins and peptides by hydrophobic interaction chromatography. The stationary phase consists of 5 gm, 300[Angstrom] pure spherical silica gel particles, which are functionalized with multi-dentate amide groups. Surface chemistry is optimized by the inclusion of ...
Sorbents, gels, cartridges.(PRODUCTS: Instruments & Systems)
May 01, 2006 ... This family of products for all phases of chromatography includes a selection of sorbents such as silica gels, bonded phases, aluminas, polymer resins and more. TLC ...
Pathway analysis software.(PRODUCTS: Instruments & Systems)
May 01, 2006 ... PathwayStudio Version 4.0 contains new tools for microarray data analysis and pathway dynamics simulation, as well as over 1000 reconstructed pathways. It scales from desktop to enterprise-wide, and allows scientists to reconstruct pathways, understand biology from microarray/proteomics ...
Electrophoresis products.(PRODUCTS: Instruments & Systems)
May 01, 2006 ... Injection molded electrophoresis product includes horizontal and vertical gel electrophoresis units, blotting units, comet assay and cellulose acetate systems, IEF systems, power supplies, DNA sequencers and geldocumentation systems for DNA, RNA agarose gel ...
Re-packaged media products.(Cell Culture Focus)
May 01, 2006 ... GIBCO has re-designed their media bottle labels and caps, both of which are now color-coded by product family to make it easy to identify the cell culture products they contain. The labels utilize internationally recognized industry symbols for information about ...
Human Neural Stem cell kit.(Cell Culture Focus)
May 01, 2006 ... Human Neural Stem Cell (NSC) Functional Identification Kit contains media supplements that can be used for the short-term maintenance, differentiation, and expansion of NSCs, and for their induction into astrocyte, neuron, and oligodendrocyte lineages. An antibody panel consisting of ...
Mammary epithelial cell media.(Cell Culture Focus)
May 01, 2006 ... Reformulated EpiCult-B is an optimized medium for the culture and characterization of mammary cells without the addition of cholera-toxin. The serum-free product is specifically formulated for the growth of human and mouse mammary luminal and myoepithelial cells, as well as clonogenic ...
Fluorescent labels.(Cell Culture Focus)
May 01, 2006 ... Chromeo Dyes exhibit broad Stokes shifts, stability toward photobleaching and pH, and low cell toxicity, making them useful as labels of biomolecules in cell culture staining experiments. Currently, ...
Normal peripheral blood cells.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... PoieticsPTMP Leukopaks are bags of fresh human blood cells collected from normal peripheral blood by automated apheresis in ACD-A anticoagulant and density gradient centrifugation. Each Leukopak contains a mixture of monocytes, lymphocytes, platelets, plasma and red cells. Leukopaks are ...
Tissue disruption/ RNA purification.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... Multi-enzymatic liquefaction of tissue (MELT) RNA isolation system enables hands-free disruption of multiple solid tissues in parallel without homogenization or tissue grinding. Thus, there is no equipment to clean between samples. Up to 10 mg of fresh or frozen tissue can be lysed at room ...
Membrane protein interactor screening system.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... With the DUALmembrane Screening System, full-length membrane integrated bait proteins are screened against cDNA library expressed prey proteins to identify interactions between potentially unidentified integral membrane and soluble proteins. This technology takes advantage of the ...
DNA polymerase.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... PrimeSTAR HS DNA polymerase provides high fidelity as well as an extended product length--8.5 kb for human genomic DNA and 22 kb for [lambda] DNA. It is suited for PCR cloning applications. Priming efficiency leads to ...
RNA/Protein Kit.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... AllPrep RNA/Protein Kit (Qiagen, Inc.) purifies total RNA and native protein simultaneously from the same sample of cultured cells. The purified RNA and protein provide high performance in downstream applications, such as Western blotting, enzyme assays, and real-time RT-PCR. For ...
Nitrite assay kit.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... Ready-to-use colorimetric nitrite assay detects phosphate concentrations from 2 [micro]m to 10 [micro]m and can be performed in cuvettes or microplates. Nitric Oxide is detected in biological fluids via nitrite. Additionally, nitrate can be reduced to nitrite by NADPH in the presence of ...
Monoclonal, for cellular function analysis.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... IOTest CD85d-(ILT4)-PE conjugated monoclonal antibody is useful in basic research on leucocyte function, dendritic cells, immunosuppression, tolerogenicity and maternofetal tolerance. ILT4 is selectively expressed on myelomonocytic cells and binds to classical and non-classical human ...
Human cDNA Library Panel.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... Human SpliceMiner cDNA Library Panel simplifies the process of discovering rare and unique alternative splice forms. The panel consists of ~ 4.6 million primary cDNA clones derived from 15 cDNA plasmid libraries representing 28 cancer cell lines and 32 normal human tissues, including 14 ...
Kinase Assay.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... Transcreener KINASE Plus Assay is a far-red competitive fluorescence polarization immunoassay, optimized for enzymatic assays which generate ADP and require high concentrations of ATP (up to 250 [micro]M and above). Developed originally to follow the progress of kinase and ATPase ...
Human, mouse, rat arrays.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... OpArrays, pre-printed microarrays for the human, mouse (Mus musculus), rat (Rattus novegicus), and Arabidopsis thaliana genomes, are part of a line that includes ...
Comet Assay control cells.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... Stable control cell preparations contain known levels of DNA damage for use as standards when performing the CometAssay. When they are electrophoresed in the CometAssay, the controls consistently produce the same comets with predetermined tail and Olive moments and ...
Protein sample prep.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... Protea Explorer protein sample preparation instrument integrates the various steps of protein sample preparation, from a single gel-spot to the mass spectrometer. Processing time is a few hours. The enclosed system permits a large menu of solution-based sample preparation applications, ...
High-content bio-imaging.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... This collection of monoclonal anti-body reagents has been tested and certified for utility in automated bio-imaging (high content) and microscopy applications. To be certified, each antibody must pass a number of tests that include exceeding a signal intensity threshold over background in ...
Peplides, for protein analysis.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... HeavyPeptides, isotopically-labeled, non-radioactive custom peptides offered for mass and NMR spectroscopy, can be used as sequence-identical internal weight standards for quantitation of proteins and protein mixtures. HeavyPeptide AQUA kits can be prepared with covalent modifications, ...
miRNA Isolation, Labeling Kit.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... The miRacULS miRNA Isolation and Labeling Kit combines the upstream isolation of small RNA from tissue or cultured cells and the reagents necessary to label these samples for DNA microarray analysis. The kit is available with the ULS labeling molecule bound to Cy3 and Cy5 dyes licensed ...
Acylcarnitine profiling assay.(PRODUCTS: Biochemicals & Kits)
May 01, 2006 ... Acylcarnitine profiling platform assists in drug discovery and development for a range of critical diseases and metabolic conditions. Acylcarnitines are intermediates in mitochondrial beta-oxidation, or fat burning. Their measurement in serum or plasma provides information on changes in ...
High throughput RNA quality control: the multi-channel, real-time, light-induced fluorescent detection capillary electrophoresis system provides a reliable method for routine RNA quality analysis.(Application Note)
May 01, 2006; ... Importance of RNA quality analysis Determining the integrity of RNA is an essential step before gene expression analysis, because RNA quality can have a tremendous effect on downstream microarray analysis, data interpretation of gene expression profiling, and disease diagnosis ....
Hot plates, stirrers.(Sample Processing Focus)
May 01, 2006 ... Corning hot plates, stirrers and stirring hot plates provide precise temperature as measured in the liquid being heated (as opposed to the plate top) and stirring speeds accurate to +5%. Digital displays indicate when set temperature and stirring speed ...
Robotic centrifuge.(Sample Processing Focus)
May 01, 2006 ... Robotic version of the Rotanta 46RSC refrigerated centrifuge offers computer control and and maximum capacity of four, 750-ml round bottom containers, 16 microtiter plates, or four deep-well plates. Designed for automatic sample processing, it performs routine laboratory tasks efficiently ...
Swing-out rotor for microtubes.(Sample Processing Focus)
May 01, 2006 ... The C0230-HLA-RAis 12 position swingout rotor is suited for HLA applications or any protocol requiring separation of the pellet to the bottom of a microtube. Available for both the Hermle Z233-M2 and the refrigerated Z233-MK2, it can reach speeds of up to 10,500 rpm or 9,600 x g. Speed can ...
Multiple position microplate mixer.(Sample Processing Focus)
May 01, 2006 ... The MultiMicroPlate Genie, with capacity for up to four operates at Speeds from 750-3200 rpm. This combination of features ensures complete mixing in each microplate well, even in 384-well formats. Any type of skirted microplate with a standard SBS recommended footprint may be used, ...
Non-invasice micro injection.(Sample Processing Focus)
May 01, 2006 ... SLAM (Soft Lipid-Assisted Microinjection) pipette provides micro-injection capability without the need to impale or rupture a cell membrane. A lipid coating on the tip simply fuses with a cell membrane, allowing pipette contents to be non-invasively injected into the cell cytoplasm ....
Ventilator.(Sample Processing Focus)
May 01, 2006 ... MiniVent Ventilator is ideal for mice, but may also be used for peri-natal rats. Respiration rate is adjustable from 60 to 400 strokes per minute and tidal volume is adjustable from 30 to 350 microliters. The palm-sized unit ...
Pre-saturated, sterile wipers.(Sample Processing Focus)
May 01, 2006 ... A complete line of dry, pre-saturated and sterile KIMTECH PURE Wipers is available for all cleanroom environments. CL3 wipers can be used in ISO Class 3 or higher cleanroom environments. The dry wipers are 100% continuous filament doubleknit polyester. They absorb liquids on contact while ...
Plastic cryogenic vials.(Sample Processing Focus)
May 01, 2006 ... Three styles of cryogenic vials are available: internal thread, external thread, and plug seal. The vials come in 1.2, 2.0, 4.0 and 5.0 ml sizes. All vials are manufactured from polypropylene for use at temperatures to -196 C, have a one-turn open/closure cap and most vials accept cap ...
Stainless steel LC fittings.(Sample Processing Focus)
May 01, 2006 ... This line of two-piece stainless steel chromatography fittings rated to 28,000 psi (1930 bar) is designed for UPLC. The fittings work in standard 10/32 coned ...
Hydrophilic PTFE membranes.(Sample Processing Focus)
May 01, 2006 ... Omnipore membrane is compatible with virtually all solvents, acids, and alkaline solutions. Membrane filters are available as 13 mm, 25 mm, and 47 mm cut disks in pore sizes from 0.1-10 [micro]m. The LCR membrane is ...
Low flow, pulseless fluid delivery.(Sample Processing Focus)
May 01, 2006 ... The CeramPump No-Valve Fluid Control principle combined with Phase-Canceling Technology eliminates pulsation for continuous fluid metering down to 5 [micro]1/min. Fully programmable dispensing system is controlled by precision stepper motors. Phase-Canceling Technology uses 3 separate ...
Vacuum pumps.(Sample Processing Focus)
May 01, 2006 ... With a chemical resistant and oil-free PTFE diaphragm, the BuchiVac V-700 and V-710 vacuum pumps are suitable for use with all gases and vapors associated with any lab application. The units come with a choice of a solvent condensing apparatus, a ...
Steam sterilizers.(Sample Processing Focus)
May 01, 2006 ... Finn-Aqua GMP GMP Bio Pharma Sterilizers (BPS) are offered in multiple sizes, from 9.7 cubic feet to 294 cubic feet, each with a choice of sterilization cycle options. All units have a choice of the Allen Bradley or Siemens programmable logic controls. Chamber design, based on the Finn ...
Conical tube centrifuge adapter.(Sample Processing Focus)
May 01, 2006 ... Beckman Coulter Allegra X-15R and X-12 Series benchtop centrifuges now feature an adapter that spins 50-ml conical tubes. The adapter accommodates 28 tubes per run in a bio-certified, self-balancing rotor and is suited for cell harvesting and blood separation ...
Positive displacement pumps.(Sample Processing Focus)
May 01, 2006 ... Cheminert Model M6 and M50 pumps produce bidirectional pulse-less flow with a range of over six orders of magnitude (10 nl/min to 10 ml/min for the M6; 50 [micro]1/min to 50 ml/min for the M50). The positive displacement units are self-priming and tolerate any gas which may find its way ...
Tungsten microtools.(Sample Processing Focus)
May 01, 2006 ... Microtools manufactured from tungsten are hand ground, lapped and polished. Applications for the tools extend to medical research, microscopy, microbiology, micro-biochemistry, specimen manipulation and spectroscopy. The line consists of: a needle, a chisel, a spade, 20[degrees] and ...
2D barcode readers.(Sample Processing Focus)
May 01, 2006 ... VisionMate Lite 2D bar-code reader plugs into a computer keyboard's PS2 or AT port and automatically transfers data directly to the cursor location in any active application each time a ...