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Biotech Week articles from October 2008

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<a href="http://www.highbeam.com/Biotech+Week/publications.aspx?date=200810" title="Articles and back issues from Biotech Week">Biotech Week articles</a>

Biotech Week back issues from October 2008:

Migraine linked to blood clots in veins.

Oct 01, 2008 ... People with migraines may also be more likely to develop blood clots in their veins, according to a study published in the September 16, 2008, issue of Neurology[R], the medical journal of the American Academy of Neurology (see also American Academy of Neurology). In the ...

New tool to speed cancer therapy approval available.

Oct 01, 2008 ... Although cancer remains a leading cause of death in America, it can take up to 12 years to bring a new anti-cancer agent before the FDA and the success rate for approval is only five to 10 percent. That means many research hours and dollars are wasted chasing avenues that will not bring ...

Massage therapy may have immediate positive effect on pain and mood for advanced cancer patients.

Oct 01, 2008 ... A new study from the National Institutes of Health finds that massage therapy may have immediate benefits on pain and mood among patients with advanced cancer. The study appears in the September 16, 2008 issue of Annals of Internal Medicine (see also American College of Physicians). ...

AGA Institute statement: Data support CT colonography as viable colorectal cancer screening option.

Oct 01, 2008 ... Death from colorectal cancer is highly preventable with effective screening and early detection. Many screening options are available, each with advantages and disadvantages, but half of eligible patients still do not participate in colorectal cancer screening. For that reason, a goal of ...

Older problem gamblers may face greater suicide risk than younger counterparts, study finds.

Oct 01, 2008 ... Compared to their younger counterparts, older problem gamblers who ask casinos to bar them from returning are three to four times more likely to do so because they fear they will kill themselves if they don't stop betting, according to a new study (see also American Psychological ...

Directing a driver's gaze results in smoother steering.

Oct 01, 2008 ... Typically, drivers gaze along a curve as they negotiate it, but they also look at other parts of the road, the dashboard, traffic signs and oncoming vehicles. A new study finds that when drivers fix their gaze on specific targets placed strategically along a curve, their steering is ...

Hopkins Children's study: Parents of dying newborns need clearer explanation of options.

Oct 01, 2008 ... Parent-doctor discussions about whether to maintain or withdraw life support from terminally ill or severely premature newborns are so plagued by miscommunication and misunderstanding that they might as well be in different languages, according to a small but potentially instructive new ...

Looking vs. seeing.

Oct 01, 2008 ... The superior colliculus has long been thought of as a rapid orienting center of the brain that allows the eyes and head to turn swiftly either toward or away from the sights and sounds in our environment. Now a team of scientists at the Salk Institute for Biological Studies has shown that ...

UT Southwestern specialist leads effort to craft first professional guidelines for regarding earwax.

Oct 01, 2008 ... The age-old advice to routinely clean out earwax is discouraged under the first published guidelines from health care professionals about removing wax from the ear (see also UT Southwestern Medical Center). "Unfortunately, many people feel the need to manually remove earwax, ...

Social psychology can be used to understand nuclear restraint.

Oct 01, 2008 ... Social psychology is the study of how people and groups interact. A new study in the journal International Studies Review shows how social psychology can help us better understand the puzzle of nuclear restraint and uses the case of Japan to illustrate social psychology on nuclear ...

Copper Conferencing Selected as a PHONE+ Top 50 Channel Program.

Oct 01, 2008 ... PHONE+ magazine, a resource for the telecommunications indirect sales channel, announced that Copper Conferencing has been selected as a Top 50 Channel Program. The results of this contest will be published in the magazine's 2008 Channel Program Guide special issue, due out Oct. 15 (see ...

Genomatica Breakthrough Replaces Petroleum With Sugar in Major Chemical Process.

Oct 01, 2008 ... San Diego-based Genomatica Inc., a sustainable chemical company, has proven a novel bio-manufacturing process capable of producing thousands of tons of a commodity chemical in a single facility. The foundational chemical, 1,4-butanediol (BDO), is a key raw material in the manufacturing of ...

Hatteras and ANDA Lead Fast-Growing Carrier Ethernet Access Platform Market Segments in 2Q08, Heavy Reading Reports.

Oct 01, 2008 ... Worldwide sales of copper-based carrier Ethernet access platforms rose 74% year-over-year to $208 million in the four-quarter period ending in 2Q08, according to the new Carrier Ethernet Access Platform (CEAP) Quarterly Market Tracker service published by Heavy Reading ( ...

Neurofocus Appoints Stephen Kosslyn to Its Advisory Board.

Oct 01, 2008 ... NeuroFocus, Inc., the world's leading company in the field of neurological testing for marketing research, announced that professor Stephen Kosslyn, Ph.D. has joined the firm's Advisory Board (see also NeuroFocus, Inc.). He is the John Lindsley Professor of Psychology and former ...

A Piece of Mind: Vitamin B12 May Protect the Brain in Old Age.

Oct 01, 2008 ... Vitamin B12 may protect the brain in old age and reduce risk of dementia, according to a new study by University of Oxford researchers. Published in the new issue of Neurology, the study determined people with higher blood levels of vitamin B12 were six times less likely to experience ...

Newsweek and Fedtech Win PRSA 2007 Excellence in Technology Journalism Awards.

Oct 01, 2008 ... Kindle, Amazon's entry into the e-book market, and bringing technology to the Navajo Nation are topics of two award-winning articles selected at this year's Public Relations Society of America (PRSA) Awards for Excellence in Technology Journalism. Steven Levy, senior editor, Newsweek ...

SunLink Health Systems, Inc. to Amend Current Report on Form 8-K.(Report)

Oct 01, 2008 ... SunLink Health Systems, Inc. announced that it expects the audited financial statements of its Carmichael's Cashway Pharmacy, Inc subsidiary to be restated to adjust the pre-acquisition periods previously reported in SunLink's Current Report on Form 8-K filed on July 9, 2008 (see also ...

Studies from D.H. Lee et al in the area of abscess described.(Report)

Oct 01, 2008 ... "The purpose of this study is to demonstrate the feasibility, safety, and success of percutaneous paracoccygeal catheter drainage of deep pelvic abscesses using a combination of sonography and fluoroscopic guidance. From April 2005 to December 2006, under sonography and fluoroscopic ...

Researchers at Korea University have published new data on acid reflux disease.

Oct 01, 2008 ... " The morbidity and mortality of anastomotic complications after esophagectomy have gradually decreased in recent years. However, swallowing difficulties and reflux continue to burden patients jeopardizing their quality of life," scientists in Seoul, South Korea report (see also Acid ...

Findings from Kyungpook National University, Medical Department advance knowledge in acne vulgaris.

Oct 01, 2008 ... "Acne is a complex, chronic and common skin disorder of pilosebaceous units. Although it is known that exacerbation of acne results from emotional stress, the nature of the association between stress and acne remains unclear," researchers in South Korea report (see also Acne Vulgaris). ...

Research from C.L. Chen and co-researchers in the area of acne vulgaris described.(Survey)

Oct 01, 2008 ... In this recent report, researchers in the United States conducted a study "To examine preferences for acne-related outcomes in adolescents. Community-based, cross-sectional survey study." "Four public high schools in San Francisco, California. Volunteer sample of 266 adolescents ...

Research from R. Homberg et al has provided new information about actinomycosis.

Oct 01, 2008 ... "Actinomnycosis is a rare infection mainly of the head and neck region (cervicofacial actinomycosis). The cause of this infection is bacterial invasion of the host's mucosal barrier with consecutive infiltration of the surrounding tissues," scientists writing in the journal Aktuelle ...

Reports summarize acute pancreatitis research from E. Sathiaraj and co-authors.

Oct 01, 2008 ... " In mild acute pancreatitis, traditional treatment has been initial fasting and oral refeeding with clear liquids to prevent adverse gastrointestinal events such as pain. The diet is gradually progressed to soft solids and hospital discharge is planned based on patients' tolerance to a ...

Studies from Ernst-Moritz-Arndt University provide new data on acute pancreatitis.

Oct 01, 2008 ... "Leukocyte infiltration is an early and critical event in the development of acute pancreatitis. However, the mechanism of leukocyte transmigration into the pancreas and the function of leukocytes in initiating acute pancreatitis are still poorly understood," scientists in Greifswald, ...

Scientists at Medical University of Silesia describe research in acute peritonitis.

Oct 01, 2008 ... "An early and reliable diagnostic procedure for acute peritonitis in patients on peritoneal dialysis (PD) without typical clinical symptoms remains an important challenge in modern nephrology. During the first days of peritonitis, establishing the diagnosis based on peritoneal effluent ...

Findings from C. Jongen and co-authors provide new insights into addiction medicine.(Report)

Oct 01, 2008 ... " The dopamine D-2 receptor (D2R) is important in the mediation of addiction. [I-123]iodobenzamide (IBZM), a SPECT ligand for the D2R, has been used for in vivo studies of D2R availability in humans, monkeys, and rats," scientists writing in the European Journal of Nuclear Medicine and ...

New addiction medicine research from J.J. Jalbert and colleagues discussed.

Oct 01, 2008 ... According to a study from the United States, "The risk of adverse events among alcohol-interactive medication users can occur with one standard alcoholic drink. Research on the extent to which this occurs is scant." "To examine the prevalence and correlates of concurrent ...

New addiction medicine research from Oregon Health & Science University described.

Oct 01, 2008 ... "A common expression of neuroadaptations induced by repeated exposure to addictive drugs is a persistent sensitized behavioral response to their stimulant properties. Neuroplasticity underlying drug-induced sensitization has been proposed to explain compulsive drug pursuit and consumption ...

New adenoma data have been reported by scientists at University of London, Imperial College.(Clinical report)

Oct 01, 2008 ... " Colonoscopy has a known miss rate for polyps and adenomas. High definition (HD) colonoscopes may allow detection of subtle mucosal change, potentially aiding detection of adenomas and hyperplastic polyps," scientists in Harrow, the United Kingdom report (see also Adenoma). " ...

Study results from University of Ulm broaden understanding of adenomatous polyp.(Report)

Oct 01, 2008 ... "This study was designed to prospectively examine functional outcome, quality of life, and patients' personal experiences and adjustment to functional changes during the first year after prophylactic surgery. Twenty-one consecutive patients with familial adenomatous polyposis were examined ...

Studies from N. Shehab and colleagues yield new information about adverse drug reactions.

Oct 01, 2008 ... "Drug-related adverse events are an underappreciated consequence of antibiotic use, and the national magnitude and scope of these events have not been studied. Our objective was to estimate and compare the numbers and rates of emergency department (ED) visits for drug-related adverse ...

Research conducted at Ohio State University has updated our knowledge about aggression.

Oct 01, 2008 ... "Purpose of review The aim of this article is to review reports of aggressive challenging behaviour in individuals with intellectual disability from September 2006 to March 2008. Recent findings Studies continued to demonstrate the prevalence and significance of aggressive challenging ...

New aging research from M.E. Calhoun and co-researchers described.

Oct 01, 2008 ... "Age-related impairments in hippocampus-dependent learning and memory tasks are not associated with a loss of hippocampal neurons, but may be related to alterations in synaptic integrity. Here we used stereological techniques to estimate spine number in hippocampal subfields using ...

New aging research reported from A.M. Barrett and co-authors.

Oct 01, 2008 ... According to a study from the United States, "Healthy subjects demonstrate leftward bias on visual-spatial tasks. However, young controls may also be left-biased when drawing communicatively, depicting the subject of a sentence leftward on a page relative to the sentence object, that is, a ...

Recent findings in aging described by researchers from University of Utrecht.

Oct 01, 2008 ... "Distortions in the rest-activity rhythm in aging are commonly observed. Neurodegenerative changes of the suprachiasmatic nucleus have been proposed to underlie this disrupted rhythm," scientists in Netherlands report (see also Aging). "However, based on previous studies, it can ...

Reports from University of Heidelberg add new data to research in aging.

Oct 01, 2008 ... According to a study from Heidelberg, Germany, "Dendritic spines are major sites of excitatory synaptic transmission and changes in their densities have been linked to alterations in learning and memory. The neurotrophins brain-derived neurotrophic factor and neurotrophin-3 and their ...

Research on aging published by J. Liu et al.

Oct 01, 2008 ... "Data collected from the sensory test score evaluation of bottled lager beer, together with the chemical components related to aging, including carbonyl compounds, higher alcohols, unsaturated fatty acid, organic acids, alpha-amino acids, dissolved oxygen, and staling evaluation indices, ...

Researchers from Tufts University, Department of Agriculture publish findings in aging.(Report)

Oct 01, 2008 ... "This Study examined the influence of lower extremity body composition and muscle strength on the severity of mobility-disability in community-dwelling older adults. Fifty-seven older males and females (age 74.2 +/- 7 yrs; BMI 28.9 +/- 6 kg/m(2) underwent an objective assessment of lower ...

Scientists at Yale University publish new data on aging.(Report)

Oct 01, 2008 ... "The decline in motor performance that accompanies advanced age has unclear neurobiological substrates but may relate, in part, to degeneration of the nigrostriatal dopamine system. This research tested the hypothesis that striatal dopamine transporter (DAT) availability in healthy elderly ...

Studies from P. Giannakopoulos and colleagues provide new data on aging.

Oct 01, 2008 ... "Den Dunnen et al. [den Dunnen, W.F.A., Brouwer, W.H., Bijlard, E., Kamphuis, J., van Linschoten, K., Eggens-Meijer, E., Holstege, G., 2008," scientists writing in the journal Neurobiology of Aging report (see also Aging). "No disease in the brain of a 115-year-old woman ....

Study data from Yale University, Medical Department update understanding of aging.

Oct 01, 2008 ... According to recent research from the United States, "A quantitative framework to assess harms and benefits of candidate medications in the context of drugs that a patient is already taking is proposed. Probabilities of harms and benefits of a given medication are averaged to yield a ...

Research conducted at M.J. Zhu and co-researchers has updated our knowledge about alcoholism.

Oct 01, 2008 ... In this recently published study, investigators in Shanghai, People's Republic of China conducted a study "To investigate oxidative stress and lipid peroxidation in hepatic steatosis and the underlying implications in pathological mechanisms of non-alcoholic fatty liver disease (NAFLD) ....

New allergies findings from St. Louis University, Medical Department published.

Oct 01, 2008 ... According to a study from the United States, "The practicing allergist has the unique opportunity to see an extraordinary variety of fascinating patients. Identifying the precise cause of the patient's complaints makes for a satisfying intellectual endeavor." "This is ...

New allergies study findings have been reported by researchers at University of Manitoba.

Oct 01, 2008 ... "Recently, we have shown that allergen-induced airway hyperresponsiveness (AHR) after the early (EAR) and late (LAR) asthmatic reaction in guinea pigs could be reversed acutely by inhalation of the Rho kinase inhibitor Y-27632. The present study addresses the effects of pretreatment with ...

New allergies study findings have been reported from F.X. Ble et al.

Oct 01, 2008 ... In this recent article published in the journal Radiology, scientists in Basel, Switzerland conducted a study "To demonstrate the feasibility of using proton magnetic resonance (MR) imaging to noninvasively detect extravascular and luminal fluid in a murine model of allergen-induced ...

Research from Stallergenes SA provide new insights into allergies.(Report)

Oct 01, 2008 ... According to a study from Antony, France, "In this study, we used HLA-DRB1*0101, DRB1*0401, and DRBI*1501 peptide tetramers combined with cytokine surface capture assays to characterize CD4(+) T cell responses against the immunodominant T cell epitope (peptide 141-155) from the major birch ...

Scientists at University of Calabria describe research in allergies.

Oct 01, 2008 ... According to recent research from Italy, "Ole e 1 (NCBI entry gi vertical bar 14424429) is the major allergen of Oleaceae family. Multiple isoforms and variants are present in varying degrees of distribution." "In this report, we present a new approach to the resolution of ...

Studies from A. Palacin and co-authors have provided new information about allergies.

Oct 01, 2008 ... According to recent research published in the journal Annals of Allergy Asthma & Immunology, "Baker's asthma is a frequent IgE-mediated occupational disorder mainly provoked by inhalation of cereal flour. Allergy to kiwifruit has being increasingly reported in the past few years." ...

Data on Alzheimer disease reported by researchers at Cleveland Clinic.

Oct 01, 2008 ... According to a study from the United States, "Genetic studies have demonstrated very high heritability for Alzheimer's disease (AD) risk in humans; however, these genetic contributions have proven extremely challenging to map in large studies of AD patients. Processing of the amyloid ...

New findings from Duke University in the area of Alzheimer disease published.(Report)

Oct 01, 2008 ... "There is concern that life is curtailed when patients with Alzheimer's disease (AD) are institutionalized. To determine whether placement in a nursing home reduces their remaining years of life, we examined the experience of White patients with AD (n = 890) enrolled in the Consortium to ...

Research from University of Texas broadens understanding of Alzheimer disease.

Oct 01, 2008 ... In this recently published article, scientists in the United States conducted a study "To ascertain the clinical utility of language examination by psychiatrists in evaluating Alzheimer's disease (AD) patients. Data collected between 1986 and 2003 from a standardized psychiatric ...

Researchers from Karolinska University describe findings in Alzheimer disease.(Clinical report)

Oct 01, 2008 ... According to recent research from Huddinge, Sweden, "The effect of galantamine treatment on cortical acetylcholinesterase (AChE) activity and nicotinic receptor binding was investigated by positron emission tomography (PET) in 18 patients with mild Alzheimer's disease (AD) in relation to ...

Studies from University College update current data on Alzheimer disease.(Report)

Oct 01, 2008 ... According to a study from Dublin, Ireland, "Macroautophagy, a major pathway for organelle and protein turnover, has been implicated in the neurodegeneration of Alzheimer's disease (AD). The basis for the profuse accumulation of autophagic vacuoles (AVs) in affected neurons of the AD brain, ...

Research data from B.A. Strange and colleagues update understanding of amnesia.

Oct 01, 2008 ... "A polymorphism in the human serotonin transporter (5-HTT) gene is implicated in susceptibility to anxiety and depression and in enhanced emotion-induced activation in the amygdala," researchers in London, the United Kingdom report (see also Amnesia). "A role for 5-HTT ...

Research on amnesia published by W.J. Liu et al.

Oct 01, 2008 ... "The adenylate cyclase/cAMP signaling pathway and adult mushroom bodies (MBs) have been shown to play an important role in sleep regulation in Drosophila. The amnesiac (amn) gene, encodes a neuropeptide that is homologous with vertebrate pituitary adenylate cyclase-activating peptide ...

Study data from M. Verfaellie et al provide new insights into amnesia.(Report)

Oct 01, 2008 ... According to a study from the United States, "While it is well known that repetition can enhance memory in amnesia, little is known about Which forms of repetition are most beneficial. This study compared the effect on recognition memory of repetition of words in the same semantic context ...

Scientists at University of Toronto publish research in amyotrophic lateral sclerosis.(Report)

Oct 01, 2008 ... According to recent research published in the journal Neurobiology of Aging, "There is increasing evidence of a clinical, neuropathological and genetic overlap between frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). We conducted a case-control study using a UK ...

Data on anatomy discussed by researchers at Ankara University, Medical Department.(Report)

Oct 01, 2008 ... "Satisfactory analgesia cannot be achieved in every obturator nerve block. To attempt to improve the success rate of obturator nerve block, this study describes the detailed anatomy of the obturator region and canal," scientists in Ankara, Turkey report (see also Anatomy). ...

New anatomy study findings have been reported by scientists at University of Vienna.

Oct 01, 2008 ... "Scanning Electron Microscopy (SEM) revealed that the palate of Cuora amboinensis has a flat surface with keratinized and non-keratinized regions. Keratinization is reflected in disc-shaped keratinized dead cells with rough microplicae on the surface, and is concentrated close to the ...

Research conducted at Aristotle University, Medical Department has provided new information about anatomy.

Oct 01, 2008 ... According to a study from Thessaloniki, Greece, " The superior hypogastric plexus (SHP) that is formed anterior to the aorta and the sacral promontory and is located anterior to the L5-S1 vertebrae, normally continues as the inferior hypogastric plexus. Several variations have been ...

Data from H.W. Steenland and colleagues advance knowledge in anesthesia.

Oct 01, 2008 ... According to recent research published in the Journal of Neuroscience, "The transmission of rhythmic drive to respiratory motoneurons in vitro is critically dependent on glutamate acting primarily on non-NMDA receptors. We determined whether both non-NMDA and NMDA receptors contribute to ...

Recent findings from S. Yagi and co-authors highlight research in anesthesia.

Oct 01, 2008 ... According to recent research from Tokyo, Japan, "Swallowing is a reflex that receives sensory information from the peripheral nerves and from the cerebral cortex. The aim of the present study was to investigate whether the sensory input from anterior teeth affects the functional ...

Research from J. Fabregatlopez and co-researchers yields new findings on anesthesia.

Oct 01, 2008 ... According to recent research from Murcia, Spain, "The ProSeal laryngeal mask airway (PLMA) has been used routinely for anaesthesia and for difficult airway management including airway rescue in non-fasted patients. Compared with the classic laryngeal mask airway the PLMA increases ...

Research from University of Freiburg provide new insights into anesthesia.

Oct 01, 2008 ... According to recent research from Freiburg, Germany, "Although rare, infectious complications from regional anesthesia and analgesia can be devastating. The literature on this topic consists primarily of surveys, case reports, case series, and studies in which used supplies were cultured." ...

New aneurysm data have been reported by researchers at University of Nottingham.

Oct 01, 2008 ... In this recently published article, scientists in Nottingham, the United Kingdom conducted a study "To evaluate whether multidetector computed tomographic angiography (CTA) scanners can detect a clinically significant intracranial aneurysm in the circle of Willis causing an isolated third ...