Biotech Week back issues from November 2008:
Studies from L. Jelev and colleagues provide new data on catheterization.
Nov 05, 2008 ... "In routine clinical practice the variations of the radial artery are the main reason for technical failure during transradial catheterization. If these variations are well documented, however, they do not represent a problem in the transradial approach," researchers in Sofia, Bulgaria ...
Researchers from Mayo Clinic describe findings in celiac disease.
Nov 05, 2008 ... According to recent research published in the journal Clinical Gastroenterology and Hepatology, "There is an elevated prevalence of celiac disease (CD) in family members (FMs) of CD patients, but most prior studies have been done on selected populations. Our aim was to determine the ...
Medical University of South Carolina details research in cell proliferation.
Nov 05, 2008 ... "Sulfiredoxin (Srx) is one of a family of low molecular weight sulfur containing proteins linked with maintenance of cellular redox balance. One function of Srx is the reduction of cysteine sulfinic acid to sulfenic acid in proteins subject to oxidative stress," scientists in the United ...
New cell proliferation research reported from University of Rochester, Medical Department.
Nov 05, 2008 ... According to a study from the United States, "Cortico-ventral basal ganglia circuitry is associated with a variety of mental health disorders including obsessive-compulsive disorder and drug addiction, disorders that emerge during childhood through young adulthood, a period in which the ...
Studies from Ohio State University provide new data on cell proliferation.
Nov 05, 2008 ... According to recent research from the United States, "Transforming growth factor-beta 1 (TGF-beta 1) is a potent inhibitor of muscle cell proliferation and differentiation. Decorin, a small proteoglycan in the extracellular matrix, binds to TGF-beta 1 and modulates the activity of TGF-beta ...
Study results from University of Parma update understanding of central nervous system disorders.
Nov 05, 2008 ... "The pharmacological profiling of potent histamine H-3-ligands initiated in a previous study is completed here. In vitro functional and binding studies revealed that several derivatives were selective H-3-antagonists with nanomolar potency at human and guinea-pig histamine receptors, able ...
Research reports on central nervous system infection from S. Grayo and colleagues provide new insights.
Nov 05, 2008 ... "Listeriosis is a rare but life-threatening infection. A favorable outcome is greatly aided by early administration of antibiotics with rapid bactericidal activity against Listeria monocytogenes," researchers in Paris, France report (see also Central Nervous System Infection). ...
New research on Chagas disease from C.F. Dasilva and co-authors summarized.(Report)
Nov 05, 2008 ... According to a study from Brazil, "Aromatic diamidines are DNA minor groove-binding ligands that display excellent antimicrobial activity against fungi, bacteria, and protozoa. Due to the currently unsatisfactory chemotherapy for Chagas' disease and in view of our previous reports ...
Research from University of Toronto reveals new findings on Chagas disease.
Nov 05, 2008 ... "After a blood meal, Rhodnius prolixus undergoes a rapid diuresis to eliminate excess water and salts. During the voiding of this primary urine, R. prolixus acts as a vector of Chagas' disease, with the causative agent, Trypanosoma cruzi, infecting the human host via the urine. Diuresis in ...
Scientists at University of Massachusetts, Medical Department report research in cholecystitis.
Nov 05, 2008 ... According to a study from the United States, " We attempted to determine population-based outcomes of laparoscopic (LC) and open cholecystectomy (OC) for acute cholecystitis (AC). We used the National Hospital Discharge Surveys from 2000 through 2005." "Annual medical and ...
Findings in cholera reported from M. Tobindangelo and co-researchers.
Nov 05, 2008 ... According to recent research published in the journal Clinical Infectious Diseases, "From 2003 through 2007, Vibrio cholerae serogroup O75 strains possessing the cholera toxin gene were isolated from 6 patients with severe diarrhea, including 3 in Georgia, 2 in Alabama, and 1 in South ...
Research conducted at S. Sasaki and co-researchers has updated our knowledge about cholera.
Nov 05, 2008 ... According to recent research published in the American Journal of Tropical Medicine and Hygiene, "A cholera outbreak occurred in Lusaka city between November 28, 2003 and June 8, 2004, and 6,542 cases with 187 deaths (case fatality rata: 2.86) were reported. We analyzed the distribution of ...
Researchers from Massachusetts General Hospital report recent findings in cholera.
Nov 05, 2008 ... According to recent research published in the Journal of Infectious Diseases, "Infection with Vibrio cholerae induces durable immunity against subsequent disease, a process hypothesized to reflect anamnestic immune responses at the intestinal mucosa. The presence of antigen-specific memory ...
Reports summarize chromatography study results from N.V.V.S.S. Raman and co-researchers.
Nov 05, 2008 ... "A GC-MS method for the simultaneous determination of two process related toxic impurities viz. 2-(chloromethyl)-3,4-dimethoxypyridine hydrochloride (CDP) and dimethyl sulfate (DMS) and RP-LC for the routine determination of CDP in pantoprazole sodium (PPS) are presented. In GC-MS, a ...
Studies from Tongji University in the area of chromatography described.
Nov 05, 2008 ... According to recent research from Shanghai, People's Republic of China, "An RP-LC method has been developed for analysis of JS38 in the plasma, urine, bile, feces, and important tissues of rats. Chromatography was performed on a C-18 analytical column with 80:20 (%, v/v) ...
Scientists at RWTH Aachen University report research in chronic disease.
Nov 05, 2008 ... According to a study from Aachen, Germany, "Concepts of health management and improved quality of health care are of growing importance. In this context, the concept of empowerment is widely accepted in health-related disciplines." "The aim of the present study was to ...
Findings from St. Francis Hospital broaden understanding of chronic obstructive pulmonary disease.
Nov 05, 2008 ... According to a study from the United States, "In patients with chronic obstructive pulmonary disease, pulmonary rehabilitation significantly improves dyspnea, exercise capacity, quality of life, and health-resource utilization." "These benefits result from a combination of ...
Research from K.L. Rice and co-researchers in the area of chronic obstructive pulmonary disease published.
Nov 05, 2008 ... According to a study from the United States, "Sparse information exists about chronic obstructive pulmonary disease (COPD) outcomes among different ethnic groups. To determine whether the effect of tiotropium on COPD exacerbation differs between African Americans and Caucasians, we ...
Research from R. Casaburi and co-authors yields new data on chronic obstructive pulmonary disease.
Nov 05, 2008 ... According to recent research from the United States, "Pulmonary rehabilitation is widely accepted as effective therapy for patients with chronic obstructive pulmonary disease (COPD). This paper presents a brief (and somewhat subjective) history of pulmonary rehabilitation, and stresses the ...
Research on chronic obstructive pulmonary disease detailed by D.W. Mapel and co-authors.
Nov 05, 2008 ... "Lightweight portable oxygen systems are commonly preferred by patients over compressed-oxygen systems that use E-size cylinders. However, cost is often perceived as a barrier to the prescription of lightweight portable oxygen systems," scientists in the United States report (see also ...
Researchers at University of California, Medical Department target chronic obstructive pulmonary disease.
Nov 05, 2008 ... "Pulmonary rehabilitation has emerged as a standard of care for patients with chronic lung disease, based on a growing body of scientific evidence. Over recent decades, several organizations have championed pulmonary rehabilitation and developed comprehensive statements, practice ...
Findings in Churg-Strauss syndrome reported from University of Texas.
Nov 05, 2008 ... According to a study from the United States, " A 36-year-old white male with a history of allergic rhinitis and sinusitis presented to the emergency room with abdominal pain and diarrhea. Physical examination revealed fever, hypoxemia and a maculopapular rash." "Laboratory tests ...
Scientists at University of Adelaide publish new data on circadian rhythms.
Nov 05, 2008 ... "Few studies in non-mammalian vertebrates have examined how various effectors of the circadian system interact. To determine if the daily locomotor and behavioural thermoregulatory rhythms of Tiliqua rugosa are both controlled by the circadian system in different seasons, lizards were ...
New clinical pathology study results reported from Emory University.(Clinical report)
Nov 05, 2008 ... According to a study from the United States, "The purpose four study was to improve the quality of care in an emergency, department (ED) as measured by length stay (LOS), total turnaround time (TAT) for laboratory result reporting, and the blood culture contamination rate. Data were ...
Data on clinical pharmacy reported by researchers at Ghent University.(Report)
Nov 05, 2008 ... According to recent research from Ghent, Belgium, "The aim of this study was to evaluate the role and the impact of a clinical pharmacist as a member of a multidisciplinary pain team. Although physicians have a good knowledge of pharmacotherapy in the field of pain medication, pharmacy ...
New clinical trial research study findings recently were published by researchers at Kyung-Hee University, Medical Department.(Clinical report)
Nov 05, 2008 ... According to a study from Seoul, South Korea, "HT008-1 is one of the most effective multiherb mixtures that have neuroprotective effects in traditional Korean medicine. The purpose of this study was to conduct a clinical trial of the efficacy of HT008-1 on the neuropsychological ...
New findings in clinical trial research described from University of Lyon.
Nov 05, 2008 ... According to a study from Pavillon, France, "There is now strong evidence that probiotic bacteria can regulate inflammatory immune responses. Here, we analyzed whether oral supplementation with the probiotic bacterial strain Lactobacillus johnsonii (Lal) could interfere with skin immune ...
Reports by K. Steffen and co-researchers describe recent advances in clinical trial research.
Nov 05, 2008 ... "A set of exercises - the ''11'' - have been selected to prevent football injuries. The purpose of this cluster-randomized controlled trial was to investigate the effect of the ''11'' on injury risk in female youth football," scientists writing in the Scandinavian Journal of Medicine & ...
Reports outline clinical trial research study results from C. Laforce et al.(Clinical report)
Nov 05, 2008 ... According to recent research from the United States, "This study assessed the efficacy and safety of guaifenesin 600 mg and pseudoephedrine hydrochloride 60 mg extended-release bilayer tablets in providing relief of acute respiratory symptoms when used as an adjunct to antibiotics in ...
Research conducted at M. Henricson and co-researchers has updated our knowledge about clinical trial research.
Nov 05, 2008 ... In this recent study, researchers in Sweden conducted a study "To explore the effects of five-day tactile touch intervention on oxytocin in intensive care patients. The hypotheses were that tactile touch increases the levels of oxytocin after intervention and over a six-day period." ...
Research from University of Heidelberg has provided new information about clinical trial research.(Clinical report)
Nov 05, 2008 ... "The frequency of drug administration errors and incompatibilities between intravenous drugs before and after an intervention in an intensive care unit (ICU) is discussed. Critically ill adult patients with intoxications, multiorgan failure, and serious infections were included in a ...
Research on clinical trial research discussed by scientists at Florida International University.
Nov 05, 2008 ... According to recent research from the United States, "The randomized clinical trial (RCT) is a powerful experimental design that when properly executed produces generalizable results. Conducting a RCT becomes complex when technical skills are required." "Without requisite ...
Studies from National Institutes of Health yield new data on clinical trial research.
Nov 05, 2008 ... According to a study from the United States, "Interleukin-7 (IL-7) is a homeostatic cytokine for resting T cells with increasing serum and tissue levels during T cell depletion. In preclinical studies, IL-7 therapy exerts marked stimulating effects on T cell immune reconstitution in mice ...
Studies from University of Glasgow describe new findings in clinical trial research.(Clinical report)
Nov 05, 2008 ... According to a study from Scotland, "With surveys suggesting that exceeding guidelines for 'sensible' alcohol intake is commonplace, the health and social impact of modifying intake on a population level is potentially considerable. If public health interventions are to be successfully ...
Study data from Brown University provide new insights into clinical trial research.
Nov 05, 2008 ... "Many clinics and payers are beginning programs to collect and interpret outcomes related to quality of care and provider performance (ie, benchmarking). Outcomes assessment is commonly done using observational research designs, which makes it important for those involved in these ...
New findings from X.Y. Song and co-authors in the area of clostridium published.
Nov 05, 2008 ... According to recent research published in the journal Infection Control and Hospital Epidemiology, "Clostridium difficile-associated disease (CDAD) is responsible for increased morbidity and a substantial economic burden. Incidences of CDAD, including those with a severe course of illness, ...
New findings reported from A.C. Labbe and co-authors describe advances in clostridium.
Nov 05, 2008 ... "Since 2002, an epidemic of Clostridium difficile infections has occurred in southern Quebec, Canada. At Hopital Maisonneuve-Rosemont, Montreal, Quebec, Canada, the incidence of C. difficile infections increased from 11/1,000 admissions (1999 to 2002) to 27/1,000 admissions (2003 to ...
Report summarizes clostridium study findings from J. Lee and co-researchers.
Nov 05, 2008 ... "To understand the metabolic characteristics of Clostridium acetobutylicum and to examine the potential for enhanced butanol production, we reconstructed the genome-scale metabolic network from its annotated genomic sequence and analyzed strategies to improve its butanol production. The ...
Reports from M.F. Kurd et al highlight recent research in clostridium.(Report)
Nov 05, 2008 ... According to recent research from the United States, "Clostridium difficile-associated diarrhea is a recognized postoperative complication. However, the exact risk factors for this condition after total joint arthroplasty (TJA) remain unknown." "This case-controlled study ...
Research from University of Pennsylvania yields new findings on clubfoot.
Nov 05, 2008 ... According to a study from the United States, "Equinovarus of the foot is the most common lower extremity deformity following traumatic brain injury. We evaluated outcomes of the split anterior tibialis tendon transfer (SPLATT) for correction of equinovarus in 47 patients with hemiplegic ...
Findings from M. Durkin and co-researchers advance knowledge in coccidioidomycosis.
Nov 05, 2008 ... "We have previously shown antigenuria in patients with coccidioidomycosis through use of the Histoplasma antigen enzyme immunoassay (EIA), and now we have developed a specific Coccidioides antigen EIA. The Coccidioides EIA uses antibodies to Coccidioides galactomannan," scientists in the ...
Study findings from O. Noor et al provide new insights into coccidioidomycosis.
Nov 05, 2008 ... "A 42-year-old white male without prior skin disease presented 8 months ago with chest pain, fever, and coughing to his primary physician. At that point, he had no skin lesions," researchers in the United States report (see also Coccidioidomycosis). "The diagnosis was made by ...
New colloid science study findings recently were reported by researchers at Chiba University.
Nov 05, 2008 ... According to recent research from Chiba, Japan, "Morphology and surface states of colloidal probucol nanoparticles after dispersion of probucol/polyvinylpyrrolidone (PVP)/sodium dodecyl sulphate (SDS) ternary ground mixture into water were investigated by atomic force microscopy (AFM). The ...
Data from Macquarie University advance knowledge in coma.
Nov 05, 2008 ... According to a study from Australia, "Assessment of patients with mild traumatic brain injury (mTBI) is predominantly done using the Glasgow Coma Scale (GCS). While the GCS is universally accepted for assessment of severity of traumatic brain injury, it may not be appropriate to rely on ...
Research results from K.L. Griffith and co-authors update knowledge of coma.
Nov 05, 2008 ... "In Bacillus subtilis, the transcription factor ComA activates several biological processes in response to increasing population density. Extracellular peptide signaling is used to coordinate the activity of ComA with population density," scientists in the United States report (see also ...
Study data from Z.M. Kanaan and co-authors update knowledge of congenital anomalies.(Report)
Nov 05, 2008 ... According to a study from the United States, "Consanguinity is a recognized common practice among marriages in the Middle East. Many studies have suggested a strong association between first cousin marriages and the incidence of autosomal recessive diseases and congenital anomalies." ...
Investigators at Medical University of Graz have published new data on constipation.
Nov 05, 2008 ... "Opiates are indispensable for the treatment of moderate to severe pain. The gastrointestinal tract is one of the major victims of the undesired effects of opiates, because the enteric nervous system expresses all major subtypes of opioid receptors," scientists in Graz, Austria report (see ...
Research from S. Cowlam and co-authors yields new data on constipation.(Report)
Nov 05, 2008 ... According to recent research published in the journal Colorectal Disease, " Segmental colonic transit can be determined by performing regional counts of radio-opaque markers on an abdominal radiograph. It has been claimed that the pattern of markers can be used to characterize the type of ...
Recent findings from S. Motta and co-authors highlight research in cordectomy.(Clinical report)
Nov 05, 2008 ... "Vocal results after endoscopic cordectomy have not yet been well defined. The aim of this study was to assess the vocal function of patients who had undergone CO2 laser cordectomy," scientists writing in the Journal of Laryngology and Otology report (see also Cordectomy). ...
Findings from K.G. Moen and co-authors broaden understanding of craniocerebral trauma.(Report)
Nov 05, 2008 ... " This study compares injury severity and outcome of patients with severe head injury admitted directly to a neurosurgical department with those initially transferred to a local hospital. A retrospective analysis of all patients with severe head injury admitted to the Department of ...
Study results from A. Fabbri et al provide new insights into craniocerebral trauma.(Report)
Nov 05, 2008 ... According to recent research published in the Journal of Neurology Neurosurgery and Psychiatry, "The model of care for patients with mild-to-moderate head injury and CT-detected lesions that do not require an immediate intervention is a matter of debate. This study compared the effects on ...
Report summarizes critical care study findings from D. Belway and co-researchers.(Report)
Nov 05, 2008 ... According to recent research published in the Journal of Critical Care, "The aim of this study was to determine the association between transport intervals (includingtime from call to arrival of transport team at the sending hospital, time spent by the transport team in the sending ...
Reports summarize critical care study results from N.E. Jones and co-researchers.(Clinical report)
Nov 05, 2008 ... "The aim of this study was to determine factors that are associated with adherence to the Canadian nutrition support clinical practice guidelines (CPGs). We conducted a secondary analysis of data from a prospective observational cohort Study of nutrition support practices in 58 intensive ...
Research from R.P. Moreno and co-authors provides new data about critical care.
Nov 05, 2008 ... "The objective of the study was to develop a model for estimating patient 28-day in-hospital mortality using 2 different statistical approaches. The Study was designed to develop an outcome prediction model for 28-day in-hospital mortality using (a) logistic regression with random effects ...
Researchers at Vanderbilt University target critical care.
Nov 05, 2008 ... "We have shown previously that reduced integer heart rate variability (HRVi) predicts death in trauma patients. We hypothesized that heart rate multiscale entropy (MSE), a potential measurement of physiologic complexity, Would predict death more robustly than HRVi," investigators in the ...
New critical care medicine study findings have been reported by researchers at Korea University.
Nov 05, 2008 ... According to a study from Seoul, South Korea, "In a previous study, we reported that inotropic agents affect the hemodynamic energy, which can be measured using the energy equivalent pressure (EEP) and surplus hemodynamic energy (SHE). However, there has been no study about the effect of ...
New critical care medicine study findings recently were reported by researchers at Dalhousie University.
Nov 05, 2008 ... "Continuous positive airway pressure ventilation (CPAP) in appropriately selected patients with acute respiratory failure has been shown to reduce the need for tracheal intubation in hospital. Despite several case series, the effectiveness of out-of-hospital CPAP has not been rigorously ...
Data on Crohn disease published by researchers at Cleveland Clinic.
Nov 05, 2008 ... "Rectovaginal fistulas are dreaded complications of Crohn's disease. Accurate assessment is essential for planning management," scientists in the United States report (see also Crohn Disease). "Treatment options range from observation to medical therapeutics to the need for ...
Research from Autonomous University has provided new data on Crohn disease.
Nov 05, 2008 ... "Complex perianal fistulising disease is a distressing condition. In patients without Crohn's disease, surgery is the mainstay treatment but faecal incontinence and recurrence are high," scientists in Madrid, Spain report (see also Crohn Disease). "Infliximab is used in Crohn's ...
Research from University of Michigan reveals new findings on Crohn disease.
Nov 05, 2008 ... "Lymphocytic esophagitis (LE) is characterized by intraepithelial lymphocytes (IELs) and spongiosis, resembling contact dermatitis. LE has been defined as high numbers of IELs and no or rare granulocytes and was found in young patients and in association with Crohn disease (CD)," ...
Data on Cushing syndrome described by A. Tomova et al.(Report)
Nov 05, 2008 ... "This study was done to clarify the relation between melatonin secretion and the hypothalamic-pituitary-adrenal axis axis. In this clinical study using a follow-up approach, we investigated the circadian melatonin secretion and immune parameters of patients with corticotropin-dependent ...
Researchers from Beaumont Hospital report details of new studies and findings in the area of cutaneous lupus erythematosus.
Nov 05, 2008 ... According to a study from Dublin, Ireland, "Sun exposure of the skin, independent of dietary sources, may provide sufficient vitamin D in healthy individuals. A recent study of patients with cutaneous lupus erythematosus concluded that over 70% of them restrict their sun exposure." ...
Study findings from National Institutes of Health provide new insights into cyclic nucleotide research.
Nov 05, 2008 ... "The cyclic nucleotide phosphodiesterases (PDEs) are intracellur enzymes that catalyze the hydrolysis of 3,'5'-cyclic nucleotides, such as cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), to their sorresponding 5'-nuceotide monophosphates. These enzymes play ...
Report summarizes cyclooxygenase study findings from C. Jegerschold and co-researchers.
Nov 05, 2008 ... According to a study from Huddinge, Sweden, "Prostaglandins (PG) are bioactive lipids produced from arachidonic acid via the action of cyclooxygenases and terminal PG synthases. Microsomal prostaglandin E synthase 1 (MPGES1) constitutes an inducible glutathione-dependent integral membrane ...
Research from Hokuriku University has provided new data on cyclooxygenase.
Nov 05, 2008 ... "In the present study it was revealed that cannabidiolic acid ( CBDA) selectively inhibited cyclooxygenase (COX)-2 activity with an IC50 value (50% inhibition concentration) around 2 mc M, having 9-fold higher selectivity than COX-1 inhibition. In contrast, Delta(9)-tetrahydrocannabinolic ...