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<a href="http://www.highbeam.com/Biotech+Week/publications.aspx?date=200902" title="Articles and back issues from Biotech Week">Biotech Week articles</a>

Biotech Week back issues from February 2009:

Socially active and not easily stressed? You may not develop dementia.

Feb 04, 2009 ... A new study shows that people who are socially active and not easily stressed may be less likely to develop dementia. The research is published in the January 20, 2009, print issue of Neurology[R], the medical journal of the American Academy of Neurology (see also American Academy of ...

Study helps explain connection between sleep apnea, stroke and death.

Feb 04, 2009 ... BETHESDA, Md. (Jan. 6, 2009) - Obstructive sleep apnea decreases blood flow to the brain, elevates blood pressure within the brain and eventually harms the brain's ability to modulate these changes and prevent damage to itself, according to a new study published by The American ...

Salt reduction may offer cardioprotective effects beyond blood pressure reduction.

Feb 04, 2009 ... A study published in the February 2009 issue of the American Journal of Clinical Nutrition shows that salt reduction may offer cardioprotective effects beyond blood pressure reduction. The study was led by Kacie Dickinson of Flinders University, South Australia (see also American Society ...

BUSM researcher solves mystery of 9-month-old.

Feb 04, 2009 ... A researcher from Boston University School of Medicine (BUSM) has determined that a 9-month old infant who was admitted to a local Boston hospital with seizures and a bulging soft spot was actually suffering from rickets caused by vitamin D deficiency. This case study describing the ...

Burnham researchers discover 'on switch' for cell death signaling mechanism.

Feb 04, 2009 ... Scientists at Burnham Institute for Medical Research (Burnham) have determined the structure of the interactions between proteins that form the heart of the death inducing signaling complex (DISC), which is responsible for triggering apoptosis (programmed cell death) (see also Burnham ...

Hind wings help butterflies make swift turns to evade predators, study finds.

Feb 04, 2009 ... New tires allow race cars to take tight turns at high speeds. Hind wings give moths and butterflies similar advantages: They are not necessary for basic flight but help these creatures take tight turns to evade predators (see also Cornell University Communications). "To escape a ...

Scientists glean new insights into convection in planets and stars.

Feb 04, 2009 ... A new study by UCLA planetary scientists and their colleagues in Germany overturns a longstanding scientific tenet and provides new insights into how convection controls much of what we observe in planets and stars (see also University of California - Los Angeles). The research, ...

Research exposes the risk to infants from the chemicals used in liquid medicines.

Feb 04, 2009 ... A team of medical scientists from the University of Leicester has published research which looks into the harmful substances in liquid medicines that premature babies are being exposed to (see also University of Leicester). Research published (Jan 20) ahead of print in the Fetal ...

Growing years cut short for toddlers from poor families.(Report)

Feb 04, 2009 ... This release is available in French (see also University of Montreal). Montreal, January 19, 2008 u Continuous poverty during toddler years can curb the height of children by the time they reach kindergarten, even in industrialized countries, according to new research from the ...

Nuance Extends Offer to Acquire Zi Corporation.

Feb 04, 2009 ... Nuance Communications, Inc. (NASDAQ: NUAN) announced that it is extending its previously announced offer to purchase all of the outstanding common shares of Zi Corporation (NASDAQ: ZICA, TSX: ZIC) for US$0.40 per share in cash to 5:00 p.m. (Calgary time) on January 30, 2009, unless further ...

New data from I. Durursubasi et al illuminate research in abscess.

Feb 04, 2009 ... According to a study from Erzurum, Turkey, "A subperiostal abscess of the frontal bone as a complication of osteomyelitis, appearing as a puffy, indolent tumor of the forehead, was first described by Pott." "This less-common complication of is known as Pott's Puffy tumor. The ...

New achondroplasia study findings reported from Korea University.

Feb 04, 2009 ... According to a study from Seoul, South Korea, "Knowledge of bone age in achondroplasia is required for the prediction of adult height, timings of limb lengthening, and epiphysiodesis procedures. The purpose of this investigation was to determine the differences in skeletal age in ...

New findings from University of Aberdeen describe advances in acid reflux disease.

Feb 04, 2009 ... According to recent research from Scotland, " To determine the relative benefits and risks of laparoscopic fundoplication surgery as an alternative to long term drug treatment for chronic gastro- oesophageal reflux disease ( GORD). Multicentre, pragmatic randomised trial ( with parallel ...

Research from R.E. Delahoz and co-authors yields new data on acid reflux disease.(Report)

Feb 04, 2009 ... According to a study from the United States, "Gastroesophageal reflux disease is one of the most prevalent conditions among former World Trade Center (WTC) rescue and recovery workers. The reason for this proposed association with an inhalation injury is unclear." "In this ...

Researchers from University of South Australia publish findings in acid reflux disease.(Report)

Feb 04, 2009 ... According to recent research from Australia, "Gastroesophageal reflux disease is common in Western societies, although the prevalence of reflux symptoms in the community is not well described. In this study we determined the prevalence of symptoms of gastroesophageal reflux and other ...

New research on acute pancreatitis from S. Marusic and co-authors summarized.

Feb 04, 2009 ... According to a study from Zagreb, Croatia, "The aim of the study was to analyze the evidence-based use of antibiotic therapy in the treatment of acute pancreatitis and to identify factors influencing the introduction of antibiotic therapy in the setting of transitional country clinical ...

Reports from University of Bath describe recent advances in addiction medicine.

Feb 04, 2009 ... According to a study from Bath, the United Kingdom, "Family members of people with serious alcohol or drug problems are negatively affected by the behaviour and problems of their substance misusing relative. Conduct a feasibility study, testing whether a intervention successful in the UK, ...

Findings from L. Brunaud and co-authors broaden understanding of adenoma.

Feb 04, 2009 ... According to recent research from France, "Our aim was to determine the learning curve for robotic adrenalectomy and factors that influence operative time and cost. We prospectively evaluated of 100 consecutive patients who underwent robotic, unilateral, transperitoneal adrenalectomy." ...

New adenoma data have been reported by researchers at University of Amsterdam.(Report)

Feb 04, 2009 ... According to a study from Netherlands, "MYH-associated polyposis (MAP) is a disorder caused by a bi-allelic germline MYH mutation, characterized by multiple colorectal. adenomas. These adenomas typically harbor G:C → T:A transversions in the APC and K-ras genes caused by MYH ...

Reports outline adrenalectomy research from Catholic University.

Feb 04, 2009 ... According to recent research from Rome, Italy, "The choice in between the laparoscopic lateral transabdominal (LTA) or the posterior retroperitoneoscopic (PRA) approach for adrenalectomy is usually based on surgeon's preference, rather than on objective arguments. We compared the ...

New findings from Z.H. Wang and co-authors describe advances in adrenoleukodystrophy.

Feb 04, 2009 ... According to a study from Fuzhou, People's Republic of China, "Mutations in the ABCD1 gene lead to X-linked adrenoleukodystrophy, a neurodegenerative disorder. Hundreds of hereditary mutations of the gene have been reported in patients with X-linked adrenoleukodystrophy, but there have ...

Studies from University of Tubingen have provided new data on age-related maculopathy.(Report)

Feb 04, 2009 ... According to a study from Tubingen, Germany, " Patients with early age-related maculopathy ( ARM) do not necessarily show obvious morphological signs or functional impairment. Many have good visual acuity, yet complain of decreased visual performance." "The aim of this study was ...

University of Groningen publishes research in aggression.

Feb 04, 2009 ... "The present study aims at delineating violence from aggression, using genetically selected high (SAL, TA, NC900) and low (LAL, TNA NC100) aggressive mouse strains. Unlike aggression, violence lacks intrinsic control, environmental constraints as well as functional endpoints," scientists ...

Studies from S. Kumar and colleagues reveal new findings on aging.

Feb 04, 2009 ... According to recent research from India, "Dementia is one of the age related mental problems and characteristic symptom of various neurodegenerative diseases including Alzheimer's disease. This impairment probably is due to the vulnerability of the brain cells to increased oxidative stress ...

Research data from University of Michigan update understanding of alcoholism.(Report)

Feb 04, 2009 ... According to a study from the United States, "Neurocognitive deficits in chronic alcoholic men are well documented. Impairments include memory, visual-spatial processing, problem solving and executive function." "The cause of impairment could include direct effects of alcohol ...

Reports from University of Amsterdam highlight recent research in allergic contact dermatitis.

Feb 04, 2009 ... According to recent research from Netherlands, "To evaluate the anti-inflammatory efficacies of topical drugs, models of contact hypersensitivity (CHS) can be used, but the conventional murine models of CHS need revision in this respect. These models utilize sensitized mice to study ...

Findings from Baylor College of Medicine, College of Medicine advance knowledge in allergies.

Feb 04, 2009 ... According to a study from the United States, "Partial DiGeorge syndrome (pDGS) presents with thymic hypoplasia and a variable decrease in T-cell numbers. Although lymphocyte proliferation to mitogens is generally preserved, it is uncertain whether the development of specific cellular ...

New allergies research from K. Rossbach and co-researchers described.

Feb 04, 2009 ... "Effects of the histamine H-4 receptor antagonist JNJ 7777120 (1-[(5-chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine) were tested in two models of allergic contact dermatitis. Dermatitis was induced by 2,4-dinitrochlorobenzene and toluene-2,4-diisocyanate, which differ in their Th1-Th2 ...

Recent findings in allergies described by researchers from University of Verona.

Feb 04, 2009 ... "Chronic eczematous cheilitis comprises a heterogeneous group of disorders, the cause of which often remains obscure. Our object was to investigate the frequency of contact allergy in a cohort of patients with chronic eczematous cheilitis attending a tertiary referral clinic," ...

Report summarizes allergies study findings from N. Hiraki and co-researchers.(Clinical report)

Feb 04, 2009 ... In this recent report, researchers in Kitakyushu, Japan conducted a study "To investigate the relationships among nasal obstruction (NO), snoring, and excessive daytime sleepiness (EDS) in working people with or without allergic rhinitis (AR). Prospective study using questionnaires." ...

Research on allergies reported by scientists at University of Zurich.

Feb 04, 2009 ... "High dose bee venom exposure in beekeepers by natural bee stings represents a model to understand mechanisms of T cell tolerance to allergens in healthy individuals. Continuous exposure of nonallergic beekeepers to high doses of bee venom antigens induces diminished T cell-related ...

Scientists at University of Copenhagen report research in allergies.

Feb 04, 2009 ... "It is not known if reduced elicitation thresholds are evident among polysensitized individuals when using allergens to which the patients are already sensitized. Reduced elicitation thresholds may be an expression of increased reactivity in this patient group," scientists writing in the ...

Studies from Malmo University reveal new findings on allergies.

Feb 04, 2009 ... According to a study from Malmo, Sweden, "Disperse dyes (DDs) are the most common sensitizers among textile dyes, but there is little knowledge of the clinical relevance of positive patch test reactions. To investigate if patient-reported textile-related skin problems can be explained by ...

Studies from S. Koyanagi and co-researchers update current data on allergies.

Feb 04, 2009 ... According to a study from Kumamoto, Japan, "Hyposensitization, in which causative antigens of allergic diseases are injected, is the sole means of a radical cure for allergic diseases. Since the therapeutic allergens currently used are naturally extracted, producing preparations with a ...

Study results from University of Queensland in the area of allergies published.

Feb 04, 2009 ... "Bahia grass. Paspalum notatum, is a clinically important subtropical grass with a prolonged pollination season from spring to autumn. we aimed to clone and characterise the major Bahia grass pollen allergen, Pas n 1. Grass pollen-allergic patients presenting to a tertiary hospital allergy ...

Reports from T. Hasegawa and colleagues advance knowledge in allograft vasculopathy.

Feb 04, 2009 ... According to recent research from the United States, "Ecto-5'-nucleotidase (CD73) catalyzes the terminal phosphohydrolysis of 5'-adenosine monophosphate and is widely expressed on endothelial cells where it regulates barrier function. Because it is also expressed on lymphocytes, we ...

Data on alopecia reported by M. Eldomyati and co-researchers.

Feb 04, 2009 ... "Androgenetic alopecia is a common hair disorder, resulting from interplay of genetic, endocrine and aging factors. Meanwhile, it is unclear if an altered degree of proliferation or increased apoptosis could contribute to its pathogenesis," investigators in Egypt report (see also ...

Studies conducted at K.T. Tan et al on alopecia recently published.

Feb 04, 2009 ... "Frontal fibrosing alopecia is an uncommon condition characterized by progressive frontotemporal recession due to inflammatory destruction of hair follicles. Little is known about the natural history of this disease," scientists in Singapore, Singapore report (see also Alopecia). ...

Scientists at University of Alabama describe research in alpha 1-antitrypsin deficiency.

Feb 04, 2009 ... "The alpha coded testing (ACT) study offers free and confidential testing for alpha-1 antitrypsin deficiency (AATD) and includes surveys to provide data to study the psychosocial correlates of genetic testing. The purpose of the current study is to better understand reasons why some ...

New Alzheimer disease research from University of Kuopio outlined.

Feb 04, 2009 ... According to recent research from Kuopio, Finland, "Genetic and molecular studies have confirmed the central role of amyloid-beta production and fibrillation in the pathogenesis of Alzheimer's disease (AD). However, the pathological pathways from amyloid-beta peptide oligomerization to the ...

New Alzheimer disease study findings recently were published by H. Hanyu and co-researchers.

Feb 04, 2009 ... According to a study from Tokyo, Japan, " To determine the relationship of differing levels of education on regional cerebral blood flow (rCBF) in patients with Alzheimer's disease (AD). Fifty-three patients with AD followed-up for an average of 36 months were divided into the ...

New Alzheimer disease study findings recently were published by researchers at University of Kuopio.

Feb 04, 2009 ... According to recent research published in the journal Acta Neurologica Scandinavica, "Many studies have shown differences in carbonylation and nitration of individual proteins in brain and body fluids of Alzheimer's disease (AD) patients. Therefore, we wanted to examine whether total ...

Research from New York University yields new findings on Alzheimer disease.

Feb 04, 2009 ... " The objective of the study is to compare the diagnostic value of regional sampling of the cerebral metabolic rate of glucose metabolism (MRglc) using [18F]-fluoro-2-deoxyglucose ([18F]FDG)-positron emission tomography (PET) and amyloid-beta pathology using Pittsburgh Compound-B ...

Research from University of Yamanashi in the area of Alzheimer disease published.

Feb 04, 2009 ... According to recent research from Yamanashi, Japan, "Transthyretin (TTR) binds amyloid-beta (A beta) and prevents A beta fibril formation in vitro. It was reported that the lack of neurodegeneration in a transgenic mouse model of Alzheimer's disease (AD) (Tg2576 mouse) was associated with ...

Researchers at University of Genoa target Alzheimer disease.

Feb 04, 2009 ... " The purpose of the study is to evaluate the combined accuracy of episodic memory performance and F-18-FDG PET in identifying patients with amnestic mild cognitive impairment (aMCI) converting to Alzheimer's disease (AD), aMCI non-converters, and controls. Thirty-three patients with aMCI ...

Researchers from Bristol-Myers Squibb Company detail new studies and findings in the area of ambulatory surgery.

Feb 04, 2009 ... According to a study from Munich, Germany, "Paracetamol (acetaminophen) is one of the most widely used drugs for analgesia. We aimed to investigate the use of a ready-to-use intravenous (i.v.) paracetamol 1 g solution (Perfalgan((R))) as monotherapy or as adjunct therapy in patients ...

Research data from Fukui University update understanding of amyloidosis.

Feb 04, 2009 ... "A beta 2M (beta(2)-microglobulin-related) amyloidosis is a frequent and serious complication in patients on long-term dialysis. Partial unfolding of beta 2-m (beta(2)-microglobulin) may be essential to its assembly into A beta 2M amyloid fibrils in vivo," scientists writing in the ...

New amyotrophic lateral sclerosis study findings have been published by scientists at Cornell University, Medical Department.

Feb 04, 2009 ... According to recent research from the United States, "Our previous Studies implicated vitamin E deficiency as a risk factor For equine Motor neuron disease, a possible model of human amyotrophic lateral sclerosis, and showed direct effects of this deficiency on brain vascular endothelium ....

Researchers from Mayo Clinic provide details of new studies and findings in the area of anaphylactic shock.

Feb 04, 2009 ... "Reported incidences of anaphylaxis range from 3.2 to 20 per 100,000 population. The incidence and trend over time has meaningful public health implications but has not been well characterized because of a lack of a standard definition and deficiencies in reporting of events," scientists ...

Findings in anatomy reported from M.T. Sberna and co-researchers.

Feb 04, 2009 ... "To evaluate the use of peripheral quantitative computed tomography (pQCT) for qualitative and quantitative analysis of root canal anatomy and for assessing the extent of canal enlargement during root canal instrumentation. The volume variation achieved by S1 ProTaper instruments in the ...

Research on anatomy detailed by scientists at University of Zurich.

Feb 04, 2009 ... According to recent research published in the Journal of Anatomy, "We present reconstructions of petrosal anatomy based on high-resolution X-ray computed tomography scans for the fossil mammal Necrolestes and for the marsupial mole Notoryctes sp. Compared with other mammals, Necrolestes ...

Studies by R.A. Lazenby and co-authors describe new findings in anatomy.

Feb 04, 2009 ... "Variation in trabecular microarchitecture is widely accepted as being regulated by both functional (mechanical loading) and genetic parameters, although the relative influence of each is unclear. Studies reporting inter-site differences in trabecular morphology (volume, number and ...

Studies from C. Belentani and co-researchers in the area of anatomy published.

Feb 04, 2009 ... "The purpose of this cadaveric study was to describe the normal MR anatomy of the triceps brachii tendon (TBT) insertion, to correlate the findings with those seen in anatomic sections and histopathologic analysis, and to review triceps tendon injuries. Twelve cadaveric elbows were used ...

University of Louisville details research in anatomy.(Report)

Feb 04, 2009 ... "This study provides a model of the complex deltoid origin and end tendons, as a basis for further anatomical, biomechanical and clinical research. Although the deltoid is used in transpositions with upper limb paralysis, its detailed morphology and segmentation has not been object of much ...

Study results from Seoul National University in the area of anesthesia published.(Report)

Feb 04, 2009 ... According to a study from Seoul, South Korea, "We have conducted this study to investigate whether unilateral or bilateral spinal anesthesia with bupivacaine induces different sensitivity to intravenous (i.v.) midazolam for sedation. Forty-two patients undergoing various elective ...

New aneurysm research has been reported by J.F. Alen et al.(Report)

Feb 04, 2009 ... According to a study from Madrid, Spain, "In the past, several possible explanations for idiopathic subarachnoid hemorrhage (ISAH) have been proposed; however, neuroimaging studies have never provided conclusive data about the structural cause of the bleeding. The aim of this study is to ...

Researchers from University of Frankfurt detail new studies and findings in the area of aneurysm.

Feb 04, 2009 ... "To analyze the incidence and impact of an intracerebral hematoma (ICH) on treatment and outcome in patients with aneurysmal Subarachnoid hemorrhage. Data of 585 consecutive patients with subarachnoid hemorrhage from June 1999 to December 2005 were prospectively entered in a database," ...

New angiofibromas study findings reported from F. Tosun and co-authors.

Feb 04, 2009 ... According to recent research from Ankara, Turkey, "There are several studies addressing regression of residual nasopharyngeal angiofibroma after surgery, but spontaneous regression of this tumor has been reported in only 2 cases. We present a case of nasopharyngeal angiofibroma that has ...

New angiology research reported from University of Tampere, Medical Department.

Feb 04, 2009 ... "The present study was designed to investigate the effects of estrogen receptor 2 gene (ESR2) rs1256049 polymorphism to carotid artery intima-media thickness (CIMT), as part of the Cardiovascular Risk in Young Finns Study. The frequencies of ESR2 genotypes G/G, G/A, and A/A were 85.1%, ...

New angiology study findings have been published by scientists at University Hospital.

Feb 04, 2009 ... According to a study from Geneva, Switzerland, "A stenosis of the internal carotid artery may cause 10-20% of all ischemic strokes. Duplex ultrasound is the diagnostic cornerstone, and CT angiography or MR angiography may be used to confirm the severity of the stenosis or prior to ...

New angiology study results reported from J.P. Li et al.

Feb 04, 2009 ... According to recent research published in the Journal of Craniofacial Surgery, "The objective was to study the relationships among the optic nerve, posterior paranasal sinuses, and ophthalmic artery. The identification of reliable anatomic landmarks would provide an endoscopic anatomic ...

Reports outline angiology study findings from Cambridge University.

Feb 04, 2009 ... "Ionizing radiation exposure is an inherent component of endovascular surgery. As procedures become more complex, greater radiation exposure is incurred by both staff and patient," scientists in Cambridge, the United Kingdom report (see also Angiology). "Radiation doses during ...

Research data from A.J. Wagner and colleagues update understanding of angiology.

Feb 04, 2009 ... In this recently published article, scientists in the United States conducted a study "To evaluate the scapular free flap based on the angular artery in complex head and neck reconstruction. Case series. A tertiary referral center." "A series of 25 osteocutaneous scapular ...

Studies from S.W. Robertson and colleagues provide new data on angiology.

Feb 04, 2009 ... In this recent report, researchers in the United States conducted a study "To examine the effects of swallowing and side-to-side head turning on stents in the internal carotid artery. Seven patients (4 men; mean age 76.9 years) who underwent carotid artery stenting for the treatment of ...

Studies from F. Castriota and co-researchers in the area of angioplasty published.

Feb 04, 2009 ... In this recently published article, scientists in Cotignola, Italy conducted a study "To report a prospective feasibility study of Cutting Balloon angioplasty (CBA) applied in the predilation phase of carotid artery stenting (CAS) in highly calcified lesions. From January 2003 to February ...