Biotech Week back issues from April 2009:
Shrinking in hippocampus area of brain precedes Alzheimer's disease.
Apr 01, 2009 ... People who have lost brain cells in the hippocampus area of the brain are more likely to develop dementia, according to a study published in the March 17, 2009, print issue of Neurology[R], the medical journal of the American Academy of Neurology (see also American Academy of Neurology). ...
Journal Chest: March news briefs.(Report)
Apr 01, 2009 ... BLOOD CLOTS MORE LIKELY IN COPD PATIENTS WITH ACUTE EXACERBATIONS New research shows that one in four patients with chronic obstructive pulmonary disease (COPD) who are hospitalized with acute exacerbations may have pulmonary embolism (PE). Researchers from British Columbia analyzed data ...
Experienced air traffic controllers work smarter, not harder, making up for normal mental aging.
Apr 01, 2009 ... Older air traffic controllers can head off mid-air collisions at least as well as younger controllers, using experience to compensate for age-related declines in mental sharpness, a new study finds. The evidence that experience triumphs over the normal changes of aging could help to ...
Early results favorable for 5-day radiation treatment of early stage prostate cancer.
Apr 01, 2009 ... Preliminary results show that a shortened course of radiation therapy for prostate cancer called stereotactic body radiation therapy (SBRT) provides good PSA response for early-stage prostate cancer and has the same side effects as other treatments, according to a March 15 study in the ...
Guitarists' brains swing together.
Apr 01, 2009 ... When musicians play along together it isn't just their instruments that are in time u their brain waves are too. Research published in the online open access journal BMC Neuroscience shows how EEG readouts from pairs of guitarists become more synchronized, a finding with wider potential ...
Musicians have biological advantage in identifying emotion in sound.
Apr 01, 2009 ... Looking for a mate who in everyday conversation can pick up even your most subtle emotional cues? Find a musician, Northwestern University researchers suggest (see also Northwestern University). In a study in the latest issue of European Journal of Neuroscience, an ...
The 2 worlds of kids' morals.
Apr 01, 2009 ... Children's moral behavior and attitudes in the real world largely carry over to the virtual world of computers, the Internet, video games and cell phones. Interestingly, there are marked gender and race differences in the way children rate morally questionable virtual behaviors, according ...
New and unexpected mechanism identifies how the brain responds to stress.
Apr 01, 2009 ... Chronic stress takes a physical and emotional toll on our bodies and scientists are working on piecing together a medical puzzle to understand how we respond to stress at the cellular level in the brain. Being able to quickly and successfully respond to stress is essential for survival ...
Study gives more proof that intelligence is largely inherited.
Apr 01, 2009 ... They say a picture tells a thousand stories, but can it also tell how smart you are? Actually, say UCLA researchers, it can (see also University of California - Los Angeles). In a study published in the Journal of Neuroscience Feb. 18, UCLA neurology professor Paul Thompson and ...
'Mind-reading' experiment highlights how brain records memories.
Apr 01, 2009 ... It may be possible to "read" a person's memories just by looking at brain activity, according to research carried out by Wellcome Trust scientists. In a study published in the journal Current Biology, they show that our memories are recorded in regular patterns, a finding which challenges ...
Avalon Pharmaceuticals Receives Staff Determination Regarding Nasdaq Delisting.(Report)
Apr 01, 2009 ... Avalon Pharmaceuticals, Inc. (Nasdaq: AVRX), announced that on March 12, 2009, it received a Staff Determination letter from The Nasdaq Stock Market, LLC indicating that, as reported initially on November 25, 2008, Avalon fails to comply with Nasdaq Marketplace Rule 4450(a)(3) because the ...
Department of Justice Declines to Intervene in False Claims Act Lawsuits Against Gilead Sciences.
Apr 01, 2009 ... Gilead Sciences, Inc. (Nasdaq:GILD) announced that, after conducting an investigation, the United States Department of Justice (oDOJo) has notified the United States District Court for the Northern District of California oof its decision not to interveneo in a lawsuit filed by a former ...
Mortgage Fraud at an All-Time High According to Mortgage Asset Research Institute MARI[R].(Report)
Apr 01, 2009 ... Reported incidents of mortgage fraud in the U.S. are at an all-time high and increased by 26 percent from 2007 to 2008 according to a new report released by the Mortgage Asset Research Institute (MARI[R]), a LexisNexis[R] service. The 11th Periodic Mortgage Fraud Case Report to the ...
OPKO Health, Inc. Announces Hart-Scott-Rodino Filing for Purchase of Shares by Dr. Phillip Frost.(Report)
Apr 01, 2009 ... OPKO Health, Inc. (NYSE Alternext U.S.:OPK) announced Phillip Frost, M.D., Chairman and CEO of the Company, has filed a Notification and Report Form under the Hart-Scott-Rodino Antitrust Improvements Act of 1976 (the oHSRo Act), to allow him to purchase additional shares of OPKO HealthEs ...
Unexpected Side Effect: Makes You Happier.
Apr 01, 2009 ... In a study published in The Journals of Gerontology (Medical Sciences), researchers found that a brain fitness program measured initially for its impact on cognitive abilities in older adults also had a significant beneficial impact on symptoms of depression (see also Posit Science). ...
New Report Further Demonstrates Ultra-Glo[TM] Luciferase is Less Susceptible to Compound Interference.
Apr 01, 2009 ... Research results just published in the Journal of Medicinal Chemistry demonstrate the superior performance of Promega Ultra-GloO Luciferase. The research, conducted by the NIH Chemical Genomics Center (NCGC), describes Ultra-Glo recombinant luciferase as approximately 90% less susceptible ...
Stanford Study Improves Insights Into Parkinson's Disease and Possible Treatments.
Apr 01, 2009 ... About the only thing doctors have understood about deep-brain stimulation, which is widely used to treat ParkinsonEs disease symptoms, is that somehow it works for many patients. In a new study that will be published March 19 in the online journal Science Express, Stanford University ...
Research from University of Ioannina broadens understanding of abdominal aortic aneurysm.(Report)
Apr 01, 2009 ... According to recent research from Ioannina, Greece, "Endovascular repair of abdominal aortic aneurysm (EVAR) requires the patient's extended exposure to X-rays, before, during, and after the intervention. The aim of this study was to determine the radiation exposure of patients undergoing ...
Researchers at University of Limerick target abdominal aortic aneurysm.(Report)
Apr 01, 2009 ... "Abdominal aortic aneurysm (AAA) rupture is believed to occur when the local mechanical stress exceeds the local mechanical strength of the wall tissue. On the basis of this hypothesis, the knowledge of the stress acting on the wall of an unruptured aneurysm could be useful in determining ...
Data on acid reflux disease detailed by researchers at Charite University.
Apr 01, 2009 ... According to a study from Berlin, Germany, "Gastro-oesophageal reflux disease (GERD) is a common disorder associated with substantial reductions in health-related quality of life (HRQL). To describe patterns of change in HRQL during 5 years of follow-up in a large population of GERD ...
Studies from Ankara University provide new data on acid reflux disease.
Apr 01, 2009 ... In this recent report, researchers in Ankara, Turkey conducted a study "To determine the clinical value of pharyngeal pH monitoring for the diagnosis of laryngopharyngeal reflux (LPR) by using a double-probe, triple-sensor catheter in patients with symptoms of LPR. Prospective review of pH ...
Studies from S.H. Kim and colleagues reveal new findings on acute hepatotoxicity.
Apr 01, 2009 ... According to recent research published in the Journal of Pharmacological Sciences, "The hepatoprotective effects of ACTIValoe (R) N-931 complex, a mixture of Aloe vera and Silybum marianum, against acute and chronic carbon tetrachloride (CCl4)-induced liver injuries were investigated ....
Research from University of California yields new data on acute pancreatitis.
Apr 01, 2009 ... According to a study from the United States, "Mechanisms of acinar cell death in pancreatitis are poorly understood. Cytochrome c release is a central event in apoptosis in pancreatitis." "Here, we assessed the regulation of pancreatic cytochrome c release by Ca2+, mitochondrial ...
Research reports from A.J.B. Wall and co-authors provide new insights into addiction medicine.
Apr 01, 2009 ... "WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT center dot The Summary of Product Characteristics (SPC) is a legal document that gives healthcare providers information concerning each specific drug, including advice on the management of overdose. center dot Clinical outcomes after drug overdose ...
Studies in the area of addiction medicine reported from M.L. Pelchat and co-researchers.
Apr 01, 2009 ... "Most of the evidence for or against food addiction in humans focuses on similarities between food craving and drug craving. There are numerous parallels in neuroanatomy, neurochemistry, and learning," scientists in the United States report (see also Addiction Medicine). ...
Researchers from University of Texas report details of new studies and findings in the area of adenoma.
Apr 01, 2009 ... "A uniform and reliable description of the exact locations of adenomatous parathyroid glands is necessary for accurate communications between surgeons and other specialists. We developed a nomenclature that provides a precise means of communicating the most frequently encountered ...
Research from University of Cambridge provide new insights into adolescence.
Apr 01, 2009 ... "This article investigates the life success at ages 32 and 48 of four categories of males: nonoffenders, adolescence-limited offenders (convicted only at ages 10-20), late-onset offenders (convicted only at ages 21-50), and persistent offenders (convicted at both ages 10-20 and 21-50). In ...
Reports on adult onset still disease findings from Hanyang University provide new insights.
Apr 01, 2009 ... According to recent research from Seoul, South Korea, "Fey receptors (Fc gamma R) have important functions in the regulation of immune response and clearance of immune complex. High levels of immunoglobulins have been observed in patients with the active stage of adult onset Still's ...
New adverse drug reactions data have been reported by scientists at University of Ottawa.(Clinical report)
Apr 01, 2009 ... "Adverse events (AEs) are patient injuries caused by medical care. Previous studies have reported increased mortality rates and prolonged hospital length of stay in patients having an AE," scientists writing in the journal BMC Health Services Research report (see also Adverse Drug ...
New findings from C. Pedros and co-authors in the area of adverse drug reactions published.(Report)
Apr 01, 2009 ... According to a study from Barcelona, Spain, "Spontaneous reporting of adverse drug reactions (ADRs) in hospitals is scarce and several obstacles to such reporting have been identified previously. To assess the effectiveness of a multifaceted intervention based on healthcare management ...
Research on adverse drug reactions published by I.A. Juster et al.
Apr 01, 2009 ... "Disease management (DM) programs claim to achieve cost savings by reducing clinical adverse events. While measuring changes in adverse events is straightforward, plausibly demonstrating savings has been contentious, especially absent an external comparison population," researchers in the ...
Studies in the area of adverse drug reactions reported from S. Yokohama and co-researchers.
Apr 01, 2009 ... "Percutaneous endoscopic gastrostomy (PEG) has become established as a useful enteral nutrition technique. Although various adverse events related to PEG are known, few reports have described Clostridium difficile-associated enteric disease (CDED) after PEG," scientists in Asahikawa, Japan ...
Recent studies by K. Neelam and co-authors add new data to age-related maculopathy findings.
Apr 01, 2009 ... In this recent report, researchers in Waterford, Ireland conducted a study "To compare clinical age-related maculopathy (ARM) grading using slit-lamp biomicroscopy (SLB) versus photographic grading of stereoscopically captured fundus photographs (FP) using a high-resolution fundus camera ....
Research on aggression published by scientists at Northern Illinois University.(Report)
Apr 01, 2009 ... "Aggressive responding following benzodiazepine ingestion has been recorded in both experimental and client populations, however, the mechanism responsible for this outcome is unclear. The goal of this study was to identify an affective concomitant linked to diazepam-induced aggression ...
Recent studies by E. Carletti and co-authors add new data to aging findings.
Apr 01, 2009 ... "Human butyrylcholinesterase (hBChE) hydrolyzes or scavenges a wide range of toxic esters, including heroin, cocaine, carbamate pesticides, organophosphorus pesticides, and nerve agents. Organophosphates (OPs) exert their acute toxicity through inhibition of acetylcholinesterase (AChE) by ...
Research from University of Tokyo provides new data about aging.
Apr 01, 2009 ... According to recent research from Hongo, Japan, "The intracellular accumulation of unfolded or misfolded proteins is believed to contribute to aging and age-related neurodegenerative diseases. However, the links between age-dependent proteotoxicity and cellular protein degradation systems ...
Research from University of Trieste in the area of aging published.
Apr 01, 2009 ... In this recent report published in the Journal of Adhesive Dentistry, researchers in Trieste, Italy conducted a study "To evaluate microtensile bond strength and interfacial nanoleakage expression of adhesive interfaces created by XP-Bond on human deproteinized dentin immediately after ...
Research on aging discussed by scientists at University of Munster.(Report)
Apr 01, 2009 ... According to recent research from Munster, Germany, "Few studies have examined the effect of age on skilled perception. The purpose of this study was to determine whether the perceptual-motor abilities of highly skilled performers in dynamic, time-constrained sports exhibited the same ...
Researchers at Boston University target aging.(Report)
Apr 01, 2009 ... "In this study, a reverse-engineering strategy was used to infer and analyze the structure and function of an aging and glucose repressed gene regulatory network in the budding yeast Saccharomyces cerevisiae. The method uses transcriptional perturbations to model the functional ...
Scientists at University of Jaen publish research in aging.(Report)
Apr 01, 2009 ... According to a study from Jaen, Spain, "Inhibition is considered to have an important role in memory retrieval. However, many experimental results suggest that its efficiency declines with aging." "In this study, the authors tested this hypothesis by using the ...
Study findings from University of Waterloo broaden understanding of aging.(Report)
Apr 01, 2009 ... In this recent report published in the journal Psychosomatic Medicine, researchers in Waterloo, Canada conducted a study "To assess the robustness of the association between intelligence quotient (IQ) and mortality in older adults and to examine whether or not the association can be ...
Findings in alcoholism reported from Linkoping University.(Report)
Apr 01, 2009 ... "Moderate alcohol consumption has been reported to be inversely associated with cardiovascular disease and total mortality. The importance of non-alcoholic fatty liver disease (NAFLD) is increasing and many NAFLD patients suffer from cardiovascular disease," scientists in Sweden report ...
New allergies study findings reported from University of Wisconsin, Medical Department.(Report)
Apr 01, 2009 ... According to recent research from the United States, "The primary function of IL-7 is to promote maturation and survival of T cells. Through microarray expression analysis, we previously observed that human blood eosinophils express mRNA for IL-7R alpha (CD127) and its common gamma chain ...
Recent findings in allergies described by researchers from University of New Mexico, Medical Department.(Report)
Apr 01, 2009 ... According to recent research from the United States, "Adiponectin is associated with asthma. The direction of this association is no( known in humans." "In mice, this association is bidirectional: allergen inhalation affects serum adiponcetin, and exogenous adiponcetin ...
Reports outline allergies study findings from T.A. Doherty and colleagues.
Apr 01, 2009 ... According to recent research from the United States, "Doherty TA, Soroosh P, Broide DH, Croft M. CD4+ cells are required for chronic eosinophilic lung inflammation but not airway remodeling. Am J Physiol Lung Cell Mol Physiol 296: L229-L235, 2009." "First published December 5, ...
Researchers at College of Medicine release new data on allergies.
Apr 01, 2009 ... According to recent research from the United States, "Microbial survival in a host is usually dependent on the ability of a pathogen to undergo changes that promote escape from host defense mechanisms. The human-pathogenic fungus Cryptococcus neoformans undergoes phenotypic switching in ...
Findings from Sichuan University broaden understanding of altitude sickness.
Apr 01, 2009 ... "Acute mountain sickness (AMS) is usually seen in unacclimatized individuals ascending to a high altitude within a short period of time. Severe cases may be complicated with multiorgan dysfunction syndrome (MODS), which results in very high mortality," researchers in Chengdu, People's ...
Data on Alzheimer disease detailed by R.L. Frozza and co-authors.
Apr 01, 2009 ... "Accumulation of the neurotoxic amyloid beta-peptide (A beta) in the brain is a hallmark of Alzheimer's disease (AD). Several synthetic A beta peptides have been used to study the mechanisms of toxicity," scientists writing in the journal Neurochemical Research report (see also Alzheimer ...
Findings from Complutense University provide new insights into Alzheimer disease.
Apr 01, 2009 ... "Matrix metalloproteinases (MMPs) and oxidative stress have been implicated in neurological diseases such as Alzheimer's disease (AD). Plasma MMP-2 and MMP-9 activities were assessed in Mild Cognitive Impairment (MCI) and AD subjects compared with aged-matched controls, and subsequently ...
Reports outline Alzheimer disease research from National Taipei University of Technology.(Report)
Apr 01, 2009 ... According to recent research from Taipei, Taiwan, "The amyloid beta-peptides (A beta s) are the main protein components of amyloid deposits in Alzheimer's disease (AD). Detailed knowledge of the structure and assembly dynamics of A beta is important for the development of properly targeted ...
Research from Q. Liu and co-researchers yields new findings on Alzheimer disease.
Apr 01, 2009 ... According to recent research from the United States, "Nicotinic acetylcholine receptors (nAChRs) containing alpha 7 subunits are thought to assemble as homomers. alpha 7-nAChR function has been implicated in learning and memory, and alterations of alpha 7-nAChR have been found in patients ...
Researchers' work from University of Nevada focuses on Alzheimer disease.
Apr 01, 2009 ... "Oxidative stress has been suggested to contribute to neuronal apoptosis associated with Alzheimer's disease (AD). Copper may participate in oxidative stress through redox-cycling between its +2 and +1 oxidation states to generate reactive oxygen species (ROS)," scientists writing in the ...
Scientists at Technical University target Alzheimer disease.(Report)
Apr 01, 2009 ... "Basal forebrain cholinergic neurons (BFCNs) degenerate in aging and Alzheimer's disease. It has been proposed that estrogen can affect the survival and function of BFCNs," investigators in the United States report (see also Alzheimer Disease). "This study characterized primary ...
Study data from University of Melbourne provide new insights into Alzheimer disease.
Apr 01, 2009 ... According to recent research from Melbourne, Australia, "Cognitive decline in Alzheimer's disease (AD) involves pathological accumulation of synaptotoxic amyloid-beta (A beta) oligomers and hyperphosphorylated tau. Because recent evidence indicates that glycogen synthase kinase 3 beta ...
Recent studies by R.B. Kucumen and co-authors add new data to ametropia findings.
Apr 01, 2009 ... According to a study from Istanbul, Turkey, "The authors describe a technique of laser in situ keratomileusis (LASIK) for the management of postkeratoplasty ametropia using a femtosecond laser for flap creation. The first step was the placement of a disposable suction fixation ring to ...
Research by R.I. Westphalen and colleagues in amnesia provides new insights.(Report)
Apr 01, 2009 ... According to recent research from the United States, "Inhaled anaesthetics (IAs) produce multiple dose-dependent behavioural effects including amnesia, hypnosis, and immobility in response to painful stimuli that are mediated by distinct anatomical, cellular, and molecular mechanisms ....
Research conducted at Columbia University has provided new information about amyotrophic lateral sclerosis.
Apr 01, 2009 ... "Amyotrophic lateral sclerosis (ALS) remains a clinical diagnosis without definable biomarkers," scientists writing in the journal Muscle & Nerve report (see also Amyotrophic Lateral Sclerosis). "The pathomechanism of motor neuron degeneration in ALS has yet to be elucidated ....
Researchers at Tor Vergata University publish new data on amyotrophic lateral sclerosis.(Report)
Apr 01, 2009 ... According to recent research published in the journal Experimental Neurology, "Cortical hyperexcitability has been observed in Amyotrophic Lateral Sclerosis (ALS) patients. Familial ALS accounts for 10% of all cases and mutations of the Cu,Zn superoxide dismutase (SOD1) gene have been ...
Study findings from Albany Medical College, Medical College provide new insights into analgesics.
Apr 01, 2009 ... "Despite nearing the end of the decade of pain research, the analgesic mechanisms of one of the most widely used and popular analgesics remains uncertain. Acetaminophen (APAP) (paracetamol [PARA]) has been used clinically for over a half of a century and although clinicians seem to be ...
New anatomy study findings recently were reported by researchers at Hebei Medical University.
Apr 01, 2009 ... In this recent article published in the World Journal of Gastroenterology, scientists in Shijiazhuang, People's Republic of China conducted a study "To explore the role of color Doppler flow imaging (CDFI) in visualization of spleen vessels and to define its value for spleen ...
Findings from R. Nayyar and co-authors provide new insights into anesthesia.
Apr 01, 2009 ... In this recent article published in the Journal of Endourology, scientists in New Delhi, India conducted a study "To evaluate the feasibility and safety of two concomitant robot-assisted procedures in the same patient in one anesthesia setting. Data were reviewed for 15 patients for whom ...
New anesthesia research from M. Messina and colleagues discussed.(Clinical report)
Apr 01, 2009 ... According to recent research published in the journal Minerva Anestesiologica, "The authors performed a study to evaluate if the onset time, duration of sensory block, and quality of postoperative analgesia in Superficial cervical plexus anesthesia with 0.5% levobupivacaine (1 mg/kg) was ...
Reports outline anesthesia research from Lapeyronie University.
Apr 01, 2009 ... According to recent research published in the Canadian Journal of Anaesthesia - Journal Canadien D Anesthesie, "Septorhinoplasty is a traumatic procedure that is associated with epistaxis and postoperative pain. The primary objective of this randomized double-blind controlled trial was to ...
Research from D. Faraoni and co-researchers in the area of anesthesia published.(Clinical report)
Apr 01, 2009 ... "Ketamine 0.15-1 mg kg(-1) decreases postoperative morphine consumption, but 0.5 mg kg(-1) is associated with an increase in the bispectral index (BIS) values that can lead to an overdose of hypnotic agents. The purpose of our investigation was to study the effect of ketamine 0.2 mg kg(-1) ...
Research from M. Dalsasso and co-researchers yields new findings on anesthesia.
Apr 01, 2009 ... "Education is the core activity of academic anaesthesia departments. One of the main difficulties appears to be the development of realistic high-quality 'training' practices that are safe For patients," scientists in Padua, Italy report (see also Anesthesia). "The aim of this ...