Blood Weekly back issues from September 2008:
New acute myeloid leukemia study findings have been reported from J. Sierra et al.(Clinical report)
Sep 04, 2008 ... "Patients with acute myeloid leukemia (AML) are often neutropenic as a result of their disease. Furthermore, these patients typically experience profound neutropenia following induction and/or consolidation chemotherapy and this may result in serious, potentially life-threatening, ...
New angiolymphoid hyperplasia research from M.K. Varshney et al outlined.
Sep 04, 2008 ... "Kimura's disease is a rare, chronic inflammatory disorder, presenting usually as head and neck swellings and regional cervical lymphadenopathy," researchers in New Delhi, India report (see also Angiolymphoid Hyperplasia). "The disease is more often described from oriental ...
Investigators at Thomas Jefferson University target appendicitis.
Sep 04, 2008 ... In this recent report, researchers in the United States conducted a study "To assess computed tomographic (CT) signs that have been described in published studies for the diagnosis of appendicitis to identify independent findings that predict appendicitis. A retrospective database search ...
New blood components findings from Juntendo University, Medical Department described.
Sep 04, 2008 ... According to a study from Hongo, Japan, "ABO-incompatible blood transfusions attributable to inadequate identification (ID) of the patient or the blood unit are among the most serious of transfusion hazards. It has been unclear whether a computer-assisted transfusion management system ...
Research on blood components published by M. Ghio et al.
Sep 04, 2008 ... According to a study from Genoa, Italy, "Over the past decades, the weight of the published literature demonstrates that blood transfusions can induce clinically significant immunosuppression in recipients. Several studies showed significant improved clinical outcomes in the patients ...
New enzyme research findings from Medical University of Graz described.(Report)
Sep 04, 2008 ... According to recent research from Graz, Austria, "Apheresis technology has made tremendous progress up to the development of automated blood component collection, which offers increased efficiency in donor blood use, but the concern about the contact of donor blood with artificial surfaces ...
Research from K.J. Ho et al broadens understanding of hypotension.
Sep 04, 2008 ... "Compared with standard donors, kidneys recovered from donors after cardiac death (DCD) exhibit higher rates of delayed graft function (DGF), and DCD livers demonstrate higher rates of biliary ischemia, graft loss, and worse patient survival. Current practice limits the use of these organs ...
Research from University of Miami has provided new information about life sciences.
Sep 04, 2008 ... "One of the most complicated issues that surgeons face, in the care of burn patients, is infection," scientists in the United States report (see also Life Sciences). "This includes both superficial and systemic infections. Systemic infection is the leading cause of death in this ...
Studies from University of the West Indies describe new findings in life sciences.
Sep 04, 2008 ... According to recent research from Kingston, Jamaica, "The investigation of presumed neutropenia places a. burden on the health services, especially those of developing countries, including Jamaica. This may be because the normal ranges used in the laboratory are based on the values ...
Studies from Queen Elizabeth Hospital reveal new findings on lymphoma.
Sep 04, 2008 ... "IgG4-related sclerosing disease is a recently recognized inflammatory lesion frequently involving pancreas, submandibular gland, lacrimal gland, and lymph node. We report 3 cases of ocular adnexal lymphoma arising in IgG4-related chronic sclerosing dacryoadenitis, a phenomenon that has ...
New lymphopenia study results reported from Chinese University of Hong Kong.
Sep 04, 2008 ... "Severe Acute Respiratory Syndrome (SARS) outbreak in 2002-03 caused morbidity in over 8000 individuals and mortality in 744 in 29 countries. Lymphopenia along with neutrophilia was a feature of SARS, as it is in respiratory syncytial virus (RSV) and Ebola infections, to name a few," ...
Studies from University of Toronto provide new data on malaria.(Report)
Sep 04, 2008 ... "Although acute lung injury (ALI) is a common complication of severe malaria, little is known about the underlying molecular basis of lung dysfunction. Animal models have provided powerful insights into the pathogenesis of severe malaria syndromes such as cerebral malaria (CM); however, no ...
Research results from Karolinska University update understanding of myelodysplastic syndrome.
Sep 04, 2008 ... " To assess the effect of erythropoietin (EPO) plus granulocyte-colony stimulating factor (G-CSF) treatment on survival and leukemic transformation in myelodysplastic syndrome (MDS). Patients and Methods We compared the long-term outcome of patients with MDS treated with EPO plus G-CSF (n ...
Research from P.A. Chandra et al broadens understanding of neutropenia.
Sep 04, 2008 ... "Felty's syndrome is regarded as a severe variant of rheumatoid arthritis (RA) that develops in less than 1 % of patients with RA. It consists of a triad of RA, splenomegaly, and leukopenia, which tends to develop after a long course of RA," scientists in the United States report (see also ...
New Data Support Earlier Suggested Guidance for Levels of Cell-Mediated Immunity in Pediatric Liver Transplant Patients.
Sep 04, 2008 ... Israeli et al.,* in an article just published in the peer-reviewed journal Liver Transplantation, have further developed our understanding of the clinical potential of monitoring cell- mediated immunity in pediatric liver-transplant patients post-transplantation (see also Pediatrics). ...
Vermillion Announces Publication of Data Supporting Its Peripheral Artery Disease Diagnostic Test Program.
Sep 04, 2008 ... Vermillion, Inc. (NASDAQ:VRML), a molecular diagnostics company, announced the publication of data supporting its peripheral artery disease (PAD) diagnostic program. The results were published in the August, 2008 issue of the peer-reviewed journal, Vascular Medicine. The study was led by ...
Studies from T. Utsumi et al provide new data on sepsis.
Sep 04, 2008 ... According to recent research from Yokohama, Japan, "The mechanism of pseudoaneurysm formation caused by prolonged sepsis is thought to be related to the vascular endothelium being directly invaded and broken by bacteria. Moreover, matrix metalloproteinases (MMPs) which are up-regulated by ...
Researchers from Duke University describe findings in sickle cell anemia.(Report)
Sep 04, 2008 ... According to recent research published in the American Journal of Obstetrics and Gynecology, "The purpose of this study was to identify morbidity that is associated with sickle cell disease (SCD) in pregnancy. The Nationwide Inpatient Sample from the Healthcare Cost and Utilization Project ...
New spinal cord injury data have been reported by scientists at Virginia Commonwealth University.
Sep 04, 2008 ... "Few therapies have consistently demonstrated effectiveness in preserving 0, delivery after spinal cord injury (SCI). Perfluorocarbons (PFCs) offer great promise to carry and deliver Q, more efficiently than conventional measures," researchers in the United States report (see also Spinal ...
Recent findings in stomach cancer described by H. Kim and colleagues.
Sep 04, 2008 ... "The precise localization of target lymph nodes during laparoscopic biopsy can often be technically challenging. The purpose of this series was to report 2 patients who successfully underwent laparoscopic para-aortic lymph node sampling with the assistance of laparoscopic ultrasonography ...
New Data Support Role for Monitoring of Cell-Mediated Immunity in Adult Patients Following Renal Transplantation.
Sep 04, 2008 ... A recently published article by Sanchez-Velasco et al.* in Clinical Transplantation has expanded our understanding of the clinical potential of monitoring cell-mediated immunity in adult patients at risk for organ rejection or infection subsequent to kidney transplantation (see also ...
New findings from Northwestern University describe advances in cancer prognosis.
Sep 04, 2008 ... New investigation results, 'Perinucleolar compartment prevalence is a phenotypic pancancer marker of malignancy,' are detailed in a study published in Cancer. According to recent research published in the journal Cancer, "The perinucleolar compartment (PNC) is a subnuclear structure ...
Report summarizes enzyme research study findings from Baylor College of Medicine, Department of Pediatric Gastroenterology.(Report)
Sep 04, 2008 ... Data detailed in 'Pathophysiology of LPS-induced gastrointestinal injury in the rat: role of secretory phospholipase A2' have been presented. "A hydrophobic layer of phosphatidylcholine (PC) overlies and protects the surface of the gastrointestinal (GI) tract, contributing to barrier ...
Research results from Shiraz University of Medical Sciences, Department of Pediatrics update understanding of life sciences.
Sep 04, 2008 ... Current study results from the report, 'Visceral leishmanisis in paediatrics: a study of 367 cases in southwest Iran,' have been published. According to recent research from Iran, "Kala-azar (visceral leishmaniasis [VL]) is endemic in southern Iran. We retrospectively evaluated 367 infants ...
Data from Wonkwang University, Department of Internal Medicine provide new insights into lung cancer therapy.(Report)
Sep 04, 2008 ... Research findings, 'Combination treatment with arsenic trioxide and sulindac enhances apoptotic cell death in lung cancer cells via activation of oxidative stress and mitogen-activated protein kinases,' are discussed in a new report. "Arsenic trioxide (As2O3) has been introduced to the ...
Study data from Columbia University update knowledge of neutropenia therapy.(Report)
Sep 04, 2008 ... New research, 'Neutropenia in 6 ethnic groups from the Caribbean and the U.S,' is the subject of a report. "Low white blood cell counts (WBC) or absolute neutrophil counts (ANC) may delay or prevent the completion of appropriate chemotherapy, especially among women receiving adjuvant ...
Harvard University publishes research in sepsis.
Sep 04, 2008 ... Investigators publish new data in the report 'A3 and P2Y2 receptors control the recruitment of neutrophils to the lungs in a mouse model of sepsis.' According to a study from the United States, "We have recently shown that A3 adenosine receptors and P2Y2 purinergic receptors play an ...
Researchers from University of Texas describe findings in acute myeloid leukemia.
Sep 04, 2008 ... According to a study from the United States, "Acute myeloid leukemia with t(8;21)(q22;q22) is a distinct type of leukemia considered to have a favorable prognosis. However, some patients rapidly succumb to disease despite chemotherapy." "We studied 56 patients with acute myeloid ...
Research from M. Ouaissi and co-researchers provides new data on adenocarcinoma.
Sep 04, 2008 ... According to a study from Marseille, France, "Alterations in HDACs gene expression have been reported in a number of human cancers. No information is available concerning the status of HDACs in pancreatic cancer tumors." "The aim of the present study was to evaluate the ...
New adverse drug reactions study findings recently were published by researchers at St. Thomas' Hospital, Emergency Department.(Clinical report)
Sep 04, 2008 ... Researchers in London, the United Kingdom conducted a study "To evaluate the use of intravenous ketamine for procedural sedation in adults attending the emergency department. A prospective study was performed over a 2-year period in 92 patients who received intravenous ketamine for ...
Study results from University of Sydney in the area of aging published.
Sep 04, 2008 ... "Morphological changes in the hepatic sinusoid with old age are increasingly recognized. These include thickening and defenestration of the liver sinusoidal endothelial cell, sporadic deposition of collagen and basal lamina in the extracellular space of Disse, and increased numbers of fat ...
New aneurysm research reported from M. Lacombe and co-authors.(Report)
Sep 04, 2008 ... "The purpose of this study was to report our experience of surgical treatment of aortoiliac aneurysms in kidney transplant patients, to describe technical problems of this surgery, to evaluate its long-term outcome, and to discuss the place of endovascular repair. Eighteen patients who had ...
New aneurysm research reported from W.C. Sternbergh and co-authors.(Clinical report)
Sep 04, 2008 ... "Recommended postoperative surveillance after endovascular aneurysm repair (EVAR) includes serial contrast-enhanced CT scans. The cumulative deleterious effect on renal function, radiation exposure, and significant cost of this surveillance regimen are all problematic," researchers in the ...
Research from Karolinska University provides new data on aneurysm.(Clinical report)
Sep 04, 2008 ... According to recent research from Stockholm, Sweden, "The aim of this study was to analyze the clinical results of Guglielmi detachable bare coil (GDC) embolization of intradural saccular aneurysms (AAs) at a single center and to relate the morphological results at various time points to ...
Research from Yonsei University reveals new findings on aneurysm.
Sep 04, 2008 ... According to recent research published in the Journal of Neuroimaging, "We report a case of a 70-year-old man harboring a wide-necked thrombosed giant aneurysm of the left middle cerebral artery (MCA) on the MI segment." "The patient presented with generalized tonic-clonic ...
Research on aneurysm discussed by N. Paraskevas and co-researchers.(Clinical report)
Sep 04, 2008 ... According to recent research from Paris, France, "This prospective, observational study evaluated the safety and efficacy of superficial femoral artery autograft reconstruction in the treatment of popliteal-artery aneurysms in the absence of a suitable saphenous vein. From March 1997 to ...
Scientists at University of Insubria target aneurysm.(Report)
Sep 04, 2008 ... According to recent research from Varese, Italy, "This study was undertaken to assess the indications and effectiveness of the Amplatzer vascular plug (AVP) system in interventional radiology. Over the past year, we selected 12 patients (seven men and five women; mean age 65.8 years, range ...
New angiology research reported from J.H. Rapp and co-authors.
Sep 04, 2008 ... "Microemboli occur frequently in patients with asymptomatic carotid atherosclerosis. In other vascular beds, microemboli are known to initiate an inflammatory response, causing organ dysfunction," researchers in the United States report (see also Angiology). "In the current ...
New angiology study findings have been published by scientists at University of North Carolina.(Report)
Sep 04, 2008 ... "Twenty to thirty percent of patients with symptomatic chronic venous insufficiency (CVI) are found to have combined superficial and deep venous reflux on duplex testing. It is currently unclear whether endovenous; ablation (EVA) of the saphenous vein will result in correction of CVI ...
Reports summarize angiology study results from Seoul National University.(Report)
Sep 04, 2008 ... "Cerebral microbleeds (MBs) are known to be indicative of bleeding-prone microangiopathy and may predict incident intracerebral haemorrhage. However, there is controversy concerning the causal relationship between the presence of MBs and haemorrhagic transformation (HTf) after ischaemic ...
Research conducted at Columbia University has provided new information about angiology.
Sep 04, 2008 ... According to a study from the United States, "Posttraumatic internal carotid pseudoaneurysm is an infrequent but potentially life-threatening condition that complicates approximately one-third of blunt carotid injuries." "Other types of injuries include dissection, thrombosis, ...
Study findings from Y.L. Chen et al broaden understanding of angiology.(Report)
Sep 04, 2008 ... " A fatal complication after liver transplantation is anastomotic embolization of the hepatic artery. In order to solve this problem, the portal venous arterialization (PVA) is used to reconstruct the hepatic arterial blood flow," scientists writing in the Chinese Medical Journal report ...
Investigators at University of Illinois, Medical Department target angiotensins.
Sep 04, 2008 ... "Increased growth and contraction of vascular smooth muscle cells (VSMCs) are major abnormalities in many vascular disorders. To investigate the signaling pathways that mediate these processes, we studied the expression of smooth muscle myosin light chain kinase (smMLCK) in VSMCs," ...
Reports from INSERM add new data to research in angiotensins.
Sep 04, 2008 ... According to recent research from Paris, France, "Aminopeptidase A (APA) generated brain angiotensin III, one of the main effector peptides of the brain renin angiotensin system, exerting a tonic stimulatory effect on the control of blood pressure in hypertensive rats. The distribution of ...
Research findings from University of California update understanding of angiotensins.
Sep 04, 2008 ... According to recent research published in the American Journal of Hypertension, "Because all clinically approved angiotensin-receptor blockers (ARBs) have good safety profiles and share the ability to block angiotensin II type 1 (AT,) receptors and reduce blood pressure, it is tempting to ...
Research from Georgetown University provides new data about angiotensins.
Sep 04, 2008 ... According to recent research from the United States, "The recycling of G-protein-coupled receptors (GPCR) to the cell surface after internalization plays an important role in the regulation of overall GPCR activity. The angiotensin II type I receptor (AT(1)R) belongs to class B GPCRs that ...
Studies from H.S. Bedair et al further understanding of angiotensins.
Sep 04, 2008 ... "Several therapeutic agents have been shown to inhibit fibrosis and improve regeneration after injury in skeletal muscle by antagonizing transforming growth factor-beta 1. Angiotensin receptor blockers have been shown to have a similar effect on transforming growth factor-beta 1 in a ...
Reports by L.D. Berrizbeitia and co-researchers describe recent advances in aortic dissection.
Sep 04, 2008 ... According to a study from the United States, "Ascending aorta replacement for acute aortic dissection repair was carried out in a 29-year-old man without the use of blood or blood products. Intraoperative blood loss was minimized with the use of biological glues and red cell salvage." ...
Scientists at Shandong University target apoptosis.(Report)
Sep 04, 2008 ... "Ouabain is Na+/K+ ATPase inhibitor and an endogenous regulator of blood pressure, it has dual effect on vascular endothelial cells(VEC) cell growth and VEC apoptosis is contributed to vascular dysfunction involved in vascular remolding. However, the precise mechanisms of apoptosis induced ...
Study findings on apoptosis are outlined in reports from University of Heidelberg.
Sep 04, 2008 ... According to a study from Mannheim, Germany, "Marked reduction in apoptosis is a hallmark of early colon tumour growth and the vast majority of these tumours exhibit a loss of expression of the glycoprotein carcinoembryonic-antigen-related cell adhesion molecule 1 (CEACAM1). We recently ...
New findings from Niigata University in the area of arteriovenous fistula described.(Report)
Sep 04, 2008 ... According to recent research from Niigata, Japan, "Transvenous embolization (TVE) for the treatment of a cavernous sinus (CS) dural arteriovenous fistula (DAVF) occasionally causes cranial nerve palsy (CNP). Overpacking of coils is considered to result in CNR The purpose of this study was ...
Study results from T. Ohta and colleagues broaden understanding of arteriovenous fistula.
Sep 04, 2008 ... According to recent research from Osaka, Japan, "The authors present a case of spinal dural arteriovenous fistula with fluctuations in symptoms following embolization. Superselective injection of 33% N-butyl cyanoacrylate, into the feeding vessel resulted in the complete occlusion of the ...
New arthroplasty research from University of Calgary discussed.
Sep 04, 2008 ... In this recent study, researchers in Calgary, Canada conducted a study "To improve access to care, many jurisdictions have proposed waiting-time benchmarks and guarantees. We assessed the willingness of patients to consider changing their surgeon to one with a shorter waiting time for ...
Research from RWTH Aachen University reveals new findings on arthroplasty.
Sep 04, 2008 ... According to a study from Aachen, Germany, " Hydrolytic debonding of the metal-cement interface is one of the main reasons for aseptic loosening in cemented hip arthroplasty. Materials and methods BiContact femur stems (CoCrMo-/TiAl6V4-alloy) were coated by a silica/silane interlayer ...
Reports from University of California add new data to research in artificial chromosomes.
Sep 04, 2008 ... According to recent research published in the Journal of Neuroscience, "To elucidate the pathogenic mechanisms in Huntington's disease (HD) elicited by expression of full-length human mutant huntingtin (fl-mhtt), a bacterial artificial chromosome (BAC)-mediated transgenic mouse model ...
New artificial neural networks study findings have been published by S. Dosen and colleagues.
Sep 04, 2008 ... "We developed a method for use of accelerometers and force sensing resistors (FSRs) within an optimal controller of walking for hemiplegic individuals. The data from four dual-axis accelerometers and four FSRs were inputs, while six muscle activation profiles were outputs," scientists in ...
Research from James Cook University, Medical Department has provided new information about atherosclerosis.
Sep 04, 2008 ... " Osteoprotegerin (OPG) and osteopontin (OPN) have been identified within unstable atherosclerosis and circulating concentrates have been linked to cardiovascular events. We studied the influence of OPG and OPN on endothelial adhesion molecule expression and monocyte binding," researchers ...
Study results from Afyon Kocatepe University, Medical Department provide new insights into atherosclerosis.
Sep 04, 2008 ... According to recent research from Afyon, Turkey, " Atherosclerotic vascular disease is a major cause of morbidity and mortality for patients with end-stage renal disease on maintenance hemodialysis. Early atherosclerotic changes of the arterial wall can be evaluated by intima-media ...
New atrial fibrillation study findings have been reported by researchers at Stanford University.
Sep 04, 2008 ... According to recent research published in the Journal of Cardiovascular Electrophysiology, "Efficacy, Safety, and Outcome of AF Ablation in Septuagenarians. Catheter ablation is an effective treatment for atrial fibrillation (AF)." "The outcome of AF ablation in septuagenarians ...
New research on atrial fibrillation from I. Vanwijk and co-authors summarized.
Sep 04, 2008 ... "Published data suggest that patients with cerebral ischaemia and atrial fibrillation (CIAF) have higher inhospital mortality than patients with cerebral ischaemia of arterial origin ( CIAO). Data on long term risks are scarce," scientists in Netherlands report (see also Atrial ...
Research from Kyungpook National University, Medical Department reveals new findings on atrial myxoma.
Sep 04, 2008 ... According to recent research from South Korea, "Carney complex is a rare autosomal-dominant familial tumor syndrome that involves the triad of myxoma, mucocutaneous pigmentation, and endocrine overactivity. To the best of the authors' knowledge, there are no reports of multiple fusiform ...
Data on B-cell lymphoma detailed by researchers at University of Debrecen.
Sep 04, 2008 ... "Recent results suggest that B cells may have multiple pathogenic roles in systemic sclerosis (SSc) and there may be increased incidence of B cell lymphomas in SSc. Here, we assessed the prevalence of lymphomas in a large SSc cohort," scientists writing in the journal Clinical Rheumatology ...
Data on B-cell lymphoma published by A. Martinez and colleagues.
Sep 04, 2008 ... According to a study from the United States, "To assess the role of interferon regulatory factor (IRF) 8 in B-cell development and lymphomagenesis, we studied its expression in reactive lymphoid tissues.. its relationship to other B-cell transcription factors, and its expression in a ...
New B-cell lymphoma data have been reported by L. Tracey and co-authors.
Sep 04, 2008 ... " Immunoglobulin gene somatic hypermutation is a biologically relevant and clinically useful prognostic factor in different types of low-grade B-cell lymphomas, including chronic lymphocytic leukemia, mantle cell lymphoma and splenic marginal zone lymphoma. Design and Methods With the aim ...
Research reports on B-cell lymphoma from Mie University, Medical Department provide new insights.
Sep 04, 2008 ... According to recent research from Tsu, Japan, " De novo CD5-positive diffuse large B-cell lymphoma (CD5(+) DLBCL) is clinicopathologically and genetically distinct from CD5-negative (CD5(-)) DLBCL and mantle cell lymphoma. The aim of this retrospective study was to clarify the ...