Recently added articles from British Journal of Biomedical Science:
Differences in lymphocyte profile between BAL fluid and human lung tissue from patients with interstitial lung disease
Apr 01, 2008; Fujimori, F; Shimizu, T; Takada, T; Narita, J; Suzuki, E; Gejyo, F ... ABSTRACT Bronchoalveolar lavage (BAL) is a technique that samples the inflammatory cells from distal airways and alveoli; however, it is unclear whether or not cellular profiles in the BAL fluid reflect the cellular components of the lung parenchyma in interstitial lung disease (ILD) ....
Use of softening agents to improve the production of formalin-fixed, paraffin-embedded sections of nail tissue: an assessment
Apr 01, 2008; Orchard, G E; Torres, J; Sounthararajah, P ... ABSTRACT The use of tissue softeners to enhance the quality of tissue sections of heavily keratotic tissue is not widely published. There are very few indicators in the scientific literature that attempt to compare and contrast the benefits and disadvantages of such techniques, as most ...
The relationship between chronic glycaemic control and oxidative stress in type 2 diabetes mellitus
Apr 01, 2008; Whiting, P H; Kalansooriya, A; Holbrook, I; Haddad, F; Jennings, P E ... ABSTRACT This study compares the lipid peroxidation marker urinary thiobarbituric acid reactive substances (TBARS) and antioxidants including plasma α-tocopherol (vitamin E), plasma (P-GSH-Px) and erythrocyte glutathione peroxidase (E-GSH-Px) activities, and plasma selenium levels ...
Effect of toluene exposure on the antioxidant status and apoptotic pathway in organs of the rat
Apr 01, 2008; Kamel, M A El-Nabi; Shehata, M ... ABSTRACT The chronic abuse of the solvent toluene results in structured and functional impairment of various organs. However, the pathophysiological mechanisms that cause these impairments of function are not clearly understood. This study aims to assess the effect of chronic toluene ...
Protective role of Ocimum canum plant extract in alcohol-induced oxidative stress in albino rats
Apr 01, 2008; George, S; Chaturvedi, P ... ABSTRACT Ethanol is the most frequently abused drug and causes a variety of pathological disturbances. It causes toxicity to tissues by generating free radicals during the course of its metabolism that can damage cellular structure and function, especially in hepatocytes. This study ...
First detection of a class 2 integron among clinical isolates of Serratia marcescens
Apr 01, 2008; Crowley, D; Cryan, B; Lucey, B ... ABSTRACT Serratia marcescens is a frequent nosocomial isolate and is associated with a variety of clinical sources, including blood, urine and sputum, and can cause significant infection. Infections can be difficult to treat due to its resistance to a variety of antimicrobial agents. An ...
Serum metastasin mRNA is an important survival predictor in breast cancer
Apr 01, 2008; El-Abd, E; El-Tahan, R; Fahmy, L; Zaki, S; Faid, W; Sobhi, A; Kandil, K; El-Kwisky, F ... ABSTRACT This study investigates the possible prognostic role of serum metastasin messenger RNA (mRNA) in breast carcinoma as a non-invasive screening tool, and determines metastasin mRNA in the serum of breast cancer patients with high sensitivity (85%) and specificity (100%). A ...
Genetic heterogeneity of the dnaK gene locus including transcription terminator region (TTR) in Campylobacter lari
Apr 01, 2008; Shitara, M; Tsuboi, Y; Sekizuka, T; Tazumi, A; Moore, J E; Millar, B C; Taneike, I; Matsuda, M ... ABSTRACT Nucleotide sequences of approximately 3.1 kbp consisting of the full-length open reading frame (ORF) for grpE, a non-coding (NC) region and a putative ORF for the full-length dnaK gene (1860 bp) were identified from a urease-positive thermophilic Campylobacter (UFTC) CF89-12 ...
Introduction of automatically generated comment in clinical biochemistry: an audit of technical effectiveness
Apr 01, 2008; Twomey, P J; Jones, B J; Pledger, D R ... Laboratories in the UK have seen a large increase in the number of tests requested since the introduction of the new General Medical Services contract in 2004. This increase is in addition to the underlying steady increase observed over the past few decades. However, a steep increase was not ...
Detection of HCV antibody-negative donations: Saudi experience with nucleic acid testing
Apr 01, 2008; Hajeer, A H; Gharawi, K Al; Rayes, W Al; Qasem, L; Merenkov, Z; Balwi, M Al ... Currently, the risk of contracting hepatitis C virus (HCV) or human immunodeficiency virus (HIV) in the blood transfusion setting is very low. The sensitivity of donor screening using serological tests and donor selection practices ensures that transfused blood is an extremely safe product ....
Comparison of clustered, regularly interspaced short palindrome repeats (CRISPRs) in viridans streptococci (Streptococcus gordonii, S. mutans, S. sanguinis, S. thermophilus) and in S. pneumoniae
Apr 01, 2008; Moore, J E; Mason, C K; Coulter, W A; McCarron, P; Leggett, P; Montgomery, J; Goldsmith, C E ... Clustered, regularly interspaced short palindrome repeats (CRISPRs) have been described in several archaea and bacteria. An in silica analysis of pneumococcal and viridans group streptococci (VGS) demonstrated the presence of several confirmed and putative new CRISPR regions. The sharing of ...
Immunological Tolerance: Methods and Protocols. Methods in Molecular Biology, Vol. 380
Apr 01, 2008; Dawson, M ... Immunological Tolerance: Methods and Protocols. Methods in Molecular Biology, Vol. 380 P. J. Fairchild ed. Tolawa, NJ: Humana Press, 2007. ISBN 978-1-58829-652-8. $159. 477 pp. As the title of the book implies, this volume brings together a number of chapters that outline methodology in ...
Early municipal bacteriology in Brighton, Aberdeen and Bristol: blessing or burden?
Apr 01, 2008; Hardy, S P; Watson, F R ... ABSTRACT In contrast to the idea that bacteriology was introduced as a tool for the diagnosis and management of the individual patient, this review highlights the work of the municipal bacteriological laboratory in the United Kingdom to illustrate how bacteriological laboratories were ...