Recently added articles from British Journal of Biomedical Science:
Fluorescence (FISH) and chromogenic (CISH) in situ hybridisation in prostate carcinoma cell lines: comparison and use of virtual microscopy
Oct 01, 2008; ... ABSTRACT Chromogenic in situ hybridisation (CISH) has become an attractive alternative to fluorescence in situ hybridisation (FISH) due to its permanent stain which is more familiar to pathologists and because it can be viewed using light microscopy. The aim of the present study is to ...
Correlation of Bmi-1 expression and telomerase activity in human ovarian cancer
Oct 01, 2008; ... ABSTRACT This study investigates the correlation between the oncoprotein Bmi-1 and telomerase activity in ovarian cancer. A real-time polymerase chain reaction (PCR) method is used to detect the messenger RNA (mRNA) expression of Bmi-1 protein in 47 ovarian epithelial cancer cases, and ...
Comparative in vitro antimicrobial procedural efficacy for susceptibility of Staphylococcus aureus, Escherichia coli and Pseudomonas species to chloramphenicol, ciprofloxacin and cefaclor
Oct 01, 2008; ... ABSTRACT The present study assesses the reliability of the in vitro susceptibility tests E-test, disc diffusion and Alamar blue-based microbroth dilution assays for evaluating the efficacy of chloramphenicol, ciprofloxacin and cefaclor against clinical and reference isolates of ...
Reduction of Staphylococcus epidermidis adhesion to indwelling medical devices: a simple procedure
Oct 01, 2008; ... ABSTRACT The present study aims to find a method to reduce Staphylococcus epidermidis adhesion to acrylic and silicone -two materials used commonly in medical devices - by heparin and gentian violet surface preconditioning. Different periods of heparin preconditioning are studied to ...
Detection of ESBL bacteria from clinical specimens: evaluation of a new selective medium
Oct 01, 2008; ... ABSTRACT Selective screening media for extended-spectrum β-lactamase (ESBL)-producing bacteria are needed to guide antibiotic therapy and institute appropriate infection control measures. This study evaluates a selective cefpodoxime-incorporated chromogenic agar (CCA) medium for ...
Cloning and structural analysis of the full-length cytolethal distending toxin (cdt) gene operon from Campylobacter lari
Oct 01, 2008; ... ABSTRACT Polymerase chain reaction (PCR) amplicons (approximately 2.5 kbp) encoding a cdt gene operon and two partial and putative open reading frames (ORFs) were identified in six urease-negative (UN) Campylobacter lari isolates using a new PCR primer pair constructed in silico. Three ...
Application of microwave heat to paraffin sections: rapid adhesion of sections to slides
Oct 01, 2008; ... Tissue sections of paraffin-embedded tissue cut and mounted on glass slides for subsequent staining must be heated to melt the paraffin wax in order to adhere the tissue section to the slide. The protocol employed in most cellular pathology departments is heating for 10-30 min in a 70°C oven ....
Should long-haul flights carry antibiotics on board to treat acute bacterial meningitis and meningococcal septicaemia?
Oct 01, 2008; ... Acute bacterial meningitis and meningococcal septicaemia represent an import medical emergency in medical microbiology. Several studies suggest that early intervention with intravenous (iv) antibiotics, particularly the β-lactam agents (e.g., benzylpenicillin) in patients with signs and ...
Mixed HSV-1 and HSV-2 infection in a patient attending a GUM clinic
Oct 01, 2008; ... Infection with herpes simplex virus (HSV) is usually benign (e.g., oral cold sores); however, beyond its well-known embarrassing and painful symptoms, it can occur in critical anatomical sites (e.g., eye or central nervous system). Furthermore, infection acquired during pregnancy can have ...
Cell signalling is the music of life
Oct 01, 2008; ... ABSTRACT Cell signalling is an immensely important topic in biological and biomedical sciences, and one which has an ever-increasing literature. As more and more is known about it, and more components are discovered, it is getting harder and harder to visualise how it all might work to ...
Good analytical practice: statistics and handling data in biomedical science. A primer and directions for authors. Part 1: Introduction. Data within and between one or two sets of individuals
Oct 01, 2008; ... ABSTRACT The biomedical scientist is bombarded on a daily basis by information, almost all of which refers to the health status of an individual or groups of individuals. This review is the first of a two-part article written to explain some of the issues related to the presentation and ...
Biomedical Calculations: Principles and Practice
Oct 01, 2008; ... Biomedical Calculations: Principles and Practice R. F. Burton. Chichester: John Wiley, 2008. ISBN 978-0-470-51910-3 (hardback) £70. ISBN: 978-0-470-51911-0 (paperback) £22.50. 310 pp The ability to 'do' calculations is an essential skill of the biomedical scientist. It is not a skill ...
Enterprise for Life Scientists: Developing Innovation and Entrepreneurship in the Biosciences
Oct 01, 2008; ... Enterprise for Life Scientists: Developing Innovation and Entrepreneurship in the Biosciences D. Adams, i. Sparrow eds. Bloxham: Scion, 2007. ISBN 978 1 904842 36 1. £24.99. 250 pp. This easily portable volume is an excellent primer for undergraduates learning about enterprise or for ...
Microscope Image Processing
Oct 01, 2008; ... Microscope Image Processing Q. Wu, F. A. Merchant, K. R. Castleman. Oxford : Academic Press, 2008. ISBN 978-0-12-372578-3. £49.99. 548 pp. This book is a specialised publication, especially useful as an excellent reference tome for those working in image analysis and measurement fields ...
Diabetes and Cancer: Epidemiological Evidence and Molecular Links
Oct 01, 2008; ... Diabetes and Cancer: Epidemiological Evidence and Molecular Links K. Masur, F. Thevenod, K. S. Zanker eds. Basel: Karger, 2008. ISBN 978-3-8055-8640-5. $148. 148 pp. The text focuses on common molecular and clinical features of cancer and diabetes supported by epidemiological evidence ....
Effect of low serum total protein on sodium and potassium measurement by ion-selective electrodes in critically ill patients
Jul 01, 2008; ... ABSTRACT Hypoproteinaemia may lead to spuriously high electrolyte values using indirect ion-selective electrodes (ISE) compared to direct ISEs. This study evaluates the impact on electrolyte status assessment of direct compared to indirect ISE sodium and potassium measurements in samples ...
Oxidative damage indices for the assessment of subclinical diabetic macrovascular complications
Jul 01, 2008; ... ABSTRACT Subclinical cardiovascular disease (SCVD), including complications in diabetes, is associated with oxidative damage and precedes future cardiovascular disease (CVD). Hence, assessment and management of oxidative damage is imperative. This study investigates biomarkers associated ...
Evaluation of a new Staphylococcus aureus latex agglutination kit, Prolex Staph Xtra, against other third-generation kits
Jul 01, 2008; ... ABSTRACT Staphylococcus aureus, including methicillin-resistant strains, continues to be a common cause of infection/colonisation, which necessitates accurate and prompt diagnosis in the laboratory. Several rapid agglutination tests that aid this function are available, and some have ...
Molecular characterisation of urease genes from urease-positive thermophilic campylobacters (UPTC)
Jul 01, 2008; ... ABSTRACT This study aims to clarify the molecular characteristics of the urease gene operon from urease-positive thermophilic Campylobacters (UPTC) obtained from different sources and in various countries. Sequence heterogeneity was observed for the promoter structures at the -35-like ...
Phaeochromocytoma presenting with coexisting acute renal failure, acidosis and in hyperglycaemic emergency
Jul 01, 2008; ... Phaeochromocytoma is a relatively uncommon tumour of the adrenal medulla, and its association with sustained or paroxysmal hypertension has also been labelled 'the great mimic', with a variety of typical or non-typical clinical manifestations.1 Reversible acute renal failure, although rare, can ...