Canadian Journal of Psychiatry back issues from July 2008:
Rebuttal to Dr Streiner: Can the "Evil" in the "Lesser of 2 Evils" Be Justified in Placebo-Controlled Trials?
Jul 01, 2008; ... Can J Psychiatry 2008;53(7):433 Dr Streiner admits to possible harm to participants in placebo-controlled trials with his statement that they are a "necessary evil," even when effective drugs exist. His justification rests on his supposition that they produce "unambiguous" results, ...
When What Is Ethical May Not Be Right: A Reply to Dr Glass
Jul 01, 2008; ... Can J Psychiatry 2008;53(7):434 Dr Glass raises numerous excellent arguments against the use of placebo controls in trials when existing therapies exist. These include: wasting resources or putting participants at risk for no possible gain; the well-being of the patient; and the ...
Reducing the Burden of Depression
Jul 01, 2008; ... Objective: To consider why the burden of depression persists. Method: The epidemiology and disability associated with depression were reviewed to consider whether depression persists because: the causes are overwhelming, prevention is ineffective, the disease is difficult to detect or ...
Anxiety in a Socially High-Risk Sample of Pregnant Women in Canada
Jul 01, 2008; ... Objective: To determine if an anxiety dimension in the Edinburgh Postnatal Depression Scale (EPDS) could be identified in a sample of pregnant women with high social risk factors. Method: Four hundred women attending prenatal outreach programs, most of whom were single, low-income, and ...
Is Cognitive-Behavioural Therapy More Effective Than Psychoeducation in Bipolar Disorder?
Jul 01, 2008; ... Objective: Psychosocial research in bipolar disorder (BD) has not yet assessed the relative benefits of a short course of psychoeducation (PE), compared with a longer course of cognitive-behavioural therapy (CBT) containing psychoeducational principles. This pilot study evaluated the efficacy ...
The Lesser of 2 Evils: The Ethics of Placebo-Controlled Trials
Jul 01, 2008; ... Abbreviations used in this article ADR adverse drug reaction ES effect size RCT randomized controlled trial TAU treatment as usual Can J Psychiatry 2008;53(7):430-432 It is widely accepted that the most powerful research design to assess the ...
Ethical Obligations and the Use of Placebo Controls
Jul 01, 2008; ... Can J Psychiatry 2008;53(7):428-429 The double-blind, randomized, placebo-controlled clinical trial is considered the best method for collecting evidence about diagnostic, therapeutic, or preventive interventions. Well-conducted placebo-controlled trials have high internal validity ....
Caregiving and Illness Beliefs in the Course of Psychotic Illness
Jul 01, 2008; ... Objective: Informal caregivers play a central role in patient care, and caregiving can provide positive and negative experiences. Negative caregiving experiences are associated with distress. This study investigates associations between caregiving appraisals in psychosis, distress, and 3 key ...
Psychosomatics-The Uses of Psychotherapy
Jul 01, 2008; ... Psychotherapy Psychosomatics-The Uses of Psychotherapy Peter Shoenberg. New York (NY): Palgrave Macmillan; 2007. 272 p. US$33.95 Reviewer rating: Fair Review by C Alex Adsert, MD, FRCPC Hamilton, Ontario The Forward of this book presents the purpose "to integrate ...
Major Depression Prevalence Is Very High, But the Syndrome Is a Poor Proxy for Community Populations' Clinical Treatment Needs
Jul 01, 2008; ... Objectives: Some basic questions about the epidemiology of major depression (MD) remain open to debate and interpretation. Prevalence is a case in point. There have been claims that prevalence has been both over and underestimated. This review is an attempt to reconcile this apparent ...
Bipolar Disorder in Later Life
Jul 01, 2008; ... Bipolar Disorder Bipolar Disorder in Later Life Martha Sajatovic and Frederic C Blow, editors. Baltimore (MD): The Johns Hopkins University Press; 2007. 257 p. US$50.00 Reviewer rating: Excellent Review by Kenneth Shulman, MD Toronto, Ontario One of the chapters ...
Is It Time to Revise Our Understanding and Management of Depression?
Jul 01, 2008; ... Can J Psychiatry 2008;53(7):409-410 Each of the 2 provocative papers in this In Review challenges us to rethink our understanding of and approach toward depression. Dr Scott Patten,1 one of Canada's preeminent psychiatric epidemiologists, presents powerful new evidence that refutes ...
Nature and Frequency of Aggressive Behaviours Among Long-Term Inpatients With Schizophrenia: A 6-Month Report Using the Modified Overt Aggression Scale
Jul 01, 2008; ... Objective: Previous reports of violence rates in psychiatry settings varied substantially. The main goal of this preliminary study was to prospectively record all violent incidents committed by chronic inpatients with schizophrenia (Sz) using a validated instrument. A secondary objective was to ...
Prevalence of Autism Among Adolescents With Intellectual Disabilities
Jul 01, 2008; ... Objective: To estimate the prevalence of autism in an epidemiologically-derived population of adolescents with intellectual disabilities (ID). Method: The prevalence of autism was examined using the Autism Diagnostic Interview-Revised, with appropriate care taken in assessing lower ...
Cross-Cultural Validation of the Empathy Quotient in a French-Speaking Sample
Jul 01, 2008; ... Objective: The Empathy Quotient (EQ) is a self-report that was developed to measure the cognitive and affective aspects of empathy. We further evaluated its validity in 2 studies. Method: The psychometric qualities of the French version of the EQ, and its correspondence with 2 other ...