Cancer Weekly back issues from January 2009:
New life sciences data have been reported by scientists at University College.
Jan 06, 2009 ... "The genus Alphavirus includes several potentially lethal human viruses. Additionally, species such as Sindbis virus and Semliki Forest virus are important vectors for gene therapy, vaccination and cancer research, and important models for virion assembly and structural analyses," ...
Scientists at Stanford University, Medical Department describe research in life sciences.
Jan 06, 2009 ... According to recent research published in the journal Molecular Therapy, "Promoters that limit transgene expression to tumors play a vital role in cancer gene therapy. Although tumor specific, the human Survivin promoter (pSurv) elicits low levels of transcription." "A ...
GIS AIDS Alaska Native Health Study.
Jan 06, 2009 ... The Alaska Native Tribal Health Consortium will publish a study in January 2009 which utilizes Geographic Information Systems (GIS) to analyze incidents of disease and injury across Alaska tribal health regions (see also New Urban Research, Inc.). GIS technology allows the ...
New stem cell research study findings have been reported from University of Munich.
Jan 06, 2009 ... According to recent research from Munich, Germany, "Genomic integration by the Streptomyces bacteriophage phi C31 integrase is a promising tool for non-viral gene therapy of various genetic disorders. We investigated the phi C31 integrase recombination activity in T cell derived cell ...
New research on cancer gene therapy from Second Military Medical University, Department of Gastroenterology summarized.(Report)
Jan 06, 2009 ... New investigation results, 'Nuclear factor-kappaB p65/relA silencing induces apoptosis and increases gemcitabine effectiveness in a subset of pancreatic cancer cells,' are detailed in a study published in Clinical Cancer Research. According to recent research from Shanghai, People's ...
Data from A. Kiral and colleagues advance knowledge in adamantinoma.(Clinical report)
Jan 06, 2009 ... "This article presents 3 cases of tibial diaphyseal adamantinoma. All 3 cases were men who reported pain and swelling but no history of trauma," researchers in Istanbul, Turkey report (see also Adamantinoma). "The diagnosis of adamantinoma was suspected with radiographic and ...
Researchers at University of Kansas target adenomatous polyposis coli.
Jan 06, 2009 ... According to recent research from the United States, "The tumor suppressor adenomatous polyposis coli (APC) is implicated in regulating multiple stages of the cell cycle. APC participation in G1/S is attributed to its recognized role in Wnt signaling." "APC function in the G2/M ...
Studies from G.R. Pinto et al further understanding of aging.
Jan 06, 2009 ... According to recent research from Brazil, "Werner syndrome (WS) is a premature aging disorder characterized by early onset of symptoms related to normal aging and by a high predisposition to various types of cancer, including gliomas. WS is caused by inherited recessive mutations in the ...
Research on angiosarcoma discussed by scientists at University of Strasbourg.
Jan 06, 2009 ... According to a study from Strasbourg, France, "Angiosarcoma represents 1 to 2% of soft tissue tumors. It originates from endothelial cells of small blood vessels and may affect a variety of organs, including the retroperitoneum, skeletal muscle, subcutis, liver, heart and breast." ...
Study results from University of Calgary, Medical Department provide new insights into apoptosis.
Jan 06, 2009 ... According to a study from Calgary, Canada, "ING proteins interact with core histones through their plant homeodomains (PHDs)(1-4) and with histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes to alter chromatin structure(5-7). Here we identify a lamin interaction domain ...
Studies from Tufts University, Medical Department update current data on astrocytoma.
Jan 06, 2009 ... "A 2-year-old, female hedgehog presented with an 8-month history of progressive, ascending paresis/paralysis and was tentatively diagnosed with wobbly hedgehog syndrome. She died awaiting further diagnostic tests, and the owners consented to postmortem examination," researchers in the ...
Research from S.N. Stacey and colleagues provide new insights into basal cell cancer.
Jan 06, 2009 ... "To search for new sequence variants that confer risk of cutaneous basal cell carcinoma (BCC), we conducted a genome-wide SNP association study of 930 Icelanders with BCC and 33,117 controls. After analyzing 304,083 SNPs, we observed signals from loci at 1p36 and 1q42, and replicated these ...
Data on biopsy discussed by L. Voltolini and colleagues.(Report)
Jan 06, 2009 ... According to recent research from Siena, Italy, "The aim of this study was to evaluate if transpleural diagnostic methods as percutaneous fine-needle aspiration biopsy (FNAB) or tumour wedge resection by video-assisted thoracoscopic surgery (VATS) impact on local recurrence and long term ...
New data from National Institutes of Health illuminate research in biopsy.
Jan 06, 2009 ... According to recent research from the United States, "Targeted prostate biopsy is challenging because no currently established imaging modality is both accurate for prostate cancer diagnosis and cost-effective for real-time procedure guidance. A system that fuses real-time transrectal ...
Research data from K. Dorota and colleagues update understanding of biopsy.
Jan 06, 2009 ... "Core biopsy of liver mass comprises at) alternative to fine needle aspiration biopsy. We decided to compare diagnoses established with the use of both methods and assess whether the use of both methods together is warranted," scientists writing in the journal Hepato - Gastroenterology ...
Investigators at Fudan University target bladder cancer.
Jan 06, 2009 ... According to a study from Shanghai, People's Republic of China, "To elucidate the role of X-ray repair cross-complementing group 1 (XRCC1) R399Q and R194W genotypes in bladder cancer risk, all available studies were considered in the present meta-analysis, with 4152 patients and 5372 ...
New bladder cancer data have been reported by scientists at National Cancer Institute.
Jan 06, 2009 ... According to recent research from the United States, "In an initial study, to determine if rosiglitazone had chemopreventive activity, Fischer-344 female rats were administered twice weekly doses of hydroxybutyl(butyl)nitrosamine (OH-BBN), a urinary bladder specific carcinogen, for 8 ...
New bladder cancer study findings have been reported by scientists at Radboud University.
Jan 06, 2009 ... According to recent research from Netherlands, "We conducted a genome-wide SNP association study on 1,803 urinary bladder cancer (UBC) cases and 34,336 controls from Iceland and The Netherlands and follow up studies in seven additional case-control groups (2,165 cases and 3,800 controls) ....
Studies from E. Stefani and colleagues reveal new findings on bladder cancer.
Jan 06, 2009 ... "To determine the major dietary patterns associated with bladder cancer risk, we conducted a principal components analysis (PCA) in a case-control study from Uruguay. A total of 255 newly diagnosed and microscopically confirmed cases of transitional cell carcinoma of the bladder and 501 ...
Study data from University of Virginia update understanding of bladder cancer.
Jan 06, 2009 ... "Cell migration is essential to cancer invasion and metastasis and is spatially and temporally integrated through transcriptionally dependent and independent mechanisms. As cell migration is studied in vitro, it is important to identify genes that both drive cell migration and are ...
New bone research study findings reported from Yokohama City University, Medical Department.
Jan 06, 2009 ... In this recent study, researchers in Kanagawa, Japan conducted a study "To describe vertical distraction osteogenesis of a scapular flap and removable lip support for oral rehabilitation after surgical creation of an ablative defect of the mandible. Case report. A 70-year-old man who was ...
Researchers from University of Florida publish findings in brain cancer.(Report)
Jan 06, 2009 ... According to recent research from the United States, "Stereotactic radiosurgery is a commonly used treatment method in the management of metastatic brain tumors. When lesions enlarge after radiosurgery, it may represent tumor regrowth, radiation necrosis, or both." "The purpose ...
New brain metastasis data have been reported by C. Nieder and co-authors.(Report)
Jan 06, 2009 ... "The purpose of this study was to evaluate the performance of the new Graded Prognostic Assessment (GPA) index, which was recently developed from data in the Radiation Therapy Oncology Group (RTOG) database, in patients treated with surgical resection of brain metastases and postoperative ...
Findings from C. Mathelin and co-authors provide new insights into breast cancer.(Report)
Jan 06, 2009 ... According to recent research from Strasbourg, France, "This study aimed at evaluating the performance of an intraoperative gamma camera, named CarolIReS, to detect axillary drainage and to assess the removal of sentinel lymph nodes (SLN) in breast surgery. SLN biopsy was performed on 25 ...
Findings from J. Stagg et al in breast cancer reported.
Jan 06, 2009 ... "Despite the development of human epidermal growth factor receptor-2 (ErbB-2/HER2)-targeted therapies, there remains an unmet medical need for breast cancer patients with ErbB-2 overexpression. We investigated the therapeutic activity of an agonist mAb to mouse tumor necrosis ...
Findings from Menoufiya University, Medical Department broaden understanding of breast cancer.(Clinical report)
Jan 06, 2009 ... According to a study from Egypt, "This prospective study was designed to assess the utility of the dual time point imaging technique using 2-[F-18]-fluoro-2-deoxy-D- glucose (FDG) positron-emission tomography/computed tomography (PET/CT) to detect primary breast cancer and to determine ...
Findings from S.W.W. Chan and co-authors broaden understanding of breast cancer.(Report)
Jan 06, 2009 ... According to recent research published in the World Journal of Surgery, "The purpose of this study was to evaluate the performance of high-resolution ultrasonography in the detection of clinically and mammographically occult breast cancer. From September 2003 to November 2006, a total of ...
Findings from University of North Dakota broaden understanding of breast cancer.
Jan 06, 2009 ... According to recent research from the United States, "While increased urokinase-type plasminogen activator (uPA) expression in breast cancer tissue is directly associated with poor prognosis, recent evidence suggests that uPA overexpression may suppress tumor growth and prolong survival ....
Findings from Yale University advance knowledge in breast cancer.
Jan 06, 2009 ... "A population-based cohort study was conducted in Shanghai, China, to investigate the relationship between family cancer history in first-degree relatives and risk of breast cancer. A total of 570 newly diagnosed breast cancer patients were identified from the cohort of 73,222 women during ...
New breast cancer findings from C.Z. Wang and co-researchers published.(Report)
Jan 06, 2009 ... "Former studies have shown that extract from American ginseng (Panax quinquefolius) may possess certain antiproliferative effects on cancer cells. In this study, the chemical constituents of both untreated and heat-processed American ginseng and their antiproliferative activities on human ...
New breast cancer research from Kaiser Permanente discussed.(Clinical report)
Jan 06, 2009 ... According to a study from the United States, "With 2.3 million breast cancer survivors in the US today, identification of modifiable factors associated with breast cancer recurrence and survival is increasingly important. Only recently new studies have been designed to examine the impact ...
New breast cancer research has been reported by scientists at Indiana University.(Report)
Jan 06, 2009 ... "Although American women are living longer after a breast cancer diagnosis, they may experience significant alterations in sexual function. However, little is known about the types of strategies that women are interested in using to address these sexual issues," investigators in the United ...
New breast cancer research has been reported by scientists at Virginia Commonwealth University.
Jan 06, 2009 ... According to a study from the United States, "This exploratory study assessed relationships among education, tolerance for ambiguity, and genetic testing awareness in light of implications for cancer genetics education. Cross-sectional analyses were conducted from self-administered written ...
New breast cancer study findings recently were reported by researchers at University Hospital.(Clinical report)
Jan 06, 2009 ... "The objective of this study was to identify barriers and facilitators that professionals see when implementing a program incorporating ultra-short hospital admission in the treatment of breast cancer. Such an intervention is an essential step when designing a strategy for implementation ...
New breast cancer study results from L.X. Yan et al described.
Jan 06, 2009 ... "To investigate the global expression profile of miRNAs in primary breast cancer (BC) and normal adjacent tumor tissues (NATs) and its potential relevance to clinicopathological characteristics and patient survival, the genome-wide expression profiling of miRNAs in BC was investigated ...
New breast cancer study results reported from G.V. Ripoll et al.
Jan 06, 2009 ... "The vasopressin peptide analog desmopressin has been used during surgery to prevent bleeding in patients with coagulation defects. Recent experimental and clinical data revealed that perioperative desmopressin therapy can minimize the spread and survival of residual cancer cells," ...
New data from A. Howell et al illuminate research in breast cancer.
Jan 06, 2009 ... "Breast cancer incidence is increasing in all parts of the world. Although in Western countries death rates are declining, there is a need to make attempts to prevent the disease in order to reduce the trauma of diagnosis and treatment," scientists writing in the journal Best Practice & ...
New data from Seoul National University illuminate research in breast cancer.
Jan 06, 2009 ... "Triple-negative (TN) breast cancer, which is defined as being negative for the estrogen receptor (ER), the progesterone receptor (PR), and the human epidermal growth factor receptor 2 (HER-2), represents a subset of breast cancer with different biologic behaviour. We investigated the ...
New findings from Southern Illinois University describe advances in breast cancer.(Report)
Jan 06, 2009 ... According to recent research published in the journal Environmental Health, "High levels of dioxins in soil and higher-than-average body burdens of dioxins in local residents have been found in the city of Midland and the Tittabawassee River floodplain in Michigan. The objective of this ...
New findings reported from L.C.S. Thuler and co-authors describe advances in breast cancer.(Report)
Jan 06, 2009 ... "The primary aim of this study was to evaluate a programme called 'Touch of Life' (Toque de Vida in Portuguese) proposed to increase breast cancer screening awareness and provide free clinical breast examination (CBE) for asymptomatic women 40-69 years of age. Evaluation of the ...
Reports from P.H. Zahl et al highlight recent research in breast cancer.
Jan 06, 2009 ... "The introduction of screening mammography has been associated with sustained increases in breast cancer incidence. The natural history of these screen-detected cancers is not well understood," scientists in the United States report (see also Breast Cancer). "We compared ...
Research by M.Z. Papa and colleagues in breast cancer provides new insights.
Jan 06, 2009 ... In this recent report published in the Journal of Surgical Oncology, researchers in Tel Hashomer, Israel conducted a study "To address optimal timing of sentinel lymph node biopsy (SLNB) in breast cancer patients undergoing neoadjuvant treatment. The study population included 117 patients ...
Research from A.A. Elmabhouh and co-authors in the area of breast cancer published.
Jan 06, 2009 ... "Animal models are useful tools to study etiology, progress, and new treatments of disease and are an approximation of human disease for experimental study. Intracardiac injection of the human estrogen-independent breast cancer cell line MDA-MB-231 in nude mice is a well-characterized ...
Research from Comenius University has provided new data on breast cancer.(Report)
Jan 06, 2009 ... According to recent research from Martin, Slovakia, "Monotherapy with aromatase inhibitors has no established role in premenopausal breast cancer in women and is an area of future exploration. In this study, chemopreventive effects of anastrozole in the model of ...
Research from Malmo University yields new findings on breast cancer.
Jan 06, 2009 ... According to a study from Malmo, Sweden, "The main purpose was to compare breast cancer visibility in one-view breast tomosynthesis (BT) to cancer visibility in one- or two-view digital mammography (DM). Thirty-six patients were selected on the basis of subtle signs of breast cancer on ...
Research results from Georgetown University update knowledge of breast cancer.(Report)
Jan 06, 2009 ... According to recent research from the United States, "This study developed and evaluated a culturally tailored video guided by the health belief model to improve Chinese women's low rate of mammography use. Focus-group discussions and an advisory board meeting guided the video ...
Researchers from INSERM provide details of new studies and findings in the area of breast cancer.
Jan 06, 2009 ... "Our aim was to conduct an analytical validation in a routine laboratory setting of the cerb-B2/c-neu ELISA assay kit from Calbiochem (R) used to measure the extracellular domain (ECD) of HER2/neu in the serum of breast cancer patients. The evaluation was based on three different ...
Researchers from Mansoura University publish findings in breast cancer.
Jan 06, 2009 ... According to a study from Mansoura, Egypt, "The introduction of skin-sparing mastectomy has revolutionized both breast cancer surgery and breast reconstruction. Latissimus dorsi myocutaneous flap is a versatile flap that is gaining renewed popularity with the development of flap ...
Scientists at St. George's University detail research in breast cancer.
Jan 06, 2009 ... "In addition to its important role in the maintenance of the skeleton, there is mounting evidence that vitamin D has effects on other body systems, and that adequate supplies of vitamin D are likely to be required for optimal health. Vitamin D is obtained both from dietary sources and from ...
Scientists at University Hospital discuss research in breast cancer.(Report)
Jan 06, 2009 ... "A number of studies have shown that absence of myelotoxicity during chemotherapy is associated with worse outcome for various types of cancer, including carcinoma of the breast. The aim of this study was to determine whether myelosuppression in patients being treated with chemotherapy for ...
Scientists at University of Oklahoma publish new data on breast cancer.(Report)
Jan 06, 2009 ... According to a study from the United States, "Keratinocyte growth factor (KGF) produces a rapid increase in the proliferation and motility of estrogen receptor (ER)-positive breast cancer cells which is abolished by estrogen deprivation and/or anti-estrogen treatment. The present study ...
Studies conducted at L. Cyr et al on breast cancer recently published.
Jan 06, 2009 ... "There are several studies documenting that organosulfur compounds show promise as anticancer agents. Although some mechanisms of the antiproliferative activity of naturally occurring organosulfur compounds have been elucidated, few studies have reported the differential response of human ...
Studies from City Hospital update current data on breast cancer.(Report)
Jan 06, 2009 ... According to recent research published in the journal Clinical Radiology, "Recent protein expression profiling of breast cancer has identified specific subtypes with clinical, biological, and therapeutic implications. The aim of this study was to identify the mammographic correlates of ...
Studies from Fudan University have provided new data on breast cancer.(Report)
Jan 06, 2009 ... According to recent research published in the journal Anticancer Research, "The purpose of this study was to evaluate retrospectively the efficacy and safety of neoadjuvant chemotherapy with vinorelbine-containing regimens in elderly patient with locally advanced breast cancer (LABC). From ...
Studies from Georgetown University provide new data on breast cancer.
Jan 06, 2009 ... "To describe breast cancer risk perceptions, determine risk comprehension, and evaluate mammography adherence among Latinas. Latina women age >= 35, primarily from Central and South America, were recruited from community-based clinics to complete in-person interviews (n = 450)," scientists ...
Studies from Harvard University yield new data on breast cancer.
Jan 06, 2009 ... According to recent research from the United States, "Exposure to higher levels of both exogenous and endogenous hormone is associated with breast cancer risk." "Because of the association between breast cancer and HRT, only the minimal duration of HRT use is recommended for ...
Studies from University of Washington reveal new findings on breast cancer.
Jan 06, 2009 ... "Of the 411,000 breast cancer deaths around the world in 2002, 221,000 (54%) occurred in low- and middle-income countries (LMCs). Guidelines for breast health care (early detection, diagnosis, and treatment) that were developed in high-resource countries cannot be directly applied in LMCs, ...
Studies from Virginia Commonwealth University further understanding of breast cancer.(Clinical report)
Jan 06, 2009 ... According to recent research published in the journal Health Education & Behavior, "This study explored risk perceptions after breast cancer risk appraisal. The study involved a randomized trial of Women's Health clinic patients (>= 40 years old)." "Primary outcome was perceived ...
Studies in the area of breast cancer reported from Indiana University.
Jan 06, 2009 ... In this recent study, researchers in the United States conducted a study "To examine the experiences of being parented when mothers are diagnosed and treated for breast cancer from the perspectives of adolescent daughters. Research Approach: Empirical phenomenologic." ...
Study data from E. Tracey and co-authors update knowledge of breast cancer.(Report)
Jan 06, 2009 ... According to a study from Australia, "This study investigated associations of degree of spread at diagnosis of breast cancer and socio-demographic factors with the risk of death among NSW females diagnosed in 1980-2003. Trends by diagnostic period, socio-demographic differences, and the ...
Study data from J.D. Allen et al provide new insights into breast cancer.
Jan 06, 2009 ... According to a study from the United States, "Many breast cancer outreach programs assume that dissemination of information through social networks and provision of social support will promote screening. The authors prospectively examined the relationship between social network ...
Study data from L. Ayadi et al provide new insights into breast cancer.(Report)
Jan 06, 2009 ... "Breast carcinoma is a disease with a tremendous heterogeneity in its clinical behavior. Newer prognostic factors and predictors of response to therapy are needed," investigators in Sfax, Tunisia report (see also Breast Cancer). "The aim of this study was to evaluate the ...
Study findings on breast cancer are outlined in reports from J.E. Celis and colleagues.
Jan 06, 2009 ... According to a study from Copenhagen, Denmark, "Established histopathological criteria divide invasive breast carcinomas into defined groups. Ductal of no specific type and lobular are the two major subtypes accounting for around 75 and 15% of all cases, respectively." "The ...
Study findings on breast cancer are outlined in reports from University of Hong Kong.(Report)
Jan 06, 2009 ... "Since the introduction of breast-conserving surgery (BCS), it has been increasingly accepted as the standard surgical option for suitable breast cancer patients in Western countries. However, there have been reports suggesting striking ethnic variations in those undergoing BCS," ...
Study results from University of Hong Kong broaden understanding of breast cancer.(Report)
Jan 06, 2009 ... "Breast cancer in young women is uncommon, but when it does occur it has been reported to have aggressive biological characteristics. The incidence of breast cancer peaks at age 40 in Hong Kong Chinese women, earlier than in Caucasians," scientists writing in the World Journal of Surgery ...