Cancer Weekly back issues from April 2009:
Ezetimibe and Ezetimibe/Simvastatin Combo Pose No Increased Cancer Risk, Study Shows.
Apr 07, 2009 ... A new study shows no increased cancer risk with ezetimibe mono and ezetimibe/simvastatin combination treatments, compared to cancer rates of other powerful lipid-lowering statin therapies. The study, conducted by Tufts Medical Center lipid and health policy experts, was published in the ...
Study findings on cancer vaccines are outlined in reports from University of North Carolina.(Report)
Apr 07, 2009 ... According to recent research from the United States, "Differential access to basic health information may contribute to persistent cervical cancer disparities. We examined whether human papillomavirus (HPV) vaccine awareness, HPV knowledge, and use of information sources about the vaccine ...
Cianna Medical Announces Issued Patents for SAVI Multi-Catheter Brachytherapy Device.
Apr 07, 2009 ... Cianna Medical announced that the U.S. Patent and Trademark Office issued two patents that are directly related to its SAVIĀ multi-catheter brachytherapy device for the treatment of breast cancer. The patents, Nos. 7,497,819 and 7,497,820 and titled "Expandable Brachytherapy Device," ...
Fondation Ipsen: 5th Colloque Medecine et Recherche of the Cancer series: "Molecular Targets of Cancer Therapy".
Apr 07, 2009 ... The 5th Colloque Medecine et Recherche in the series Cancer Science of La Fondation Ipsen, took place from February 14th to 18th this year in Jaipur (India) on the theme "Molecular Targets of Cancer Therapy", Each year, the series of meetings brings together the world's top scientific ...
Findings from Seoul National University advance knowledge in gene therapy.
Apr 07, 2009 ... "Myeloid-derived suppressor cells (MDSCs), which are known to be accumulated in the blood, spleen, and bone marrow of tumor-bearing mice and cancer patients, were tested as APCs for a cellular vaccine because they have phenotypical similarity with inflammatory monocytes and may be ...
American Urological Association Statement in Support of Prostate-Specific Antigen Testing.
Apr 07, 2009 ... The statement below is attributable to Dr. John Barry, president of the American Urological Association. This statement is being issued in response to two studies recently published in the New England Journal of Medicine about prostate-specific antigen (PSA) testing (see also ...
Findings from Southern Medical University in adenoma reported.(Report)
Apr 07, 2009 ... "The purpose of this Study was to examine the membranous layers of the human pituitary gland and their relationships with invasive adenomas. Histological and microdissection techniques were used to Study 8 fetal and 10 adult human cadavers, respectively," researchers in Guangzhou, People's ...
Research on amelanotic melanoma reported by scientists at University of Milan.
Apr 07, 2009 ... "Amelanotic melanomas (AM) are a difficult diagnostic challenge for clinicians. To consider the clinical presentation of AM, the histologic subtypes involved, the relationship with the diagnostic delay and the possible involvement in overall prognosis," scientists writing in the Journal of ...
Study results from Chiba University update understanding of apoptosis.(Report)
Apr 07, 2009 ... "Death receptor 5 (DR5) is an apoptosis-inducing membrane receptor for TNF-related apoptosis-inducing ligand ( TRAIL). On screening for compounds that enhance DR5 expression using a luciferase assay with DLD-1/SacI, we previously identified 4'-demethyltoxicarol isoflavone ( 1) isolated ...
Scientists at University of California, Medical Department report research in ataxia telangiectasia.
Apr 07, 2009 ... "The functional consequences of missense variants are often difficult to predict. This becomes especially relevant when DNA sequence changes are used to determine a diagnosis or prognosis," investigators in the United States report (see also Ataxia Telangiectasia). "To analyze ...
Reports summarize autoimmune disease study results from University of Texas.
Apr 07, 2009 ... "Some forms of peripheral autonomic dysfunction (especially enteric neuropathy and subacute panautonomic failure) occur as autoimmune phenomena either in isolation or in the context of cancer," researchers in the United States report (see also Autoimmune Disease). "Autoimmune ...
Researchers from Erasmus University provide details of new studies and findings in the area of basal cell cancer.
Apr 07, 2009 ... According to a study from Rotterdam, Netherlands, "Nevoid basal cell carcinoma syndrome (NBCCS) is characterized by the development of multiple basal cell carcinomas (BCCs). A major problem for these patients is the enormous amount of BCCs which can invade in the deep underlying ...
Boston University details research in biopsy.
Apr 07, 2009 ... According to a study from the United States, "The authors evaluated the effectiveness of the oral brush biopsy technique as a diagnostic tool in detecting dysplastic oral lesions. In this cross-sectional study, pathologic reports (n=152) from the scalpel biopsies (tissue samples) in ...
New findings from R. Pintoleite and co-authors in the area of bladder cancer published.
Apr 07, 2009 ... According to a study from Vila Real, Portugal, "Sirolimus is recently reported to have antitumour effects on a large variety of cancers. The present study was performed to investigate sirolimus's ability to inhibit growth in T24 bladder cancer cells." "T24 bladder cancer cells ...
New research on bladder cancer from W. Chen and co-authors summarized.(Report)
Apr 07, 2009 ... According to recent research from Guangzhou, People's Republic of China, "Our previous study has suggested an oncogenic role of eIF-5A2 in ovarian tumorigenesis. Abnormalities of eIF-5A2 and its clinical/prognostic significance, however, in urothelial carcinoma of the bladder (UC) are ...
Reports from Zhejiang University highlight recent research in bladder cancer.(Report)
Apr 07, 2009 ... "Toll-like receptor 4 (TLR4) was found to be aberrantly expressed in bladder cancer, inducing some genes expression and facilitating tumor progression. Recent data suggest that tumor associated Interleukin-6 (IL-6) correlates with tumor size and grade in bladder cancer," investigators in ...
Studies from University of Florida, Medical Department reveal new findings on bladder cancer.
Apr 07, 2009 ... According to a study from the United States, "Bladder cancer is the fifth most commonly diagnosed malignancy in the United States and one of the most prevalent worldwide. It harbors a probability of recurrence of > 50%; thus, rigorous, long-term surveillance of patients is advocated." ...
New findings from Washington University, Medical Department in the area of bone research published.
Apr 07, 2009 ... "Interferon-gamma (IFN-gamma) has been shown to enhance anti-tumor immunity and inhibit the formation of bone-resorbing osteoclasts. We evaluated the role of IFN-gamma in bone metastases, tumor-associated bone destruction, and hypercalcemia in human T cell lymphotrophic virus type 1-Tax ...
Reports from H. Shen and colleagues advance knowledge in bone research.(Report)
Apr 07, 2009 ... "Retinoic acid (RA), a biologically active derivative of vitamin A, has protective effects against damage caused by H2O2 or oxygen-glucose deprivation in mesangial and PC12 cells. In cultured human osteosarcoma cells, RA enhances the expression of bone morphogenetic protein-7 (BMP7), a ...
Study data from Gaziantep University update knowledge of bone research.(Report)
Apr 07, 2009 ... According to recent research from Gaziantep, Turkey, "This study aimed to analyze three-dimensional (3D) dosimetric data of conventional two-dimensional (2D) palliative spinal bone irradiation using different reference points and treatment plans with respect to the International Commission ...
New brain cancer study findings have been reported by P. Kremer and colleagues.
Apr 07, 2009 ... According to recent research published in the journal Neurosurgery, "The newly developed conjugate 5-aminofluorescein (AFL)-human serum albumin (HSA) was investigated in a clinical trial for fluorescence-guided surgery of malignant brain tumors to assess its efficacy and tolerability. AFL, ...
New findings from J. Novy and co-authors describe advances in brain cancer.
Apr 07, 2009 ... According to a study from Lausanne, Switzerland, "Patients with brain tumors and seizures should be treated with non-enzyme-inducing antiepileptic drugs (AED). Some of the newer drugs seem particularly suited in these patients." "Here we describe our experience with pregabalin ...
Study data from H. Sarin et al provide new insights into brain cancer.
Apr 07, 2009 ... "Effective transvascular delivery of nanoparticle-based chemotherapeutics across the blood-brain tumor barrier of malignant gliomas remains a challenge. This is due to our limited understanding of nanoparticle properties in relation to the physiologic size of pores within the blood-brain ...
Study results from University of California in the area of brain cancer published.(Report)
Apr 07, 2009 ... According to a study from the United States, "In this study we examined by QRT-PCR the mRNA expression of TGF- 1, IGF-1, EGF, FGF-2 and YY1 in human brain tumors." "Our findings introduce YY1, for the first time, as a novel gene implicated in brain gliomatogenesis and meningioma ...
Data from University of Marburg advance knowledge in breast cancer.
Apr 07, 2009 ... According to recent research published in the Journal of Cancer Research and Clinical Oncology, "The goal of the 2008 updated guideline: early detection of breast cancer in Germany is to support physicians as well as healthy and affected women in the decision-making process involved in the ...
Data on breast cancer described by researchers at National Cancer Institute.
Apr 07, 2009 ... In this recent study, researchers in the United States conducted a study "To examine associations between recreational physical activity and quality of life (QOL) in a multiethnic cohort of breast cancer survivors, specifically testing whether associations are consistent across ...
Data on breast cancer discussed by M.L. Kwan and colleagues.
Apr 07, 2009 ... " To determine the association of dietary patterns with cancer recurrence and mortality of early-stage breast cancer survivors. Patients and Methods Patients included 1,901 Life After Cancer Epidemiology Study participants diagnosed with early-stage breast cancer between 1997 and 2000 and ...
Findings from M. Buijs and co-researchers advance knowledge in breast cancer.
Apr 07, 2009 ... In this recent study, researchers in the United States conducted a study "To evaluate the anti-glycolytic effects of 3-BrPA on rats bearing RMT mammary tumors, by determining FDG uptake after intravenous administration of the therapeutic dose. Sixteen rats bearing RMT tumors were treated ...
Investigators at Seoul National University, Medical Department publish new data on breast cancer.(Report)
Apr 07, 2009 ... According to recent research published in the journal Cancer Epidemiology Biomarkers & Prevention, "High-density lipoprotein cholesterol (HDL-C) has been suggested to be associated with breast cancer. However, the roles of HDL-C and hypertriglyceridemia on breast cancer still have been ...
New breast cancer research from C.A.M. Roelen and co-researchers described.
Apr 07, 2009 ... "Most women are diagnosed with breast cancer when they are of working age. How long are breast cancer patients absent? How many of them return to work? ArboNed Occupational Health Services documents sickness absence data of 1 million workers of whom 40% were women," researchers in ...
New breast cancer study findings have been reported by scientists at University of California.
Apr 07, 2009 ... According to a study from the United States, "In some cohort studies, a high-vegetable diet has been associated with greater likelihood of recurrence-free survival in women diagnosed with breast cancer. Carotenoids are obtained primarily from vegetables and fruit and they exhibit ...
New breast cancer study findings recently were reported by researchers at Royal Adelaide Hospital.(Report)
Apr 07, 2009 ... In this recently published article, scientists in Adelaide, Australia conducted a study "To characterise the gastrointestinal toxicities associated with Trastuzumab administration in HER2-overexpressing breast cancer patients. All patients (n = 46) who received Trastuzumab as a single ...
New findings from E.E. Calle and co-authors describe advances in breast cancer.
Apr 07, 2009 ... "Data from large prospective studies are needed to fully characterize the impact of exogenous hormones on breast cancer incidence by type of hormone preparation and histology of the cancer. In a prospective cohort of 67,754 postmenopausal women in the US, 1821 cases of invasive ductal ...
New findings in breast cancer described from Tampere University.
Apr 07, 2009 ... " Postoperative breast irradiation is considered standard after breast-preserving surgery for cancer. We evaluated the efficacy of radiation therapy in the prevention of local recurrence in a patient population that had small-size breast cancer with features that suggested low biologic ...
Recent studies from Osaka University, Medical Department add new data to breast cancer.
Apr 07, 2009 ... "The authors investigated the impact of the genetic polymorphisms cytochrome P450 (CYP) family 2, subfamily D, polypeptide 6, allele *10 (CYP2D6*10) and CYP family 2, subfamily C, polypeptide 19, allele *2,*3 (CYP2C19*2,*3) on disease recurrence in patients with breast cancer who received ...
Reports on breast cancer findings from D. Kanojia and co-researchers provide new insights.
Apr 07, 2009 ... "To date, there have been no tumor biomarkers validated and incorporated into oncologic practice for the early diagnosis of breast cancer. Recently, we showed that sperm-associated antigen 9 (SPAG9), a member of cancer testis (CT) antigen family, is associated with ovarian carcinomas," ...
Reports outline breast cancer research from N. Uhrhammer and colleagues.
Apr 07, 2009 ... "Mutations in DNA repair genes are known for their association with hereditary breast cancer. BRCA1 and BRCA2 are the major genes for high-penetrance familial breast and ovarian cancer, whereas mutations in ATM or Chek2 confer more modest cancer risk," researchers in Clermont-Ferrand, ...
Reports outline breast cancer study findings from K.W. Reeves and colleagues.
Apr 07, 2009 ... According to recent research from the United States, "High percent mammographic breast density is strongly associated with increased breast cancer risk. Though body mass index (BMI) is positively associated with risk of postmenopausal breast cancer, BMI is negatively associated with ...
Research from University of Colorado in breast cancer provides new insights.
Apr 07, 2009 ... "Taxanes are tubulin-targeting agents that are highly active in the treatment of breast cancer. The lack of cross-resistance and limited overlapping toxicities of taxanes with other agents, such as anthracycline, made it possible to incorporate them in the adjuvant treatment of early ...
Research from University of Texas provide new insights into breast cancer.(Report)
Apr 07, 2009 ... According to recent research from the United States, "Although contralateral prophylactic mastectomy (CPM) reduced the risk of contralateral breast cancer in unilateral breast cancer patients, it was difficult to predict which patients were most likely to benefit from the procedure. The ...
Research in the area of breast cancer reported from J. Shen and colleagues.(Report)
Apr 07, 2009 ... According to recent research published in the International Journal of Cancer, "MicroRNA (miRNA) plays an important role in tumorigenesis, but whether miRNA is a cancer predisposition factor or not is still unknown. Considering the fact that miRNA regulates a number of tumor suppressor ...
Research in the area of breast cancer reported from Ocean University of China.(Report)
Apr 07, 2009 ... "Lipocalin 2, an iron binding protein, is abnormally expressed in some malignant human cancers and may play an important role in tumor metastasis. However, the roles of lipocalin 2 in breast cancer formation and metastasis have not been clearly shown," investigators in Qingdao, People's ...
Researchers at University of Oslo release new data on breast cancer.
Apr 07, 2009 ... According to recent research from Oslo, Norway, "Mammographic density is a potentially modifiable risk factor for breast cancer. To what extent mammographic density is a predictor for both hormone receptor-positive and hormone receptor-negative tumors is unclear." "Even less is ...
Researchers from Nanjing Medical University detail findings in breast cancer.
Apr 07, 2009 ... According to recent research from Nanjing, People's Republic of China, "Small, noncoding RNA molecules, called microRNAs (miRNAs), are thought to function as either tumor suppressors or oncogenes. Common single, nucleotide polymorphisms (SNPs) in miRNAs may change their property through ...
Researchers from Thomas Jefferson University detail findings in breast cancer.
Apr 07, 2009 ... "Recently, we reported that human breast cancer-associated fibroblasts show functional inactivation of the retinoblastoma (RB) tumor suppressor and down-regulation of caveolin-1 (Cav-1) protein expression. However, it remains unknown whether loss of Cav-1 is sufficient to confer functional ...
Scientists at Osaka University, Medical Department discuss research in breast cancer.(Report)
Apr 07, 2009 ... According to a study from Suita, Japan, "Centrosome aberration in number and/or size is reportedly often observed in human breast cancer. The aim of this study was to investigate the relationship between centrosome aberration and chromosomal instability as well as the expression of ...
Scientists at University of Pennsylvania publish new data on breast cancer.(Survey)
Apr 07, 2009 ... " Most of the 182,460 women diagnosed with breast cancer in the United States this year will become long-term survivors. Helping these women transition from active treatment to survivorship is a challenge that involves both oncologists and primary care physicians (PCPs)," investigators in ...
Scientists at Wayne State University discuss research in breast cancer.(Report)
Apr 07, 2009 ... According to recent research published in the journal Planta Medica, "Scutellaria is a traditional herbal remedy with potential anti-cancer activity. The purpose of this study was to evaluate anticancer mechanisms of thirteen Scutellaria species and analyze their leaf, stem and root ...
Studies from Chinese University of Hong Kong have provided new data on breast cancer.
Apr 07, 2009 ... According to recent research published in the International Journal of Cancer, "Licorice is the sweet-tasting rhizomes of a bean plant and is quite commonly used in Western countries for culinary purposes, while it is a medicinal herb in China. Many flavonoids have been isolated from ...
Studies from University of Paris in the area of breast cancer published.(Report)
Apr 07, 2009 ... "Pregnancy results in the transfer of stem cells from the fetus to the maternal circulation. These cells are able to migrate and differentiate within various damaged maternal tissues," scientists writing in the International Journal of Cancer report (see also Breast Cancer). ...
Study findings from Tarbiat Modares University broaden understanding of breast cancer.(Report)
Apr 07, 2009 ... In this recent report, researchers in Iran conducted a study "To estimate the penetrance of breast cancer genes I and 2 (BRCA1/BRCA2) specific gene mutations in Iranian women with breast cancer. We conducted this study in the Department of Biostatistics, Tarbiat Modares University, Tehran, ...
Data on cancer described by researchers at Nagasaki University.(Report)
Apr 07, 2009 ... "This study aimed to evaluate serum cytochrome c (cyto-c) levels as a novel role of tumor marker in patients with operable malignant tumors. Serum cyto-c levels and lactate dehydrogenase (LD) activity were measured in a total of 257 cases (232 malignant and 25 benign)," scientists writing ...
Investigators at Lund University have published new data on cancer.
Apr 07, 2009 ... "HAMLET, a complex of partially unfolded a-lactalbumin and oleic acid, kills a wide range of tumor cells. Here we propose that HAMLET causes macroautophagy in tumor cells and that this contributes to their death," scientists in Lund, Sweden report (see also Cancer). "Cell death ...
New cancer data have been reported by researchers at Cleveland Clinic.(Report)
Apr 07, 2009 ... "Due to the large variability in survival times between cancer patients and the plethora of genes on microarrays unrelated to outcome, building accurate prediction models that are easy to interpret remains a challenge. In this paper, we propose a general strategy for improving performance ...
New cancer data have been reported by researchers at University of Waterloo.
Apr 07, 2009 ... According to a study from Waterloo, Canada, "The Canadian Cancer Society's Centre for Behavioural Research and Program Evaluation (CBRPE) is a national asset for building pan-Canadian capacity to support intervention studies that guide population-level policies and programs. This paper ...
New cancer findings from Erasmus University described.
Apr 07, 2009 ... "The costs of computed tomographic colonography (CTC) are not yet established for screening use. In our study, we estimated the threshold costs for which CTC screening would be a cost-effective alternative to colonoscopy for colorectal cancer (CRC) screening in the general population," ...
New cancer research reported from S. Miccadei and co-authors.
Apr 07, 2009 ... "The understanding of cutaneous pigmentation biology is relevant from the biologic and clinical point of view. The binding of alpha-melanocortin and its specific receptor, on the plasma membrane of melanin synthesising cells, plays a crucial role in melanins biosynthesis," researchers in ...
New cancer study findings have been reported by R.T. Zon and colleagues.
Apr 07, 2009 ... According to recent research from the United States, "Oncologists have a critical opportunity to utilize risk assessment and cancer prevention strategies to interrupt the initiation or progression of cancer in cancer survivors and individuals at high risk of developing cancer. Expanding ...
New cancer study findings have been reported by scientists at University of Witten.
Apr 07, 2009 ... According to recent research from Witten, Germany, "Peritoneal carcinomatosis (PC) from epithelial tumors is a fatal diagnosis without efficient treatment. Trifunctional antibodies (trAb) are novel therapeutic approaches leading to a concerted anti-tumor activity resulting in tumor cell ...
New findings from Brigham and Women's Hospital, Medical Department in the area of cancer described.
Apr 07, 2009 ... According to a study from the United States, "Flavonoids may protect against cancer development through several biological mechanisms. However, epidemiologic studies on dietary flavonoids and cancer risk have yielded inconsistent results." "We prospectively investigated the ...
New findings from J. Chubak and co-researchers in the area of cancer described.
Apr 07, 2009 ... "Several studies suggest antidepressant medications can increase prolactin levels. Some, but not all, studies suggest prolactin levels are positively associated with mammographic breast density, an established risk factor for breast cancer," scientists in the United States report (see also ...
New findings from University of Warsaw in the area of cancer published.(Report)
Apr 07, 2009 ... "Recent studies demonstrate that the peptides in the serum of cancer patients that are generated (ex vivo) as a result of tumor protease activity can be used for the detection and classification of cancer. In this paper, we propose the first formal approach to modeling exopeptidase ...
Reports from C.H. Vangils and colleagues advance knowledge in cancer.(Report)
Apr 07, 2009 ... According to recent research published in the journal Cancer Epidemiology Biomarkers & Prevention, "The protective effect of physical activity on breast cancer risk might be mediated by sex hormone levels. In this study, we examined the association between usual physical activity and ...
Reports from M. Makridakis and co-researchers add new data to research in cancer.(Report)
Apr 07, 2009 ... According to a study from Athens, Greece, "Cell line models aid in understanding cancer aggressiveness. The aim of this study was the establishment of a metastatic variant (T24M) of the T24 bladder cancer cell line and its initial characterization at chromosomal and proteomic levels." ...
Reports outline cancer study findings from National Cancer Institute.(Report)
Apr 07, 2009 ... "Barrett's esophagus (BE) is a risk factor for esophageal adenocarcinoma. Modifiable risk factors for BE are largely unknown," researchers in the United States report (see also Cancer). "The purpose of this study was to determine whether vegetable and fruit intakes are ...