Cancer Weekly back issues from May 2009:
Muscadine Grape Skin Dietary Supplement Protects against Cancer Therapy Radiation Side Effects.
May 05, 2009 ... Muscadine grape skin powder, from Muscadine Naturals, Inc, (http://www.muscadinenaturals.com/), provided significant protection against radiation damage in an independent study conducted on mice. The finding was reported in April of 2009 at the 100th Annual Meeting of the American ...
Researchers from University of Pittsburgh, Department of Immunology discuss findings in cancer gene therapy.
May 05, 2009 ... New investigation results, 'Lentiviral vectors encoding human MUC1-specific, MHC-unrestricted single-chain TCR and a fusion suicide gene: potential for universal and safe cancer immunotherapy,' are detailed in a study published in Cancer Immunology, Immunotherapy. "MUC1 tumor antigen is a ...
New data from Yale University illuminate research in hepatitis B virus risk factors.
May 05, 2009 ... Researchers detail in 'Hepatitis B virus infection in US correctional facilities: a review of diagnosis, management, and public health implications,' new data in hepatitis B virus. "Among the blood-borne chronic viral infections, hepatitis B virus (HBV) infection is one that is not only ...
New immunotherapy study findings have been published by scientists at School of Medicine.(Report)
May 05, 2009 ... New research, 'Adoptive transfer of HER2/neu-specific T cells expanded with alternating gamma chain cytokines mediate tumor regression when combined with the depletion of myeloid-derived suppressor cells,' is the subject of a report. According to recent research from the United States, ...
New findings from Federal University, Department of Pathology describe advances in leukemia gene therapy.
May 05, 2009 ... Scientists discuss in 'Adult T-cell leukemia/lymphoma (ATL) presenting in the skin: clinical, histological and immunohistochemical features of 52 cases' new findings in leukemia. According to recent research published in the journal Acta Oncologica, "Adult T-cell leukemia/lymphoma (ATL) is ...
Research from P. Rozen and co-researchers provides new data on adenoma.
May 05, 2009 ... According to recent research from Israel, "Faecal occult blood tests (FOBT) are faulted by low sensitivity for advanced adenomatous polyps (AAP). Quantified, immunochemical, haemoglobin (Hb)-specific immunochemical FOBT (I-FOBT) measurements are now used for colorectal screening." ...
New amyloidosis findings from University of Pavia described.
May 05, 2009 ... "In dialysis-related amyloidosis, beta 2-microglobulin accumulates as amyloid fibrils preferentially around bones and tendons provoking osteoarthritis. In addition to the pathologic role played by the amyloid fibrils, it can be speculated that a pathogenic role is also played by the high ...
New data from I. Oblak et al illuminate research in anal cancer.(Clinical report)
May 05, 2009 ... According to a study from Ljubljana, Slovenia, "Results of radiochemotherapy in 50 patients with squamous cell carcinoma of the anal canal, treated with radical radiochemotherapy between January 2003 and September 2007. at the Institute of Oncology Ljubljana are presented. The treatment ...
Studies from O.P. Erpolat and co-researchers yield new data on angiosarcoma.
May 05, 2009 ... "Primary tumors of the heart are rarely seen. Cardiac angiosarcomas are malignant tumors that almost always have a poor prognosis," scientists in Ankara, Turkey report (see also Angiosarcoma). "We describe a 29-year-old man with primary cardiac angiosarcoma with multiple site ...
New anti-infectives findings from A. Alam and co-authors described.
May 05, 2009 ... According to a study from Solan, India, "Podophyllotoxin and its structural derivatives, a class of tubulin polymerization inhibitors, have been the objective of numerous studies to prepare better and safer anti-cancer drugs. A library of podophyllotoxin analogues has been designed ...
Investigators at Teikyo University target astrocytoma.
May 05, 2009 ... "Interferon beta 6 Million Units per week was administered to a patient with all aggressive astrocytoma in the tectum that was resistant to cisplatin, etoposide, vinblastine, and the oral alkylating agent temozolomide. The tumor was immunopositive for O-6-methylguanine-DNA ...
Data from X.H. Li et al provide new insights into barrett esophagus.
May 05, 2009 ... According to recent research from the United States, "Chromosome copy gain, loss, and loss of heterozygosity (LOH) involving most chromosomes have been reported in many cancers; however, less is known about chromosome instability in premalignant conditions. 17p LOH and DNA content ...
Study data from Y. Huang and co-authors update knowledge of barrett esophagus.
May 05, 2009 ... "The frequency of oesophageal adenocarcinoma is increasing in Western countries for unknown reasons, and correlates with a corresponding increase in the pre-malignant condition, Barrett's Oesophagus, which raises the risk of adenocarcinoma by some 40- to 125-fold. We have examined how ...
Studies from M. Samimi and co-researchers yield new data on biopsy.
May 05, 2009 ... According to a study from Orleans, France, "The study was performed to substantiate the value of detecting clips in mastectomy specimens as a guide to taking pathological samples. We performed a retrospective review of 4 cases of mastectomy required after biopsies of microcalcifications." ...
Scientists at University of California discuss research in bladder cancer.
May 05, 2009 ... According to recent research from the United States, "Flavokawain A is the predominant chalcone from kava extract. We have assessed the mechanisms of flavokawain A's action on cell cycle regulation." "In a p53 wild-type, low-grade, and papillary bladder cancer cell line (RT4), ...
Research on bone cancer described by scientists at Gunma University, Medical Department.
May 05, 2009 ... According to recent research published in the journal Acta Orthopaedica, "Background and purpose The defect that results after curettage of a bone tumor is usually filled in the same way. We report the outcome in patients with benign bone tumors that were treated with curettage but no ...
Studies from Osaka University reveal new findings on brain cancer.
May 05, 2009 ... "Multimodal imaging is one of the necessary steps in the treatment of malignant brain tumors, and use of magnetic resonance imaging (MRI) and positron emission tomography (PET) are the current gold standard technique for the morphological and biological assessment of malignant brain ...
Findings from Cleveland Clinic in breast cancer reported.(Report)
May 05, 2009 ... According to recent research published in the journal Clinical Breast Cancer, "Aromatase inhibitors (AIs) are an effective treatment for postmenopausal women with hormone receptor-positive breast cancer. However, patients receiving AIs report a higher incidence of musculoskeletal symptoms ...
Findings from University of Toledo in breast cancer reported.(Report)
May 05, 2009 ... "The purposes of this study were to assess the sensitivity and specificity of 3-T MRI compared with those of mammography and sonography in the evaluation of breast cancer and to evaluate the results in light of previously published data obtained with 1-T and 1.5-T systems. A retrospective ...
Investigators at State University of New York have published new data on breast cancer.
May 05, 2009 ... "Phenethyl isothiocyanate (PEITC) and sulforaphane (SF) exhibit tumor preventive activity in lung, prostate, breast and colon cancers. Our objective was to examine the effect of these two isothiocyanates on estrogen receptor-related genes, and genes related to apoptosis and cell cycle in ...
Investigators at University of Texas have published new data on breast cancer.
May 05, 2009 ... According to a study from the United States, "In breast tumors, high levels of leptin have been associated with increased incidence of breast cancer metastasis. Breast cancer metastasis is directly associated with breast cancer cell invasion." "However, whether leptin could ...
New breast cancer findings from P. Potemski and co-authors described.
May 05, 2009 ... "Cyclin E is an important regulator of cell-cycle progression. High levels of cyclin E protein in breast cancer have been reported in association with higher disease stage, poor histological differentiation of tumor, and lack of steroid receptors," researchers in Lodz, Poland report (see ...
New breast cancer study findings have been published by scientists at Queensland University of Technology.
May 05, 2009 ... According to recent research from Brisbane, Australia, "HAYES, S. C., I I. RFUL-HIRCHE,and J. TURNER. Exercise and Secondary Lymphedema: Safety, Potential Benefits, and Research Issues. Med." "Sci Sports Exetc., Vol. 41, No. 3, pp. 483-489, 2009. Participating in regular ...
New breast cancer study findings have been reported by researchers at University of California, Medical Department.
May 05, 2009 ... According to recent research from the United States, "The role of diet as a cause of breast cancer in Asian Americans has not been adequately studied. We investigated the association between dietary patterns and breast cancer risk in Asian Americans." "This population-based ...
New breast cancer study findings have been reported by researchers at University of Wisconsin.
May 05, 2009 ... "The purpose of our study was to create a breast cancer risk estimation model based on the descriptors of the National Mammography Database using logistic regression that can aid in decision making for the early detection of breast cancer. We created two logistic regression models based on ...
New breast cancer study findings recently were reported by K. Pande and co-researchers.
May 05, 2009 ... "Intravascular delivery (1.5 x 10(9) particles and higher) of recombinant adenovirus (rAd) induces myeloid cell mediated, self-limiting hemodynamic responses in normal mice. However, we observed anaphylactoid-type reactions and exacerbated hemodynamic events following rAd injection in mice ...
New findings from Q. He and co-researchers in the area of breast cancer described.(Report)
May 05, 2009 ... According to recent research from Xian, People's Republic of China, "Breast carcinoma (BC) is a prevalent malignant tumour occurring in women. Many studies have indicated the role of human papilloma virus type 16 (HPV16) in the pathogenesis of BC; however, the correlations of HPV16 ...
Recent findings in breast cancer described by researchers from Princess Margaret Hospital.
May 05, 2009 ... "Clinical experience suggests that many women with triple-negative metastatic breast cancer (MBC) relapse quickly. This has implications for clinical practice and trial design," researchers in Toronto, Canada report (see also Breast Cancer). "We evaluated the duration of first-, ...
Reports from C.H. Wan and co-researchers add new data to research in breast cancer.
May 05, 2009 ... "To develop and validate a quality of life (QOL) instrument for patients with breast cancer, QLICP-BR, which is one of the system of QOL instruments for cancer patients in China. Using the programmed decision methods of instrument development, the quality of life instrument for cancer ...
Reports outline breast cancer research from University of Jena.(Report)
May 05, 2009 ... According to a study from Jena, Germany, "In breast cancers, the gene for the growth factor receptor HER2 can be amplified leading to increased aggressiveness and metastasis formation. The monoclonal antibody trastuzumab prolongs relapse-free survival highly significantly but eventually ...
Reports outline breast cancer study findings from W. Zhou and colleagues.
May 05, 2009 ... According to recent research from Jinan, People's Republic of China, "Epithelial membrane protein 3 (EMP3) is a trans-membrane signaling molecule with important roles in the regulation of apoptosis, differentiation and invasion of cancer cells, but the detailed is largely still unknown. We ...
Research conducted by S.M. Campos and co-researchers has updated our knowledge about breast cancer.(Report)
May 05, 2009 ... "Patients developing visceral breast cancer metastases generally receive chemotherapy rather than endocrine therapy. Recent aromatase inhibitor studies have reported activity in such patients; therefore, this study formally evaluated anastrozole and exemestane in postmenopausal patients in ...
Research findings from University of Tsukuba update understanding of breast cancer.
May 05, 2009 ... According to recent research from Tsukuba, Japan, "CHIP is a U-box-type ubiquitin ligase that induces ubiquitylation and degradation of its substrates, which include several oncogenic proteins(1-12). The relationship between CHIP and tumour progression, however, has not been elucidated." ...
Research from M.M. Gaudet and co-researchers yields new findings on breast cancer.(Report)
May 05, 2009 ... According to a study from the United States, "Genetic variation in SIPA1, signal-induced proliferation-associated gene 1, has been proposed to be associated with aggressive breast tumor characteristics related to metastasis and worse prognosis in humans and rodents. To test this ...
Research from R.E. Ellsworth et al broadens understanding of breast cancer.
May 05, 2009 ... "The most important predictor of prognosis in breast cancer is lymph node status, yet little is known about molecular changes associated with lymph node metastasis. Here, gene expression analysis was performed on primary breast (PBT) and corresponding metastatic lymph node (MLN) tumors to ...
Research from University of Zagreb yields new data on breast cancer.
May 05, 2009 ... "Aims and background. Recent publications of breast cancer classification based on gene expression profile analyses indicate that medullary breast carcinomas (MBC) may be considered part of the basal-like carcinoma spectrum made lip of ER-negative, PR- negative and HER-2-negative cells ...
Research reports from J.J. Fu and co-authors provide new insights into breast cancer.
May 05, 2009 ... According to recent research from Shanghai, People's Republic of China, "Androgen receptor (AR) plays a critical role in development and maintenance of male reproductive functions and the etiology of prostate cancer. As a ligand-regulated transcription factor, identification and ...
Researchers from Mayo Clinic report on findings in breast cancer.(Report)
May 05, 2009 ... "The high sensitivity and lower specificity of breast MRI for detecting breast cancer are well documented in the literature. As the use of breast MRI continues to grow, medical controversy persists over the appropriate use of this test," scientists writing in the American Journal of ...
Researchers from Northwestern University publish new studies and findings in the area of breast cancer.
May 05, 2009 ... "Effective methods of serial epithelial sampling to measure breast-specific biomarkers will aid the rapid evaluation of new preventive interventions. We report here a proof-of-principle phase 2 study to assess the utility of ductal lavage (DL) to measure biomarkers of tamoxifen action," ...
Researchers from University of British Columbia discuss findings in breast cancer.
May 05, 2009 ... "The tumor-tropic properties of neural stem cells (NSCs) led to the development of a novel strategy for delivering therapeutic genes to tumors in the brain. To apply this strategy to the treatment of brain metastases, we made a human NSC line expressing cytosine deaminase (F3," scientists ...
Scientists at University of California describe research in breast cancer.
May 05, 2009 ... "We demonstrate successful treatment of recurrent chondroid-metaplastic breast cancer. Breast cancer recurrence was diagnosed when a patient with a history of metaplastic breast cancer presented with recurrent acute strokes," scientists writing in the journal Clinical Breast Cancer report ...
Scientists at University of Texas publish new data on breast cancer.
May 05, 2009 ... According to recent research from the United States, "The intraoperative evaluation of axillary sentinel lymph nodes (SLNs) allows the surgeon to complete axillary dissection in I setting at the time of the primary breast surgery. However, to the authors' knowledge, there is no consensus ...
Studies conducted at National University on breast cancer recently published.
May 05, 2009 ... "Patients with breast cancer often receive emetogenic anthracycline-based chemotherapy as part of their treatment. Chemotherapy-induced nausea and vomiting (CINV) has been commonly reported as one of the distressing adverse effects among patients with cancer," investigators in Singapore, ...
Studies from N.P. Tang et al provide new data on breast cancer.
May 05, 2009 ... "This metaanalysis was conducted to assess the association between coffee consumption and breast cancer risk. Relevant studies were identified by searching Medline (1966-May 2008) and the reference lists of retrieved articles," investigators in Shanghai, People's Republic of China report ...
Studies from S.F. Sener et al provide new data on breast cancer.(Report)
May 05, 2009 ... "The goal of this study was to compare the characteristics of breast cancers and survival rates in HRT users versus nonusers. Data were analyzed for 1055 patients 2:50 years of age who had definitive therapy for breast cancer from 1994 through 2002," scientists writing in the American ...
Studies from V.G. Vogel and colleagues yield new information about breast cancer.
May 05, 2009 ... "Postmenopausal women with osteoporosis had a 66% relative risk reduction for invasive breast cancer over 8 years of raloxifene therapy in the randomized, placebo-controlled 4-year MORE (Multiple Outcomes of Raloxifene Evaluation) trial and the CORE (Continuing Outcomes Relevant to Evista) ...
Studies from Y.S. Lobanova et al have provided new data on breast cancer.
May 05, 2009 ... According to a study from Russia, "The progression of breast cancer cells to estrogen-independent growth may be accompanied with the paradoxical cell sensitization to estrogen apoptotic action; however, the mechanism of this phenomenon is still unclear. In the present study, we have shown ...
Study findings on breast cancer are outlined in reports from C.D. Britten and colleagues.
May 05, 2009 ... "This phase I/II trial was conducted to determine the toxicities, recommended dose, pharmocokinetics, and response rate of erlotinib plus trostuzumob in metastatic HER2+ breast cancer. In phase I, sequential groups of patients with unlimited previous treatment received erlotinib at dose ...
New breast cancer screening study findings have been reported by researchers at University of Cape Town.
May 05, 2009 ... According to a study from Observatory, South Africa, "This paper presents a mathematical tissue-equivalent breast phantom for linear slot-scanning digital mammography." "A recently developed prototype linear slot-scanning digital mammography system was used for model validation; ...
Research from Siemens AG in the area of breast cancer screening published.
May 05, 2009 ... In this recently published study, investigators in Erlangen, Germany conducted a study "To investigate the average glandular dose (AGD) applied for clinical digital mammograms acquired with the anode/filter combinations molybdenum/molybdenum (Mo/Mo), molybdenum/rhodium (Mo/Rh), and ...
Study findings from I.A. Elbakri et al provide new insights into breast cancer screening.
May 05, 2009 ... According to recent research from Winnipeg, Canada, "We investigated the physical characteristics of two complementary metal oxide semiconductor (CMOS) mammography detectors. The detectors featured 14-bit image acquisition, 50 mu m detector element (del) size and an active area of 5 cm x 5 ...
Researchers at Dokuz Eylul University, Medical Department target breast disease.
May 05, 2009 ... According to recent research published in the journal Biological Trace Element Research, "Gross cystic breast disease (GCBD) is one of the most common breast diseases, and women with apocrine (type I) cysts are at higher risk of developing breast cancer than women with flattened (type II) ...
Data on cancer detailed by D.F. Merlo and co-authors.(Obituary)
May 05, 2009 ... "Aims and background. An unconventional cancer treatment known as ''Di Bella multitherapy'' gained popularity among Italian cancer patients during the 90's," investigators in Genoa, Italy report (see also Cancer). "In 1999, it was shown to lack any detectable antitumor ...
Data on cancer discussed by researchers at Medical College.
May 05, 2009 ... "Nowadays China has the largest population in the world. A recent epidemiology investigation has shown that cancer is the main cause of mortality, ahead of heart and cerebrovascular diseases," scientists in Harbin, People's Republic of China report (see also Cancer). "However, ...
Data on cancer published by researchers at University of California.
May 05, 2009 ... According to a study from the United States, "The intent of this study was to examine supportive care needs and preferences among young adult cancer survivors. Eight hundred seventy-nine young adults aged 18-39 years at time of study and diagnosed with cancer between the ages of 15-35 ...
Findings in cancer reported from University of British Columbia.
May 05, 2009 ... According to a study from Vancouver, Canada, "Mutations that cause chromosome instability (CIN) in cancer cells produce ''sublethal'' deficiencies in an essential process (chromosome segregation) and, therefore, may represent a major untapped resource that could be exploited for ...
Investigators at Kurume University, Medical Department have published new data on cancer.
May 05, 2009 ... According to a study from Fukuoka, Japan, "Limited information is available regarding the usefulness of third-line chemotherapy for recurrent ovarian, fallopian tube, and primary peritoneal cancer treated with platinum-taxane regimens as first-line therapy. We retrospectively reviewed the ...
New cancer data have been reported by researchers at University of Milan.(Clinical report)
May 05, 2009 ... "The objective of the study was to evaluate the prevalence of cancer and premalignant lesions in polyps on atrophic endometrium in asymptomatic postmenopausal women to compare these findings with a similar cohort of patients with abnormal uterine bleeding. One thousand one hundred ...
New cancer research has been reported by scientists at University of Waterloo.(Report)
May 05, 2009 ... According to recent research from Waterloo, Canada, "Cancer is primarily a chronic disease of older adults that must be managed and incorporated into everyday activities. Online sites are important sources of health care information and support." "Health literacy is necessary ...
New cancer study findings have been published by A.E. Hirsch and colleagues.
May 05, 2009 ... According to a study from the United States, "The Oncology Education Initiative was created to advance oncology and radiation oncology education by integrating structured didactics into the existing core radiology clerkship. We set out to determine whether the addition of structured ...
New cancer study findings have been reported by researchers at University of California.
May 05, 2009 ... "Nonsteroidal anti-inflammatory drugs (NSAID) have been associated with adverse cardiovascular (CV) outcomes in cancer prevention and other clinical trials. A recent meta-analysis suggested that baseline CV risk is associated with NSAID-associated adverse CV events," scientists writing in ...
New cancer study findings reported from Erasmus University.
May 05, 2009 ... According to recent research published in the journal Human Reproduction, "The aim was to assess possible treatment-induced gonadal damage in a cohort of adult female childhood cancer survivors (CCS) using anti-Mullerian hormone (AMH), the most sensitive marker of ovarian reserve. A total ...
New cancer study results reported from Stanford University, Medical Department.
May 05, 2009 ... "The Hedgehog (Hh) signaling pathway controls growth, cell fate decisions, and morphogenesis during development. Damage to Hh transduction machinery can lead to birth defects and cancer," scientists writing in the journal Proceedings of the National Academy of Sciences of the United States ...
New data from M. Vossenaar et al illuminate research in cancer.(Report)
May 05, 2009 ... "The 1997 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) Report provides individual guidelines to reduce global cancer risk. The positive deviance approach could be appropriate for creating class-appropriate, healthy eating menu guides for consuming a diet to ...
New data from Massachusetts General Hospital illuminate research in cancer.(Report)
May 05, 2009 ... According to a study from the United States, "The objective of our study was to evaluate a large cohort of patients with PET/CT to determine whether qualitative (visual) assessment, quantitative standardized uptake value (SUV), or standardized uptake ratio (SUR) techniques should be used ...