Climacteric back issues from June 2006:
Does retention of the ovaries improve long-term survival after hysterectomy? The validity of the epidemiological evidence
Jun 01, 2006; ... Key words: RETENTION OF OVARIES, HYSTERECTOMY, LONG-TERM SURVIVAL ABSTRACT Based on a decision analysis of multiple epidemiological studies, it has been claimed that, among women hysterectomized for benign disease, removal of the ovaries before the age of 65 years decreases ...
The use and abuse of screening tests around menopause
Jun 01, 2006; ... 'Listen carefully to the patient, take a good history and examine her. Then you will need few, if any, diagnostic tests to determine the correct diagnosis and treatment.' 'Don't order a test if it is not going to change your management.' 'Unnecessary tests create unnecessary costs, unnecessary ...
Does retention of the ovaries improve long-term survival after hysterectomy? A gynecological oncological perspective
Jun 01, 2006; ... Key words: RETENTION OF OVARIES, LONG-TERM SURVIVAL, HYSTERECTOMY ABSTRACT Ovarian cancer is, in most cases, a lethal disease as it is virtually impossible to diagnose at an early stage and almost impossible to treat successfully when detected at an advanced stage. In ...
Does retention of the ovaries improve long-term survival after hysterectomy? Prophylactic oophorectomy
Jun 01, 2006; ... Key words: PROPHYLACTIC OOPHORECTOMY, HORMONE REPLACEMENT THERAPY, OVARIAN CANCER, HYSTERECTOMY ABSTRACT The controversy surrounding prophylactic oophorectomy is discussed. The importance of adequate hormone replacement with estradiol and particularly testosterone is discussed as ...
Adipose tissue, insulin resistance and low-grade inflammation: implications for atherogenesis and the cardiovascular harm of estrogen plus progestogen therapy
Jun 01, 2006; ... Key words: OBESITY, BODY FAT DISTRIBUTION, ADIPONECTIN, CARDIOVASCULAR RISKS, HORMONE THERAPY, POSTMENOPAUSAL WOMEN ABSTRACT Objective To summarize recent findings providing mechanistic insight into why the relative presence of central to peripheral fat mass is a critical ...
Depressed mood symptoms during the menopausal transition: observations from the Seattle Midlife Women's Health Study
Jun 01, 2006; ... Key words: DEPRESSED MOOD, MENOPAUSAL TRANSITlON, DYSPHORIA, MENSTRUAL CYCLE, SYMPTOMS ABSTRACT Aim To describe patterns of depressed mood during the menopausal transition (MT) and to investigate relationships between patterns of depressed mood and MT stages. Methods ...
No differences in performance on test of working memory and executive functioning between healthy elderly postmenopausal women using or not using hormone therapy
Jun 01, 2006; ... Key words: POSTMENOPAUSE, HORMONE THERAPY, WORKING MEMORY, EXECUTIVE FUNCTIONS, NEUROPSYCHOLOGICAL TESTS ABSTRACT Background On average, ovarian function ceases at the age of 52 years so that estrogen (E) levels are chronically low following the menopause. Numerous studies have ...
Differential prevalence of quality-of-life categories (domains) in Asian women and changes after therapy with three doses of conjugated estrogens/medroxyprogesterone acetate: the Pan-Asia Menopause (PAM) study
Jun 01, 2006; ... Key words: MENOPAUSE, PAN-ASIA MENOPAUSE STUDY, PAM STUDY, ASIAN WOMEN, HORMONE THERAPY, QUALITY OF LIFE, MENQOL ABSTRACT Objectives To assess the prevalence of four categories (domains) of menopausal symptoms as markers for quality of life in nine ethnic groups of Asian women ....
Villous papyraceous: an unusual cause of tamoxifen-induced postmenopausal bleeding
Jun 01, 2006; ... Key words: TAMOXIFEN, POSTMENOPAUSAL BLEEDING, CHORIONIC VILLI, TROPHOBLAST, β-HUMAN CHORIONIC GONADOTROPIN ABSTRACT Objective We describe an unusual histological finding in a woman with postmenopausal bleeding who was being treated with tamoxifen for breast ...
Algorithm for prescription of HRT or ERT for postmenopausal women
Jun 01, 2006; ... Results of the Women's Health Initiative (WHI) indicated that estrogen plus progestin therapy (HRT) but not replacement with estrogen alone (ERT) promotes cardiovascular harm in post-menopausal women initiating therapy about 15 years after menopause1,2. Consequently, we may expect that a high ...
Moderate dosage estrogen-androgen therapy improves continuation rates in postmenopausal women: impact of the WHI reports
Jun 01, 2006; ... Key words: POSTMENOPAUSAL, MODERATE-DOSAGE HRT, CONTINUATION RATES ABSTRACT Objective The purpose of this report is not to provide descriptive data for practice recommendations but to point the way to more liberal thinking than the conservatism of today. The patients in this ...
ER[beta] scientific visions translate to clinical uses
Jun 01, 2006; ... Key words: AUTOIMMUNE DISEASES, ENDOMETRIOSIS, DEPRESSION, HYPERTENSION, ERβ AGONIST ABSTRACT Estrogen receptor β (ERβ) was discovered in 1995 and reported on in 1996. During the 10 years following this event, our understanding of estrogen signaling has changed ...
Evidence for associations between common polymorphisms of estrogen receptor [beta] gene with homocysteine and nitric oxide
Jun 01, 2006; ... Key words: SINGLE NUCLEOTIDE POLYMORPHISM, ESTROGEN RECEPTOR, HOMOCYSTEINE, ASYMMETRIC DIMETHYLARGININE, NITRIC OXIDE ABSTRACT Background Homocysteine and asymmetric dimethylarginine (ADMA) affect nitric oxide (NO) concentration, thereby contributing to cardiovascular disease ...