Functional Neurology

78 total articles

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The effects of botulinum toxin in spasticity and headaches: a common key?

Apr 01, 2008; Sandrini, Giorgio; Tassorelli, Cristina ... Botulinum toxin is considered the best approach in the pharmacological treatment of spasticity. Its use is particularly indicated in patients in whom overactivity of selected muscles at the level of the upper and/or lower limb is detectable. In lower limb spasticity after stroke, different ...

Acute treatment of migraine in children and adolescents

Apr 01, 2008; Termine, Cristiano; Ferri, Matteo; Balottin, Umberto ... Summary The management of headaches with juvenile onset presents several problems, related not only to appropriate drug selection but also to the specific features distinguishing headache disorders in children and adolescents: a child is not a "little adult". Many age-related factors ...

Cerebral blood flow changes in patients with probable medication-overuse headache

Apr 01, 2008; Savrun, Feray Karaali; Goksan, Baki; Savrun, Mert; Sahin, Rahsan; Sahin, Sevki ... Summary Transcranial Doppler (TCD) is a non-invasive method for measuring blood flow velocity (BFV), and a marker of vessel diameter. In this study, intracranial BFV was investigated, by means of TCD, in patients suffering from probable medication-overuse headache ...

Tension-type headache. Comparison with migraine without aura and cervicogenic headache. The Vågå study of headache epidemiology

Apr 01, 2008; Sjaastad, Ottar; Bakketeig, Leiv Sigmund ... Summary The aim of the present study was to describe the prevalence of tension-type headache (T-TH) in rural Norway, and 1838 citizens aged 18-65 years were included. Features indicating neck involvement were also looked for. T-TH was compared with migraine without aura and with ...

Cerebrospinal fluid neuron-specific enolase: a further marker of Alzheimer's disease?

Apr 01, 2008; Palumbo, Barbara; Siepi, Donatella; Sabalich, Isabella; Tranfaglia, Cristina; Parnetti, Lucilla ... Summary To investigate whether neuron-specific enolase (NSE) plays a role in dementia, we measured cerebrospinal fluid (CSF) concentrations of NSE, Abeta42 and total protein tau (h-tau) in different dementia patients. We studied 159 patients: 76 with Alzheimer's disease (AD), 35 with ...

Plasma melatonin pattern in chronic and episodic headaches. Evaluation during sleep and waking

Apr 01, 2008; Bruera, Osvaldo; Sances, Grazia; Leston, Jorge; Levin, Gloria; Cristina, Silvano; Medina, Carlos; Barontini, Marta; Nappi, Giuseppe; de Lourdes Figuerola, María ... Summary To look for a relationship between pineal function in chronic migraine (CM), cluster headache (CH) (during active and remission periods), chronic tension-type headache (CTTH) patients and controls during NREM sleep, REM sleep and waking, we performed serial sampling of plasma ...

Oxcarbazepine and adverse events: impact of age, dosage, metabolite serum concentrations and concomitant antiepileptic therapy

Apr 01, 2008; Ortenzi, Andrea; Paggi, Aldo; Foschi, Nicoletta; Sabbatini, Deborah; Pistoli, Emore ... Summary The aim of this study was to investigate the relationships between oxcarbazepine (OXC) dosage, metabolite mono-hydroxy-derivative (MHD) serum concentrations, number of concomitant antiepileptic drugs, age and incidence of adverse events (AEs) in epileptic patients. A ...

Combined effects of botulinum toxin and casting treatments on lower limb spasticity after stroke

Apr 01, 2008; Farina, Simona; Migliorini, Claudia; Gandolfi, Marialuisa; Bertolasi, Laura; Casarotto, Matteo; Manganotti, Paolo; Fiaschi, Antonio; Smania, Nicola ... Summary Optimal treatment of spasticity requires a combination of pharmacotherapy and muscle lengthening. We evaluated 13 stroke patients with equinovarus foot randomized to treatment with either botulinum toxin A (BTA) injection plus ankle-foot casting (n=6) or BTA alone (n=7). The ...


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