Recently added articles from Genetics:
Point Mutation Rate of Bacteriophage [Phi]X174
Oct 01, 2009; ... ABSTRACT The point mutation rate of phage ΦX174 was determined using the fluctuation test. After identifying the genetic changes associated with the selected phenotype, we obtained an estimate of 1.0 × 10^sup -6^ substitutions per base per round of copying, which is consistent with ...
The Fitness Cost of Streptomycin Resistance Depends on rpsL Mutation, Carbon Source and RpoS ([sigma]^sup S^)
Oct 01, 2009; ... ABSTRACT Mutations that cause antibiotic resistance often produce associated fitness costs. These costs have a detrimental effect on the fate of resistant organisms in natural populations and could be exploited in designing drugs, therapeutic regimes, and intervention strategies. The ...
Nonmetric Multidimensional Scaling Corrects for Population Structure in Association Mapping With Different Sample Types
Jul 01, 2009; ... ABSTRACT Recent research has developed various promising methods to control for population structure in genomewide association mapping of complex traits, but systematic examination of how well these methods perform under different genetic scenarios is still lacking. Appropriate methods ...
Linkage Disequilibrium Between Loci With Unknown Phase
Jul 01, 2009; ... ABSTRACT Linkage disequilibrium is often measured by two statistics, D and r, which can be interpreted as the covariance and the correlation between loci and across gametes. When data consist of diploid genotypes, however, gametes cannot be identified. A variety of iterative statistical ...
The nsdC Gene Encoding a Putative C^sub 2^H^sub 2^-Type Transcription Factor Is a Key Activator of Sexual Development in Aspergillus nidulans
Jul 01, 2009; ... ABSTRACT The formation of the Aspergillus nidulans fruiting body is affected by a number of genetic and environmental factors. Here, the nsdC (never in sexual development) gene-encoding a putative transcription factor carrying a novel type of zinc-finger DNA-binding domain consisting of ...