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Recently added articles from Genome Biology (Online Edition):

Parallel RNAi screens across different cell lines identify generic and cell type-specific regulators of actin organization and cell morphology.(Research)(RNA interference)(Report)

Mar 05, 2009; ... <Text rich="yes"> Authors: Tao Liu [1]; David Sims [2]; Buzz Baum (corresponding author) [1]BackgroundA diversity of cell shapes is a fundamental feature of multicellular life. Cell type-specific forms arise during development as the products of a cell ...

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome.(Software)(http://bowtie.cbcb.umd.edu)(Report)

Mar 04, 2009; ... <Text rich="yes"> Authors: Ben Langmead (corresponding author) [1]; Cole Trapnell [1]; Mihai Pop [1]; Steven L Salzberg [1]RationaleImprovements in the efficiency of DNA sequencing have both broadened the applications for sequencing and dramatically increased the size ...

PEMer : a computational framework with simulation-based error models for inferring genomic structural variants from massive paired-end sequencing data.(Software)(http://sv.gersteinlab.org/pemer)(Report)

Feb 23, 2009; ... <Text rich="yes"> Authors: Jan O Korbel (corresponding author) [1,2,3]; Alexej Abyzov [3]; Xinmeng Jasmine Mu [4]; Nicholas Carriero [5]; Philip Cayting [3]; Zhengdong Zhang [3]; Michael Snyder [3,4]; Mark B Gerstein [3,4,5,6]RationaleFollowing the sequencing of the ...

Widespread evidence for horizontal transfer of transposable elements across Drosophila genomes.(Research)(Report)

Feb 18, 2009; ... <Text rich="yes"> Authors: Carolina Bartolomé [1]; Xabier Bello [1]; Xulio Maside (corresponding author) [1]BackgroundTransposable elements (TEs) are short DNA sequences (usually <15 kb) that behave as intragenomic parasites, vertically transmitted through generations ...

Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum.(Research)(Report)

Feb 13, 2009; ... <Text rich="yes"> Authors: Neekesh V Dharia [1]; Amar Bir Singh Sidhu [2,3]; María Belén Cassera [4]; Scott J Westenberger [1]; Selina ER Bopp [1]; Rich T Eastman [2]; David Plouffe [5]; Serge Batalov [5]; Daniel J Park [6]; Sarah K Volkman [7,8]; Dyann F Wirth [6,7]; Yingyao Zhou [5]; ...