Recently added articles from Gynecological Endocrinology:
Sex, fat and breast cancer
Jan 01, 2009; ... The worldwide incidence of obesity is now recog- nized to be of pandemic proportions. Obesity is associated with a number of clinical conditions including type 2 diabetes, cardiovascular problems and cancer. There is now good epidemiological evidence to indicate that obese women are at increased ...
Adverse effects of excessive ovarian response on the pregnancy rate of in vitro fertilization treatment
Jan 01, 2009; ... In vitro fertilization-embryo transfer (IVF-ET) is an effective treatment for various causes of infertility. Ovarian stimulation is being used in the majority of assisted reproduction units in order to improve the success rate by increasing the number of oocytes and thus embryos available for ...
Mayer-Rokitansky-Kuster-Hauser syndrome: Recent clinical and genetic findings
Jan 01, 2009; ... Abstract Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome is characterized by Müllerian duct aplasia in an XX individual with female phenotype presenting primary amenorrhea at adolescence. Multiple abnormalities may be associated with the MRKH syndrome. Genetic investigations focused on ...
Testosterone replacement therapy in the climacteric: Benefits beyond sexuality
Jan 01, 2009; ... Abstract Testosterone therapy during menopause has a wide range of benefits that reach beyond the realm of human sexuality. This is a consequence not only of the widespread distribution of androgen receptors in various extragonadal tissues but also of the conversion of androgens to ...
Cimicifuga racemosa treatment and health related quality of life in post-menopausal Spanish women
Jan 01, 2009; ... Abstract Objective. The effect of Cimicifuga racemosa (CR) treatment was evaluated in healthy symptomatic post-menopausal women using the Cervantes health-related quality of life (HR-QoL) scale. Design. A prospective observational study was carried out in 122 healthy symptomatic ...
Relationship between serum adipocytokine levels and metabolic syndrome in menopausal women
Jan 01, 2009; ... Abstract Objective. Adipocytokines are bioactive substances derived from adipose tissues, especially visceral fat, and play a crucial role in the development of metabolic syndrome. The aims of this study were to estimate serum levels of adipocytokines (adiponectin, resistin and ...
Effects of phytoestrogens genistein and daidzein on progesterone and estrogen (estradiol) production of human term trophoblast cells in vitro
Jan 01, 2009; ... Abstract Objective. Phytoestrogens are a diverse group of nonsteroidal plant compounds that occur naturally in many plants. Because they possess a ring system similar to estrogens they are able to bind on estrogen receptors alpha and beta in humans. The effects of the phytoestrogens ...
The role of iron in the pathogenesis of endometriosis
Jan 01, 2009; ... Abstract Background. Endometriosis may cause symptoms including chronic pelvic pain and infertility, and increases susceptibility to the development of ovarian cancer. Genomic studies have started to delineate the wide array of mediators involved in the development of endometriosis ....
Low-dose human chorionic gonadotropin during the proliferative phase may adversely affect endometrial receptivity in oocyte recipients
Jan 01, 2009; ... Abstract The effect of low-dose human chorionic gonadotropin (hCG) administration in the proliferative phase of oocyte recipients was investigated in a prospective randomized trial. Sibling oocytes from the same donor were shared at random among two different recipients. In group I ...
Triggering with HCG or GnRH agonist in GnRH antagonist treated oocyte donation cycles: a randomised clinical trial
Jan 01, 2009; ... Abstract Aim. To compare donor and recipient outcome after inducing the final oocyte maturation with hCG or GnRH agonist in GnRH-antagonist treated oocyte donation (OD) cycles. Methods. Two-hundred fifty-seven oocyte donors were enrolled to participate in a clinical trial in a private ...
Recurrent miscarriages: What is the role of cytokines?
Dec 01, 2008; ... Abstract Recurrent miscarriage is defined as three or more consecutive miscarriages before 20 weeks of gestation. This condition is a frequent reproductive problem worldwide, affecting up to 1% of couples. Immune effector cell dysfunction has been implicated in the pathogenesis of early ...
Shorter CAG repeats in the androgen receptor gene may enhance hyperandrogenicity in polycystic ovary syndrome
Dec 01, 2008; ... Abstract Background. The main goal of the present study was to assess the influence of the androgen receptor gene CAG repeat polymorphism on hyperandrogenism and its phenotypical features in patients with polycystic ovary syndrome (PCOS). Methods. CAG repeat lengths were analyzed ...
Effects of estrogen therapy on microalbuminuria in healthy post-menopausal women
Dec 01, 2008; ... Abstract Objective. To evaluate the impact of estrogen therapy on microalbuminuria levels in healthy post-menopausal women. Methods. Sixty post-menopausal women were evaluated in a prospective, randomised, double-blind, placebo-controlled study. The patients were randomly ...
Effects of early luteal-phase vaginal progesterone supplementation on the outcome of in vitro fertilization and embryo transfer
Dec 01, 2008; ... Abstract Objective. To determine whether early luteal-phase vaginal progesterone supplementation improves the outcome of in vitro fertilization-embryo transfer (IVF-ET). Methods. A randomized, controlled trial was conducted on 197 women undergoing IVF-ET cycles with human ...
Levonorgestrel-releasing intrauterine system: why do some women dislike it?
Dec 01, 2008; ... Abstract Background. There is growing evidence of women's dissatisfaction with the levonorgestrel-releasing intrauterine system (LNG-IUS) because of a high incidence of adverse effects. Objective. To quantify the continuation rate and users' satisfaction, and identify symptoms ...
Effect of androgens combined with hormone therapy on quality of life in post-menopausal women with sexual dysfunction
Dec 01, 2008; ... Abstract Aim. To evaluate with validated instruments changes in quality of life and sexuality in women receiving hormonal replacement therapy (AHT). Design. Randomised, double-blind, double-dummy study with two parallel treatment arms. Patients and methods. Forty-seven ...
Coronary heart disease and HRT in France: MISSION study prospective phase results
Dec 01, 2008; ... Abstract Objective. To determine the morbidity incidence associated with Hormone Replacement Therapy (HRTs) in postmenopausal women. This paper presents the results concerning the incidence of coronary heart disease (CHD). Design. MISSION study started on 5 January 2004, the ...
A pilot study on the usefulness of body mass index and waist hip ratio as a predictive tool for gestational diabetes in Asian Indians
Dec 01, 2008; ... Abstract Gestational diabetes mellitus (GDM) is a common public health issue of pregnancy and women who have had GDM are at high risk for developing of diabetes mellitus Type-2. The aim of this study was to find the association between various clinical and biochemical parameters and GDM ....
A novel mutation in exon8 of the follicle-stimulating hormone receptor in a woman with primary amenorrhea
Dec 01, 2008; ... Abstract The FSH receptor (FSHR) gene mutation are rare, but recendy have been detected in several cases with primary amenorrhea. We report a 25-year-old female who had primary amenorrhea, moderately developed secondary sex characteristics and normal sized ovaries with small antral ...
Molecular identification of chromosome Y sequences in Brazilian patients with Turner syndrome
Dec 01, 2008; ... Abstract The investigation of Y-specific sequences in patients with Turner Syndrome (TS) with karyotype 45,X or mosaic, has a fundamental role in the clinical management of these patients. The relationship between the presence of Y chromosome fragments and a higher risk of gonadoblastoma ...