Gynecological Endocrinology back issues from June 2005:
Determination of the fertile window: Reproductive competence of women - European cycle databases
Jun 01, 2005; ... Abstract Objectives. The objective of the present paper is to review the main results of recent European cycle databases on ovulation detection and determination of the fertile window performed by the women themselves. Methods. The ongoing German Long-term Cycle Database ...
Rapid re-enlargement of a macroprolactinoma after initial shrinkage in a young woman treated with bromocriptine
Jun 01, 2005; ... Abstract We report the case of a macroprolactinoma in a 32-year-old woman, who presented with secondary amenorrhea, galactorrhea, increased plasma prolactin level (3259 ng/ml), headache and bi-temporal visual field defect. Magnetic resonance imaging showed a large pituitary tumor. The ...
Pituitary adenylate cyclase-activating peptide/vasoactive intestinal peptide receptors in human normal mammary gland and breast cancer tissue
Jun 01, 2005; ... Abstract Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP) bind similarly to VPAC^sub 1^ and VPAC^sub 2^ receptors, whereas PACAP binds with higher affinity than VIP to PAC^sub 1^ receptors. Here we demonstrate by different approaches the ...
Intrauterine levonorgestrel delivered by a frameless system, combined with systemic estrogen: Acceptability and endometrial safety after 3 years of use in peri- and postmenopausal women
Jun 01, 2005; ... Abstract Objective. To evaluate the acceptability and endometrial safety of a novel intrauterine drug delivery system, FibroPlant-levonorgestrel (LNG), combined with estrogen therapy (ET) in 150 peri- and postmenopausal women, followed-up for at least 3 years. Design. This was a ...
What about breast cancer and cardiovascular disease risks with the best treatments during the climacterium and beyond
Jun 01, 2005; ... There is a general tendency to consider that sex steroid hormones are the only instruments with which to treat women when they enter the climacteric phase of their lives. Both women and physicians share this assumption. Otherwise the ongoing discussions that have exploded all over the world ...
Effect of tamoxifen and raloxifene on cholesterol transformation to bile acids in ovariectomized rats
Jun 01, 2005; ... Abstract Tamoxifen is used as adjuvant therapy for prevention and treatment of metastatic breast cancer, whereas raloxoifene is approved for osteoporosis and is being investigated for breast cancer prevention. The most important aspects of these therapies are focused on their influence ...
Do basal inhibin A and inhibin B levels have value in the diagnosis of polycystic ovary syndrome?
Jun 01, 2005; ... Abstract In the present study we aimed to investigate whether basal inhibin A and B levels in women with polycystic ovary syndrome (PCOS) would be used in diagnosis of the condition. Forty women with PCOS and 40 women with normal cycles (control group) were evaluated. There was no ...
Yolk sac tumor in a young girl: A case report
Jun 01, 2005; ... Abstract Background. Yolk sac tumor is a rare neoplasm characterized by high malignancy given its premature metastasis, that is frequent in adolescence. Case report. A 21-year-old woman came to our observation for an ovarian cyst (13 cm in diameter). Following ...
Breast cancer and sex steroids: Critical review of epidemiological, experimental and clinical investigations on etiopathogenesis, chemoprevention and endocrine treatment of breast cancer
Jun 01, 2005; ... Abstract There is strong epidemiological, experimental and clinical evidence that the etiology of breast cancer is closely related to long-term exposure of breast epithelium to sex steroid hormones. Estrogens can enhance the development of breast cancer by stimulating cell proliferation ...