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Health & Medicine Week articles from September 2003

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<a href="http://www.highbeam.com/Health+~A~+Medicine+Week/publications.aspx?date=200309" title="Articles and back issues from Health & Medicine Week">Health & Medicine Week articles</a>

Health & Medicine Week back issues from September 2003:

Relationship-based intervention improves maternal sensitivity in young mothers.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Relationship-based intervention improves maternal sensitivity in young mothers. According to recent research from Germany, "Adolescent mothers and their infants are a high-risk group. They are exposed to multiple stress and experience ...

Carnegie Mellon develops new process for growing bone.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Carnegie Mellon University's Jeffrey Hollinger and his research team will receive $1.12 million over the next 4 years from the U.S. National Institutes of Health (NIH) to develop a new therapy for regenerating bone. Bone, often called ...

Brain scans, blood tests show positive effects of meditation.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- People who underwent 8 weeks of meditation training produced more antibodies to a flu vaccine and showed signs of increased activity in areas of the brain related to positive emotion than individuals who did not meditate, according to a new study. ...

Women benefit from physical activity during and after menopause.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Women typically reach menopause in their early 50s. Fluctuations in hormonal levels and cycles can make this a time of profound emotional and physical changes for many women. It's also a time when a program of regular exercise can be especially ...

Physical activity definitions broadened to include daily activities.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Even moderate types of exercise provide health benefits. For that reason, a state-based survey, conducted by the U.S. Centers for Disease Control and Prevention (CDC) for the first time includes a broader definition of physical activity. ...

Prevalence of HIV infection increasing in older Americans.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- The prevalence of HIV infection is increasing among older Americans. According to a study from the United States, "In the past 11 years, the cumulative number of AIDS cases reported to the Centers for Disease Control and Prevention in ...

Hypnosis doesn't improve pain relief strategies.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Techniques like relaxation and visualizing a pleasant scene can take the sting out of mild pain, but adding hypnosis to the mix does not make such techniques more effective, according to a new report. Leonard S. Milling, PhD, of the ...

Targeting TNF pathway along with ATRA may represent route to treat leukemias.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Targeting TNF pathway along with ATRA may represent route to treat leukemias. According to a study from Canada, "The nuclear receptor ligand all-trans retinoic acid (ATRA) causes dramatic terminal differentiation of acute promyelocytic ...

Biomaterials company receives U.S. patent on polymer technology.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Life Medical Sciences, Inc., (CHAI) announced that it has been issued a patent covering novel resorbable polymeric materials exhibiting reverse thermal gelation properties that may be used in a variety of biomedical product applications, including ...

Polysaccharide extracts from different algae produce different immune effects.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Polysaccharide extracts from different microalgae produce differing immune effects, but both act as anti-inflammatory agents. According to published research from Spain, "Crude polysaccharide extracts were obtained from aqueous extracts ...

Mast cell product-antagonizing is short-term treatment, long-term solutions needed.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Allergic rhinitis treatment has been short term, based on mast cell product reduction; soon longterm therapy may be possible. "Mast cells not only function as effector cells, but also influence nearly every other cell involved in causing ...

Rhinitis immunotherapy using specific subcutaneous allergen is better than drugs.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Allergic rhinitis may be treated and reduced by subcutaneous allergen specific immunotherapy, instead of drugs. According to recent research from Denmark, "Allergen-specific immunotherapy in the treatment of allergic rhinitis has a ...

Latex allergy may create cross-reactive fruit allergies; kiwi is highest risk.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Patients with allergy to latex should be warned of possible crossreactivity with some fruits; kiwi, banana, avocado being the greatest risk. "Since the first case reported in 1927, latex allergy has attracted the attention of allergists, ...

Protein digestibility related to allergenicity.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Protein digestibility is related to allergenicity, according to a report in a recent issue of Environmental Health Perspectives. "In January 2001 a Joint Food and Agriculture Organization of the United Nations/World Health Organization ...

As U.S. population ages, AD prevalence expected to increase substantially.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- The number of people with Alzheimer disease (AD) in the United States will continue to increase unless new discoveries are made to prevent this illness, according to a new report. Because AD places a heavy burden on the health care ...

Regulation of glucose by HIF-1 protects neurons from amyloid beta peptide.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid beta peptide. According to recent research from the United States, "It is frequently argued that both amyloid beta (A-beta) and oxidative stress ...

Catalytic antioxidant, AEOL 10150, selected for development as ALS treatment.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Incara Pharmaceuticals Corp. (INCR) announced the selection of its catalytic antioxidant, AEOL 10150, for late-stage preclinical development to support an investigational new drug (IND) application for the treatment of amyotrophic lateral sclerosis ...

Rights acquired to ALS gene therapy from Salk Institute.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Ceregene, Inc., announced that it has signed an option agreement with the Salk Institute for Biological Studies for exclusive worldwide rights to its amyotrophic lateral sclerosis (ALS) gene therapy technology. This technology was ...

Progress reported on Cellegesic phase III trial.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Cellegy Pharmaceuticals, Inc., (CLGY) announced that it has made considerable progress with a new 150-patient phase III clinical trial with Cellegesic (nitroglycerin ointment) for the treatment of pain associated with chronic anal fissures. ...

Seniority of surgeon did not affect aneurysm surgery outcome.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- The seniority of the surgeon performing aneurysm repair, among registrars, senior registrars, and consultants, did not affect the outcome of the operation. "Specialist surgical registrars perform surgery as a requirement of their ...

Research hampered by shortage of monkeys.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- A nationwide shortage of rhesus macaque monkeys is hampering efforts to create cures from new information such as the human genome sequence, organ transplant techniques, and the use of stem cells to replace diseased of damaged tissue, scientists ...

Genes showing differential expression in anorexia mutant mouse identified.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Genes showing differential expression in the anorexia mutant mouse model have been identified. According to published research from South Korea, "Differential display (DID) PCR was applied to identify genes regulated by anorexia (anx) ...

Novel 1,3,4-trisubstituted pyrazole derivatives stifle tumor growth mechanisms.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Novel 1,3,4-trisubstituted pyrazole derivatives stifle tumor growth mechanisms. According to recent research published in the journal Chemical & Pharmaceutical Bulletin, "several 1,3,4-trisubstituted pyrazole derivatives were ...

Resistance may occur in bacteria if innate antibiotic proteins are used.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- There may be a risk involved in use of innate antibiotic molecules against bacterial infection. According to a study from Canada, "A remarkable range of novel antibiotics is attracting increasing interest as a major new weapon in the ...

Newly discovered inhibitors of bacterial lactamases may prevent resistance.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- The most important antibiotics in general use today are the b-lactam family of products, but the medical community faces a serious problem with these antibiotics: the increasing development of drug resistance. The resistance is caused by ...

World Health Organization: Farmers should cut antibiotic use.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Farmers worldwide should take a lesson from Danish bacon producers and reduce the use of antibiotics on their livestock to help stem the growth of drug-resistant bacteria in humans, the U.N. health agency says. The World Health ...

N- and C-terminal modifications of negamycin affect antibacterial activity.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- N- and C-terminal modifications of negamycin affected the drug's antibacterial activity. "Negamycin 1 is a bactericidal antibiotic with activity against Gram-negative bacteria, and served as a template in an antibiotic discovery ...

Swiss pharmaceutical group announces European drug submission for palonosetron.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Helsinn Healthcare, SA, a privately owned Swiss pharmaceutical group, announced the submission of their European drug application for palonosetron through the centralized procedure that will lead to the drug approval in all European Union ...

Gallerimycin, a moth-derived antifungal peptide, isn't active against yeast.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- A new antifungal discovered in wax moth, gallerimycin, is not active against yeast. According to published research from Germany, "A novel defensin-like peptide was identified in the greater wax moth, Galleria mellonella. It was ...

TSLC1 gene in human lung cancer is probably a cell adhesion molecule.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- The mouse ortholog of TSLC1, a tumor suppressor gene in human lung cancer, is found to be a cell adhesion molecule that may be expressed more to slow metastasis. According to recent research from Japan, "RA175, a new immunoglobulin ...

Vancomycin-resistant infections are low among liver transplant candidates.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Vancomycin-resistant infections are low among liver transplant candidates. "The orthotopic liver transplant (OLT) population has been particularly affected by the increase in vancomycin-resistant enterococcus (VRE) infections in recent ...

Egr-1 inhibition reverses the transformation of prostate cancer cells.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Egr-1 inhibition reverses the transformation of prostate cancer cells. According to recent research published in the journal Oncogene, "transcription factor early growth response-1 (Egr-1) is a crucial regulator of cell growth, ...

New MAST technology has universal applications for tracking desired mRNA sites.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- New MAST technology has universal applications for tracking desired mRNA sites. "A solution-based method, mRNA accessible site tagging (MAST), has been developed to map the accessible sites of any given mRNA in high throughput fashion ....

Novel DSTP derivative inhibits growth of HIV and herpesviruses.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- A novel DSTP derivative strongly inhibits the cellular activity of HIV and a variety of herpesviruses. According to a study from Germany, "N,N'-bisheteryl derivatives of dispirotripiperazine (DSTP) are a novel class of antiviral ...

Several factors contribute to treatment failure in chronic hepatitis C.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Several factors contribute to treatment failure in chronic hepatitis C. "The treatment of chronic hepatitis C is currently based on a combination of pegylated interferon (IFN)-alpha and ribavirin. When successful, this treatment leads to ...

Researchers close in on scientific definition of arousal.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- For scientists in the field of neurobiology, defining the factors that influence the arousal of brain and behavior is a holy grail. Research published by Rockefeller University scientists in the August 11, 2003, issue of Proceedings of ...

Ventracor reports on first patient.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Medical investigators have provided a progress report on the pilot trial of Ventracor's artificial heart being conducted at the Alfred Hospital in Melbourne. Chief medical investigators Professor Don Esmore and Professor David Kaye said ...

Airway epithelium is in constant repair; allergens create cyclic Th2 response.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Asthmatic airway epithelium is in constant repair mode, and a cycle of Th2 responses due to contact with environmental allergens. "Epithelial cells in the airway wall actively interact with environmental antigens/allergens, both in ...

Biomedical engineer receives $1.8 million grant to study lung damage.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- University of California Irvine biomedical engineer Steven C. George, who is one of the first U.S. scientists to create three-dimensional living lung tissue, has received a $1.8 million grant from the U.S. National Institutes of Health to examine ...

Disodium chromoglycate doesn't help kids with asthma.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- After 35 years of use, advice has changed and doctors are no longer recommended to prescribe disodium cromogycate (DSCG) to children with asthma. New research, just published in The Cochrane Library, defends this change of heart. It ...

Food allergy may be a source to consider for asthma of unknown origin.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Although rare, foods may be a source to investigate in asthma of unknown origin; blinded food challenges can prove it. According to a study from the United States, "Food allergy may present with a variety of respiratory tract symptoms ...

Labeling changes required for drug products that contain salmeterol.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) is announcing the addition of new safety information and warnings to the labeling for drug products that contain salmeterol, a long-acting bronchodilator used to treat asthma and chronic obstructive ...

Patent awarded for therapeutic uses of interleukin-9 receptor protein.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Genaera Corp. (GENR) announced issuance by the United States Patent and Trademark Office of patent number 6,602,850 covering the use of certain soluble human interleukin-9 (IL-9) receptor protein variants as a method for treating bronchial ...

Revotar reports positive results with small molecule selectin antagonist.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Encysive Pharmaceuticals (ENCY) announced its majority-owned German affiliate, Revotar Biopharmaceuticals, AG, reported positive results with bimosiamose in a 12-patient, double-blind, cross-over, allergen challenge study in mild asthmatics. ...

Study links preschool snoring, asthma, and nighttime cough.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Preschool-age children who regularly snore have a higher prevalence of asthma and nighttime cough than children who do not snore, says a new study. The study found that preschool children who snored were twice as likely as nonsnorers to ...

Study of glucocorticoid-receptor interactions may lead to new anti-asthma agents.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Studies on the binding of glucocorticoids to the receptor and subsequent activity may lead to new and better anti-asthma agents. "Glucocorticoids are widely used to treat inflammatory and immune diseases. The most common use of ...

Nramp gene determines efficacy of mycobacteria-based asthma treatment.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- The human Nramp gene determines the efficacy of mycobacteria-based asthma treatment. "Genes controlling antibacterial resistance may be important in the hygiene hypothesis, which states that lack of bacterial infections during childhood ...

Patient enrollment completed in phase IIb CART-2 study with AGI-1067.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- AtheroGenics, Inc., (AGIX) has recently completed enrollment in a phase IIb clinical trial evaluating its proprietary v-protectant drug candidate, AGI-1067, as a treatment for atherosclerosis and post-angioplasty restenosis. This ...

Vitamins restore blood vessel performance in kids with high cholesterol.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Moderate doses of vitamins C and E can slow progression of atherosclerosis in children with a genetic predisposition to high cholesterol, according to new research. This is the first randomized trial to show that moderate doses of the ...

FDA approves skin emulsion.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Sinclair Pharmaceuticals Ltd. has received U.S. Food and Drug Administration registration (510k) for Atopiclair as the first prescription emulsion designed to relieve the symptoms of atopic dermatitis, irritant contact dermatitis, and radiation ...

First patient dosed in phase III atrial arrhythmia studies.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Cardiome Pharma Corp. announced that it has commenced patient dosing in its initial phase III efficacy study of RSD1235 for the acute treatment of atrial fibrillation. The initial study, called ACT 1 (Atrial fibrillation Conversion ...

Array analysis of autoimmune disease leads to vaccine development.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Researchers have developed protein arrays that could be used to diagnose autoimmune diseases, such as multiple sclerosis, earlier than is currently possible. The approach, described in the September 2003 issue of Nature Biotechnology, ...

Autoreactive B lymphocytes may be removable by recombinant fusion proteins.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Autoantigen Fcgamma1 fusion proteins appear to selectively eliminate autoreactive B lymphocytes. According to a study from Germany, "Antigen-specific B cells are key players in many autoimmune diseases through the production of ...

Some MG seronegative patients may be MuSK antibody positive.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- MG seronegative patients may be atypical and some can be identified by MuSK antibody positivity. "Serum antibodies to muscle specific receptor tyrosine kinase (MuSK) were detected in 12/32 patients with generalized seronegative MG. All ...

Systemic lupus erythematosus is more prevalent than was previously thought.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Lupus is more prevalent than previously thought, but many testing positive for the disease have milder cases. "Systemic lupus erythematosus (SLE) is the most diverse of the autoimmune diseases because it may affect any organ of the body ...

Targeted DNA vaccine may reverse disease.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Stanford University Medical Center researchers have developed a way to tailor therapies to combat the specific inappropriate responses of autoimmune diseases in mice. The researchers also have shown that their technique can provide information ...

Efficient Vav3 translocation to B cell membrane rafts requires Grb2 and BLNK.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Vav3 requires Grb2 and BLNK to translocate efficiently to membrane rafts. According to published research from Japan, "Despite the importance of the Vav family proteins for B cell receptor (BCR) signaling, their activation mechanisms ...

Can effective stress management prevent back injuries in nurses?

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- A University of Florida nursing researcher is examining whether stress and pain management techniques can prevent work-related injuries and improve the overall health of nursing professionals, potentially avoiding a worsening of the nation's ...

Proteinases secreted by Bacillus intermedius during sporulation studied.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Proteinases secreted by Bacillus intermedius in the late stages of sporulation have been investigated. According to published research from Russia, "In the late stages of sporulation, cells of Bacillus intermedius 3-19 secreted into the ...

FDA approves Photofrin for the ablation of high-grade dysplasia.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Axcan Pharma, Inc., announced that it has received approval from the U.S Food and Drug Administration (FDA) for the use of Photofrin photodynamic therapy (PDT) in the ablation of high-grade dysplasia (HGD) in Barrett esophagus patients who do not ...

Breast cancer, metastasis, growth reduced with i.v. bee venom therapy in murine model.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- In a mouse breast cancer model, intravenous but not intradermal bee venom reduced metastasis to lung. According to published research from Croatia, "The possible tumor growth-inhibiting and metastasis-inhibiting effects of bee venom in ...

Drug may eliminate transfusions in patients with blood disorder.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- The use of hydroxyurea may eliminate the need for future blood transfusions in children with beta-thalassemia major, an inherited blood disorder, according to a new study. Beta-thalassemia occurs when a person is unable to produce ...

Symptoms, cirrhosis disease progression are known; cause and cure remain elusive.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Some of the symptoms and disease progression are known for primary biliary cirrhosis, but the cause and cure, other than liver transplant, remain elusive. According to published research from the United States, "Primary biliary cirrhosis ...

Percutaneous transhepatic retrieval of a displaced biliary stent is feasible.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- Percutaneous transhepatic retrieval of a displaced biliary stent is feasible. According to a study from Germany, "Biliary stents play an important role in the treatment of jaundice due to malignant and/or benign diseases of the bile ...

A novel skin model invites new ways to explore angiogenesis in vitro.

Sep 01, 2003 ... 2003 SEP 1 - (NewsRx.com & NewsRx.net) -- A novel skin model invites new ways to explore angiogenesis in vitro. "We have previously shown that reconstructed human skin engineered from autologous keratinocytes, fibroblasts, and sterilized donor allodermis stimulates angiogenesis ...