Health & Medicine Week back issues from January 2004:
Health behavioral change models helpful in preventing weight gain.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Health behavioral change models show promise for helping patients avoid unwanted weight gain. According to recent research published in the journal Obesity Research, "Effective procedures are needed to prevent the substantial increases ...
Weight training in older people fights the muscle loss condition.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Older people can reduce their frailty, become more mobile and stave off the muscle-wasting condition known as sarcopenia by working out as little as twice a week, according to the recent report, "Growing Older, Staying Strong: Preventing Sarcopenia ...
Scientists investigate childhood nutrition mystery's causes, effects.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Scientists funded by the U.S. Agricultural Research Service are investigating how nutrition may affect children who develop normally in most ways but grow slowly in the first 3 years of life. Pediatricians describe this condition as "failure to ...
Persons 80 and older make up the largest growing surgical population in U.S.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Surgeons should embrace research, training, and educational opportunities regarding the treatment of elderly patients, researchers say. According to published research from the United States, "Elderly (80+ year old) individuals are the ...
Physicians make house calls to New York City's elderly.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Run by the Wright Medical Center on Aging at New York-Presbyterian Hospital/Weill Cornell Medical Center in New York City, House Calls is a program that brings physicians to the homes of elderly patients and provides care for those unable to visit ...
Risk of prostate cancer is associated with family history of disease.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Risk of prostate cancer is associated with family history of disease, study finds. According to a study from the United States, "An increased risk of prostate cancer associated with a family history of prostate cancer has been documented ...
Female ob-gyns name leading health problems for women; obesity heads list.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Female obstetrician-gynecologists cite obesity as the leading health problem confronting women today, according to a new Gallup Organization survey conducted for The American College of Obstetricians and Gynecologists (ACOG). When women ...
Nearly 6000 AIDS deaths in Malaysia since 1985.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Malaysia has recorded 5934 AIDS deaths since the disease was first reported there 18 years ago, a health official says. The deaths were from a total of 56,667 HIV infections and 8027 AIDS cases reported between 1985 and September this ...
Company issues statement on antiretroviral treatment study.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- GlaxoSmithKline issued the following statement: We welcome the publication in the December 11 [2003] issue of New England Journal of Medicine of the results of ACTG384, a study comparing anti-HIV treatment regimens, conducted by the ...
Lawyer to appeal court ruling on late-term procedure.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- More challenges are in store for an Ohio law that bans a late-term abortion procedure called "partial-birth" abortion by opponents. Cincinnati attorney Alphonse Gerhardstein said the December 17, 2003, 2-1 ruling by the 6th U.S. Circuit ...
Medco receives perfect score, full accreditation from JCAHO.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- In its first application for accreditation, Medco Health Solutions, Inc., (MHS), a pharmacy benefits manager, received a perfect score from the Joint Commission on Accreditation of Healthcare Organizations (JCAHO). Medco Health's perfect ...
Genasense plus chemo demonstrates enhanced activity for older AML patients.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Genta, Inc., (GNTA) announced the presentation of results from several clinical studies that showed safety and potentially enhanced activity when chemotherapy was combined with Genasense (oblimersen sodium) as initial therapy for patients over the ...
Basis of methamphetamine-induced neuronal apoptosis reviewed.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Researchers review the cellular and molecular bases of methamphetamine-induced nerve terminal degeneration and neuronal apoptosis in a recent issue of the FASEB Journal. "Methamphetamine (METH) is a drug of abuse that has long been ...
Life priorities of HIV-seropositive injection drug users revealed.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Findings from a community-based sample reveal the life priorities of HIV-seropositive injection drug users. According to recent research published in the journal AIDS and Behavior, "Using cross-sectional data from an ethnically diverse ...
Teenage pregnancy may put girls at risk for osteoporosis.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- A study by researchers with the Center for Human Nutrition at the Johns Hopkins Bloomberg School of Public Health shows that many teenage mothers had a bone mass that meets the definitions of osteoporosis or osteopenia (the precursor condition to ...
Phase IIa data reported from clinical study of Immunokine in AMN.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Nutra Pharma Corp. (NPHC) announced the publication of a clinical trial of Immunokine in the orphan disease Adrenomyeloneuropathy (AMN). Immunokine was assessed in a placebo-controlled, double-blind study in the U.K. and was administered ...
Guinea pig assays not effective for drug hypersensitivity testing.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Standard guinea pig assays have limited usefulness in the determination of systemic drug hypersensitivity. "The most commonly used assays designed to detect either skin or systemic immune-based hypersensitivity reactions are those using ...
Age-related disease susceptibility may depend on complement regulatory proteins.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Healthy babies, children, and adults have different levels of complement regulatory proteins that may play a role in age-related disease susceptibility and morbidity. According to recent research from Brazil, "previous studies of human ...
Preferred specialty distributor chosen for AMD treatment.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Priority Healthcare Corporation (PHCC) has signed an agreement with Novartis Pharmaceuticals Corporation (NVS) to be a preferred specialty distributor and the preferred specialty pharmacy provider of Visudyne (verteporfin). Visudyne is ...
Ethanol lowers serotonin synthesis; may cause some related psychiatric disorders.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Ethanol lowers enzyme function, serotonin synthesis; may be reason for related psychiatric disorders. "Serotonin (5-hydroxytryptamine, 5-HT) has been implicated in the pathophysiology of many neuropsychiatric disorders, and alcohol is ...
Alcoholics with antisocial personality have blunted emotional reactivity.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Emotional reactivity refers to how people respond to both pleasant and unpleasant events, including ones that cause physical and mental stress. A study has found abnormally low emotional responsiveness among adult male alcoholics with antisocial ...
Frat guys drink more in college, cut back afterward.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- On average, fraternity members drink more than others during their college years, a new study by faculty members at the Universities of Missouri and North Carolina at Chapel Hill confirms, but they rapidly reduce their alcohol intake when their ...
Research findings suggest compound might help in fight against alcoholism.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Relapses remain among the toughest hurdles alcoholics face while trying to avoid the drinking that often ruins their lives and indelibly scars their families. The urge to drink excessively, which most people don't feel at all, is enormously ...
Significant reduction in heavy drinking seen in phase III trial Of Vivitrex.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Alkermes, Inc., (ALKS) announced preliminary results from its phase III study of Vivitrex (naltrexone for injectable suspension) in a total of 624 male and female patients with alcohol dependence. Patients received psychosocial therapy ...
Some IgE epitopes to cedar allergens map to a conserved pectate lyase site.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Some IgE epitopes to mountain cedar pollen allergen Jun a 1 are in a conserved pectate lyase (PL) catalytic site. "Resolution of the 3D structures and IgE epitopes of allergens may identify common or conserved features of allergens. Jun ...
Experimental allergic rhinitis treatment achieves positive safety data.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Rigel Pharmaceuticals, Inc., (RIGL) announced positive clinical safety data for R112, an experimental drug to treat allergic rhinitis, indicating that R112 is well tolerated and demonstrates a favorable safety profile in the study population. ...
Repeat rhinitis therapy with omalizumab is safe for a second ragweed season.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Repeat rhinitis therapy with omalizumab is safe for a second ragweed pollen season. "Two randomized, placebo-controlled, double-blind studies have shown clinical benefit with omalizumab (Xolair), a recombinant humanized monoclonal ...
Asthma mediator LTE4 is still excreted in urine of steroid-treated asthmatics.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Asthma mediator leukotriene E4 continues to be excreted in urine of asthma patients treated with glucocorticoids. "Urinary LTE4 reflects the whole body production of the cysteinyl-leukotrienes (LTC4, LTD4, and LTE4) that are established ...
Food allergies may be treatable with immunotherapy, anti-IgE antibodies, herbs.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Treatments that may work against food allergy include immunotherapy, anti- immunoglobulin E (IgE) antibody therapy, and Chinese herbs. "Up to 5% of young children and 2% of adults suffer from food allergy. Among them, many have ...
Inhaled endotoxin increases lung surfactant protein A, lowers it in lavage fluid.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Surfactant protein A (SP-A) is expressed more in lung, but presence lowered in lung lavage fluid, following repeat exposure to inhaled endotoxin. "Chronically inhaled endotoxin, which is ubiquitous in many occupational and domestic ...
Researchers find connection between poinsettia and latex allergies.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- People with a rubber latex allergy may also be allergic to the popular holiday ornamental poinsettia plant, according to researchers at the Medical College of Georgia. While latex allergies are rare, affecting only about 8% of the ...
Identity and function of gamma-secretase reported.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Researchers report the identity and function of gamma-secretase in a recent issue of the Journal of Neuroscience Research. According to a study from the United States, "Gamma-secretase catalyzes intramembrane proteolysis of various type ...
More positive results reported for Alzhemed.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- At its annual general and special meeting of shareholders, Neurochem, Inc., (NRMX) announced additional positive interim results on cognitive function as measured by the ADAS-cog test in mild-to-moderate Alzheimer Disease (AD) patients ...
Novel murine AD model reveals link between atherosclerosis and beta-amyloidosis.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- A novel murine AD model has confirmed a suspected link between atherosclerosis and beta-amyloidosis. "High-fat/high-cholesterol diets exacerbate beta-amyloidosis in mouse models of Alzheimer disease (AD)," pathologists in the United ...
Presenilin mutation in AD may produce lower activity of dimer in gamma-secretase.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- The gamma-secretase enzyme may contain a presenilin (PS) dimer; PS mutations in Alzheimer disease (AD) may produce lower enzyme activity. According to recent research from the United States, "Notch receptors and the amyloid precursor ...
Relation between cholesterol trafficking and amyloid beta explored.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- The relation between cholesterol trafficking and amyloid beta peptides was explored in a recent issue of the journal Pharmacopsychiatry. "Currently, there is much interest in the association between cholesterol and Alzheimer's disease ....
Researchers isolate Alzheimer-fighting gene.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Researchers have discovered that a special protein-producing gene can help the brain fight the onset of Alzheimer disease, a member of the team behind the finding says. The gene, called Pin 1, generates protein that can help untangle ...
Stress, amphetamines make neurons with glucocorticoid receptors express Fos.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Stress, amphetamines make prefrontal cortex neurons with glucocorticoid receptors (GRs) express Fos. According to a study from the United States, "exposure to stress or amphetamine potently activates the immediate early gene, c-fos, ...
High ciliary neurotrophic factor in ALS patients unrelated to disease severity.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Serum ciliary neurotrophic factor (CNTF)in amyotrophic lateral sclerosis (ALS) patients is higher, but does not correlate with disease severity. "The role of CNTF in the etiopathogenesis of ALS is still not clear. The aim of this study ...
Doctor says a ripped aorta can result from intense weight training.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Bill Linski was lying down watching television when he felt as if something in his chest was being ripped apart. It was. The largest artery in Linski's body, the aorta, was splitting. It took a major operation to keep him ...
Diagnosis and management of hereditary angioedema reviewed.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- A recent review of the diagnosis and management of hereditary angioedema has been published in Transfusion and Apheresis Science. "Hereditary angioedema (HAE) is an autosomal dominant disease characterized by recurrent episodes of ...
Attenuated adenovirus induces thrombocytopenia in rhesus monkeys.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Intravenous administration of replication-incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance. "A replication-incompetent adenovirus vector was administered to rhesus macaques at 1, ...
Stents with cell-cycle inhibitors show promise for further reducing restenosis.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Drug-eluting stents coated with cell-cycle inhibitors have shown great promise for further reducing restenosis, researchers say. According to a study from the United States, "In the 26 years since Gruntzig introduced a simple balloon ...
U.K. company to work with U.S. Naval Medical Research Center on oral anthrax vaccine.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- U.K.-based biotechnology company Microscience has entered into a cooperative research and development agreement (CRADA) with the Naval Medical Research Center (NMRC). The collaboration will evaluate preclinically what Microscience ...
Human antibodies from immunized donors protect against anthrax.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Human antibodies from immunized donors are protective against anthrax toxin in vivo. "A panel of Fabs that neutralize anthrax toxin in vitro was selected from libraries generated from human donors vaccinated against anthrax. At least two ...
Lymphocytic vasculitis associated with anthrax vaccine.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Lymphocytic vasculitis has been associated with the anthrax vaccine. According to published research from the United States, "Anthrax is caused by the spore-forming bacteria Bacillus anthracis. It occurs naturally, but recently has been ...
Amphotericin B lipid complex used to treat invasive fungal infections.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Amphotericin B lipid complex is useful in the treatment of invasive fungal infections. "Amphotericin B lipid complex (ABLC; Abelcet), Enzon Pharmaceuticals) has become the dominant marketed lipid amphotericin B compound to emerge since ...
Therapy of intestinal protozoa outlined.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- A researcher has outlined the treatment of intestinal protozoa in a recent issue of Trends in Parasitology. According to published research from the United States, "Protozoa that parasitize the human intestine and cause disease include ...
Doxycycline inhibits T cell cytokine reaction to staphylococcal exotoxin.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Doxycycline inhibits T-cell proliferation, cytokine reaction to staphylococcal exotoxins (SE); thus may lower toxic effects. According to a study from the United States, "proinflammatory cytokines mediate the toxic effect of ...
California partnership takes lead on simplifying guidelines.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- The California Medical Association Foundation (CMAF) has announced that a 2-year project to simplify recommendations and help physicians appropriately prescribe antibiotics has reached completion. The CMAF's Alliance Working for ...
V. cholerae's resistance genes can leave host, integrate into new one.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Medication may actually stimulate the spread of antibiotic resistance, according to a new report. Vibrio cholerae's antibiotic resistance genes are located on a mobile genetic element, called SXT, which can readily leave the host and integrate into ...
Daptomyclin effective for treating resistant Gram-positive infections.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Daptomyclin is a novel lipopeptide antibiotic for the treatment of resistant Gram-positive infections. According to recent research from the United States, "The continuing rise of resistance rates among bacteria today has led to the ...
Generic amoxicillin with clavulanate potassium launched.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- IVAX Corp. (IVX) announced that its wholly owned subsidiary, IVAX Pharmaceuticals, Inc., is distributing amoxicillin with clavulanate potassium, supplied and licensed by GlaxoSmithKline (GSK). Amoxicillin with clavulanate potassium is an ...
Penicillium chrysogenum can inhibit some aspergilli with PAF protein.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Penicillium chrysogenum produces an antifungal protein, PAF, that is internalized and works on some aspergilli. "The Penicillium chrysogenum antifungal protein PAF inhibits the growth of various filamentous fungi," investigators in ...
V(D)J recombination is controlled by methylation and demethlation of DNA.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- V(D)J recombination is controlled by methylation and demethlation of DNA. According to a study from the United States, "in the mammalian immune system, V(D)J rearrangement of immunoglobulin (Ig) and T-cell receptor (TCR) genes is ...
Varying antimicrobial activity in follicular fluids may be due to lysosyme.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Human follicular fluids (HFF) have varying antimicrobial activities that may be due to lysosyme. "The aim of this study was to explore the antimicrobial activity of HFF, to test the hypothesis that different strains of the same ...
Gastric epithelial cells produce beta-defensins after H. pylori infection.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Gastric epithelial cells produce beta-defensins following Helicobacter pylori infection. "The beta-defensin peptides are known to be potent antibacterials with a wide spectrum of activity. They, therefore, represent an important aspect ...
Lactoferrin-derived peptides have antimicrobial activity beyond iron depletion.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Lactoferrin-derived peptides have antimicrobial activity beyond simple iron sequestration. "Lactoferrin is a member of the transferrin family of iron-binding proteins. Numerous functions have been reported and continue to be reported for ...
Vectosomes improve the delivery of antisense oligonucleotides.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Vectosomes improve the delivery of antisense oligonucleotides. "VP22, a protein of the herpes simplex virus tegument, can form complexes with fluorescein-labeled oligonucleotides. These particles, termed ''vectosomes,'' are efficiently ...
Adenovirus proteinase is inhibited by NO from NONOates; viral infection lowered.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Adenovirus proteinase is inhibited by NO from NONOates; viral infectivity lowered. "Nitric oxide (NO) is an antiviral effector of the innate immune system, but few of the viral targets of NO have been identified. We now show that NO ...
A new heterocyclic HCV replicon RNA synthesis inhibitor has distinct kinetics.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- A new heterocyclic HCV replicon RNA synthesis inhibitor has distinct kinetics. "Recently, a benzo-1,2,4-thiadiazine was shown to be a potent, specific inhibitor of the hepatitis C virus (HCV) RNA polymerase [J Biol Chem, 2002;277:32327] ....
Abnormal stem-cell adhesion molecule expression may underlie aplastic anemia.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Abnormal adhesion molecule expression by hematopoietic stem cells may underlie AA development. "Appropriate adhesion between bone marrow stem cells and the marrow microenvironment is necessary for hematopoiesis, since signals that ...
Monoclonal antibody-based alternative to small-molecule drugs announced.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- InNexus Biotechnology, Inc., announced the scientific publication and disclosure of a monoclonal-antibody-based delivery system for intracellular targets utilizing SuperAntibody technology (SAT). The publication, based on research ...
Database study yields new insights into arthritis drug.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- Researchers at the Veterans Affairs (VA) Medical Center and Washington University School of Medicine in St. Louis have analyzed a national database of VA patients to investigate the effects of the rheumatoid arthritis drug leflunomide in the first ...
Knee treatment value questioned.
Jan 05, 2004 ... 2004 JAN 5 - (NewsRx.com & NewsRx.net) -- U.S. government-approved treatments for knee arthritis in which the joint is injected with fluid often made from rooster combs offer little if any relief, researchers say. Doctors should think twice about recommending hyaluronic acid ...