Health & Medicine Week back issues from October 2004:
Atomoxetine is novel treatment for attention deficit-hyperactivity disorder.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Atomoxetine is a novel treatment for attention deficit-hyperactivity disorder. "Atomoxetine is the first nonstimulant drug approved by the United States Food and Drug Administration (FDA) for the treatment of attention ...
Medical treatment of diabetic foot infections reviewed.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A researcher reviews the medical treatment of diabetic foot infections in a recent issue of Clinical Infectious Diseases. According to a study from the United States, "Diabetic foot infections frequently cause morbidity, hospitalization, ...
New proton pump inhibitor formulation using IV esomeprazole developed.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Researchers have developed a new proton pump inhibitor formulation using IV esomeprazole. According to a study from the United States, "The intravenous (IV) formulation of esomeprazole, the S-isomer of the proton pump inhibitor (PPI) ...
Homeostatic and hedonic risk factors for overeating investigated.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Scientists investigate whether susceptibility to weight gain is characterized by homeostatic or hedonic risk factors for overconsumption in a recent issue of Physiology and Behavior. According to a study from England, "In any particular ...
Laparoscopic gastric bypass possible after failed open gastroplasty.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Laparoscopic gastric bypass is possible after failed open horizontal stapled gastroplasty. According to recent research from the United States, "The number of people in the population who have undergone an operative procedure for morbid ...
West Nile virus and poliomyelitis reviewed.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A scientist reviews West Nile virus and poliomyelitis in a recent issue of the journal Neurology. According to a study from the United States, "West Nile virus (WNV) has recently been associated with a syndrome of acute flaccid ...
11.5% of Biodyne acquired by technology company.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- QuantumBit Induction Technology Inc. (OTC:QBIT) has acquired 11.5% of Biodyne Inc. Biodyne Inc. is a Houston-based, privately held, biomedical development firm, and has engaged Biodyne in the development and implementation of its ...
DataLex ADHD Indicator Report assessment tool introduced.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- The DataLex ADHD Indicator Report from Lexicor, the first biological assessment tool for ADHD, was introduced in Denver, Colorado. The DataLex ADHD Indicator Report uses brainwave data collected from a non-invasive, quantitative ...
FDA approves Methylin Chewable Tablets, Methylin Oral Solution for ADHD.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Alliant Pharmaceuticals, Inc., announced U.S. Food and Drug Administration (FDA) approval of Methylin Chewable Tablets and Methylin Oral Solution for the treatment of ADHD. The two products are the first, and only, chewable tablet and ...
AIDS progression linked to Fok-I polymorphism of VDR gene.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- An association exists between AIDS disease progression rates and the Fok-I polymorphism of the VDR gene in a cohort of HIV-1 seropositive patients. "In addition to its role in mineral metabolism, 1,25-dihydroxivitainin D[subscript]3 ...
Memory CD4+ T cell responses in HIV not restored by antiretroviral therapy.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Central memory CD4+ T cell responses in chronic HIV infection are not restored by antiretroviral therapy. "A strong CD4+ T cell response has been correlated with better control of HIV infection. However, the effect of HIV on the ...
Gag CTL-positive vaccinees recipients do not have anti-gag p17 response.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Gag CTL-positive, HIV-uninfected vaccine recipients expressing the HLA-A*0201 allele did not exhibit immunodominant anti-gag p17 (SL9) responses. According to recent research published in the Journal of Immunology, "According to a number ...
HIV vaccine combination safe and immunogenic in HIV-negative adults.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- An HIV subtype B and E prime-boost vaccine combination was safe and immunogenic in HIV-negative Thai adults. "ALVAC-HIV (vCP1521) and AIDSVAX B/E were evaluated in a phase 1/2 trial of human immunodeficiency virus (HIV)-negative Thai ...
Heat shock protein mediates cross-presentation of exogenous HIV antigen.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Heat shock protein mediates cross-presentation of exogenous HIV antigen on HLA class I and class II. According to a study from the United States, "Strong CD4+ and CD8+ T cell responses are considered important immune components for ...
Immune responses to hemagglutinin/SHIV-like particle vaccine reported.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Scientists report Th cell-independent immune responses to a chimeric hemagglutinin/simian human immunodeficiency virus-like particle vaccine. "CD4+ Th cells are believed to be essential for the induction of humoral and cellular immune ...
Immunization with Listeria controls virus load after FIV challenge.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Oral immunization with recombinant Listeria monocytogenes controls virus load after vaginal challenge with feline immunodeficiency virus. "Recombinant Listeria monocytogenes has many attractive characteristics as a vaccine vector against ...
Methods to monitor oligomeric state of HIV vaccine antigen evaluated.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Researchers have evaluated on-line high-performance size-exclusion chromatography, differential refractometry, and multi-angle laser light scattering analysis for the monitoring of the oligomeric state of human immunodeficiency virus vaccine ...
Papillomavirus-HIV-1 gp41 virus-like particles induce HIV antibodies.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Oral immunization with bovine papillomavirus-HIV-1 gp41 chimeric virus-like particles induced mucosal and systemic neutralizing antibodies against human immunodeficiency virus type 1 (HIV-1). "Human immunodeficiency virus type 1 (HIV-1) ...
Plasmacytoid dendritic cell activation augments SIV-specific T cells.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- CpG-C immunostimulatory oligodeoxyribonucleotide activation of plasmacytoid dendritic cells in rhesus macaques augments the activation of IFN-gamma-secreting simian immunodeficiency virus-specific T cells. "There are two principle ...
Recruiting London gay men into HIV vaccine trial is feasible.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Recruiting London gay men into an HIV vaccine trial is feasible. "This paper describes a study among HIV-negative gay men in London to examine willingness to volunteer for an HIV vaccine trial. HIV-negative gay men (n=506) were surveyed ...
Screening for HIV-specific T-cell responses recommended.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Researchers recommend screening for HIV-specific T-cell responses using overlapping 15-mer peptide pools or optimized epitopes. "The IFN-gamma enzyme-linked immunospot (ELISpot) assay is often used to map HIV-specific CD8 T-cell ...
Chromosomal translocations involving 6p22 breakpoint identified.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Novel chromosomal translocations in acute myeloid leukemia (AML) have been identified and characterized. "The detection of chromosomal aberrations is essential for the diagnosis and therapy" of AML, hematologists in Germany explained. ...
Nicotine patches enhance effects of alcohol.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Transdermal nicotine patches enhance the effects of alcoholic beverages. "Nicotine and alcohol are often consumed together and smokers are more likely than non-smokers to drink alcohol," scientists in the United States noted. "In spite ...
DNA binding to viral enzyme may serve as new target for antiviral drugs.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Scientists at the U.S. Department of Energy's Brookhaven National Laboratory and the Albert Einstein College of Medicine have produced the first molecular-scale images of DNA binding to an adenovirus enzyme - a step they believe is essential for ...
Paper describes new treatment for prevention of postsurgical adhesions.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- ARC Pharmaceuticals, Inc., announced that Dr. Johanne Cashman, director of preclinical research, published a paper entitled "Camptothecin-loaded Films for the Prevention of Postsurgical Adhesions" in the August 2004 issue of Inflammation Research. ...
Prevention programs need to address black female teens' wish to be pregnant.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Health behavior specialists say that programs aimed at preventing pregnancy and sexually transmitted diseases among African American teen girls need to take into account these adolescents' level of desire to become pregnant. Wanting to ...
Study looks at family predictors of girls' sex-typed activities.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Free time activities of children and adolescents are important because they provide a forum for learning new skills and set the stage for identity development, researchers say. To better understand girls' choices of how to spend their ...
Calbindin-D-28K protects renal tubular cells from cyclosporine toxicity.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Calbindin-D-28K protects renal tubular cells from cyclosporine toxicity. According to a study from the United States, "cyclosporine A (CsA) is known to have direct toxicity to renal tubular cells. Its toxicity may be mediated by ...
Sevoflurane exposure is associated with a case of infant hepatitis.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Sevoflurane exposure is associated with a case of infant hepatitis. According to a report from Germany, "an 11-month-old child with primary hyperoxaluria was scheduled for a nephroureteromia procedure. Anesthesia was induced and ...
Social and environmental factors play important role in how people age.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Why do some older people experience a rapid decline in their physical and functional health while some of their peers remain healthy and active? While genes and overall physical health are important, new research shows how psychosocial factors can ...
Monsanto enters collaboration to develop nematode-resistant soybeans.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Monsanto Co. (MOD) and Divergence, Inc., announced a collaborative relationship to develop nematode-resistant soybeans. The targeted pest, soybean cyst nematode, attacks roots of soybean during the growing season, and the annual U.S ....
Neural models are better than statistical models in measuring pig farm odor.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Neural network models perform better than statistical models in measuring pig farm odor because the statistical models are not able to consider the measurement location. "Pork farm odor has become an increasingly important problem for ...
Study says air worse in smoky bars than on truck-choked roads.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- If you're wondering whether a smoky bar or a city street filled with diesel truck fumes is more harmful to your health, you might want to skip your next happy hour. Smoky bars and casinos have up to 50 times more cancer-causing ...
Sweet tooth, behavioral problems tied to alcoholism.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Men who have a sweet tooth and who have trouble controlling their behavior are more prone to alcoholism, and these factors combined were better predictors of the disease than any single individual trait, a recent analysis has found. ...
Youth drinking trends stabilize, consumption remains high.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Although the prevalence of underage drinking has decreased since its peak in the late 1970s, drinking by youth has stabilized over the past decade at disturbingly high levels. The findings, part of a new analysis of youth drinking trends ...
Food Allergy Buddy dining card launched.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Philip Lempert, known by both consumers and the food industry as the "Supermarket Guru" and an expert analyst on consumer, marketing and food safety trends, announced the launch of the Food Allergy Buddy (FAB) Dining Card. FAB is a free ...
Drug in phase 2 clinical trial for patients suffering from peanut allergy.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Tanox, Inc. (TNOX) announced that the first patient has been enrolled in a phase 2 clinical trial evaluating the safety and efficacy of Xolair (omalizumab) in patients suffering from allergy (immediate hypersensitivity) to peanuts. ...
DNA vaccine reverses allergic airway inflammation and eosinophilia.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Reversal of established CD4+ type 2 T helper-mediated allergic airway inflammation and eosinophilia by therapeutic treatment with DNA vaccines limits progression towards chronic inflammation and remodeling. According to published ...
Mom's atopic disease modifies effects of prenatal risk factors on exhaled NO.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- According to a study from Switzerland, maternal atopic disease modifies the effects of prenatal risk factors on exhaled nitric oxide in infants. U. Frey and colleagues, University Hospital of Bern, measured exhaled nitric oxide (eNO) in ...
Side effects greater with aqueous than depot therapy for bee venom allergy.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Early local side effects occur at higher frequency with aqueous than with depot immunotherapy for Hymenoptera venom allergy. "Venom immunotherapy has proven a very effective method for the treatment of allergy to Hymenoptera venom ....
Age-related myelin breakdown may be regionally heterogenous.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Study suggests that differences in myelin properties make later-myelinating regions more susceptible to myelin breakdown. According to published research from the United States, "Human and nonhuman primate data suggest that the ...
Colostrinin found to be potential major advance in Alzheimer disease treatment.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- In vivo study in chicks shows that ReGen's Colostrinin reduces memory impairment induced by the toxic protein involved in Alzheimer disease. An in vivo study showing that pretreatment with Colostrinin (ReGen Therapeutics Plc) can reduce ...
Cyclooxygenase-3 expression is ancillary to COX-mediated neuropathogenesis.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Cyclooxygenase-3 expression is ancillary to COX-mediated neuropathogenesis. According to published research from the United States, "the cyclooxygenase (COX) superfamily of prostaglandin synthase genes encode a constitutively expressed ...
Immunoglobulins might be promising treatment for AD.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Intravenous immunoglobulin might offer a promising treatment for Alzheimer disease, suggests preliminary research. Deposits of amyloid protein, which progressively damage brain tissue, are a cardinal feature of Alzheimer disease. A ...
Mild AD leads to errors on driving test.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- People with mild Alzheimer disease make more mistakes on a driving test than older people with no cognitive problems, according to a new study. The study involved an on-road driving test with 32 people with mild Alzheimer disease and 136 ...
Murine cerebral amyloidosis models exhibit impaired vascular formation.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Murine cerebral amyloidosis models exhibit impaired vascular formation. "Abeta peptides are naturally occurring peptides, which are thought to play a key role in the pathophysiology of Alzheimer disease (AD). In AD cases, levels of ...
S- but not R-enantiomers of flurbiprofen and ibuprofen are neuroprotective.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- S- but not R-enantiomers of flurbiprofen and ibuprofen are neuroprotective. According to recent research from Canada, "The protective effects of non-steroidal anti-inflammatory drugs (NSAIDs) in Alzheimer's disease have been demonstrated ...
Spermidine and spermine levels higher in female ALS patients than males.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Study data suggest that regulation of polyamine levels is maintained in end-stage amyotrophic lateral sclerosis, and, interestingly, show that in female patients, spermidine and spermine levels in the ventral horn region are higher than those of ...
Hazards of surgery and anesthesia for drug, alcohol abusers presented at meeting.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Substance abusers who think it's okay not to tell their oral and maxillofacial surgeon about their drug use are putting themselves at risk for surgical complications, even if they're having a procedure as relatively straightforward as a wisdom ...
Novel airway approach algorithm developed.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A novel airway management algorithm has been developed for anesthesiologists. "Anticipatory decision-making in airway management requires the integration of both history and physical examination findings," physicians in the United States ...
Patients with cardiac RyR defects had general anesthesia without complications.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A recent report describes the use of volatile anesthetics and succinylcholine in patients with cardiac ryanodine receptor defects. According to the report from Finland, "Familial polymorphic (catecholaminergic) ventricular tachycardia is ...
Phosphorylation alters Xenopus Ca-activated Cl currents.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Phosphorylation alters Xenopus Ca-activated Cl currents (I[subscript]Cl(Ca)), a finding that could complicate anesthesia research. I[subscript]Cl(Ca) "are used frequently as reporters in functional studies of anesthetic effects on G ...
Cellular mechanisms that control regulation of TASK-1 by PAF are examined.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Activation of protein kinase C epsilon inhibits the two-pore domain K[superscript]+ channel, TASK-1, inducing repolarization abnormalities in cardiac ventricular myocytes. "Activation of the platelet-activating factor (PAF) receptor ...
Combination may provide a potential treatment of arterial thrombotic disorders.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Cilostazol and dipyridamole synergistically inhibit human platelet aggregation Scientists in the United States report, "It has been previously shown that cilostazol (Pletal(R)), a drug for relief of symptoms of intermittent claudication, ...
Fluid shear stress induces endothelial KLF2 gene expression.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Fluid shear stress induces KLF2 gene expression in endothelial cells. "Fluid shear stress is crucial for maintenance of a properly functioning endothelium," scientists in the United States explained. In a recent study, J.P ....
Glycoproteins have a procoagulant role in collagen-dependent thrombus formation.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A recent report described facilitating roles of murine platelet glycoprotein Ib and (alpha)IIb(beta)3 in phosphatidylserine exposure during vWF-collagen-induced thrombus formation. According to published research from Netherlands, ...
New treatments may soon include agents known as the metabolic modulators.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A recent report discusses metabolic approaches to the management of ischemic heart disease. According to a published report from the United States, "The number of patients with coronary artery disease and its risk factors is increasing ...
Rac1 GTPase is a strategic target for tumor elimination.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Rac1 GTPase is a strategic target for tumor elimination. "Hypoxia-induced angiogenesis plays an important role in the malignancy of solid tumors. A number of recent studies including our own have suggested that Rho family small GTPases ...
Responses to BK of peripheral arteries and coronary arteries correlated.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- The relationship between flow-mediated brachial artery vasodilation and coronary vasomotor responses to bradykinin was compared to those to acetylcholine. According to a study from Japan, "Flow-mediated dilation (FMD) of brachial artery ...
Serial surveillance of patients is vital after arterial switch operation.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Risk factors for neo-aortic root enlargement and aortic regurgitation following arterial switch operation are described in a recent report. According to a study from the United States, "The objectives of this study were to evaluate ...
Slowed VO[subscript]2 kinetics occur only with exercise of the affected limbs.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A recent report describes pulmonary Vo[subscript]2 dynamics during treadmill and arm exercise in peripheral arterial disease. "Slowed pulmonary O[subscript]2 uptake (VO[subscript]2) kinetics in peripheral arterial disease (PAD) have been ...
Vascular and valvular calcium levels linked.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A significant link between vascular and valvular calcium levels has been demonstrated. In a study conducted by cardiologists in the United States, the "epidemiology of and association between vascular and valvular calcium as quantified ...
aPT IgG is a significant marker for deep vein thrombosis/pulmonary embolism.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A high prevalence of anti-prothrombin antibody has been reported in patients with deep vein thrombosis. According to published research from Japan, " ...[Our] study was designed to determine the prevalence of lupus anticoagulant (LA) ...
Gene-targeting experiments have elucidated AT[subscript]1 receptor functions.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- A recent report describes experiments with type I angiotensin (AT[subscript]1) receptor functions through gene targeting According to recent research published in the journal Acta Physiologica Scandinavica, "The renin-angiotensin system ...
Chymase and carboxypeptidase A have key roles in generating and degrading Ang II.
Oct 04, 2004 ... 2004 OCT 4 - (NewsRx.com & NewsRx.net) -- Scientists have reported on the cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin II. "The octapeptide angiotensin II (Ang II) exerts a wide range ...