Heart Disease Weekly back issues from June 2003:
Cognitive decline after bypass surgery mostly temporary and reversible.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- More than two-thirds of patients who undergo coronary artery bypass surgery may experience problems with their ability to think, remember and learn, and are slower at tasks like writing and drawing immediately following surgery than they were ...
Trans-fatty acids in fat tissue associated with risk of heart attack.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- High 18:2 trans-fatty acids in adipose tissue are associated with increased risk of nonfatal acute myocardial infarction in Costa Rican adults. According to a study from the United States and Costa Rica, "Trans-fatty acid intake is ...
Common gene variant increases risk.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- A common version of a gene has been identified as a potent risk factor for early-onset atherosclerosis, report the Johns Hopkins scientists who first linked it to shorter life expectancy in humans. Using information and samples from two ...
Platelets and their P-selectin actively promote advanced lesion development.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Platelets and their P-selectin actively promote advanced atherosclerotic lesion development. "P-selectin is an adhesion molecule expressed on activated platelets and endothelium. It is known to play an important role in atherosclerosis. ...
Coronary sinus hepatocyte growth factor levels correlate with collateralization.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Coronary sinus hepatocyte growth factor levels correlate with collateralization. "The therapeutic use of angiogenic factors to protect ischemic myocardium is limited by our incomplete understanding of their endogenous production. We ...
Cytokine cross-talk hampers revascularization during inflammation or ischemia.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Cytokine cross-talk hampers revascularization during inflammation or ischemia. "Tumor necrosis factor (TNF) alpha is a critical mediator of inflammation; however, TNF-alpha is rarely released alone and the 'cross-talk' between different ...
AV interval dynamics significantly precede change in R-R intervals.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- AV interval dynamics significantly preceded the change in R-R intervals. "Heart rate turbulence (HRT) represents a biphasic chronotropic response of sinus rhythm to a single ventricular premature beat (VPB). "It consists of ...
Catheter intervention effective; KD sequelae are independent risk factors.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Catheter intervention is effective in acute coronary syndrome; Kawasaki disease (KD) sequelae are independent coronary risk factors. "Acute coronary syndrome occurred in 2 young adults who had a history of Kawasaki disease (KD), but few ...
Better outcomes come from i.v. nicorandil along with coronary reperfusion therapy.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Intravenous nicorandil gives better outcomes along with coronary reperfusion therapy for patients with acute myocardial infarction. "The aim of this retrospective study was to assess whether intravenous nicorandil, a hybrid of NO and a ...
Increased serum MMP-1 concentration predicts advanced LV remodeling.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Increased serum MMP-1 concentration predicts advanced LV remodeling in patients with acute myocardial infarction. "The left ventricular ejection fraction (LVEF) is one of the major prognostic factors after acute myocardial infarction ...
Infusion inhibits adenosine-induced cardiac action.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Adenosine infusion inhibits adenosine-induced cardiac actions, but enhances acetylcholine-induced actions. According to a study from Japan, "Using isolated, blood-perfused canine atrial preparations, adenosine was continuously ...
A polypropylene suture ruptured after ascending aorta replacement.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- A polypropylene suture can rupture after ascending aorta replacement. "In surgical procedures, and specifically in cardiovascular operations, the polypropylene monofilament is a widely used suture material," scientists in Switzerland ...
In situ internal mammary artery grafting safe during coronary bypass operations.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- In situ right internal mammary artery grafting can be done safely during routine coronary bypass operations. "Bilateral internal mammary artery grafting is associated with improved long-term patient outcomes. In situ right internal ...
Lipid modification strategy to reduce coronary events must be better implemented.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Lipid modification strategies proven to reduce risk for coronary events must be better implemented. According to recent research published in the Journal of the American College of Cardiology, "Research into the oxidation of ...
TXA[subscript]2 receptor blockade prevents macrophage infiltration.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- TXA[subscript]2 receptor blockade prevents macrophage infiltration after arterial intervention for atherosclerosis. "Macrophage infiltration appears to play an important role in restenosis after arterial intervention. Monocyte ...
Arctic Circler progress announced.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- CryoCath Technologies, Inc., (CYT) announced that on April 25, 2003, at the 69th Annual Meeting of the German Cardiac Society in Mannheim, Germany, two presentations were made documenting the clinical experience of two European cardiovascular ...
Puncture provides stable electrode-endocardial contact for ablation application.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Atrial transseptal puncture provides stable electrode-endocardial contact for ablation energy application. "Atrial transseptal puncture is a technique that provides pervenous access to the left heart," scientists writing in the Journal ...
Reversible electrical remodeling occurs in sinus node and in atrial myocardium.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Reversible electrical remodeling occurs both in sinus node and in atrial myocardium after atrial and ventricular pacing. According to recent research published in the journal Pacing and Clinical Electrophysiology, "It has been shown in ...
Cholesterol researchers win top medical prize.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Two doctors, whose Nobel Prize-winning studies led to the development of cholesterol-lowering drugs, have been awarded the nation's richest prize for medicine and biomedical research. Michael Brown and Joseph Goldstein, both of the ...
Dominant role of the sympathetic system found in stable preterm infants.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Dominant role of the sympathetic system found in stable preterm infants. According to a study from the Netherlands, "To examine the baroreceptor reflex function, a beat-to-beat analysis between systolic blood pressure (SBP) and R-R ...
Heart scanning test does not motivate patients to improve risk factors.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Having an electron beam tomography scan performed to detect evidence of coronary disease is not associated with an improvement in modifiable cardiovascular risk 1 year later, according to a new study. Evidence exists that cardiovascular ...
Modification for technique for cardiac transplantation is presented.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Modification of bicaval anastomosis for an alternative technique for orthotopic cardiac transplantation is presented. "We describe an alternative technique for orthotopic cardiac transplantation (OCT), which we use to combine the ...
Pacing prevents multiple ICD shocks accompanied by improvement in LV function.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Biventricular pacing prevents multiple ICD shocks accompanied by improvement in LV systolic function. "This study presents a patient with idiopathic dilated cardiomyopathy who had suffered from multiple ICD shocks. Amiodarone and ...
Palliative balloon aortic valvuloplasty is performed before craniotomy.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Palliative balloon aortic valvuloplasty can be performed before craniotomy. "Severe aortic stenosis can pose a serious hazard for noncardiac surgery as patients with this condition have a high risk for developing perioperative cardiac ...
Brugada anomalies observed in inferior, right precordial lead.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Brugada anomalies related to unique SCN5A mutation can be observed either in inferior or right precordial leads. According to a study from France, "Mutations in the SCN5A gene can lead to the Brugada syndrome, a genetically inherited ...
Induction of ventricular fibrillation can be predicted by noninvasive methods.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Induction of ventricular fibrillation can be predicted by noninvasive methods in asymptomatic patients with Brugada syndrome. "Ventricular fibrillation (VF) is induced in some asymptomatic patients with Brugada syndrome (BS), but the ...
Technology designed will be applicable at Bachmann bundle, RA appendage.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Capture recognition technology designed will be applicable at Bachmann bundle versus right atrial appendage capture. "The tissue in the high intra-atrial septum in the region of Bachmann's Bundle (BB) exhibits electrophysiological ...
Single ventricle palliation serves as a bridge to heart transplantation.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Single ventricle palliation serves as a bridge to heart transplantation. According to recent research published in the journal Annals of Thoracic Surgery, "A prenatal echocardiogram revealed a large right ventricular mass. Following ...
Channels may be key determinants of cardiac excitability, impulse propagation.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Cardiac Na channels may be useful as key molecular determinants of cardiac excitability and impulse propagation. According to a study from The Netherlands, "Sodium ion (Na) influx through cardiac Na channels triggers the action potential ...
EphrinA1 inactivates vascular smooth muscle cell spreading via Rac/PAK pathway.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- EphrinA1 inactivates vascular smooth muscle cell spreading via Rac/PAK pathway According to recent research published in the Journal of Cell Science, "interactions between the Eph receptor tyrosine kinase and ephrin ligands transiduce ...
Proprietary embolic management system acquired for cardiac surgery.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Edwards Lifesciences Corporation (EW) announced that it has acquired various assets of Embol-X, Inc., a venture-financed medical technology company based in Sacramento, California. Financial terms of the transaction were not disclosed. ...
Antioxidant activities are positive side effect of its antihypertensive activity.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Antioxidant and antielastasic activities of nicardipine are positive side effect of its antihypertensive activity. "Activated neutrophils which produce certain proteases, such as elastase and reactive oxygen species (ROS) are involved in ...
Celiprolol increases coronary blood flow, reduces myocardial ischemia.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Celiprolol increases coronary blood flow and reduces severity of myocardial ischemia via nitric oxide release. According to recent research from Japan, "Celiprolol is a selective beta(1)-adrenoceptor antagonist with antihypertensive ...
Embusartan blocks AT[subscript]1 receptor more effectively than losartan.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Embusartan blocks AT[subscript]1 receptor more effectively than losartan within blood-brain barrier. "After peripheral administration, AT[subscript]1 receptor blockers appear to be able to enter the brain and cause AT[subscript]1 ...
Ouabain has opposite effects on basal, ET-1-induced ERKs phosphorylation.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Ouabain treatment has opposite effects on basal and ET-1-induced ERKs phosphorylation in rat heart and tail artery. According to recent research from Italy, "Endogenous ouabain may play a role in the control of cardiovascular system ...
Positive effect associated with signal pathway linking Na+/K+-ATPase to ERK1/2.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Positive inotropic effect of ouabain is associated with signal pathway linking Na+/K+-ATPase to ERK1/2. According to published research from the United States, "Exposure of cultured rat cardiac myocytes to ouabain is known to cause the ...
Rosuvastatin protects ischemic reperfused myocardium.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Rosuvastatin protects ischemic reperfused myocardium in normocholesterolemic rats. "The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) have been shown to upregulate endothelial nitric oxide synthase in isolated ...
Zealand Pharma enters collaboration for ZP123.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Zealand Pharma, A/S, has entered into a development and license agreement with Wyeth (WYE). Under the terms of the agreement, the two companies will codevelop ZP123, Zealand's novel drug candidate for the treatment of arrhythmias and ...
Microwave, irrigated, pulsed, or conventional RF energy sources compared.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Microwave, irrigated, pulsed, or conventional RF energy sources are compared for catheter ablation. "The aim of the study was to compare the diameter of endomyocardial lesions induced with the delivery of microwave, cooled, or pulsed ...
Ablation with conventional vs irrigated tip catheter has similar outcomes.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Cavotricuspid isthmus ablation with conventional 8-mm tip vs. irrigated tip catheter has similar outcomes. According to a study from France, "To test the theoretical superiority of irrigated tip catheters to achieve complete ...
A Mallory-Weiss tear complicates intraoperative transesophageal echocardiography.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- A Mallory-Weiss tear can complicate intraoperative transesophageal echocardiography. "A Mallory-Weiss tear occurred as a complication of intraoperative transesophageal echocardiography carried out in a 62-year-old man who underwent ...
Argatroban may be used as anticoagulant for patients with heparin allergy.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Argatroban may be used as alternative anticoagulant for patients with heparin allergy during coronary artery bypass surgery. According to recent research from Japan, "Although heparin allergy is a rare but well-documented entity, ...
Cardiac surgeons prove decreased mortality with off-pump surgery.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- New York University Medical Center's cardiac surgeons Eugene Grossi, MD, and Aubrey Galloway, MD, announced new study findings demonstrating significantly lowered mortality, stroke, and overall risk of complications using off-pump coronary artery ...
Pulmonary impairment persists up to 4 months after CABG.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Pulmonary impairment can persist up to 4 months after CABG. According to recent research from Sweden, "The objective of this study was to describe the pulmonary function and pain 4 months after coronary artery bypass graft surgery. ...
Endogenous adenosine activates both A(2A) and A(2B) receptors.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Endogenous adenosine increases coronary flow by activation of both A(2A) and A(2B) receptors. "To clarify which adenosine receptor subtype(s) are responsible for regulation of coronary flow through endogenous adenosine, coronary vascular ...
A new dual chamber implantable cardioverter defibrillator is highly effective.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- A new dual chamber implantable cardioverter defibrillator is highly effective. "Eighty-nine patients with a documented history of atrial tachyarrhythmias or fibrillation (AF) received a cardioverter defibrillator designed to selectively ...
Implantable cardioverter defibrillation is underprovided in the United Kingdom.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Implantable cardioverter defibrillation is underprovided in the United Kingdom. According to a study from England, "To determine the number of patients fulfilling recently issued national guidelines on the use of ICDs in patients with ...
Morphology Discrimination improved the specificity of the Rate Branch algorithm.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Morphology Discrimination improved the specificity of the Rate Branch algorithm. According to published research from Italy, "Morphology Discrimination is a discriminator based on QRS morphology analysis that has been recently ...
Patients with predicted low DFTs may be eligible for abbreviated ICD testing.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Patients with predicted low DFTs may be eligible for abbreviated ICD testing. "The aim of this study was to identify clinical characteristics that distinguish patients with high DFTs and assess the prognostic implication," scientists in ...
Overlake Hospital to offer cardiac patients new Cypher stent.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Washington-based Overlake Hospital now offers the new Cypher Sirolimus-eluting Stent, approved by the U.S. Food and Drug Administration (FDA) for the treatment of blocked coronary arteries. The new Cypher Stent, which is approved for the ...
3D Echocardiography can be used as guide for interatrial septum pacing.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- 3D echocardiography can be used as guide for interatrial septum pacing. "Interatrial septum (IAS) pacing has been proposed for the prevention of paroxysmal atrial fibrillation. "IAS pacing is usually guided by fluoroscopy and ...
Ttricuspid valve endocarditis due to Candida colliculosa is reported.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- A case of native tricuspid valve endocarditis due to Candida colliculosa is reported. According to recent research from Turkey, "Candida colliculosa, which grew in blood cultures of a 71-year-old retired man with fever of unknown origin ...
Magnetic resonance imaging is useful in assessment of condition.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Magnetic resonance imaging is useful in assessment of endomyocardial disease. According to a study from Spain, "Endomyocardial disease is a restrictive cardiomyopathy that includes Loffler endocarditis, which is characterized by ...
Virus-associated pulmonary edema linked to left ventricular failure in children.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- According to a study from Taiwan, "Epidemics of enterovirus 71 infections caused the rapid death of many children in Malaysia in 1997 and in Taiwan in 1998. Pulmonary edema occurred in most of the fatal cases and was considered to be neurogenic ....
Receptors have regulatory effects on cardiac sarcolemmal Na+/H+ exchanger.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- G protein-coupled receptors have regulatory effects on cardiac sarcolemmal Na+/H+ exchanger activity. According to a study from England, "In cardiac myocytes, sarcolemmal Na+/H+ exchanger (NHE) activity is subject to regulation by a ...
Glossopharyngeal neuralgia with cardiac syncope is treated surgically.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Glossopharyngeal neuralgia with cardiac syncope can be treated surgically. "A glossopharyngeal neuralgia case with cardiac asystole is presented. The sinus mode dysfunction and subsequent syncope with pain appears to be the most ...
New target for insulin found in the heart.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Scientists at Bristol University have found evidence for a new protein in the heart that could one day aid development of new drugs to regulate the heart. The ability of the heart to function as a pump that drives blood around the body ...
Exposure to IHA induces different changes in adenylyl cyclase activity.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Exposure to IHA induces different changes in adenylyl cyclase activity in hearts of young and adult Wistar rats. "This study investigates changes of adenylyl cyclase activity in the heart of young and adult Wistar rats exposed to ...
Childhood high blood pressure related to genetics.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- With the number of children developing primary hypertension increasing at a shocking rate, the need to determine the cause is becoming more important. Researchers at Columbus Children's Research Institute (CCRI), located on the campus of Columbus ...
The Angstrom series of defibrillators have decreased longevity.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- The Angstrom series of defibrillators have decreased longevity. According to recent research published in the journal Pacing and Clinical Electrophysiology, "ICDs are used frequently to treat malignant ventricular arrhythmias. ...
Intima may become so thin that stent struts are exposed, may lead to thrombosis.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- After intracoronary radiation, intima becomes so thin that some stent struts are exposed to the lumen, which may be related to occurrence of late thrombosis. "Little is known about the alterations of the vascular surface after radiation ...
Cardiac Na+/H+ exchanger has role.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Cardiac Na+/H+ exchanger has role during ischemia and reperfusion. "The coupled exchanger theory describes one of the central mechanisms of damage in the ischemic heart. The theory proposes that anaerobic glycolysis produces lactate and ...
Cariporide may have no long-term functional or biochemical benefits.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Cariporide may have no long-term functional or biochemical benefits in ischemia/reperfusion model. According to a study from Canada, "Using both [superscript]31P and [superscript]1H cardiac magnetic resonance techniques, it is possible ...
Melatonin may represent novel therapeutic approach for prevention of I/R injury.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Melatonin may represent novel therapeutic approach for prevention of ischemia/reperfusion (I/R) injury. "The pineal hormone melatonin has been reported to protect tissue from oxidative damage. This study was designed to determine ...
Isoflavone supplementation does not affect lipid profiles in women.
Jun 01, 2003 ... 2003 JUN 1 - (NewsRx.com & NewsRx.net) -- Supplementation with purified red clover (Trifolium pratense) isoflavones did not affect the lipid profiles of premenopausal women. "Consumption of isoflavone-rich soybean protein is reported to reduce total and LDL-cholesterol, but the ...