Recently added articles from In Vitro Cellular & Developmental Biology:
- Osmotic stress induces terminal differentiation in cultured normal human epidermal keratinocytes
- May 01, 2008; Mammone, Thomas; Ingrassia, Michael; Goyarts, Earl ... Abstract The signals for epidermal differentiation and barrier formation are largely unknown. One possible signal is dehydration or osmotic stress. To test this hypothesis, we investigated the effects of osmotic stress on markers of differentiation of normal human keratinocytes in culture ....
- The use of a high-throughput luminescent method to assess CYP3A enzyme induction in cultured rat hepatocytes
- May 01, 2008; Garcia, Martha C; Ma, Dongping; DiCioccio, A Thomas; Cali, James ... Abstract Assessment of a new chemical entity for cytochrome P450 (CYP) enzyme induction at an early stage in discovery is crucial to prevent potential drug-drug interactions. CYP3A, the most abundant CYP isoform in the liver, metabolizes approximately 50% of drugs currently on the market and is ...
- Nestin-positive spheres derived from canine bone marrow stromal cells generate cells with early neuronal and glial phenotypic characteristics
- May 01, 2008; Kamishina, Hiroaki; Cheeseman, Jennifer A; Clemmons, Roger M ... Abstract Bone marrow stromal cells (BMSCs) isolated from humans and rodents have been shown to generate neural cells under specific culture conditions and after transplantation in the central nervous system. The apparent plasticity of BMSCs has therefore been a target of intensive research in ...
- Rapid and quantitative detection of p38 kinase pathway in mouse blood monocyte
- May 01, 2008; Zhao, Jingyong; Evans, Glenn; Li, Weiming; Green, Lisa; Chu, Shaoyou; Marder, Phil; Na, Songqing ... Abstract The p38α mitogen-activated protein kinase (MAPK) is essential in controlling the production of many proinflammtory cytokines, and its specific inhibitor can effectively block their production for treating human diseases. To effectively identify highly specific p38α inhibitors ...
- Cytological properties of an Aedes albopictus mosquito cell line infected with Wolbachia strain wAlbB
- May 01, 2008; Fallon, Ann M ... Abstract In vitro production of the obligate intracellular bacterium, Wolhachia pipientis, is essential to its manipulation as a genetic tool to spread transgenes within vector populations. We have adapted the Wolbachia-infected Aa23 Aedes albopictus mosquito cell line to Eagle's minimal medium, ...
- Electrophysiological and immunocytochemical characterization of DRG neurons on an organosilane surface in serum-free medium
- May 01, 2008; Liu, Jie; Rumsey, John W; Das, Mainak; Molnar, Peter; Gregory, Cassie; Riedel, Lisa; Hickman, James J ... Abstract We are attempting to recreate a stretch reflex circuit on a patterned Rio-MEMS (bio-microelcctromeehanical systems) chip with deflecting micro-cantilevers. The first steps to recreate this system is to be able to grow individual components of the circuit (sensory neuron, motoneuron, ...
- Isolation and characterization of mesenchymal stem cells derived from bone marrow of patients with Parkinson's disease
- May 01, 2008; Zhang, Zhiqing; Wang, Xiaofang; Wang, Suping ... Abstract Mesenchymal stem cells (MSCs) are capable of self-renewing and differentiating into multiple tissues; they are expected to become a source of cells for regenerative therapy. Compared to allogeneic MSCs, autologous MSCs from patients needing cell-based therapy may be an ideal alternative ...
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