Recently added articles from Indian Journal of Cancer:
Statement on publishing clinical trials in Indian biomedical journals
Apr 01, 2008; Satyanarayana, K; Sharma, A; Parikh, P; Vijayan, V; Sahu, D; Nayak, B; Gulati, R; Parikh, M; Singh, P; Bavdekar, S; Sreehari, U; Sahni, P ... The registration of clinical trials will help improve reliability of data generated, help clinicians interpret research, minimize duplication of trials and prevent exposure of volunteers to potential risks. [1] The Clinical Trial Registry India (CTRI; www.ctri.in) hosted at the National ...
Hairy cell leukemia: Clinical, pathological and ultrastructural findings in Asian-Indians
Apr 01, 2008; Chatterjee, T; Panigrahi, I; Mahapatra, M; Pati, H; Kumar, R; Naithani, R; Wadhwa, S; Choudhry, V; Saxena, R ... Introduction Hairy cell leukemia (HCL) is an indolent, chronic B-cell lymphoproliferative disorder comprising approximately 2 to 3% of all adult leukemias. [1] It occurs more frequently in men (Ratio 4:1) and mean age at diagnosis is approximately 52 years. It is primarily a disease of ...
Bone marrow morphological changes in patients of chronic myeloid leukemia treated with imatinib mesylate
Apr 01, 2008; Joshi, S; Sunita, P; Deshmukh, C; Gujral, S; Amre, P; Nair, C ... Introduction Chronic myeloid leukemia (CML) is a clonal stem cell disorder associated with the reciprocal translocation between chromosomes 9 and 22 resulting in formation of the bcr-abl chimeric protein with tyrosine (abl) kinase activity. [1] The enhanced tyrosine kinase activity has ...
Mammographic density as a risk factor for breast cancer in a low risk population
Apr 01, 2008; Attam, A; Kaur, N; Saha, S; Bhargava, S ... Introduction Breast cancer is the most common malignancy among women globally. In India, breast cancer, though less common than in western populations, has become the leading cancer in females in metropolitan cities like Delhi, Mumbai, Bangalore, Kolkata and Bhopal overtaking carcinoma ...
Cervical lymph node metastases of squamous cell carcinoma from an unknown primary: Outcomes and patterns of failure
Apr 01, 2008; Mistry, R; Qureshi, S; Talole, S; Deshmukh, S ... Introduction Metastases of squamous cell carcinoma (SCC) to cervical lymph nodes from primary of unknown origin (PUO) represent 1% to 2% of head and neck cancers. [1],[2],[3] The explanations for this unusual form of presentation are of speculative nature: spontaneous regression of the ...
Immunoprofile of Hodgkin's lymphoma in India
Apr 01, 2008; Patkar, N; Mehta, J; Kulkarni, B; Pande, R; Advani, S; Borges, A ... Introduction Hodgkin's lymphoma (HL), first described by Thomas Hodgkin in 1832 is one of the most enigmatic diseases known. In recent years, immunophenotyping has contributed significantly to our understanding the nature and biology of the diagnostic Reed Sternberg (RS) cell. It ...
Wunderlich's syndrome with hepatic angiomyolipoma in tuberous sclerosis
Apr 01, 2008; Mongha, R; Bansal, P; Dutta, A; Das, R; Kundu, A ... Introduction Wunderlich's syndrome is one of the most feared complications of renal angiomyolipoma and should be managed aggressively. Nephron sparing approach is preferable, especially in TS with bilateral and multicentric angiomyolipomas. Hepatic angiomyolipomas, though rare, may be ...
Need for the appraisal of uncommon side effects of a commonly prescribed drug- Imatinib
Apr 01, 2008; Attili, VSS; Anuradha, V; Raju, SHK ... Dear Sir, The concept of targeted therapy is emerging as an innovative, high potential new trend in cancer therapy. These drugs are not supposed to affect the normal cells and act selectively on cancer cells there by minimizing the systemic side-effects. However the results are not as ...
Adult T cell leukemia: A typical case from India
Apr 01, 2008; Jain, P; Gupta, S; Prabhash, K; Patkar, N; Parikh, P ... Dear Sir, Adult T-cell leukemia/lymphoma (ATL) is a neoplastic disease of CD4-positive T lymphocytes. Human T-cell leukemia virus type I (HTLV-I) is critical for the development of ATL. [1] HTLV-I is endemic in Japan. [2] ATL has hardly been reported from India. ATL develops in only 2% ...
Primary mediastinal giant teratocarcinoma
Apr 01, 2008; Singhal, M; Jhavar, D ... Dear Sir, A 25-year-old male presented with right hemi-thoracic chest pain, brassy cough, and progressively worsening dyspnoea for last two months. He developed facial puffiness and edema of both the upper limbs for last one month. Examination revealed mild pallor, distended and ...
Perspectives on QOL in India
Apr 01, 2008; Kazi, R ... Dear Sir, This is a letter in response to an article in your latest issue. [1] This is a nice article on QOL that deserves credit. I would like to congratulate the Editorial team of IJC for taking the initiative in publishing such articles on QOL. The impact of HNC and ...
Meningeal carcinomatosis from pulmonary adenocarcinoma
Apr 01, 2008; Doctor, A; Sharma, S; Maheshwari, M ... Dear Sir, Meningeal carcinomatosis without brain parenchymal involvement is a rare metastatic manifestation of carcinoma lung. CT scan and MRI may help the diagnosis, but a positive cytological examination of the cerebrospinal fluid is confirmatory. Intrathecal chemotherapy with involved ...
Pulmonary artery sarcoma: The hidden truth
Apr 01, 2008; Das, S ... Dear Sir, An important case report on the Pulmonary artery sarcoma was published in the January-March 2008 issue of the journal. [1] I agree with the authors that the pulmonary artery sarcoma is a rare entity but in year 2008 itself, at least eleven articles could be found on medline. It ...
Authors' reply
Apr 01, 2008; Sandhu, A; Yates, T; Kuriakose, P ... Dear Sir, In response to the editorial of our recently published case report "Pulmonary artery sarcoma mimicking a pulmonary embolism", [1] we would first like to thank the Dr. Das [2] for his interest in this case. We agree with his insight that these sarcomas are perhaps not as rare as ...
Observations on the expression of bcg-1 gene in breast tumor and adjacent tissue
Apr 01, 2008; Kumar, V; Srivastava, A; Kumar, V ... Dear Sir, Various clinico-pathological characteristics are evaluated for the management of breast cancer and the predictive value of these variables in determining benefit from endocrine therapy could be further refined by gene expression signatures. [1] Recently it has been shown that ...
A t(X; 18) SYT-SSX2 positive synovial sarcoma in the pelvis of a young adult male: A rare case report with review of literature
Apr 01, 2008; Rekhi, B; Jambhekar, N; Desai, S; Basak, R; Puri, A; Agrawal, M ... Introduction Synovial sarcoma (SS) is defined as a mesenchymal spindle cell tumor, displaying variable epithelial differentiation and is characterized by a specific chromosomal translocation t(X: 18) (p11; q11). [1] It is uncommon, accounts for 5-10% of soft tissue sarcomas and is ...