Indian Journal of Dermatology, Venereology and Leprology back issues from January 2005:
Reporting of drug eruptions: The national pharmacovigilance program
Jan 01, 2005; ... In the daily drudgery of clinical practice, every now and then we come across a patient who is sure that a particular drug is affecting his or her skin in a peculiar way. However, to our brains, trained to recognize common drug eruptions, it seems fantastic that any drug could cause side effects ...
Comparison of two systems of classification of leprosy based on number of skin lesions and number of body areas involved - A clinicopathological concordance study
Jan 01, 2005; ... INTRODUCTION In India and in most endemic countries, for purposes of therapy leprosy patients are classified into paucibacillary (PB) and multibacillary (MB) types on the basis of the number of skin lesions, with five lesions being the determining number.[1] A count of the body areas ...
Serum adenosine deaminase levels in reactional and non-reactional leprosy
Jan 01, 2005; ... INTRODUCTION Adenosine deaminase (ADA), an enzyme of purine metabolism, in part regulates the lymphocytes metabolism and is also important for lymphocytic differentiation and growth.[1] It is present in lymphocytes in high concentration. The level of enzyme in T-lymphocytes varies ...
A study of mortality in dermatology
Jan 01, 2005; ... INTRODUCTION There is a belief among the medical fraternity and the general public that dermatological diseases are not life-threatening and cannot kill the patient, which we know is not true. Moreover, there are very few studies worldwide regarding mortality in dermatology. Most of the ...
High seroprevalence of HSV-1 and HSV-2 in STD clinic attendees and non-high risk controls: A case control study at a referral hospital in South India
Jan 01, 2005; ... INTRODUCTION Both type-specific and non-specific antibodies to herpes simplex virus (HSV) infection develop during the first several weeks following infection and persist indefinitely.[1] Type-specific antibody-based serological tests are better than non-specific antibody-dependent ...
Treatment of keloids and hypertrophic scars
Jan 01, 2005; ... INTRODUCTION Hypertrophic scars and keloids may follow local skin trauma or inflammatory skin disorders like laceration, tattoos, burns, injections, ear-piercing, vaccination, bites, acne, abscess or surgery. They are the consequences of uncontrolled synthesis and deposition of dermal ...
Efficacy of diode laser for treating acne keloidalis nuchae
Jan 01, 2005; ... INTRODUCTION Acne keloidalis nuchae (AK), also known as folliculitis keloidalis, is a chronic inflammatory process involving the hair follicles of the nape of the neck. It is characterized by the presence of papules and pustules arranged in irregularly linear groups just below the ...
Eosinophilic leukemoid reaction associated with carbamazepine hypersensitivity
Jan 01, 2005; ... INTRODUCTION Carbamazepine is a widely used anticonvulsant which often causes adverse drug eruptions. Carbamazepine hypersensitivity reactions may mimic viral infections, glandular fever, or pseudo-lymphoma.[1],[2],[3] Eosinophilia may occur as a part of carbamazepine hypersensitivity ...
Fatal disseminated strongyloidiasis in patients on immunosuppressive therapy: Report of two cases
Jan 01, 2005; ... face=+Italic; Strongyloides stercoralisface=-Italic; is distributed worldwide in the tropics and subtropics.[1] The adult female lives in the small intestine. In the majority of patients the parasite load is low and the patient is free of any symptoms. Corticosteroid therapy and malnutrition ...
Pigmented xerodermoid - Report of three cases
Jan 01, 2005; ... INTRODUCTION Xeroderma pigmentosum (XP) is a rare autosomal recessive disease in which the patient typically lacks the normal capacity to repair UV radiation-damage to DNA.[1] XP is a genetically and clinically heterogeneous disease. Genetically, there are at least eight subtypes ...
Successful treatment of scleromyxedema with dexamethasone cyclophosphamide pulse therapy
Jan 01, 2005; ... Sir, Scleromyxedema is an uncommon disorder of mucin deposition associated with paraproteinemia, especially IgG gammopathy.[1] Its pathogenesis is still uncertain, but there are various hypotheses, one of which suggests that some circulating factor, not the paraprotein, might be ...
Generalized hypopigmentation due to imatinib: A fairness boon?
Jan 01, 2005; ... Sir, Imatinib (STI571, Glivec©) is a new selective tyrosine kinase inhibitor that is very useful in the treatment of chronic myelogenous leukemia (CML) and gastrointestinal stromal tumors (GIST). More side effects are being reported with its increasing use. We report generalized ...
Amiodarone-induced angioedema: Report of two cases
Jan 01, 2005; ... Sir, Amiodarone, a class II long-acting anti-arrhythmic, capable of blocking both α and β -adrenoceptors is an iodine-containing highly lipophilic benzofuran derivative.[1],[2] Adverse reactions are common and are duration-dependent. Frequent reactions include nausea and other ...
Sparfloxacin induced blue/black discoloration of all nails: Report of three cases
Jan 01, 2005; ... Sir, Discoloration of nails is usually seen as an adverse reaction to drugs.[1] Pigmentation can occur either in the nail plate or vascular nail bed. The term face=+Italic; chromonychiaface=-Italic; indicates an abnormality in color of the substance and / or the surface of the nail ...
Onycholysis: An unusual side effect of roxithromycin
Jan 01, 2005; ... Sir, Onycholysis is a separation of distal part of nail plate from its nail bed and/or lateral supporting structures. One or more nails may be affected. The affected nail plate itself is smooth and firm. The separated portion is usually in the shape of half moon and appears white due to ...
Hydroxyurea induced non-healing leg ulcer
Jan 01, 2005; ... Sir, Hydroxyurea is a commonly used chemotherapeutic agent in chronic myeloid leukemia in India. Rarely its long term use can lead to leg ulceration. Such an ulcer generally does not respond to the usual measures but heals when hydroxyurea is stopped. A 40 year old man, case of ...
HIV and HbsAg seroprevalence in commercial sex workers in Raipur (Chhattisgarh) area
Jan 01, 2005; ... Sir, Heterosexual intercourse is the dominant mode of HIV transmission in most parts of the world. Commercial sex workers (CSWs) are associated with high incidence of STDs. HIV seroprevalence in CSWs in Mumbai had crossed 69% in 1995.[1] HIV and hepatitis B virus (HBV) share a common ...
Bullous scabies in a patient on anticancer therapy
Jan 01, 2005; ... Sir, Scabies is highly contagious and intensely pruritic skin infestation caused by mite face=+Italic; Sarcoptes scabiei var hominisface=-Italic; . Bullous scabies is a rare manifestation of scabies which is occasionally seen in the immunosuppressed.[1] We report a case of bullous ...
Bullous systemic lupus erythematosus: Response to dapsone in two patients
Jan 01, 2005; ... Sir, Bullous systemic lupus erythematosus (SLE) is a transient autoimmune bullous disease that occurs in established cases of SLE. Some authors use this term for all subepidermal autoimmune bullous conditions in SLE, whereas others use it for conditions where dermal antigens are ...
Lines of Blaschko
Jan 01, 2005; ... INTRODUCTION The lines of Blaschko represent a pattern assumed by many different nevoid and acquired skin diseases on the human skin and mucosae.[1] These lines do not correspond to any known nervous, vascular or lymphatic structures but represent the developmental growth pattern of the ...
Web sites on adverse drug reactions and drug interactions
Jan 01, 2005; ... Adverse effects are the prime health hazards of prescription drugs. In order to manage an adverse drug reaction it is important to be aware of all possible drug reactions and drug interactions. However, given the current scenario of a new drug a day, it is impossible to keep track of all reports ...
Generalised yellowish papular eruption in a child
Jan 01, 2005; ... A 3 year old male child presented with multiple asymptomatic flat yellowish waxy papules and plaques over face [Figure:1], trunk, dorsa of hands [Figure:2] since twentieth day of life. At the age of two weeks, the child had developed generalised erythematous rash that had persisted for a few ...
Dr. Sharat C. Desai (11.06.1917 - 19.08.2004)
Jan 01, 2005; ... Dr. Sharat C. Desai (11.06.1917 - 19.08.2004) [Figure:1] On August 19 this year, Indian dermatology lost a pioneer, Dr. Rekha Sheth her father, and I my mentor. The day is well marked in my diary. Dr. Sharat Chotubhai Desai was born in Valsad district of Gujarat. He lost his ...
Dr. L. K. Bhutani (05.09.1936 - 24.07.2004)
Jan 01, 2005; ... Dr. L. K. Bhutani (05.09.1936 - 24.07.2004) [Figure:1] Professor Bhutani died unexpectedly and prematurely on July 24, 2004, a few weeks short of his 68th birthday. He had been diagnosed with chronic lymphoid leukemia a year earlier that was consciously left untreated. In May 2004, he ...
Dexamethasone-cyclophosphamide pulse therapy in systemic lupus erythematosus
Jan 01, 2005; ... INTRODUCTION Systemic lupus erythematosus (SLE) is a systemic disease characterized by the association of immunological abnormalities with pathological changes affecting a number of organ systems.[1] A range of auto-antibodies is found in SLE, although some of these are disease specific ...