Recently added articles from Indian Journal of Pharmacology:
Polyamines: Potential anti-inflammatory agents and their possible mechanism of action
May 01, 2008; Lagishetty, Chakradhar; Naik, Suresh ... Introduction The polyamines putrescine, spermidine and spermine are aliphatic polycations derived from ornithine and play vital physiological roles. [1] Polyamines being cationic in nature bind to the negatively charged nucleic acids of the cell membrane surface and are thus involved in ...
Evaluation of antidepressant activity of tramadol in mice
May 01, 2008; Tayal, Vandana; Kalra, Bhupinder; Chawla, Shalini ... Introduction Tramadol is a synthetic centrally acting opioid analgesic used mainly for the treatment of moderate to severe pain. [1] It is a weak μ opioid receptor agonist and also produces analgesia by inhibiting uptake of norepinephrine and serotonin. [1] Tramadol causes ...
The concept of personal drugs in the undergraduate pharmacology practical curriculum
May 01, 2008; Khilnani, Gurudas ... I have read the thought provoking research letter by Dr Parmar and Jadav on The concept of personal drugs in the undergraduate pharmacology practical curriculum. [1] I have the following comments to share with the readership of the IJP. The concept of P-drug for the undergraduate ...
Trichosanthes cucumerina Linn. improves glucose tolerance and tissue glycogen in non insulin dependent diabetes mellitus induced rats
May 01, 2008; Kirana, H; Srinivasan, B ... Introduction Non Insulin Dependent Diabetes Mellitus (NIDDM) also called as type 2 diabetes is a complex metabolic disorder that involves abnormalities in both insulin secretion and action at peripheral tissues. [1] It is a more prevalent form of diabetes and responsible for 90% of the ...
Immunomodulatory effect of Tinospora cordifolia extract in human immuno-deficiency virus positive patients
May 01, 2008; Kalikar, M; Thawani, V; Varadpande, U; Sontakke, S; Singh, R; Khiyani, R ... Introduction Acquired immuno-deficiency syndrome (AIDS) is a fatal illness caused by human immuno-deficiency virus (HIV), which breaks down the host immune system, leaving the subject vulnerable to life-threatening opportunistic infections, neurological disorders and malignancies. Once ...
Evalution of anti-ulcer activity of Polyalthia longifolia (Sonn.) Thwaites in experimental animals
May 01, 2008; Malairajan, P; Gopalakrishnan, Geetha; Narasimhan, S; Veni, K ... In traditional medicines various herbal preparations are being used for treating duodenal ulcers. [1] Polyalthia longifolia (Sonn.) Thwaites (PL) (Family: Annonaceae) is a tall handsome evergreen tree and it is cultivated all over India. The plant has been used in traditional system of medicine ...
In vivo antimalarial activity of ethanolic leaf extract of Stachytarpheta cayennensis
May 01, 2008; Okokon, Jude; Ettebong, Ette; Antia, Bassey ... Introduction Stachytarpheta cayennensis (L.C. Rich) Vahl is a weedy (and sometimes perennial) herbaceous plant from the Verbenaceae family commonly called Brazilian tea. Two common very similar species of Stachytarpheta cayennensis grow in the tropics and are use interchangeably (and ...
Four decades of Indian Journal of Pharmacology: An overview
May 01, 2008; Patel, Varsha ... Indian Journal of Pharmacology (IJP) will step into the fifth decade in 2009. It is customary to celebrate 'jubilee' years with some sense of gratification and achievement; a time for looking back to take the account of progress made along with a note of milestones that are yet to be achieved ....
Principles of thesis writing
May 01, 2008; Sood, Rita ... Edited by Tejinder Singh, Dheeraj Shah and Piyush Gupta 93 pp, Rs. 150/- Indian Academy of Pediatrics, Jaypee Brothers Medical Publishers (P) Ltd., 2008 ISBN: 978-81-8448-290-4 This is the first edition of this book, authored by the three editors, all of whom are ...
Novel immunobiologics for psoriasis
May 01, 2008; Ghosh, Nilanjan; Singh, P; Kumar, Vikas ... Introduction Psoriasis is an immune mediated genetic papulosquamous skin disorder which affects approximately 3% of world population. A substantial proportion of patients with psoriasis may develop a form of inflammatory arthritis known as psoriatic arthritis which contributes ...
Neglected tropical diseases: Need for sensitization of medical students
May 01, 2008; Gautam, C; Bhanwra, Sangeeta ... The neglected tropical diseases are a set of thirteen disabling conditions that are among the most common chronic infections in the developing countries like India. About 350 million people are already disabled or severely impaired due to them. Over 3 billion children, women and men are at risk ...
Comparative evaluation of some flavonoids and tocopherol acetate against the systemic toxicity induced by sulphur mustard
May 01, 2008; Vijayaraghavan, R; Gautam, Anshoo; Sharma, Manoj; Satish, H; Pant, S; Ganesan, K ... Introduction Sulphur mustard (SM) chemically, bis 2-chloroethyl sulphide is listed in the Schedule 1 of the Chemical Weapons Convention (CWC). One of the important molecular targets of SM is DNA. SM damages the DNA mainly by alkylating and cross linking the purine bases. [1] At the ...