Recently added articles from Indian Journal of Pharmacology:
Assessment of prescription pattern at the public health facilities of Lucknow district
Nov 01, 2008; ... Introduction Drugs play an important role in protecting, maintaining and restoring health. Prescription writing is a science and an art, as it conveys the message from the prescriber to the patient. The treatment of diseases by the use of essential drugs, prescribed by their generic ...
Prescribing knowledge and skills of final year medical students in Nigeria
Nov 01, 2008; ... Introduction Evidence of poor prescribing is abundant in Nigeria.[1] Antimalarials and antibiotics are prescribed for children, with little regard for resistance and adverse drug reaction development. [1],[2] Prescription errors are very common, [3],[4] especially with fresh doctors. [5] ...
41 st Annual Conference
Nov 01, 2008; ... I wish all the participants of the 41 st Annual Conference of the Indian Pharmacology Society a great success in all their scientific endeavors. This time, it's being held at AIIMS, New Delhi. The conference also coincides with the International Conference on Translational Pharmacology. It's ...
Antidiabetic activity of flower buds of Michelia champaca Linn.
Nov 01, 2008; ... Introduction Diabetes mellitus, a chronic metabolic disorder, has now become an epidemic, with a worldwide incidence of 5% in the general population. The number of people suffering from diabetes has soared to 246 million and the disease now kills more people than AIDS. [1] Decreased ...
The effect of sodium valproate on the biochemical parameters of reproductive function in male albino Wistar rats
Nov 01, 2008; ... Introduction Clinically, the most prominent effects of anticonvulsant medications on endocrine function are those on sexuality and the reproductive function. The hepatic enzyme-inducing antiepileptic drugs (AEDs) - phenobarbital, primidone, phenytoin, and carbamazepine - may all ...
Phase 0 - Microdosing strategy in clinical trials
Nov 01, 2008; ... Introduction Human drug development is a dynamic process that keeps pace with the recent advances within the pharmaceutical analytical labs, combined with a precise understanding of the integrated pharmacokinetic-pharmacodynamic-pharmacogenomic drug profile. New drugs are a great need ...
The effect of Allium sativum on ischemic preconditioning and ischemia reperfusion induced cardiac injury
Nov 01, 2008; ... Introduction Ischemic injury is one of the prime causes of cardiovascular mortality and in several clinical situations, early reperfusion has shown to improve myocardial pump function. [1] However, reperfusion has its own inherent limitation by inflicting reperfusion injury. [2] An ...
Gastroprotective effect of Benincasa hispida fruit extract
Nov 01, 2008; ... Introduction Benincasa hispida (Thunb) Cogn. (Family: Cucurbitaceae) is commonly known as Bhuru Kolu or Safed Kolu (Gujarati), Petha (Hindi), white pumpkin or wax gourd or ash gourd (English), and Kushmanda (Sanskrit). Fruits of this plant are traditionally used as a laxative, diuretic, ...
Infertility improved by etanercept in ankylosing spondylitis
Nov 01, 2008; ... Introduction TNF-α is a cytokine exerting a wide range of cellular effects. In testis, TNF-α is produced by germ cells and it has a role in the regulation of spermatogenesis. [1] TNF-α levels are usually low in seminal plasma, but they tend to increase in inflammatory ...
Antioxidant potential of the methanol-methylene chloride extract of Terminalia glaucescens leaves on mice liver in streptozotocin-induced stress
Nov 01, 2008; ... Introduction Diabetes mellitus is a major endocrine disorder and growing health problem in most countries. [1] Diabetes manifested by experimental animal models exhibit high oxidative stress due to persistent and chronic hyperglycemia which increases the generation of free radicals, ...
Ocular adverse effects of Topiramate: Two case reports
Nov 01, 2008; ... Introduction Topiramate has been approved for use as an add-on therapy or monotherapy for resistant partial seizures and generalized seizures. Its other uses include migraine prophylaxis, bipolar and post-traumatic stress disorders, and neuralgias. [1] Its antiepileptic activity is ...
Authors' reply
Nov 01, 2008; ... Sir, I thank you for your keen interest and comments [1] on the correspondence, 'The concept of personal drugs in the undergraduate pharmacology practical curriculum.' [2] I have to submit the following in reply: The usual recommended dose of tinidazole is 2 g/day for three days ....
The concept of personal drugs in the undergraduate pharmacology practical curriculum
Nov 01, 2008; ... This is with reference to the correspondence, 'The concept of personal drugs in the undergraduate pharmacology practical curriculum'. [1] We would like to highlight the following facts: The usual dose recommendation of tinidazole in acute amoebic dysentery is 2 gm/day for 3 days. [2] The ...
P-drug concept and the undergraduate teaching
Nov 01, 2008; ... This is in response to the letter by Khilnani G titled "The concept of personal drugs in the undergraduate pharmacology practical curriculum." [1] For sometime now, there is an ongoing discussion on P-drug concept. Various authors have suggested that undergraduates should be sensitized toward ...
An overview of the articles published in the Indian Journal of Pharmacology during the year 2007
Nov 01, 2008; ... On the arrival of the sixth issue (December 2007), the Indian Journal of Pharmacology (IJP) had completed its journey for the year 2007 under the new editorial team headed by Dr. Shiv Prakash, the present chief editor of the IJP. In this issue of the IJP (Indian J Pharmacol ...
Writing an effective manuscript: Editor's perspective
Sep 01, 2008; ... Writing a research article and getting it published is an appropriate and acceptable means of reporting new information to the scientific community. It is also the stepping stone for the professional career of a research scientist. However, scientific writing is not all that easy! The journey of ...
Role of pharmacogenomics in drug discovery and development
Sep 01, 2008; ... Introduction In the process of drug discovery, most drug compounds that act on the target during the early phases fail to emerge as therapeutic agents. This could be due to unexpected failure of efficacy or occurrence of adverse events. Pharmacogenetics involves the study of single gene ...
Burn wound healing property of Cocos nucifera: An appraisal
Sep 01, 2008; ... Introduction Burn can be defined as tissue damage caused by a variety of agents such as heat, chemicals, electricity, sunlight, or nuclear radiation. The most common are burns caused by scalds, building fires, and flammable liquids and gases. Every year, about two million people receive ...
In vitro antioxidant activity of pet ether extract of black pepper
Sep 01, 2008; ... Introduction The importance of the reactive oxygen species (ROS) has attracted increasing attention over the last decade. Reactive oxygen species includes free radicals such as superoxide anion radicals (O 2 -· ), hydroxyl radicals (OH¯ ), non free radicals such as H 2 O 2 and singlet ...
The effect of aqueous extract of Embelia ribes Burm on serum homocysteine, lipids and oxidative enzymes in methionine induced hyperhomocysteinemia
Sep 01, 2008; ... Introduction Hyperhomocysteinemia is a risk factor for coronary atherosclerotic vascular disease, stroke, and venous thrombosis. It has been associated with Alzheimer's disease and vascular dementia. [1],[2],[3],[4] Although its pathophysiological mechanisms are complex and not fully ...