Indian Journal of Pharmacology back issues from November 2004:
The M. D. (Pharmacology) examinations: A call for better standards
Nov 01, 2004; ... The MD examination in pharmacology has always been an event which has evoked great trepidation in the candidates, pride in those selected as examiners, a sense of challenge to host it uneventfully in those heading the home departments, cunning in the technicians and assistants to help the ...
Hypertension, cancer and angiogenesis: Relevant epidemiological and pharmacological aspects
Nov 01, 2004; ... Introduction Hypertension is the most common cardiovascular disease and a major public health problem in both developed and developing countries.[1] Hypertension is a major risk factor for stroke, coronary heart disease, cardiac failure and renal failure. Prevention and treatment of ...
Possible anorectic effect of methanol extract of Benincasa hispida (Thunb). Cogn, fruit
Nov 01, 2004; ... Introduction face=+Italic; Benincasa hispidaface=-Italic; (Thunb.) Cogn (Cucurbitacecae) fruit is widely used as a vegetable in India and other tropical countries. The fruit face=+Italic; B. hispidaface=-Italic; is an important ingredient of "Kusmanda lehyam" (Ayurvedic medicine) which ...
Calcium channel blockers reduce inflammatory edema in the rat: Involvement of the hypothalamus-pituitary-adrenal axis
Nov 01, 2004; ... Introduction Calcium movement is an important factor in the activation of cells responsible for inflammation.[1] Calcium does this by releasing the inflammatory mediators[2],[3],[4] or by the activation of the plasma membrane or intracellular enzymes.[5] It has been reported that calcium ...
Pyrogallol: A novel tool for screening immunomodulators
Nov 01, 2004; ... Introduction While screening the immunomodulatory activity, most of the studies employ agents like cisplatin, cyclophosphamide, or corticosteroids in order to induce the immunosuppression in the experimental animals.[1] These agents are also known to generate free radicals in the ...
Comparison of the clinical efficacy of three brands of warfarin
Nov 01, 2004; ... Introduction Warfarin is a common anticoagulant which is used in a variety of clinical settings. The drug is vital to many patients at increased risk of thromboembolic complications, and is often prescribed for patients with artificial heart valves, arrhythmias or other conditions that ...
Effect of nabumetone on the renal function in conscious and anesthetized rats
Nov 01, 2004; ... Introduction Non-steroidal antiinflammatory drugs (NSAIDs) produce deleterious side-effects on renal function, particularly when there is pre-existing renal disease or during hemodynamically stressful situations.[1] These effects have been attributed to the inhibition of prostaglandin ...
Book Review
Nov 01, 2004; ... face=+Bold; MCQ's IN PHARMACOLOGY with brief explanatory noteface=-Bold; for correct answer by Chandrakanta Chouhan. Published by AITBS Publishers &Distributors (Regd.), Delhi, India. First Edition, 2004. ISBN 81-7473-253-5. Pages 306. (Price: Rs. 150/-). This book as the author ...
Study of the antinociceptive activity of fluoxetine and its interaction with morphine and naloxone in mice
Nov 01, 2004; ... Introduction Pain is an unpleasant sensation, and a very common phenomenon. There is no doubt that pain acts as a warning signal against disturbances either in the body or in the external environment of an individual. The principal objective of the treatment of pain is to remove or ...
Effect of shilajit on blood glucose and lipid profile in alloxan-induced diabetic rats
Nov 01, 2004; ... Introduction Diabetes mellitus is a major public health problem in the developed as well as developing countries. It is ranked seventh among the leading causes of death, and third when all its fatal complications are taken into account. Large-vessel atherosclerosis is the most common ...
Antinociceptive and antiinflammatory effects of Centella asiatica
Nov 01, 2004; ... Introduction face=+Italic; Centella asiaticaface=-Italic; (CA) of the family Umbelliferae is commonly found in parts of India, Asia and the Middle East. It is known as 'Pegaga' in Malaysia, 'Luei Gong Gen' or 'Tung Chain' in China, 'Vallarai' in Tamil Nadu (India) and 'Daun Kaki Kuda' ...
Antihypertensive effect of newly synthesized acyl amino substituted propanolamine derivatives, DPJ 890 and DPJ 955 in rats
Nov 01, 2004; ... Sir, Hypertension described as a 'silent killer' increases the incidence of cardiovascular diseases. blockers have been widely used since more than four decades for the treatment of hypertension. However these drugs are contraindicated in asthmatics and diabetics.[1] In order to ...
Effect of curcumin on triton WR 1339 induced hypercholesterolemia in mice
Nov 01, 2004; ... Sir, Curcumin (diferuloylmethane), a major component of turmeric, is a yellow pigment obtained from rhizomes of face=+Italic; Curcuma longa,face=-Italic; is commonly used in Indian cuisine as a spice and food-coloring agent. Curcumin and its analogues have a variety of physiological and ...
Prescribing pattern for outpatients in government hospitals in Jaipur
Nov 01, 2004; ... The WHO-India program on the Rational use of Drugs, which has been going on for almost 20 years in India aims at promoting rational prescribing through a multi-pronged strategy which includes interventions to correct drug use problems, adoption of Essential Drug List (now called the Essential ...
Experiences regarding modification of the teaching and evaluation pattern in practical pharmacology
Nov 01, 2004; ... Sir, In a previous editorial in the IJP[1] the urgent need for massive and sweeping revision of the medical curriculum related to pharmacology was pointed out. I believe that teachers at various institutions may already be making the efforts, but various factors may prevent them from ...
A comparative study of two evaluation techniques in pharmacology practicals: Conventional practical examination versus objective structured practical examination
Nov 01, 2004; ... Sir, Evaluation is a systematic process that consists of finding out the extent to which educational objectives have been achieved by the students.[1],[2] Any evaluation process must thus be directly related to the educational objectives. The present system of assessing the students' ...
The other side of OSPE
Nov 01, 2004; ... Sir, Pharmacologists in India have been using Objective Structured Practical Examination (OSPE) as a method of evaluation since the early nineties.[1] It has been often touted as a good substitute for the conventional method of practical examinations since it is more objective. At the ...
Trastuzumab
Nov 01, 2004; ... Trastuzumab is a DNA recombinant-derived immune protein and the first humanized monoclonal antibody, which is approved by FDA for the treatment of HER 2/neu positive metastatic breast cancer. Trastuzumab in combination with paclitaxel is indicated in patients with metastatic breast cancer whose ...
BioTech
Nov 01, 2004; ... Modern biotechnology has transcended the confines of its traditional domain of technology based on biology to a more modern one that includes the use of genetically altered microorganisms for producing therapeutic substances, transgenic animals and plants, genetically altered mammalian cells and ...
Prof. Asis Kumar Nag Chaudhury (07.07.1949 - 19.03.2004)
Nov 01, 2004; ... Prof. Asis Kumar Nag Chaudhury 07.07.1949 - 19.03.2004 [Figure:1] With great shock and grief, we record the sudden and untimely demise on March 19, 2004, of Prof. Asis Kumar Nag Chaudhury of the Division of Pharmacology, Department of Pharmaceutical Technology, Jadavpur ...