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Journal of AOAC International articles

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Separation and determination of clenbuterol by HPLC using a vancomycin chiral stationary phase.(DRUG FORMULATIONS AND CLINICAL METHODS)(high performance liquid chromatography)(Report)

May 01, 2009; ... Clenbuterol is chemically known as 4-amino-3, S-dichloro-[alpha][(1, 1-dimethyl) amino]-methyl-benzenemethanol (1). There is one chiral center in its molecule; the R-(-), S(+)-clenbuterol, and S-(-)-atenolol configurations are shown in Figure 1. Chirality is a prominent feature ...

Automated chemiluminometric screening of counterfeit drugs of the antituberculosis agent pyrazinamide.(DRUG FORMULATIONS AND CLINICAL METHODS)(Report)

May 01, 2009; ... At this time, the quality of drugs and therefore their effectiveness and safety are less and less certain, especially for the poorest populations, who are attracted by low-priced drugs sold through venues other than pharmacies. Recent years have seen an increase in the prevalence of ...

Identification of volatile compounds in chrysanthemum morifolium by microwave distillation solid-phase microextraction coupled with GC/MS.(DRUG FORMULATIONS AND CLINICAL METHODS)(gas chromatography, mass spectrometry)(Report)

May 01, 2009; ... Crysanthemum morifolium (CM) is a perennial herb native to China, where it has been cultivated for over 2000 years. It is an important plant because of its aesthetic and medicinal value. The dried flowers of CM known as Juhua in China, are widely used as health food and folk medicine. They ...

Optimization of the treatment of wheat samples for the determination of phytic acid by HPLC with refractive index detection.(FOOD COMPOSITION AND ADDITIVES)(high performance liquid chromatography)(Report)

May 01, 2009; ... Phytic acid (inositol hexakisphosphate, [InsP.sub.6]) is widely distributed in commonly consumed foods. It is found in high concentrations in the seeds of grains, pulses, and oleaginous products, and in lesser amounts in tubers and garden produce. The amount of phytate in food has been of ...

Development and validation of an LC method for simultaneous determination of amiloride hydrochloride and hydrochlorothiazide in human urine.(DRUG FORMULATIONS AND CLINICAL METHODS)(liquid chromatography)

May 01, 2009; ... Diuretics are an indispensable group of therapeutics used to regulate the excretion of water and salts. They are often used in the treatment of hypertension, chronic and acute heart failure, and cirrhosis. Moreover, diuretics have been misused in sports by competitors to reduce weight ...