Recently added articles from Journal of Drugs in Dermatology:

Increase in collagen turnover induced by intradermal injection of carbon dioxide in rats.

Mar 01, 2008; Ferreira, Julio Cesar Tavares ... Introduction Human tissue changes with age. In the skin, these modifications are more easily recognized. (1,2) The modifications to the collagen and elastin system cause wrinkles, atrophy, grooves, ptosis, and laxity. These are the most evident signs of old skin, (3-6) which can ...

Dermatological implications of skeletal aging: a focus on supraperiosteal volumization for perioral rejuvenation.

Mar 01, 2008; Vleggaar, Danny ... Introduction Facial beauty and attractiveness are important cross-cultural social concepts as they tend to dictate how individuals are judged and treated. (1) Research has shown that facial beauty is perceived and processed rapidly by the brain and this perception biases ...

Botulinum toxin type A versus topical 20% aluminum chloride for the treatment of moderate to severe primary focal axillary hyperhidrosis.

Mar 01, 2008; Flanagan, Katherine H. ... Introduction Severe hyperhidrosis affects 2.8% of the population and can be socially unacceptable and emotionally devastating. (1) Approximately 1.4% of the US population has axillary hyperhidrosis, with one-third having severe axillary hyperhidrosis, ie, sweating that is barely ...

Histological and clinical studies on the effects of low to medium level infrared light therapy on human and mouse skin.

Mar 01, 2008; Kameyama, Koichiro ... Introduction Phototherapy of the skin has been used for many years, but its exact mechanism of action is still not clear. (1) Nonablative laser or intense pulsed light (IPL) therapies have been reported to require thermal damage of the dermis. (2,3) Thermal damage denatures the ...

Lip augmentation and rejuvenation using a novel, porcine collagen-derived filler.

Mar 01, 2008; Landau, Marina ... Introduction There are no universal ideas about the aesthetics of lips, as they vary with cultural beliefs, time, and individual preferences. (1) In an attempt to improve their appearance, many women, prompted by the changes that occur with aging, will seek to augment their ...

Utilization of narrow-band ultraviolet light B Therapy and Etanercept for the Treatment of Psoriasis (UNITE): efficacy, safety, and patient-reported outcomes.

Mar 01, 2008; Kircik, Leon ... Introduction Psoriasis is a chronic, systemic, debilitating inflammatory disease involving the skin, and potentially the joints in patients with psoriatic arthritis. (1) It has an important impact on patient wellbeing, potentially resulting in embarrassment, self-consciousness, ...

A pilot study to determine the safety and efficacy of monochromatic excimer light in the treatment of vitiligo.

Mar 01, 2008; Chimento, Stacy M. ... Introduction Vitiligo is a chronic depigmentary disorder characterized by the loss of melanin and decreased melanocytes in the epidermis of affected skin. This defect results in well-circumscribed white macules or patches, which tend to expand over time. Classified as focal, ...

Hydrocortisone butyrate 0.1% lotion in the treatment of atopic dermatitis in pediatric subjects.

Mar 01, 2008; Matheson, Robert ... Introduction Topical corticosteroids have become the cornerstone of treatment for a variety of inflammatory dermatoses, including atopic dermatitis (AD), eczema, and psoriasis. A wide selection of topical corticosteroid products is available and the potency of these formulas ...

Skin rejuvenation in Asian skin: the analysis of clinical effects and basic mechanisms of intense pulsed light.

Mar 01, 2008; Feng, Yujie ... Introduction Photoaging is the result of chronic ultraviolet (UV) light exposure characterized by both epidermal and dermal skin changes. The visible signs of photodamage include coarse skin texture, wrinkles, pigmentation alterations, telangiectasias, premalignant and actinic ...

Fast and easy treatment for reduction of the Tyndall effect secondary to cosmetic use of hyaluronic acid.(CASE REPORTS)

Mar 01, 2008; Douse-Dean, Tracee ... Introduction Evaluation of the aging face includes the assessment of volume loss due to thinning skin, fat atrophy, and fat pad descent and protrusion. Today's treatment options include a variety of filler substances. One common product that is used for facial contouring and ...

Erythromelalgia of the ears: an unusual variant and response to therapy.(CASE REPORTS)(Case study)

Mar 01, 2008; Berk, David R. ... Introduction Erythromelalgia is an idiopathic condition characterized by episodes of erythematous, warm, burning acral skin, which is exacerbated by heat and relieved by cold. Erythromelalgia can be primary or secondary to various conditions including myeloproliferative ...

Basal cell carcinoma of the vulva presenting as unilateral pruritus.(CASE REPORTS)

Mar 01, 2008; Saini, Ritu ... Introduction Basal cell carcinoma (BCC) is the most common human malignancy and has been reported to account for a vast majority of all nonmelanoma skin cancers. Although it may occur in association with certain rare genetic disorders such as Gorlin (basal cell nevus), Rombo, ...

Inguinal hyperhidrosis misdiagnosed as urinary incontinence: treatment with botulinum toxin A.(CASE REPORTS)(Case study)

Mar 01, 2008; Woolery-Lloyd, Heather ... Case Report A 34-year-old Hispanic female presented with a chief complaint of excessive wetness in the underpants. The patient had a history of excessive sweating on her nose as well. Her condition had been imminent for 20 years with onset beginning around puberty, with the ...

2008 dermatology conferences and conventions.(Calendar)

Mar 01, 2008 ... January 7th Annual Caribbean Dermatology Symposium January 15-19, 2008 St Thomas, US Virgin Islands www.caribederm.org American Society of Cosmetic Surgery 24th Annual Scientific Meeting (ASCS) January 17-20, 2008 ...

Somatic stem cells in dermatology.(LASER AND COSMETIC NEWS)

Mar 01, 2008; Alexiades-Armenakas, Macrene ... The reprogramming of somatic stem cells derived from adult human skin into a pluripotent stem cell state has recently been achieved. Fibroblasts isolated from adult human skin were transduced using retroviral vectors carrying 4 key transcription factors: Oct4, Sox2, c-Myc and Klf4 or Oct4, ...

Cutaneous clues to drug addiction.(NEWS, VIEWS, AND REVIEWS)

Mar 01, 2008; Bergstrom, Kendra Gail ... Introduction Drug addiction may be suspected or diagnosed on the basis of skin findings alone. The astute dermatologist may recognize cutaneous patterns, and characteristic skin changes, including burns, scars, or other reaction patterns, suggesting illicit drug use and offer a ...

Flo-Pred approved by the FDA.(PIPELINE PREVIEWS)(food and drug administration)(Brief article)

Mar 01, 2008; Heller, Marissa ... Taro Pharmaceutical Industries Ltd recently announced that the FDA has granted approval to a new drug application for Flo-Pred[TM] (prednisolone acetate oral suspension). Flo-Pred will be available as the equivalent of 5 mg/5 ml and 15 mg/5 ml prednisolone. This new product uses Taro's ...

Over-the-counter cetirizine hydrochloride tablets.(PIPELINE PREVIEWS)(Brief article)

Mar 01, 2008; Heller, Marissa ... Perrigo Company recently reported that the FDA has granted final approval for the manufacturing and marketing of over-the-counter cetirizine hydrochloride ...

Phase III trial for Isolagen Therapy completed.(PIPELINE PREVIEWS)(Brief article)

Mar 01, 2008; Heller, Marissa ... Isolagen, Inc has announced that injection treatments have been completed in its phase III double-blind, randomized, placebo-controlled, clinical trials: IT-A-005 and IT-A-006. All patients who have completed treatments may now advance to the follow-up period of the study. These trials ...

Microcyn[R] for mildly infected diabetic foot ulcers.(PIPELINE PREVIEWS)

Mar 01, 2008; Heller, Marissa ... The phase II clinical study, which evaluated Microcyn[R] Technology for the treatment of mildly infected diabetic foot ulcers, was recently completed. This phase II randomized, controlled trial, which was undertaken by Oculus Innovative Sciences Inc, enrolled a total of 67 patients. ...