Recently added articles from Journal of Postgraduate Medicine:
End of life care: Issues and challenges
Jul 01, 2008; Yeolekar, M; Mehta, S; Yeolekar, A ... Advances in medical technology, diagnostics, transplantations, antibiotic therapy, and critical care have created bioethical dilemmas that confront physicians while dealing with terminally ill patients who are unlikely to survive. Clinicians tend to be less formally trained in providing good ...
Temporomandibular joint skeletal morphology in children and adults
Jul 01, 2008; Kurita, H ... Characteristic bone profile of the temporomandibular joint (TMJ) develops and grows up to late teenage years. [1] TMJ bone structures alter their morphology according to functional and pathological conditions throughout life. In this study, differences in TMJ skeletal morphology between children ...
Undergraduate medical students' research in India
Jul 01, 2008; Deo, M ... In India, medical education has remained more or less static, and research is in a very poor state. Against this backdrop, the idea of promoting research culture at the undergraduate level may look very unrealistic. Yet, as discussed below, there is a silver lining. Students seeking admission to ...
A comparative study of the skeletal morphology of the temporo-mandibular joint of children and adults
Jul 01, 2008; Meng, F; Liu, Y; Hu, K; Zhao, Y; Kong, L; Zhou, S ... The anatomical morphology of skeletal structures of the temporo-mandibular joint (TMJ), which include the glenoid fossa and condyle undergoes remodeling throughout life. Several studies dealing with the TMJ skeletal morphology in adults [1],[2],[3],[4],[5],[6],[7] have been reported. However, ...
Emerging extra-intestinal infections with Aeromonas hydrophila in coastal region of southern Karnataka
Jul 01, 2008; Mukhopadhyay, C; Chawla, K; Sharma, Y; Bairy, I ... The genus Aeromonas has become an increasingly troublesome group to physicians and microbiologists by virtue of its changing phylogenetic relationships, evolving taxonomy and controversial role in certain diseases. [1] These short gram-negative rods with rounded ends are facultative anaerobes ....
Fungal encephalitis following bone marrow transplantation: Clinical findings and prognosis
Jul 01, 2008; Teive, HAG; Carsten, ALM; Iwamoto, F; Almeida, S; Munhoz, R; Werneck, L; Medeiros, C; Pasquini, R ... Several factors are responsible for the severe suppression of cell-mediated immunity in subjects receiving hematopoietic stem cell transplantation (HSCT). These include: the underlying disease, receipt of pre-transplant chemotherapy and radiotherapy, graft-versus-host disease (GVHD) and its ...
Recurrence of primary hyperoxaluria: An avoidable catastrophe following kidney transplant
Jul 01, 2008; Madiwale, C; Murlidharan, P; Hase, N ... Primary hyperoxaluria (PHO) Types 1 and 2 are rare autosomal recessive disorders, characterized by oxalate overload due to deficiency of the liver enzymes alanine glyoxalate aminotransferase (AGT) and D-glycerate dehydrogenase respectively. [1] Type 1 PHO occurs in 0.11 to 0.26 per 100,000 ...
Massive upper GI bleeding: A rare complication of Zenker's diverticulum
Jul 01, 2008; Haas, I; Gutman, M; Paran, H ... Bleeding from a Zenker's diverticulum is rare and since documented cases in the literature are very few, no guidelines exist for the management of this potentially life-threatening condition. The pathophysiology of the ulceration is also unknown. We present a case of acute massive bleeding in a ...
Primary gastrointestinal mucormycosis in an immunocompetent person
Jul 01, 2008; Prasad, B Shiva; Shenoy, A; Nataraj, K ... Mucormycosis is the second most common mold after aspergillus in culture-proven invasive infections in hematological malignancies and recipients of stem cell transplants. In mucormycosis, Rhizopus species (47%) account for the majority of isolates followed by mucor, cunninghamella, ...
A trial design that generates only ''positive'' results
Jul 01, 2008; Ernst, E; Lee, M ... Randomized clinical trials (RCTs) are designed to minimize bias in comparative tests of therapeutic effectiveness. However, they are not always free of bias. In recent years, we have seen a plethora of RCTs adopting a design where patients are randomized to receive either usual care (the control ...
Promotional literature: How do we critically appraise?
Jul 01, 2008; Shetty, V; Karve, A ... One hundred and twenty-two new and generic drugs were approved by the FDA in October 2007. [1] The number of drugs entering the market is growing at an alarming rate. In short there is an information explosion. Thus it is almost impossible for a busy medical professional to study and compile the ...
Story of heparin recall: What India can do?
Jul 01, 2008; Harugeri, A; Parthasarathi, G; Ramesh, M; Sharma, J; Devi, D Padmini ... Heparin is an anticoagulant that is commonly administered intravenously or subcutaneously and primarily used in the treatment or prevention of other serious medical conditions, including deep venous thrombosis and pulmonary emboli. [1] Heparin is available in different strengths and is widely ...
A young lady with hypotension and engorged neck veins
Jul 01, 2008; Aggarwal, A; Sharma, V; Agarwal, M; Giri, S ... A 25-year-old woman presented to us with history of breathlessness. The lady had noticed progressively increasing fatigue in the past six months and had a sense of generalized weakness. Over the past week or so she had been unable to do even routine chores at home and had been breathless since ...
Electroconvulsive therapy and electrocardiograph changes
Jul 01, 2008; Narasimhan, S ... A 70-year-old woman with a body mass index of 25 kg/m 2 and recalcitrant depression on a background of quiescent polycythemia rubra vera and carcinoma breast was scheduled for electroconvulsive therapy (ECT). Her current medications were aspirin 150 mg mane on alternative days, quetiapine 50 mg ...
Benign nevus inclusions in a node with primary squamous carcinoma of tongue
Jul 01, 2008; Goyal, M; Goliwale, F; Deodhar, K ... A 65-year-old female presented with an ulcerative lesion over the left lateral border of the tongue for six months which had increased in size gradually. There was a history of chewing betel nuts, pan masala and betel leaf. The biopsy of the lesion revealed squamous cell carcinoma, following ...
Needlestick injury to a patient
Jul 01, 2008; Onal, E; Tanriover, M; Guven, G ... A 49-year-old, diabetic woman was admitted to the wards to search for the etiology of proteinuria. She was diagnosed to have Type 2 diabetes 16 years ago and had been using insulin from that time. She had diabetic retinopathy and neuropathy. She described paraesthesia in the hands and feet ....
Gatifloxacin-induced rhabdomyolysis
Jul 01, 2008; George, P; Das, J; Pawar, B; Badyal, D ... Flouroquinolone antibiotics cause musculoskeletal adverse effects like myalgia, arthralgia, tendon disorders and rhabdomyolysis. [1] Ofloxacin and levofloxacin rarely cause rhabdomyolysis, [2] but gatifloxacin has not yet been reported to cause rhabdomyolysis. A 50-year-old male was ...
L-tryptophan and scleroderma: Significance of nutritional supplements containing L-tryptophan
Jul 01, 2008; Feroze, K; Venkitakrishnan, S; Manoj, J ... Pregnancy supplements containing amino-acid components like L-tryptophan have been banned in some countries, but continue to be available in India. We report a case of scleroderma-like syndrome possibly linked to L-tryptophan containing pregnancy supplements. A 28-year-old female ...
Symptomatic hypocalcemia following intravenous administration of zoledronic acid in a breast cancer patient
Jul 01, 2008; Mishra, A ... Bisphosphonates are increasingly being incorporated in the management of patients with breast cancer. [1] With wider adoption of bisphosphonates, the incidence of some rare complications like hypocalcaemia might go up, particularly in vitamin D deficient populations. Here we would like to share ...
Kayser-Fleischer ring
Jul 01, 2008; Suvarna, J ... Kayser-Fleischer ring (K-F ring), also referred to as Fleischer-Kayser ring or Fleischer-Strumpell ring was first described by the German ophthalmologists Bernhard Kayser (1902) and Bruno Fleischer (1903) independently in a patient who was then diagnosed to have multiple sclerosis. Fleischer in ...