Recently added articles from Mayo Clinic Proceedings:
Pseudomembranes on Colostomy
Mar 01, 2009; ... An 85-year-old male nursing home resident presented with confusion and lethargy of 2 days' duration. His medical history was remarkable for chronic renal insufficiency; prostate cancer, for which irradiation had been given; rectosigmoid resection with Hartman pouch secondary to bowel ...
Carotid Intima-Media Thickness: Can It Close the "Detection Gap" for Cardiovascular Risk?
Mar 01, 2009; ... Given the high morbidity and mortality and the large societal burden imposed by cardiovascular (CV) disease, there have been many strong interdisciplinary efforts to identify at-risk patients during the past decades. The Framingharn study and other population-based studies of CV risk, outcomes, ...
A Cross-sectional Study of Intima-Media Thickness, Ethnicity, Metabolic Syndrome, and Cardiovascular Risk in 2268 Study Participants
Mar 01, 2009; ... OBJECTIVE: To describe the association between intima-media thickness (IMT) and metabolic syndrome (MetS) and to examine if the addition of IMT to a traditional MetS definition adds value to the assessment of predicted cardiovascular disease (CVD) risk in a large multiethnic ...
Carotid Intima-Media Thickness and Coronary Artery Calcium Score as Indications of Subclinical Atherosclerosis
Mar 01, 2009; ... OBJECTIVE: To determine the ability of carotid intima-media thickness (CIMT) and coronary artery calcium score (CACS) to detect subclinical atherosclerosis in a young to middle-aged, low-risk, primary-prevention population. PATIENTS AND METHODS: Patients aged 36 to 59 years who underwent ...
Benefits and Risks of Long-term Amiodarone Therapy for Persistent Atrial Fibrillation: A Meta-analysis
Mar 01, 2009; ... OBJECTIVE: To assess whether amiodarone, as part of a strategy to achieve sinus rhythm, is safe and effective compared with a placebo or rate control drug in patients with persistent atrial fibrillation (AF) of more than 30 days' duration. METHODS: Randomized controlled trials comparing ...
Patients' Attitudes and Preferences About Participation and Recruitment Strategies in Clinical Trials
Mar 01, 2009; ... OBJECTIVE: To assess attitudes of patients about participation in clinical trials. PATIENTS AND METHODS: This is a self-report survey of 400 patients who underwent general medical evaluations between September and November 2006 at a tertiary care academic medical center in Rochester, MN ....
A Systematic Review of Outcomes and Quality Measures in Adult Patients Cared for by Hospitalists vs Nonhospitalists
Mar 01, 2009; ... A systematic review of English-language literature was undertaken to answer the question, "Are there differences in cost or quality of Inpatient medical care provided to adults by hospitalists vs nonhospitalists?" A computerized search was performed, using hospitalist and either quality, ...
"I'm Going Home": Discharges Against Medical Advice
Mar 01, 2009; ... Discharge against medical advice (AMA), in which a patient chooses to leave the hospital before the treating physician recommends discharge, continues to be a common and vexing problem. This article reviews the prevalence, costs, predictors, and potential interventions for this clinical problem ....
Milk-Alkali Syndrome
Mar 01, 2009; ... Milk-alkali syndrome (MAS) consists of hypercalcemia, various degrees of renal failure, and metabolic alkalosis due to ingestion of large amounts of calcium and absorbable alkali. This syndrome was first identified after medical treatment of peptic ulcer disease with milk and alkali was widely ...
Mechanisms of Drug-Induced Allergy
Mar 01, 2009; ... We identified English-language publications on hypersensitivity reactions to xenobiotics through the PubMed database, using the search terms drug and/or xenoblotlc, hypersensitivity reaction, mechanism, and immune mediated. We analyzed articles pertaining to the mechanism and the role of T ...
Herpes Zoster (Shingles) and Postherpetic Neuralgia
Mar 01, 2009; ... Herpes zoster (HZ), commonly called shingles, is a distinctive syndrome caused by reactivation of varicella zoster virus (VZV). This reactivation occurs when Immunity to VZV declines because of aging or immunosuppression. Herpes zoster can occur at any age but most commonly affects the elderly ...
79-Year-Old Man With Fever, Malaise, and Jaundice
Mar 01, 2009; ... A 79-year-old man from western Wisconsin presented to an outside emergency department in July with a 4day history of fever and malaise. He denied chest pain, palpitations, shortness of breath, cough, constipation, diarrhea, and rashes. He had been experiencing nocturia, and his wife noted very ...
25-Year-Old Woman With New-Onset Seizures
Mar 01, 2009; ... A 25-year-old woman presented to the emergency department (ED) with a history of 2 seizures before presentation. According to the family, the first seizure occurred around 3 pm on the day of presentation. It was described by the paramedics and bystanders as a generalized tonic-clonic event ...
Ventricular Tachycardia and Sudden Cardiac Death
Mar 01, 2009; ... Ventricular tachycardia (VT), which most commonly occurs in patients with structural heart disease, can be associated with an Increased risk of sudden death. The most common cause of ventricular fibrillation is acute coronary Ischemia, whereas a myocardial scar from prior infarct is the most ...
Erectile Dysfunction and the "Window of Curability": A Harbinger of Cardiovascular Events
Feb 01, 2009; ... In their landmark 2005 report of more than 9400 men, Thompson et al1 posed the following questions: "With the high prevalence of erectile dysfunction in aging men, do pharmacologic, lifestyle, or behavioral interventions that are cardioprotective also reduce or delay onset of erectile ...
A Population-Based, Longitudinal Study of Erectile Dysfunction and Future Coronary Artery Disease
Feb 01, 2009; ... OBJECTIVE: To assess the association between erectile dysfunction (ED) and the long-term risk of coronary artery disease (CAD) and the role of age as a modifier of this association. PARTICIPANTS AND METHODS: From January 1, 1996, to December 31, 2005, we biennially screened a random ...
Bronchopulmonary Actinomycosis Associated With Hiatal Hernia
Feb 01, 2009; ... OBJECTIVES: To describe clinlcoradiologlc and histopathologic features of bronchopulmonary actinomycosis and to determine whether hiatal hernia (HH) is a potential predisposing factor for bronchopulmonary actinomycosis. PATIENTS AND METHODS: We reviewed the medical charts of 10 patients ...
Pleural Fluid Characteristics of Chylothorax
Feb 01, 2009; ... OBJECTIVE: To determine the biochemical parameters of chylous pleural fluids and better inform current clinical practice in the diagnosis of chylothorax. PATIENTS AND METHODS: We retrospectively reviewed 74 patients with chylothorax (defined by the presence of chylomicrons) who underwent ...
Clinical and Genetic Description of a Family With a High Prevalence of Autosomal Dominant Restless Legs Syndrome
Feb 01, 2009; ... OBJECTIVE: To conduct clinical and molecular genetic analyses of the members of an extended family in Central Indiana with a high prevalence of restless legs syndrome (RLS). PARTICIPANTS AND METHODS: From February 1, 2006, through August 31, 2008, we collected data from members of this ...
Erectile Dysfunction and Cardiovascular Disease: Efficacy and Safety of Phosphodiesterase Type 5 Inhibitors in Men With Both Conditions
Feb 01, 2009; ... Risk factors for cardiovascular disease and erectile dysfunction (ED) are similar, as might be expected given their shared etiologlc and pathophysiologic origins. It is now generally accepted that most cases of ED result from a vascular disturbance of the endothelium. Recent epidemiological ...