Recently added articles from Mayo Clinic Proceedings:
Blue Esophagus
Oct 01, 2008; Marath, Biju; Abbasi, Jamil ... An 85-year-old female nursing home resident, with a known history of dementia, cerebrovascular disease, hypertension, and chronic dysuria, presented with a day's history of pain on the right side of the chest, nausea, and vomiting of blue material. When results from electrocardiography and ...
Mutations in a Molecule: The Virtues of Antagonism
Oct 01, 2008; Kharasch, Evan D ... Drug development has evolved through eras of natural product use (willow bark, which contains aspirin), serendipitous discovery (penicillin from bread mold), more rational drug design that involves the testing of diverse synthetic analogues and structural refinement after identification of ...
Survival Trends in Patients With Gastric and Esophageal Adenocarcinomas: A Population-Based Study
Oct 01, 2008; Crane, Sarah J; Locke, G Richard III; Harmsen, William S; Zinsmeister, Alan R; Romero, Yvonne; Talley, Nicholas J ... OBJECTIVE: To use a population-based approach to describe survival trends in patients diagnosed as having gastric or esophageal adenocarcinoma. PATIENTS AND METHODS: A population-based complete chart review of all inpatient and outpatient records, using the resources of the Rochester ...
Mortality Associated With Nephropathy After Radiographic Contrast Exposure
Oct 01, 2008; From, Aaron M; Bartholmai, Brian J; Williams, Amy W; Cha, Stephen S; McDonald, Furman S ... OBJECTIVE: To define outcomes from contrast-induced nephropathy (CIN) after both intra-arterial and intravenous administration of contrast medium. PATIENTS AND METHODS: We performed a retrospective case-matched cohort study at Mayo Clinic's site in Rochester, MN, from April 1, 2004, to ...
Effect of Baseline Glomerular Filtration Rate on Survival in Patients Undergoing Partial or Radical Nephrectomy for Renal Cortical Tumors
Oct 01, 2008; Pettus, Joseph A; Jang, Thomas L; Thompson, Robert H; Yossepowitch, Ofer; Kagiwada, Meagan; Russo, Paul ... OBJECTIVE: To evaluate the effect of baseline renal function and comorbldlty Index on survival In patients with renal tumors. PATIENTS AND METHODS: We retrieved demographic, clinicopathologic, body mass index (BMI), and comorbidity data (assessed by Charlson-Romano index and ...
Increased Left Atrial Volume Index: Potent Biomarker for First-Ever Ischemic Stroke
Oct 01, 2008; Fatema, Kaniz; Bailey, Kent R; Petty, George W; Meissner, Irene; Osranek, Martin; Alsaileek, Ahmed A; Khandheria, Bijoy K; Tsang, Teresa S; Seward, James B ... OBJECTIVE: To establish the incidence and correlation of increased left atrial volume index (LAVI) in patients with first-ever ischemic stroke. PARTICIPANTS AND METHODS: Using our institution's epidemic-logical database, we defined a cohort of 432 patients (cases) who underwent ...
Development of Peripheral Opioid Antagonists: New Insights Into Opioid Effects
Oct 01, 2008; Moss, Jonathan; Rosow, Carl E ... The recent approval by the US Food and Drag Administration of 2 medications-methylnaltrexone and alvimopan-introduces a new class of therapeutic entitles to clinicians. These peripherally acting µ-opioid receptor antagonists selectively reverse opioid actions mediated by receptors outside the ...
Autologous Stem Cell Transplant in 716 Patients With Multiple Myeloma: Low Treatment-Related Mortality, Feasibility of Outpatient Transplant, and Effect of a Multidisciplinary Quality Initiative
Oct 01, 2008; Gertz, Morie A; Ansell, Stephen M; Dingli, David; Dispenzieri, Angela; Buadi, Francis K; Elliott, Michelle A; Gastineau, Dennis A; Hayman, Suzanne R; Hogan, William J; Inwards, David J; Johnston, Patrick B; Kumar, Shaji; Lacy, Martha Q; Leung, Nelson ... We report on the feasibility of outpatient transplant in 716 patients undergoing autologous stem cell transplant for multiple myeloma at Mayo Clinic's site in Rochester, MN, from January 1, 2000, through October 31, 2007. We also report on the development and effect of a multidisciplinary ...
Physicians' Preferences and Attitudes About End-of-Life Care in Patients With an Implantable Cardioverter-Defibrillator
Oct 01, 2008; Sherazi, Saadia; Daubert, James P; Block, Robert C; Jeevanantham, Vinodh; Abdel-Gadir, Khalid; DiSalle, Michael R; Haley, James M; Shah, Abrar H ... Clinical guidance is deficient regarding deactivation of implantable cardioverter-defibrillators (ICDs) in patients with terminal illnesses. We hypothesized that many physicians are apprehensive about discussing ICD deactivation with their dying patients. Thus, we conducted an anonymous survey ...
Treatment of Myeloma: Cure vs Control
Oct 01, 2008; Rajkumar, S Vincent ... Although not often openly acknowledged, "cure vs control" is the dominant philosophical difference behind many of the strategies, trials, and debates related to the management of myeloma. Should we treat patients with myeloma with multidrug, multitransplant combinations with the goal of ...
Frailty and Its Potential Relevance to Cardiovascular Care
Oct 01, 2008; Singh, Mandeep; Alexander, Karen; Roger, Véronique L; Rihal, Charanjit S; Whitson, Heather E; Lerman, Amir; Jahangir, Arshad; Nair, K Sreekumaran ... Frailty Is characterized by vulnerability to acute Stressors and Is a consequence of decline In overall function and physiologic reserves. An estimated 7% of the US population older than 65 years and 30% of octogenarians are frail. The domains to define frailty Include mobility, strength, ...
Amebiasis
Oct 01, 2008; Pritt, Bobbi S; Clark, C Graham ... On completion of this article, you should be able to: (1) request the appropriate tests for differentiating the morphologically identical Entamoeba species E histolytica, E dispar, and E moshkovskii on the basis of initial laboratory reports; (2) recognize symptoms and complications of invasive ...
75-Year-Old Man With Abdominal Pain and Weight Loss
Oct 01, 2008; Leise, Michael D; Jacobson, Kurt M; Chari, Suresh T ... A 75-year-old man presented to the outpatient clinic with a 9-kg weight loss during the preceding several months and mild midepigastric pain radiating to the back. His medical history was unremarkable. He was a former smoker and lifelong nondrinker. Review of systems was notable only for a ...
The Massa or Rochester Plastic Needle
Oct 01, 2008; Southorn, Peter A; Narr, Bradly J ... In 1950, a short article in the Proceedings of the Staff Meetings of the Mayo Clinic provided the first description of the modern intravenous catheter.1 Written by Mayo Clinic anesthesiology resident David J. Massa (1923-1990) (Figure 1, left) and associates, this article represents a milestone ...
Introduction to Symposium on Cardiovascular Diseases
Oct 01, 2008; Gerber, Thomas C; Asirvatham, Samuel J; Lavie, Carl J; Oh, Jae K ... During the next 18 months, Mayo Clinic Proceedings will present a series of articles that address the contemporary evaluation and management of patients with various cardiovascular (CV) diseases. Signs and symptoms suggestive of incident CV disease, such as chest pain, dyspnea, peripheral edema, ...
Low-Dose Statin Concentration in Red Yeast Rice: A Confounding Effect on Outcome?/In reply
Oct 01, 2008; Yovchevski, Plamen Hristov; Doncheva, Nadezhda Ivanova; Becker, David ... To the Editor: The recent article by Becker et al1 reporting results from the Simvastatin vs Therapeutic Lifestyle Changes and Supplements: Randomized Primary Prevention Trial shows that patients with hyperlipidemia could benefit from lifestyle changes combined with ingestion of red yeast rice ...
Contemporary Pacemakers: What the Primary Care Physician Needs to Know
Oct 01, 2008; Kaszala, Karoly; Huizar, Jose F; Ellenbogen, Kenneth A ... Pacemaker therapy is most commonly initiated because of symptomatic bradycardia, usually resulting from sinus node disease. Randomized multicenter trials assessing the relative benefits of different pacing modes have made possible an evidence-based approach to the treatment of bradyarrhythmias ....
Urinary Tobacco Alkaloid Measurement in Patients Having Thromboangiitis Obliterans/In reply
Oct 01, 2008; Hurt, Richard D; Hays, J Taylor; Geske, Jeffrey B; Calvin, Andrew D; McDonald, Furman S ... To the Editor. The recent Residents' Clinic by Geske et al1 points out the difficulties of diagnosing thromboangiitis obliterans (TAO or Buerger disease) when the patient admits past smoking but denies current tobacco use.1 Denial and rationalization are common features of tobacco dependence, ...
Hysteroscopic Sterilization in Women With Pulmonary Vascular Disease/In reply
Oct 01, 2008; Hemnes, Anna R; Robbins, Ivan M; Famuyide, Abimbola O; Hopkins, Matthew R; El-Nashar, Sherif A; Creedon, Douglas J; Vasdev, Gurinder M; Driscoll, David J; Connolly, Heidi M; Warnes, Carole A ... To the Editor. We read with interest the recent article by Famuyide et al1 on hysteroscopic sterilization in women with severe cardiac disease. We were particularly interested in the inclusion of patients with pulmonary vascular disease, whom the authors rightly describe as having increased risk ...
CORRECTIONS
Oct 01, 2008; Anonymous ... Incorrect numbers: In the article by Smith et al entitled "Chronic Care Model and Shared Care in Diabetes: Randomized Trial of an Electronic Decision Support System," published in the July issue of Mayo Clinic Proceedings (Mayo Clin Proc. 2008;83(7):747-757), 1 number and its corresponding ...