Recently added articles from Neurology India:
Anticytotics - Radiopalliation/chemopalliation and neuraxial neoplasms
Apr 01, 2008; Kothari, Manu; Goel, Atul ... The Bard of Stratford-on-Avon, has aphorized in Romeo and Juliet (2,ii,43) that "a rose, by any other name, would smell as sweet". Given his versatility, he would have loved to complete the story by adding that "a thorn, by any other name, would prick as deep". To euphemistically elevate ...
rAAV vector-mediated gene therapy for experimental ischemic stroke
Apr 01, 2008; Li, Zhao-Jian; Wang, Ren-zhi ... Stroke is the leading cause of disability and the third leading cause of death in major industrialized countries and about 85% strokes are ischemic. [1] However, an effective treatment for this condition has not been established apart from the thrombolytic recombinant tissue plasminogen ...
Clinical speech impairment in Parkinson's disease, progressive supranuclear palsy, and multiple system atrophy
Apr 01, 2008; Sachin, S; Shukla, G; Goyal, V; Singh, S; Aggarwal, Vijay; Behari, M ... Speech impairment in Parkinsonian syndromes causes considerable impact on patients' social and emotional well-being. [1] Speech disorder seen in Parkinson's disease (PD) is hypokinetic dysarthria characterized by abnormalities like inability to maintain loudness, monotonous and harsh voice, ...
Hemispherotomy for intractable epilepsy
Apr 01, 2008; Chandra, Poodipedi; Padma, Vasantha; Shailesh, Gaikwad; Chandreshekar, Bal; Sarkar, Chitra; Tripathi, Manjari ... Functional hemispherotomy is indicated in patients with intractable epilepsy with a diffuse unicerebral pathology. Among the various choices available for epilepsy surgery, this procedure provides the highest rate of seizure control (average 77-80%, Class I Engel) when performed in properly ...
Fiber dissection of the visual pathways: Analysis of the relationship of optic radiations to lateral ventricle: A cadaveric study
Apr 01, 2008; Pujari, Vikrant; Jimbo, Hiryuki; Dange, Nitin; Shah, Abhidha; Singh, Sukhdeep; Goel, Atul ... Introduction In temporal lobe region surgery, for tumors and epilepsy, the exact anatomical relationship of the optic tract fibers to temporal horn are inadequately visualized on conventional cadaveric brain dissection. Fiber dissection of the brain delineates the anatomical details of ...
Surgical outcome of cortical dysplasias presenting with chronic intractable epilepsy: A 10-year experience
Apr 01, 2008; Tripathi, Manjari; Singh, Mahendra; Padma, M; Gaikwad, Shailesh; Bal, C; Tripathi, Madhavi; Sarkar, C; Gupta, Aditya; Shukla, Garima; Singh, V; Jain, Satish; Sharma, Bhawani; Chandra, P ... Cortical dysplasia (CD) is an uncommon pathology causing intractable epilepsy. Over the recent years, more cases are being recognized with improvement in diagnostics and imaging. Since the inception of the epilepsy surgery program in 1995, we have operated upon more than 400 cases of intractable ...
Atlantoaxial joint distraction as a treatment for basilar invagination: A report of an experience with 11 cases
Apr 01, 2008; Goel, Atul; Shah, Abhidha ... A variety of methods have been described to treat basilar invagination. We had classified basilar invagination into two groups. [1],[2] In Group A basilar invagination, there was a "fixed" atlantoaxial dislocation and the tip of the odontoid process "invaginated" into the foramen magnum [3] and ...
Sleep seizures versus wake seizures: A comparative hospital study on clinical, electroencephalographic and radiological profile
Apr 01, 2008; Goel, Deepak; Mittal, Manish; Bansal, K; Srivastav, R; Singhal, A ... The International League Against Epilepsy (ILAE) defined sleep seizures (SS) as "seizures occurring exclusively or predominantly (more than 90%) during sleep". [1] Proportion of patients with SS ranges from 7.5 to 45% (average 12%) in different studies. [2],[3] Sleep has an important ...
Serotonin transporter gene polymorphisms in patients with chronic tension-type headache: A preliminary study
Apr 01, 2008; Akcali, Aylin; Tataroglu, Cengiz; Erdal, Emin; Aydin, Neriman; Pehlivan, Sacide ... Primary headaches constitute a major health problem and this is why there has been an increasing interest in the genetic associations of these widespread disorders within the last couple of years. Chronic tension-type headache (CTTH) occurs on at least 15 days in a month for up to three months ...
Utility of the Malayalam translation of the 7- minute screen for Alzheimer's disease risk in an Indian community
Apr 01, 2008; de Jager, Celeste; Thambisetty, Madhav; Praveen, K; Sheeba, P; Ajini, K; Sajeev, A; Smitha, K; Rahmathulla, L; Ramakrishna, T; David, Smith ... Screening for Alzheimer's disease (AD) is not a routine diagnostic procedure for the elderly in India and it is likely that dementia is vastly under-diagnosed. Poor awareness of dementia in the community is a factor that influences the number of older people seeking medical attention. The World ...
Endovascular treatment of scalp cirsoid aneurysms
Apr 01, 2008; Gupta, A; Purkayastha, S; Bodhey, N; Kapilamoorthy, T; Krishnamoorthy, T; Kesavadas, C; Thomas, B ... Arteriovenous fistulae were first described by Hunter in 1757. [1] The term cirsoid aneurysm was applied to vascular malformations of the scalp in 1833 by Brecht. [1] The malformation is drained by enlarged, tortuous veins, which may, in parts, show variceal dilatation. Various names have been ...
Solitary metastasis of renal cell carcinoma to the third ventricular choroid plexus with rapid clinical manifestation by intratumoral hemorrhage
Apr 01, 2008; Tomiyama, Arata; Nakayama, Haruo; Aoki, Kazuya; Ueda, Morikazu ... Although the choroid plexus receives an abundant supply of blood, metastasis of renal cell carcinoma (RCC) to the choroid plexus is the least common form of brain metastasis. [1],[2],[3] In particular, a metastasis to the third ventricle has never been reported. We describe the first case of a ...
Reversible white matter abnormalities in a patient with migraine
Apr 01, 2008; Agarwal, Shalini; Magu, Sarta; Kamal, Kirti ... Migraine is a very common debilitating disorder. Patients with migraine are at increased risk of white matter hyperintensities detected on magnetic resonance imaging (MRI). Also, migraine has been implicated as an independent risk factor in stroke with the incidence of active migraine (both with ...
Aspergillus sellar abscess: Case report and review of the literature
Apr 01, 2008; Hao, Li; Jing, Chen; Bowen, Cai; Min, He; Chao, You ... Aspergillus sellar abscess, which is a rare form of central nervous system (CNS) fungal infections, is usually misdiagnosed because its presentation is similar to that of a pituitary adenoma. Although it is benign and curable, a delay in the diagnosis and treatment may lead to significant ...
Toxoplasma granuloma of brainstem: A rare case
Apr 01, 2008; Gupta, Anurag; Raja, A; Mahadevan, A; Shankar, S ... Toxoplasmosis presenting as intracranial space-occupying lesions in immunocompromised patients is a common occurrence, being one of the most common opportunistic lesions in patients with the Acquired Immuno Deficiency Syndrome (AIDS). [1],[2] In immunocompetent patients it has been reported to ...
Insulinoma: Reversal of brain magnetic resonance imaging changes following resection
Apr 01, 2008; Pakhetra, Rajiv; Priya, Gagan; Jyotsna, Viveka; Seith, Ashu; Ammini, Ariachery ... Insulinoma can present with disorders of cognition, consciousness, epilepsy, psychosis, dementia and neuropathy. [1],[2],[3],[4],[5] Misdiagnosis and delay in treatment are common and may lead to prolonged hypoglycemia with permanent neurological deficit or fatal coma. [3] Diagnosis ...
Acute subdural effusion in vasculitis
Apr 01, 2008; Raghavendra, Seetharam; Kamath, Vidya Madavana; Sarada, C; Radhakrishnan, Ashalatha; Kesavadas, Chandrasekharan; Krishnamoorthy, Thamburaj ... Vasculitis affecting the central nervous system (CNS) very rarely presents as acute or chronic meningoencephalitis. [1] Very few cases of subdural effusion in vasculitis are reported in the literature. [2],[3],[4],[5] We report here a case of vasculitis affecting the CNS manifesting as acute ...
Miller-Fisher syndrome associated with chronic lymphocytic leukemia
Apr 01, 2008; Aki, Zeynep; Aksoy, Ozlem; Sucak, Gulsan; Kuruoglu, Reha; Yagci, Munci ... Chronic lymphocytic leukemia (CLL) is a frequent hematological malignancy, with meningeal or peripheral nerve infiltrations being the most commonly encountered neurological complications, albeit rare. [1] Miller-Fisher syndrome (MFS) is an immune-mediated inflammatory neuropathy, characterized ...
Uncommon neurological manifestations of hemolytic anemia: A report of two cases
Apr 01, 2008; Ramu, Chitela; Raju, Garuda; Rao, Kolli; Venkateswarlu, Kolichana ... Sickle cell disease (SCD), the homozygous state for sickle cell gene (SS Hb pattern) is an important risk factor in the development of stroke and most strokes occur in subjects under the age of 15 years. By contrast, sickle cell trait (SCT-AS Hb pattern) is considered to be a benign condition ....
Retinal detachment presumably associated with topiramate
Apr 01, 2008; Dey, K; Das, S; Mishra, A; Guha, G ... Sir, Topiramate is a sulfamate-substituted monosaccharide. Its usefulness in migraine prevention was shown in several large randomized controlled trials. [3],[4],[5] In this article, we describe two patients who took topiramate as a migraine prophylaxis and subsequently developed retinal ...