Obesity & Diabetes Week back issues from March 2009:
Stem cell research uncovers mechanism for type 2 diabetes.
Mar 02, 2009 ... Taking clues from their stem cell research, investigators at the University of California San Diego (UC San Diego) and Burnham Institute for Medical Research (Burnham) have discovered that a signaling pathway involved in normal pancreatic development is also associated with type 2 ...
It's no fish tale: Omega-3 fatty acids prevent medical complications of obesity.
Mar 02, 2009 ... According to a recent study published online in The FASEB Journal (http://www.fasebj.org), diets rich in omega-3 fatty acids protect the liver from damage caused by obesity and the insulin resistance it provokes. This research should give doctors and nutritionists valuable information when ...
Gladstone scientists reveal that fat synthesizing enzyme is key to healthy skin and hair.
Mar 02, 2009 ... Scientists at the Gladstone Institutes of Cardiovascular Disease (GICD) have found that an enzyme associated with the synthesis of fat in the body is also an element in healthy skin and hair. The enzyme is acyl CoA:diacylglycerol acyltransferase 1 or DGAT1. Mice that lack DGAT1 have many ...
Research on cardiovascular disease detailed by C.R. Zamora and co-authors.
Mar 02, 2009 ... "Microalbuminuria (30-300mg of albumin/24 h) is a well-known independent risk factor for kidney and cardiovascular disease and of mortality in diabetic, hypertensive and in the general population. However, recent studies indicate that increased risk is observed at levels of albuminuria ...
Reports on diabetes findings from Murdoch University provide new insights.
Mar 02, 2009 ... According to recent research from Australia, "The absence or 'missingness' of single nucleotide polymorphism (SNP) assay values because of genotype or related factors of interest may bias association and other studies. Missingness was determined for the Type 1 Diabetes Genetics Consortium ...
Studies in the area of diabetes reported from Wake Forest University.(Report)
Mar 02, 2009 ... "The aim of this study was to perform quality control (QC) and initial family-based association analyses on the major histocompatibility complex (MHC) single nucleotide polymorphism (SNP) and microsatellite marker data for the MHC Fine Mapping Workshop through the Type 1 Diabetes Genetics ...
Findings from G. Morahan and co-authors provide new insights into diabetes risk.
Mar 02, 2009 ... According to recent research published in the journal Diabetes Obesity & Metabolism, "Type 1 diabetes susceptibility is influenced by a number of genes, of which those with the strongest effects map to the human leucocyte antigen (HLA) complex. Evidence for linkage of non-HLA genes in ...
Research from Polytechnic University provide new insights into life sciences.
Mar 02, 2009 ... According to recent research from Ancona, Italy, "The aim of this prospective observational study was to assess the 3-year clinical outcome of distal realignment and membrane-seeded autologous chondrocyte implantation (MACI(A (R))) in selected patients with patellofemoral malalignment and ...
Studies from Oslo University College describe new findings in life sciences.
Mar 02, 2009 ... According to a study from Oslo, Norway, "GJOVAAG, T. F., and H. A. DAHL. Effect of Training with Different Mechanical Loadings oil MyHC and GLUT4 Changes. Med. Sci. Sports Exerc., Vol. 41, No. 1, pp. 129-136, 2009." "There is an inverse relationship between insulin sensitivity ...
Studies in the area of life sciences reported from University of East Anglia.(Report)
Mar 02, 2009 ... According to recent research from Norwich, the United Kingdom, "Circulating adiponectin is emerging as an important link between obesity, type 2 diabetes, and cardiovascular disease (CVD). However, the spectrum of lifestyle factors that modulate the adiponectin concentration remains to be ...
Reports summarize metabolism research from Stanford University, Medical Department.
Mar 02, 2009 ... According to a study from the United States, "Sleep disturbances are associated with hormonal imbalances and may result in metabolic disorders including obesity and diabetes." "Therefore, circuits controlling both sleep and metabolism are likely to play a role in these ...
New findings reported from Washington University describe advances in obesity.(Report)
Mar 02, 2009 ... According to recent research from the United States, "It has been hypothesized that excessive fatty acid availability contributes to steatosis and the metabolic abnormalities associated with nonalcoholic fatty liver disease (NAFLD). The purpose of this study was to evaluate whether adipose ...
New obesity research has been reported by scientists at Medical College.
Mar 02, 2009 ... According to recent research from Harbin, People's Republic of China, " We examined the potential impact of the 5-hydroxytryptamine 2A receptor (5-HT2AR) c.1438A >G promoter polymorphism on obesity and estimates of insulin, glucose as well as lipid metabolism. The genotypes and allelic ...
Research from Shiga University provides new data about obesity.
Mar 02, 2009 ... According to a study from Japan, "Deji N, Kume S, Araki S, Soumura M, Sugimoto T, Isshiki K, Chin-Kanasaki M, Sakaguchi M, Koya D, Haneda M, Kashiwagi A, Uzu T. Structural and functional changes in the kidneys of high-fat diet-induced obese mice. Am J Physiol Renal Physiol 296: F118-F126, ...
Research from Texas A&M University provide new insights into obesity.(Report)
Mar 02, 2009 ... "Previous studies showed that dietary L-arginine supplementation decreased white fat mass in genetically obese rats. This study tested the effectiveness Of L-arginine in diet-induced obesity," investigators in the United States report (see also Obesity). "Male Sprague-Dawley ...
Scientists at National Chung-Hsing University release new data on obesity.(Report)
Mar 02, 2009 ... "Dietary fat is one of the most important environmental factors associated with the incidence of cardiovascular diseases. In this study, the antiobesity effects of rutin (R) and o-coumaric acid (oCA) were investigated," investigators in Taichung, Taiwan report (see also Obesity). ...
Data on obesity and diabetes detailed by A.C.D. Goncalves and co-authors.
Mar 02, 2009 ... "Leptin receptor-deficient db/db mice develop human type 2 diabetes mellitus, hypertension, and obesity with disrupted circadian blood pressure (BP) rhythm. Whether leptin is the sole mechanism mediating autonomic imbalance and hypertension is unclear," researchers in Berlin, Germany ...
Data on obesity and diabetes discussed by G. Thorleifsson and colleagues.
Mar 02, 2009 ... According to a study from Reykjavik, Iceland, "Obesity results from the interaction of genetic and environmental factors. To search for sequence variants that affect variation in two common measures of obesity, weight and body mass index (BMI), both of which are highly heritable, we ...
New obesity and diabetes data have been reported by A. Onat and co-authors.
Mar 02, 2009 ... "Lifestyle and metabolic determinants of incident hypertension in a population with a high prevalence of metabolic syndrome (MetS) need to be further assessed. A representative sample of middle-aged and elderly Turkish adults was prospectively evaluated over a mean 7.4 years, after ...
New obesity and diabetes research from I. Miwako et al outlined.(Report)
Mar 02, 2009 ... According to a study from Tamagawa, Japan, "Synthetic retinoid Am80 is a potent modulator of the immune system. Am80 is effective in various experimentally induced autoimmune disorders." "The purpose of this study is to confirm its effect on non-obese diabetic (NOD) mice, which ...
New obesity and diabetes study findings have been reported by T. Lajunen and co-researchers.
Mar 02, 2009 ... "Seropositivity for Chlamydia pneumoniae has been associated with an elevated body mass index (BMI). Our aim was to study if serum chlamydial lipopolysaccharide (cLPS), C. pneumoniae antibodies and high-sensitivity C-reactive protein (hsCRP) levels are associated with BMI Patients and ...
New obesity and diabetes study findings recently were published by researchers at Kurume University, Medical Department.
Mar 02, 2009 ... "Emerging evidence indicates an association between sympathetic activation and metabolic syndrome. However, sympathetic activation in metabolic syndrome may be a cause, consequence, or just epiphenomenon," scientists writing in the American Journal of Hypertension report (see also Obesity ...
New research on obesity and diabetes from University of Ancona summarized.
Mar 02, 2009 ... According to a study from Ancona, Italy, "The mammalian adipose organ is composed of subcutaneous and visceral depots containing white and brown adipocytes. Cold acclimatisation induces an increase in the brown component without affecting the overall number of adipocytes; this form of ...
Reports from M. Luqueramirez and colleagues advance knowledge in obesity and diabetes.
Mar 02, 2009 ... According to recent research from Madrid, Spain, "Increasing evidence suggests that adipocyte function is altered in the polycystic ovary syndrome (PCOS) as a result of androgen excess, providing an explanation for its frequent association with abdominal adiposity and insulin resistance ....
Research by G.W. Wong and colleagues in obesity and diabetes provides new insights.
Mar 02, 2009 ... According to recent research from the United States, "Adiponectin is a major insulin-sensitizing, multimeric hormone derived from adipose tissue that acts on muscle and liver to regulate whole-body glucose and lipid metabolism. Here, we describe a novel and highly conserved paralog of ...
Research from M.V.D.D. Martins and co-researchers provides new data on obesity and diabetes.
Mar 02, 2009 ... "Type 2 diabetes is an epidemic and insulin resistance is the central etiology of this disease. Obesity increases insulin resistance and glucose intolerance and also exacerbates metabolic abnormalities present in type 2 diabetes," scientists in Brazil report (see also Obesity and ...
Research from University of Kentucky has provided new data on obesity and diabetes.(Report)
Mar 02, 2009 ... According to recent research from the United States, "Mild obesity may have a protective effect against some diseases, termed an ''obesity paradox.'' This study examined the effect of body mass index (Kg/m(2) BMI) on surgical 30-day morbidity and mortality in patients undergoing vascular ...
Researchers' work from Karolinska University focuses on obesity and diabetes.
Mar 02, 2009 ... According to a study from Stockholm, Sweden, "Bioelectrical impedance (BIA) is quick, easy, and safe when quantifying fat and lean tissue. New BIA models (Tanita BC-418 MA, abbreviated BIA 8) can perform segmental body composition analysis, e. g., estimate % trunkal fatness (% TF)." ...
Studies conducted at F. Soriguer et al on obesity and diabetes recently published.
Mar 02, 2009 ... According to a study from Malaga, Spain, "Recent studies suggest that measuring the free-fatty acids (FFA) during an intravenous glucose tolerance test (IVGTT) may provide information about the metabolic associations between serum FFA and carbohydrate and insulin metabolism. We evaluated ...
Studies from H. Kahles et al provide new data on obesity and diabetes.
Mar 02, 2009 ... According to recent research from Frankfurt, Germany, "The Major Histocompatibility Complex (MHC) region on chromosome 6p21 (IDDM1) contributes about half of the familial clustering of type 1 diabetes (T1D). Several studies have revealed that highly polymorphic genes within the MHC may ...
Studies from Uppsala University in the area of obesity and diabetes described.
Mar 02, 2009 ... "Serotonin 2C and 2A receptor (5-HT2C and 5-HT2A) antagonisms are hypothesized to play a role in the metabolic adverse effects induced by olanzapine and clozapine, Associations between polymorphisms in 5-HT2C, and 5-HT2A receptor coding genes, HTR2C and HTR2A. with antipsychotic-induced ...
Study results from University of Pittsburgh in the area of obesity and diabetes published.(Report)
Mar 02, 2009 ... "Abnormal body mass index has been targeted as a predictor of complications after major surgery. The aim of this study was to review the impact of obesity on perioperative outcomes after minimally invasive esophagectomy," scientists in the United States report (see also Obesity and ...
Investigators at University of Colorado target type 1 diabetes.(Report)
Mar 02, 2009 ... "The goal of this study was to develop and implement methodology that would aid in the analysis of extended high-density single nucleotide polymorphism (SNP) major histocompatibility complex (MHC) haplotypes combined with human leucocyte antigen (HLA) alleles in relation to type 1 diabetes ...
New type 1 diabetes findings from C. Brorsson and co-researchers published.
Mar 02, 2009 ... "To develop novel methods for identifying new genes that contribute to the risk of developing type 1 diabetes within the Major Histocompatibility Complex (MHC) region on chromosome 6, independently of the known linkage disequilibrium (LD) between human leucocyte antigen (HLA)-DRB1, -DQA1, ...
New type 1 diabetes study results from St. Thomas' Hospital described.(Report)
Mar 02, 2009 ... According to a study from London, the United Kingdom, "Several studies have indicated that genes in the human leucocyte antigen (HLA) region additional to the HLA class II DRB1-DQB1 contribute to type 1 diabetes (T1D) susceptibility. The aim of this study was to assess if markers in the ...
Reports outline type 1 diabetes study results from Rockefeller University.
Mar 02, 2009 ... According to a study from the United States, "The human Major Histocompatibility Complex (MHC) is a highly polymorphic genomic region occupying approximately 4 Mb on chromosome 6p21.3. The relationship between human MHC and type 1 diabetes (T1D) has been previously investigated." ...
Research from University of Cambridge yields new findings on type 1 diabetes.
Mar 02, 2009 ... "Until recently, human leucocyte antigen (HLA) class II-independent associations with type 1 diabetes (T1D) in the Major Histocompatibility Complex (MHC) region were not adequately characterized owing to insufficient map coverage, inadequate statistical approaches and strong linkage ...
Scientists at University of California describe research in type 1 diabetes.
Mar 02, 2009 ... According to a study from the United States, "Type 1 diabetes (T1D) is a complex trait for which variation in the classical human leucocyte antigen (HLA) loci within the Major Histocompatibility Complex (MHC) significantly influences disease risk. To date, HLA class II DR-DQ genes confer ...
Studies from K. Badenhoop and co-authors have provided new information about type 1 diabetes.
Mar 02, 2009 ... "The region on chromosome 6p21 (IDDM1) confers the largest part of genetic susceptibility to type 1 diabetes (T1D) with particular human leucocyte antigen (HLA) alleles predisposing and others protecting from it. As T1D is primarily a ''sporadic'' disease, the pathophysiology must involve ...
New findings from Massachusetts General Hospital describe advances in weight loss.(Report)
Mar 02, 2009 ... "Despite its overall excellent outcomes, weight loss after Roux-en-Y gastric bypass (RYGB) is highly variable. We conducted this study to identify clinical predictors of weight loss after RYGB," researchers in the United States report (see also Weight Loss). "We reviewed charts ...
New insulin resistance risk factors study results reported from A. Misra et al.
Mar 02, 2009 ... Scientists discuss in 'South Asian diets and insulin resistance' new findings in insulin resistance. According to recent research from New Delhi, India, "A role of dietary nutrients in relation to insulin resistance has been suggested but conclusive evidence in human beings is lacking ....
New data from University of Chile illuminate research in obesity and diabetes in children.
Mar 02, 2009 ... Researchers detail in 'Insulin resistance markers in children,' new data in obesity and diabetes. "The prevalence of obesity among children and adolescents is progressively increasing around the world. One of the important consequences of obesity is the development of insulin resistance ...
Studies in the area of obesity and diabetes reported from Federal University, Department of Pediatrics.
Mar 02, 2009 ... Current study results from the report, 'Triglycerides and alanine aminotransferase as screening markers for suspected fatty liver disease in obese children and adolescents,' have been published. "Metabolic syndrome (MS) and fatty liver disease (FLD) are on the rise. The association between ...
Study data from University of California update understanding of obesity and diabetes vaccines.
Mar 02, 2009 ... Data detailed in 'Induction of autoimmune cholangitis in non-obese diabetic (NOD).1101 mice following a chemical xenobiotic immunization' have been presented. According to a study from the United States, "Our laboratory has suggested that loss of tolerance to pyruvate dehydrogenase ...
Report summarizes bariatrics study findings from D.S. Bond and co-researchers.(Report)
Mar 02, 2009 ... "The purpose of this study was to determine whether pre- to postoperative increases in physical activity (PA) are associated with weight loss and health-related quality of life (HRQoL) following bariatric surgery. Participants were 199 Roux-en-Y gastric bypass (RYGB) surgery patients," ...
Reports summarize bariatrics research from University of Nebraska.
Mar 02, 2009 ... "Vitamin D deficiency is common following bariatric surgery and is due to a combination of baseline deficiency and postoperative malabsorption. There are few prospective studies evaluating the appropriate dose of vitamin D to prevent and treat vitamin D deficiency following bariatric ...
Research from University of Padua has provided new data on bariatrics.(Report)
Mar 02, 2009 ... According to a study from Padua, Italy, "Small dense low-density lipoprotein (LDL) are atherogenic particles frequently observed in obese patients. Fatty acids modulate LDL." "Objective of this study was to determine the relations between plasma phospholipid fatty acid ...
Studies from E. Shang and co-researchers yield new data on bariatrics.(Report)
Mar 02, 2009 ... "The only effective treatment for patients with morbid obesity is surgery. Laparoscopic bariatric surgery has become quite popular in attempts to decrease the morbidity associated with laparotomy," scientists in Mannheim, Germany report (see also Bariatrics). "The aim of this ...
Study findings from T. Neitlich et al provide new insights into bariatrics.(Report)
Mar 02, 2009 ... "The purpose of this study was to compare computed tomography (CT) cholecystography and ultrasound for gallstone detection in preoperative bariatric surgery patients. The study included 16 asymptomatic prebariatric surgery patients," scientists writing in the journal Obesity Surgery report ...
Data on behavior discussed by researchers at University of California.
Mar 02, 2009 ... "Patterns of behavior exhibited by mice in their home cages reflect the function and interaction of numerous behavioral and physiological systems. Detailed assessment of these patterns thus has the potential to provide a powerful tool for understanding basic aspects of behavioral ...
Studies from Umea University have provided new data on breast cancer.(Clinical report)
Mar 02, 2009 ... "It is hypothesized that insulin resistance and related metabolic factors may influence breast cancer risk, however the epidemiological evidence remains inconclusive. We conducted a case-control study nested in a prospective cohort in Northern Sweden, to clarify the associations of body ...
New cancer research has been reported by scientists at University of Tokyo.
Mar 02, 2009 ... "Recent epidemiologic studies have shown a positive association between obesity and certain cancers. Our retrospective studies show that hypertriglyceridemia is an independent risk factor for the development of colonic adenoma and nodal metastasis in early gastric and esophageal cancer in ...
Research from Yokohama City University yields new findings on cancer.
Mar 02, 2009 ... According to a study from Kanagawa, Japan, "The association between obesity and the risk of colorectal cancer (CRC) cannot be easily evaluated because CRC itself is associated with a gradual loss of bodyweight. Aberrant crypt foci (ACF) can be classified as dysplastic ACF or non-dysplastic ...
New depression research has been reported by scientists at Deakin University.(Clinical report)
Mar 02, 2009 ... "This study examined the prospective associations of BMI, physical activity (PA), changes in BMI, and changes in PA, with depressive symptoms. Self-reported data on height, weight, PA, selected sociodemographic and health variables and depressive symptoms (CESD-10) were provided in 2000 ...
New findings from Creighton University in the area of depression published.
Mar 02, 2009 ... According to recent research from the United States, "Obesity is a health disparity related to environmental, social, and physical health issues, including ethnicity, education, and gender. The purpose of this study was to examine the relationship among obesity, age, education, and ...
Investigators at Technical University of Dresden zero in on diabetes.
Mar 02, 2009 ... "Type II diabetes mellitus is currently globally one of the fastest growing noncommunicable diseases, especially in developing countries. This investigation reports on a meta-analysis undertaken of the C-11377G locus within the adiponectin gene in a black South African, a Cuban Hispanic ...
Study data from National Institute on Drug Abuse update understanding of drug abuse.
Mar 02, 2009 ... "Obesity has been associated with a higher risk for impaired cognitive function, which most likely reflects associated medical complications (i.e., cerebrovascular pathology). However, there is also evidence that in healthy individuals excess weight may adversely affect cognition ...
Data on gastroenterology described by researchers at University of Texas.(Report)
Mar 02, 2009 ... According to recent research published in the journal Obesity Surgery, "Intestinal pacing (IP) has been previously shown to delay gastric emptying and reduce food intake in animals. The aims of this study were to investigate the effect and mechanism of IP on nutrient absorption in healthy ...
New gastroenterology study findings reported from M.R. Villalba and co-authors.
Mar 02, 2009 ... According to a study from the United States, "A 45-year-old female presented with an enterocutaneous fistula and intraabdominal abscesses weeks after undergoing an open roux-en-y gastric bypass 20 years after a previous bariatric procedure. Initial management consisted of exploration with ...
Studies from University of Texas have provided new information about gastroenterology.
Mar 02, 2009 ... According to a study from the United States, "We investigated the effects of cutaneous gastric electrical stimulation (CGES) on gastric myoelectrical activity, postprandial antral contractions and gastric tone in dogs. CGES was carried out via abdominal surface electrodes over the ...
Study results from Harvard University, Medical Department update understanding of headache and migraine.
Mar 02, 2009 ... "We evaluated the association of body mass index (BMI) with migraine and migraine specifics in a cross-sectional study of 63 467 women aged >= 45 years, of whom 12 613 (19.9%) reported any history of migraine and 9195 had active migraine. Compared with women without migraine and a BMI = 35 ...
New findings from University of London in the area of hormones described.
Mar 02, 2009 ... According to recent research published in the Journal of Physiology - London, "The last decade has witnessed a marked increase in our understanding of the importance of gut hormones in the regulation of energy homeostasis. In particular, the discovery that the gut hormone peptide YY 3-36 ...
Scientists at Seoul National University, Medical Department detail research in insulin resistance.
Mar 02, 2009 ... "Intrahepatic or intramuscular lipid (IHL/IML)content has been reported to be correlated with insulin resistance. Visceral fat has also been shown to be associated with insulin resistance," scientists writing in the journal Obesity report (see also Insulin Resistance). "Thus, we ...
Studies from R. Khan and co-authors have provided new information about kidney failure.
Mar 02, 2009 ... According to recent research published in the Journal of Hospital Medicine, "A 50-year-old male with anuria, creatinine of 5.5 and potassium of 6.5 was referred to our hospital for hemodialysis. Before hemodialysis could be initiated, his blood pressure dropped and liver function tests ...
Reports outline life sciences study findings from L. Shen and colleagues.(Report)
Mar 02, 2009 ... "Resistant starch (RS) is fermentable dietary fiber. Inclusion of RS in the diet causes decreased body fat accumulation and altered gut hormone profile," scientists in the United States report (see also Life Sciences). "This study investigates the effect of feeding RS on the ...