Recently added articles from The Journal of Nutrition:
Physical Activity Prevents Augmented Body Fat Accretion in Moderately Iron-Deficient Rats1,2
Jul 01, 2008; McClung, James P; Andersen, Nancy E; Tarr, Tyson N; Stahl, Chad H; Young, Andrew J ... Abstract Recent studies describe an association between poor iron status and obesity in humans, although the mechanism explaining this relationship is unclear. The present study aimed to determine the effect of moderate iron deficiency and physical activity (PA) on body composition in an ...
Metabolomics Provide New Insight on the Metabolism of Dietary Phytochemicals in Rats1,2
Jul 01, 2008; Fardet, Anthony; Llorach, Rafael; Orsoni, Alexina; Martin, Jean-François; Pujos-Guillot, Estelle; Lapierre, Catherine; Scalbert, Augustin ... Abstract Foods of plant origin contain a large number of phytochemicals that may positively affect health. Phytochemicals are largely excreted in urine as metabolites that are formed in host tissues or by the microbiota and constitute a great proportion of the urinary metabolome. The ...
Luminal Threonine Concentration Acutely Affects Intestinal Mucosal Protein and Mucin Synthesis in Piglets1-3
Jul 01, 2008; Nichols, Natalie L; Bertolo, Robert F ... Abstract Intestinal mucin synthesis is sensitive to dietary threonine supply, which suggests that the gut's requirement for threonine may comprise a significant proportion of the whole body requirement. We used a continuously perfused gut loop model and intraluminal flooding dose ...
A Meal Enriched with Soy Isoflavones Increases Nitric Oxide-Mediated Vasodilation in Healthy Postmenopausal Women1,2
Jul 01, 2008; Hall, Wendy L; Formanuik, Nichola L; Harnpanich, Duangporn; Cheung, Monique; Talbot, Duncan; Chowienczyk, Philip J; Sanders, Thomas A B ... Abstract Evidence from infusion studies suggests that soy isoflavones influence nitric oxide-dependent vasorelaxation. It is uncertain whether orally consumed isoflavones have similar effects. Healthy postmenopausal women (n = 22) consumed 2 low-fat test meals in random order 1 wk apart, ...
Enterolactone Induces Heme Oxygenase-1 Expression through Nuclear Factor-E2-Related Factor 2 Activation in Endothelial Cells1,2
Jul 01, 2008; Kivelä, Annukka M; Kansanen, Emilia; Jyrkkänen, Henna-Kaisa; Nurmi, Tarja; Ylä-Herttuala, Seppo; Levonen, Anna-Liisa ... Abstract Enterolactone is a lignan formed by enterobacteria from precursors in plant foods. Due to its phenolic structure, it can act as an antioxidant, e.g. via direct scavenging of hydroxyl radical. Moreover, many, but not all, phenolic compounds can have indirect antioxidative effects ...
Cardiac Cytochrome c Oxidase Activity and Contents of Subunits 1 and 4 Are Altered in Offspring by Low Prenatal Copper Intake by Rat Dams1,2
Jul 01, 2008; Johnson, W Thomas; Anderson, Cindy M ... Abstract It has been reported previously that the offspring of rat dams consuming low dietary copper (Cu) during pregnancy and lactation experience a deficiency in cardiac cytochrome c oxidase (CCO) characterized by reduced catalytic activity and mitochondrial and nuclear subunit content ...
The Citrus Flavonoids Hesperetin and Nobiletin Differentially Regulate Low Density Lipoprotein Receptor Gene Transcription in HepG2 Liver Cells1-3
Jul 01, 2008; Morin, Brian; Nichols, LaNita A; Zalasky, Katherine M; Davis, J Wade; Manthey, John A; Holland, Lené J ... Abstract Reduction of plasma cholesterol by citrus flavonoids is associated with effects on specific liver functions related to lipid handling. In previous in vivo studies, polymethoxylated flavones (PMF) reduced plasma cholesterol levels at lower doses than required for flavanones. To ...
Dietary Arginine Supplementation Affects Microvascular Development in the Small Intestine of Early-Weaned Pigs1-3
Jul 01, 2008; Zhan, Zhenfeng; Ou, Deyuan; Piao, Xiangshu; Kim, Sung Woo; Liu, Yanhong; Wang, Junjun ... Abstract This study was conducted to evaluate the effects of dietary arginine levels on microvascular development of the small intestine in early-weaned pigs. Twenty-four crossbred pigs (5.0 ± 0.3 kg body weight) were individually housed and randomly allotted to 1 of 3 diets supplemented ...
Acute Administration of Cefepime Lowers L-Carnitine Concentrations in Early Lactation Stage Rat Milk1-3
Jul 01, 2008; Ling, Binbing; Alcorn, Jane ... Abstract Our study investigated the potential for important in vivo drug-nutrient transport interactions at the lactating mammary gland using the L-carnitine transporter substrates, cefepime and L-carnitine, as proof-of-concept. On d 4 (n = 6/treatment) and d 10 (n = 6/treatment) of ...
Retinoids Modulate Expression of the Endocytic Partners Megalin, Cubilin, and Disabled-2 and Uptake of Vitamin D-Binding Protein in Human Mammary Cells1,2
Jul 01, 2008; Chlon, Timothy M; Taffany, David A; Welsh, JoEllen; Rowling, Matthew J ... Abstract The major circulating form of vitamin D, 25-hydroxycholecalciferol (25D3), circulates bound to vitamin D-binding protein (DBP). Prior to activation to 1,25-dihydroxycholecalciferol in the kidney, the 25D3-DBP complex is internalized via receptormediated endocytosis, which is ...
Eubacterium limosum Activates Isoxanthohumol from Hops (Humulus lupulus L.) into the Potent Phytoestrogen 8-Prenylnaringenin In Vitro and in Rat Intestine1-3
Jul 01, 2008; Possemiers, Sam; Rabot, Sylvie; Espín, Juan Carlos; Bruneau, Aurélia; Philippe, Catherine; González-Sarrías, Antonio; Heyerick, Arne; Tomás-Barberán, Francisco A; De Keukeleire, Denis; Verstraete, Willy ... Abstract Recently, it was shown that the exposure to the potent hop phytoestrogen 8-prenylnaringenin (8-PN) depends on intestinal bacterial activation of isoxanthohumol (IX), but this occurs in only one-third of tested individuals. As the butyrate-producing Eubacterium limosum can ...
High Dose Lycopene Supplementation Increases Hepatic Cytochrome P4502E1 Protein and Inflammation in Alcohol-Fed Rats1,2
Jul 01, 2008; Veeramachaneni, Sudipta; Ausman, Lynne M; Choi, Sang Woon; Russell, Robert M; Wang, Xiang-Dong ... Abstract Recent in vitro evidence suggests that the antioxidant lycopene can prevent alcohol-induced oxidative stress and inflammation. However, knowledge of possible interactions in vivo between escalating doses of lycopene and chronic alcohol ingestion are lacking. In this study, we ...
Dietary Glutamine Supplementation Increases the Activity of Peritoneal Macrophages and Hemopoiesis in Early-Weaned Mice Inoculated with Mycobacterium bovis Bacillus Calmette-Guérin1,2
Jul 01, 2008; Rogero, Marcelo Macedo; Tirapegui, Julio; Vinolo, Marco Aurélio Ramirez; Borges, Maria Carolina; de Castro, Inar Alves; de Oliveira Pires, Ivanir Santana; Borelli, Primavera ... Abstract Infants who are breast-fed have been shown to have a lower incidence of certain infectious diseases compared with formula-fed infants. Glutamine is one of the most abundant amino acids found in maternal rnilk and it is essential for the function of immune system cells such as ...
Low Estimates of Dietary Acid Load Are Positively Associated with Bone Ultrasound in Women Older Than 75 Years of Age with a Lifetime Fracture1,2
Jul 01, 2008; Wynn, Emma; Lanham-New, Susan A; Krieg, Marc-Antoine; Whittamore, David R; Burckhardt, Peter ... Abstract Dietary acid load from Western diets may be a risk factor for osteoporosis. It can be estimated by net endogenous acid production (NEAP). No data currently exists for NEAP estimates and bone indices in the very elderly (i.e. ≥75 y). The aim of this study was to determine ...
ERRATUM
Jul 01, 2008; Anonymous ... Lichtenstein AH, Rasmussen H, Yu WW, Epstein SR, Russell RM (2008). Modified MyPyramid for older ...
ERRATUM
Jul 01, 2008; Anonymous ... Kirkpatrick SI, Tarasuk V (2008). Food insecurity is associated with nutrient inadequacies among Canadian adults and adolescents. J Nutr. 138:604-612. Table 3 on page 607 contains errors for the means for energy (EI:EER) and protein (g/kg). These errors do not affect any of the ...
Announcements
Jul 01, 2008; Anonymous ... July 20-25, 2008 FASEB Summer Conference: Molecular Mechanisms Involved in the Nutrient Control of Cellular Function and Metabolism. Carefree, AZ. For more information: visit https://secure.faseb.org/faseb/ meetings/Summrconf/Programs/11715.pdf. August 10-15, ...
Soy Isoflavone Intake Is Not Associated with the Development of Cedar Pollinosis in Adults1,2
Jul 01, 2008; Nagata, Chisato; Nakamura, Kozue; Fujii, Kaori; Kawachi, Toshiaki; Takatsuka, Naoyoshi; Oba, Shino; Shimizu, Hiroyuki ... Abstract Although soy isoflavone has been suggested to have both immune-enhancing and immune-suppressive effects, the effects of soy isoflavone intake on allergic disorders are unclear. A cross-sectional study indicated that a high intake of soy isoflavone is associated with a decreased ...
The Bioavailability of Vitamin D from Fortified Cheeses and Supplements Is Equivalent in Adults1,2
Jul 01, 2008; Wagner, Dennis; Sidhom, Gloria; Whiting, Susan J; Rousseau, Dérick; Vieth, Reinhold ... Abstract There is a need to increase the options for vitamin D fortification. We have developed a method to fortify hard cheese with vitamin D. Our aim was to characterize the bioavailability of vitamin D from fortified cheeses. Eighty adults were randomized to weekly servings of ...
Soy Phytochemicals Decrease Nonsmall Cell Lung Cancer Growth In Female Athymic Mice1-3
Jul 01, 2008; Gallo, Daniela; Zannoni, Gian Franco; De Stefano, Ilaria; Mosca, Marco; Ferlini, Cristiano; Mantuano, Elisabetta; Scambia, Giovanni ... Abstract This study investigated the effects of a phytoestrogen-containing standardized soy extract (SSE) on the growth of nonsmall cell lung cancer (NSCLC; A549) xenografts in female athymic mice. Tumor-bearing mice received either sterile water or SSE [50 or 100 mg/(kg*d), per os], 5 ...