The Journal of Nutrition back issues from March 2001:
Function of vitamin A in vertebrate embryonic development
Mar 01, 2001; ... Function of Vitamin A in Vertebrate Embryonic Development 1,2 ABSTRACT Advances in molecular biology and retinoic acid receptor research have significantly contributed to the understanding of the role of vitamin A during vertebrate development. Examination of the function of this ...
Glucagon-like peptide 2: A nutrient-responsive gut growth factor
Mar 01, 2001; ... Glucagon-Like Peptide 2: A Nutrient-Responsive Gut Growth Factor1,2,3 ABSTRACT Glucagon-like peptide 2 (GLP-2) is a 33-amino acid peptide derived from the tissue-specific, post-translational processing of the proglucagon gene expressed in the intestinal enteroendocrine L-cell. The ...
Franklin Church Bing (1902-1988)
Mar 01, 2001; ... Franklin Bing, described variously by his colleagues as public servant, scientist, scholar, historian and warm, ever-helpful friend, was a pioneer in the use of sound scientific information for the formation of public policy related to food and nutrition. He was a member of the American ...
Phosphatidylcholine inhibits and lysophosphatidylcholine enhances the lymphatic absorption of (alpha)-tocopherol in adult rats
Mar 01, 2001; ... Phosphatidylcholine Inhibits and Lysophosphatidylcholine Enhances the Lymphatic Absorption of a-Tocopherol in Adult Rats 1 ABSTRACT This study was conducted to compare the effects of enterally infused phosphatidylcholine (PC) and lysophosphatidylcholine (lysoPC) on the lymphatic ...
Soybean isoflavones dose-dependently reduce bone turnover but do not reverse established osteopenia in adult ovariectomized rats
Mar 01, 2001; ... Soybean Isoflavones Dose-Dependently Reduce Bone Turnover but Do Not Reverse Established Osteopenia in Adult Ovariectomized Rats1 ABSTRACT We assessed the dose-dependent effects of daily soybean isoflavone (IF) consumption in reversing bone loss in adult ovariectomized rats. On d 0, ...
Folate status during pregnancy in women is improved by long-term high vegetable intake compared with the average western diet
Mar 01, 2001; ... ABSTRACT The effect of increasing dietary folate on folate status during pregnancy is controversial. The aim of this study was to compare folate intake and folate status during pregnancy of women with high long-term vegetable intake and those eating an average Western diet. In a prospective ...
Wheat bran and soy protein feeding do not alter urinary excretion of the isoflavan equol in premenopausal women
Mar 01, 2001; ... Wheat Bran and Soy Protein Feeding Do Not Alter Urinary Excretion of the Isoflavan Equol in Premenopausal Women1 ABSTRACT The capacity to convert the soy isoflavone daidzein to equol in vivo is presumably determined by an individual's intestinal microfloral populations; however, diet ...
Red wine is a poor source of bioavailable flavonols in men
Mar 01, 2001; ... Red Wine Is a Poor Source of Bioavailable Flavonols in Men 1 (Manuscript received 9 August 2000. Initial review completed 13 September 2000. Revision accepted 11 December 2000.) ABSTRACT Red wine is a source of polyphenolic antioxidants, of which flavonols such as quercetin are ...
An assessment of various household food security measures in Hawaii has implications for National Food Security Research and Monitoring
Mar 01, 2001; ... An Assessment of Various Household Food Security Measures in Hawaii Has Implications for National Food Security Research and Monitoring'2 ABSTRACT The Core Food Security Module (CFSM), the national food security monitoring tool, requires three affirmative responses to categorize ...
Dietary intakes and socioeconomic factors are associated with the hemoglobin concentration of Bangladeshi women
Mar 01, 2001; ... Dietary Intakes and Socioeconomic Factors Are Associated with the Hemoglobin Concentration of Bangladeshi Women1 ABSTRACT Iron deficiency anemia affects a large number of women in developing countries, especially during child-bearing years. The hemoglobin concentration is useful for ...
Understanding needs is important for assessing the impact of food assistance program participation on nutritional and health status in U.S. elderly persons
Mar 01, 2001; ... ABSTRACT This study aimed to assess the impact of food assistance programs on nutritional and health status of nutritionally needy elderly persons. Two cross-sectional and one longitudinal data sets were used: Third National Health and Nutrition Examination Survey (1988-94), Nutrition Survey of ...
Serum albumin binds (beta-) and (alpha)-monoolein in vitro
Mar 01, 2001; ... Serum Albumin Binds beta- and alpha-Monoolein In Vitro1 ABSTRACT We investigated the interaction of bovine serum albumin (BSA) and monoolein (MO) and estimated the number of BSA binding sites for the alpha- and beta-isomers of MO. The turbidity of increasing concentrations of aqueous ...
Dietary fructooligosaccharides modify intestinal bioavailability of a single dose of genistein and daidzein and affect their urinary excretion and kinetics in blood of rats
Mar 01, 2001; ... ABSTRACT The influence of dietary fructooligosaccharides (FOS) on bioavailability of genistein and daidzein in rats was estimated by measuring their concentrations in plasma collected from three different veins and in urine after a single intragastric administration of isoflavone conjugates ....
L-arabinose feeding prevents increases due to dietary sucrose in lipogenic enzymes and triacylglycerol levels in rats
Mar 01, 2001; ... L-Arabinose Feeding Prevents Increases Due to Dietary Sucrose in Lipogenic Enzymes and Triacylglycerol Levels in Rats' ABSTRACT L-Arabinose is a natural, poorly absorbed pentose that selectively inhibits intestinal sucrase activity. To investigate the effects of L-arabinose feeding on ...
Olive oil prevents the adverse effects of dietary conjugated linoleic acid on chick hatchability and egg quality
Mar 01, 2001; ... Olive Oil Prevents the Adverse Effects of Dietary Conjugated Linoleic Acid on Chick Hatchability and Egg Quality1 ABSTRACT Dietary conjugated linoleic acid (CLA) decreases yolk 18:1(n-9), induces chick embryonic mortality and alters egg quality. A study was conducted to determine ...
Kefir milk enhances intestinal immunity in young but not old rats
Mar 01, 2001; ... Kefir Milk Enhances Intestinal Immunity in Young but Not Old Rats 1 ABSTRACT The adjuvant effect of kefir fermented milk on the mucosal and systemic immune systems was examined in young (6 mo old) and old (26 mo old) rats. Kefir-fed rats consisted of young or old rats consuming ...
A pancreatic extract-enriched diet improves the nutritional status of aged rats
Mar 01, 2001; ... A Pancreatic Extract-Enriched Diet Improves the Nutritional Status of Aged Rats-12 ABSTRACT Correction of the malnourished state, particularly common and severe in elderly people, is often unsuccessful. To improve the efficiency of realimentation, we evaluated the nutritional effect of ...
Energy restriction does not alter bone mineral metabolism or reproductive cycling and hormones in female rhesus monkeys
Mar 01, 2001; ... ABSTRACT Energy restriction (ER) extends the life span and slows aging and age-related diseases in short-lived mammalian species. Although a wide variety of physiological systems have been studied using this paradigm, little is known regarding the effects of ER on skeletal health and ...
Fatty acid composition of adiopse tissue and serum lipids are valid biological markers of dairy fat intake in men
Mar 01, 2001; ... Fatty Acid Composition of Adipose Tissue and Serum Lipids Are Valid Biological Markers Of Dairy Fat Intake in Men1 ABSTRACT The fatty acid intake is in part reflected by the fatty acid composition of adipose tissue and serum lipids. We evaluated whether the proportions of myristic ...
More antioxidants in cocoa
Mar 01, 2001; ... Dear Dr. Rein: Rein and colleagues (1) reported that cocoa might contribute to the plasma total antioxidant capacity because of its high content of flavan-3-ols (epicatechin). The consumption of cocoa by the Dutch population is relatively high compared with that of other groups, and it ...
More antioxidants in cocoa
Mar 01, 2001; ... Dear Dr. Lamuela-Raventos: The letter by Lamuela-Raventos et al. discussed data that suggest quercetin could be contributing to a significant part of the antioxidant activity observed in humans after the consumption of chocolate. We agree that it is a point worth discussing for two ...
Symposium: Leucine as a nutritional signal--introduction
Mar 01, 2001; ... Introduction,1 Although the anabolic effects of amino acids originating from dietary protein on protein synthesis and cell function were first reported over 20 years ago, until recently the molecular basis for many of these observations remained elusive. Now there is convincing evidence ...
Symposium: Leucine as a nutritional signal--regulation of branched-chain (alpah)-keto acid dehydrogenase kinase expression in rat liver
Mar 01, 2001; ... Regulation of Branched-Chain ci-Keto Acid Dehydrogenase Kinase Expression in Rat Liver'2 ABSTRACT Branched-chain amino acids are toxic in excess but have to be conserved for protein synthesis. This is accomplished in large part by control of the activity of the branched-chain a-keto ...
Symposium: Leucine as a nutritional signal--function of leucine in excitatory neurotransmitter metabolism in the central nervous system
Mar 01, 2001; ... Function of Leucine in Excitatory Neurotransmitter Metabolism in the Central Nervous System,1,2 ABSTRACT A novel hypothesis for the role of branched-chain amino acids (BCAA) in regulating levels of the major excitatory neurotransmitter glutamate in the central nervous system is ...
Symposium: Leucine as a nutritional signal--Molecular mechanisms in the brain involved in the anorexia of branched-chain amino acid deficiency
Mar 01, 2001; ... Molecular Mechanisms in the Brain Involved in the Anorexia of BranchedChain Amino Acid Deficiency I,2 ABSTRACT The anterior piriform cortex (APC) of the rat is thought to be the site of indispensable amino acid (IAA) chemosensation in the brain. The branched-chain amino acids, including ...
Symposium: Leucine as a nutritional signal--Signaling pathways involved in translational control of protein synthesis in skeletal muscle by leucine
Mar 01, 2001; ... Signaling Pathways Involved in Translational Control of Protein Synthesis in Skeletal Muscle by Leucine1 ABSTRACT Numerous reports established that in skeletal muscle the indispensable branched-chain amino acid leucine is unique in its ability to initiate signal transduction pathways ...
Symposium: Leucine as a nutritional signal--role of leucine in the regulation of mTOR by amino acids: Revelations from structure-activity studies
Mar 01, 2001; ... Role of Leucine in the Regulation of mTOR by Amino Acids: Revelations from Structure-Activity Studies1,2 ABSTRACT In this study an overview is presented of the mTOR signaling pathway and its regulation by amino acids, particularly L-leucine. Our laboratory is studying amino acid ...
Symposium: Obesity in developing countries: Biological and ecological factors--introduction
Mar 01, 2001; ... Introduction1 ABSTRACT Over the past decade there has been an increasing concern about the impact of chronic, noncommunicable diseases on the health of developing world populations. Traditionally, major causes of illness and death in developing countries have been linked to infectious ...
Symposium: Obesity in developing countries: Biological and ecological factors--The nutrition transition and obesity in the developing world
Mar 01, 2001; ... The Nutrition Transition and Obesity in the Developing World,1 ABSTRACT Changes in diet and activity patterns are fueling the obesity epidemic. These rapid changes in the levels and composition of dietary and activity/inactivity patterns in transitional societies are related to a number ...
Symposium: Obesity in developing countries: Biological and ecological factors--Early nutrition and later adiposity
Mar 01, 2001; ... Early Nutrition and Later Adiposity1 ABSTRACT The objective was to review whether nutrition during pregnancy and the first 3 y of life predisposes individuals to be fatter as adults. The roles of undernutrition, overnutrition and breastfeeding were considered. The evidence that poor ...
Symposium: Obesity in developing countries: Biological and ecological factors--independent effects of income and education on the risk of obesity in the Brazilian adult population
Mar 01, 2001; ... Independent Effects of Income and Education on the Risk of Obesity in the Brazilian Adult Population1 ABSTRACT With a view to assess the independent effects of income and education on the risk of obesity we studied cross-sectional randomly selected samples of the adult population (20 y ...
Symposium: Obesity in developing countries: Biological and ecological factors--diet culture and obesity in Northern Africa
Mar 01, 2001; ... Diet Culture and Obesity in Northern Africa 1 ABSTRACT The etiology of obesity in North Africa is not well understood and few studies shed any light on its development among women. This study compiles what is known about the prevalence of obesity and its determinants in Morocco and ...
Symposium: Obesity in developing countries: Biological and ecological factors--obesity trends in Latin America: Transiting from under- to overweight
Mar 01, 2001; ... Obesity Trends in Latin America: Transiting from Under- to Overweight' ABSTRACT Latin America is undergoing a rapid demographic and nutritional transition. A recent WHO/PAHO survey on obesity in the region revealed an increasing trend in obesity as countries emerge from poverty, ...
Symposium: Calorie restriction: Effects on body composition, insulin signaling and aging--introduction
Mar 01, 2001; ... Introduction,1,2 ABSTRACT At this time of increasing attention to the worldwide problem of obesity and its negative consequences for health and well being, it is timely to present a symposium on the effects of calorie restriction and the potential for calorie restriction mimetic ...
Symposium: Calorie restriction: Effects on body composition, insulin signaling and aging--the role of fat depletion in the biological benefits of caloric restriction
Mar 01, 2001; ... The Role of Fat Depletion in the Biological Benefits of Caloric Restriction'2 ABSTRACT One of the most robust observations in the biology of aging is that caloric restriction (CR) extends life in a variety of species. Although CR results in substantial decrease in fat mass, the role of ...
Symposium: Calorie restriction: Effects on body composition, insulin signaling and aging--in vivo insulin regulation of skeletal muscle glycogen synthase in calorie-restricted...
Mar 01, 2001; ... In Vivo Insulin Regulation of Skeletal Muscle Glyco en Synthase in CalorieRestricted and in Ad Libitum-Fed Rhesus Monkeys ABSTRACT Chronic calorie restriction in primates has been shown to have profound and unexpected effects on basal and on in vivo insulin action on skeletal muscle ...
Symposium: Calorie restriction: Effects on body composition, insulin signaling and aging--calorie restriction in obesity: Prevention of kidney disease in rodents
Mar 01, 2001; ... Calorie Restriction in Obesity: Prevention of Kidney Disease in Rodents'2 ABSTRACT The incidence of end-stage renal disease (ESRD) has risen considerably in the past two decades. This trend is partly due to the alarming rise in the incidence of type 2 diabetes over the same period, ...
Symposium: Calorie restriction: Effects on body composition, insulin signaling and aging--microarray profiling of gene expression in aging and its alteration by caloric...
Mar 01, 2001; ... Microarray Profiling of Gene Expression in Aging and Its Alteration by Caloric Restriction in Mice 12 ABSTRACT An active research area in biological gerontology concerns the mechanisms by which caloric restriction (CR) retards the aging process in laboratory rodents. We used high ...
Symposium: Calorie restriction: Effects on body composition, insulin signaling and aging--characterization of diet-dependent metabolic serotypes: Analytical and biological...
Mar 01, 2001; ... Characterization of Diet-Dependent Metabolic Serotypes: Analytical and Biological Variability Issues in Rats 1'2 ABSTRACT This report, the first in a series on diet-dependent changes in the serum metabolome (metabolic serotype), describes validation of the use of high performance liquid ...
Symposium: Pediatric pulmonary insufficiency: Nutritional strategies for prevention and treatment--introduction
Mar 01, 2001; ... Introduction,1 In the pediatric population, disorders of chronic pulmonary insufficiency include bronchopulmonary dysplasia in prematurely born infants, and asthma, cystic fibrosis and congenital heart and lung disorders in both infants and children. Although first-line therapy usually ...
Symposium: Pediatric pulmonary insufficiency: Nutritional strategies for prevention and treatment--energy expenditure in infants with pulmonary insufficiency: Is there evidence...
Mar 01, 2001; ... Energy Expenditure in Infants with Pulmonary Insufficiency: Is There Evidence for Increased Energy Needs?1,2 ABSTRACT The observed growth failure in infants with pulmonary insufficiency is postulated to be a consequence of elevated rates of energy expenditure. Assessment of energy ...
Symposium: Pediatric pulmonary insufficiency: Nutritional strategies for prevention and treatment--chronic pulmonary insufficiency in children and its effects on growth development
Mar 01, 2001; ... Chronic Pulmonary Insufficiency in Children and Its Effects on Growth and Development1,2 ABSTRACT Conditions leading to chronic pulmonary insufficiency can affect infants and children. These can lead to growth failure and delayed development. Among the most common and severe of these ...
Symposium: Pediatric pulmonary insufficiency: Nutritional strategies for prevention and treatment--special nutritional needs of infants for prevention of and recovery from...
Mar 01, 2001; ... Special Nutritional Needs of Infants for Prevention of and Recovery from Bronchopulmonary Dysplasia I2 ABSTRACT Extremely low birth weight infants who develop severe respiratory disease may have special nutrient requirements imposed by a combination of enhanced utilization of nutrients ...
Symposium: Pediatric pulmonary insufficiency: Nutritional strategies for prevention and treatment--is there a role for antioxidant therapy in bronchopulmonary dysplasia?
Mar 01, 2001; ... Is There a Role for Antioxidant Therapy in Bronchopulmonary Dysplasia?1 ABSTRACT Bronchopulmonary dysplasia (BPD) is a chronic lung disease first described in 1967 as a complication of therapy for premature infants with hyaline membrane disease, and treatment with high concentrations of ...
Chronic but not acute energy restriction increases intestinal nutrient transport in mice
Mar 01, 2001; ... Chronic but Not Acute Energy Restriction Increases Intestinal Nutrient Transport in Mice1 ABSTRACT Chronic energy restriction (ER) dramatically enhances intestinal absorption of nutrients by aged mice. Do adaptations in nutrient absorption develop only after extended ER or immediately ...
Introduction
Mar 01, 2001; ... Garlic has been of interest to physicians and the general public since antiquity. Bulbs of garlic have been found in excavations of ancient tombs in Egypt, Greece, China and Japan. There is even evidence that garlic was an officially sanctioned so-called "performance enhancing" agent at the ...
Historical perspective on the use of garlic
Mar 01, 2001; ... Historical Perspective on the Use of Garlic 1,2 ABSTRACT The objective of this review is to examine briefly the medical uses of garlic throughout the ages and the role that it was considered to play in prevention and treatment of disease. Interest in the potential benefits of garlic has ...
Intake of garlic and its bioactive components
Mar 01, 2001; ... Intake of Garlic and Its Bioactive Components1 ABSTRACT The health benefits of garlic likely arise from a wide variety of components, possibly working synergistically. The complex chemistry of garlic makes it plausible that variations in processing can yield quite different ...
How to distinguish garlic from the other Allium vegetables
Mar 01, 2001; ... How to Distinguish Garlic from the Other Allium Vegetables' ABSTRACT The establishment of international monographs for herbs is in progress. Here, we propose both a marker compound and a method for its analysis for the identification of garlic bulbs and their products. The constituents ...
Determination of allicin, S-allylcysteine and volatile metabolites of garlic in breath, plasma or simulated gastric fluids
Mar 01, 2001; ... Determination of Allicin, S-Allylcysteine and Volatile Metabolites of Garlic in Breath, Plasma or Simulated Gastric Fluids 1,2 ABSTRACT Various components of garlic and aged garlic extract, including allicin, S-allylcysteine (SAC) and volatile metabolites of allicin were determined in ...
N(alpha)-(1-deoxy-D-fructos-1-yl)-L-arginine, an antioxidant compound identified in aged garlic extract
Mar 01, 2001; ... Nalpha-(1-Deoxy-D-fructos-1-yl)-L-Arginine, an Antioxidant Compound Identified in Aged Garlic Extract1 ABSTRACT Aged garlic extract (AGE) has been shown to have antioxidant activity. The organosulfur compounds, S-allyl-L-cysteine and S-allylmercapto-L-Cysteine, are responsible, at least ...
Historical perspective on garlic and cardiovascular disease
Mar 01, 2001; ... Historical Perspective on Garlic and Cardiovascular Disease1 ABSTRACT Cardiovascular disease is a complex and multifactorial disease characterized by such factors as high cholesterol, hypertension, reduced fibrinolysis, increase in blood-clotting time and increased platelet aggregation ....
Aged garlic extract, a modulator of cardiovascular risk factors: A dose-finding study on the effects of AGE on platelet functions
Mar 01, 2001; ... Aged Garlic Extract, a Modulator of Cardiovascular Risk Factors: A Dose-Finding Study on the Effects of AGE on Platelet Functions1 ABSTRACT Aged garlic extract (AGE) has been shown previously to have moderate cholesterol-lowering and blood pressure-reducing effects. We have now ...
Suppression of LDL oxidation by garlic
Mar 01, 2001; ... Suppression of LDL Oxidation by Garlic1,2 ABSTRACT It has been known for several decades that hypercholesterolemia is a major risk factor for atherosclerosis and that lowering of cholesterol can significantly reduce risk for cardiovascular diseases. More recently, oxidation of LDL has ...
Cholesterol-lowering effect of garlic extracts and organosulfur compounds: Human and animal studies
Mar 01, 2001; ... Cholesterol-Lowering Effect of Garlic Extracts and Organosulfur Compounds: Human and Animal Studies' ABSTRACT The medicinal use of garlic dates back thousands of years, but there was little scientific support of its therapeutic and pharmacologic properties until recently. In the past ...
Study of garlic extracts and fractions on cholesterol plasma levels and vascular reactivity in cholesterol-fed rats
Mar 01, 2001; ... Study of Garlic Extracts and Fractions on Cholesterol Plasma Levels and Vascular Reactivity in Cholesterol-Fed Rats1 ABSTRACT Garlic is known for its pharmacologic and nutritional properties. In previous studies, garlic elicited a reduction in plasma levels of lipids by inhibiting ...
Saponins in garlic as modifiers of the risk of cardiovascular disease
Mar 01, 2001; ... Saponins in Garlic as Modifiers of the Risk of Cardiovascular Disease1 Recent Advances on the Nutritional Effects Associated with the Use of Garlic as a Supplement ABSTRACT Most chemical and biological studies about garlic have been conducted using organosulfur compounds ....
Molecular basis by which garlic suppresses atherosclerosis
Mar 01, 2001; ... Molecular Basis by Which Garlic Suppresses Atherosclerosis1 ABSTRACT The aim of this study was to determine the mechanism by which the aged garlic extract "Kyolic" has a protective effect against atherosclerosis. Plasma cholesterol of rabbits fed a 1 % cholesterol-enriched diet for 6 wk ...
Antioxidant health effects of aged garlic extract
Mar 01, 2001; ... Antioxidant Health Effects of Aged Garlic Extract' ABSTRACT Oxidative modification of DNA, proteins and lipids by reactive oxygen species (ROS) plays a role in aging and disease, including cardiovascular, neurodegenerative and inflammatory diseases and cancer. Extracts of fresh garlic ...
The effects of aged garlic extract on lipid peroxidation and the deformability of erythrocytes
Mar 01, 2001; ... The Effects of Aged Garlic Extract on Lipid Peroxidation and the Deformability of Erythrocytes,1 ABSTRACT The effects of aged garlic extract (AGE) on lipid peroxidative damage and the deformability of erythrocytes were evaluated in rats. The deformability of erythrocytes was measured ...
Garlic compounds minimize intracellular oxidative stress and inhibit nuclear factor-(k)B activation
Mar 01, 2001; ... Garlic Compounds Minimize Intracellular Oxidative Stress and Inhibit Nuclear Factor-kB Activation1,2 ABSTRACT Oxidative modification of LDL has been recognized as playing an important role in the initiation and progression of atherosclerosis. In this study, we determined the effects of ...
A historical perspective on garlic and cancer
Mar 01, 2001; ... A Historical Perspective on Garlic and Cancer' ABSTRACT Epidemiological and laboratory studies provide insight into the anticarcinogenic potential of garlic and its constituent compounds. Both water- and lipid-soluble allyl sulfur compounds are effective in blocking a myriad of ...
Garlic and cancer: A critical review of the epidemiologic literature
Mar 01, 2001; ... Garlic and Cancer: A Critical Review of the Epidemiologic Literature1 ABSTRACT Animal and in vitro studies provide evidence of an anticarcinogenic effect of active ingredients in garlic. This review of the epidemiologic literature on garlic consumption addresses cancers of the stomach, ...
Mechanisms of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and related compounds from garlic
Mar 01, 2001; ... Mechanisms of Inhibition of Chemical Toxicity and Carcinogenesis by Diallyl Sulfide (DAS) and Related Compounds from Garlic1,2 ABSTRACT Diallyl sulfide (DAS) is a flavor compound derived from garlic and is sequentially converted to diallyl sulfoxide (DASO) and diallyl sulfone (DASO^sub ...
Impact of garlic organosulfides on p21(H-ras) processing
Mar 01, 2001; ... Impact of Garlic Organosulfides on p21H-ras Processing'2 ABSTRACT This study describes the novel anticarcinogenic activity of diallyl disulfide, a naturally occurring organosulfide from garlic. Oral administration of diallyl disulfide resulted in a dose-dependent and significant ...