The Journal of Nutrition back issues from April 2008:
Serum Amyloid A Protein Regulates the Expression of Porcine Genes Related to Lipid Metabolism1-3
Apr 01, 2008; ... Abstract Serum amyloid A protein (SAA) is an apolipoprotein that can replace apolipoprotein A1 (apoA1) as the major apolipoprotein of HDL. Porcine hepatic SAA mRNA is increased by dietary docosahexaenoic acid (DHA) treatment. The purpose of this study was to investigate the role of SAA ...
Biotin Deficiency Affects the Proliferation of Human Embryonic Palatal Mesenchymal Cells in Culture1,2
Apr 01, 2008; ... Abstract It has recently been demonstrated that pregnancy in women may cause mild biotin deficiency without any clinical signs. However, the teratogenicity of biotin deficiency in humans has not been well investigated. On the other hand, our previous studies have shown that maternal ...
ATP7A Transgenic and Nontransgenic Mice Are Resistant to High Copper Exposure1-3
Apr 01, 2008; ... Abstract The protein affected in Menkes disease, ATP7A, is a copper (Cu)-transporting P-type ATPase that plays an important role in Cu homeostasis, but the full extent of this role has not been defined at a systemic level. Transgenic mice that overexpress the human ATP7A from the chicken ...
Zinc Deficiency Alters DNA Damage Response Genes in Normal Human Prostate Epithelial Cells1-3
Apr 01, 2008; ... Abstract Zinc is an essential trace element for human health and is a critical component of many proteins and transcription factors involved in DNA damage response and repair. The prostate is known to accumulate high levels of zinc, but levels are markedly decreased with cancer ...
Caco-2 Intestinal Epithelial Cells Absorb Soybean Ferritin by µ^sub 2^ (AP2)-Dependent Endocytosis1,2
Apr 01, 2008; ... Abstract Iron deficiency, a condition currently affecting ~3 billion people, persists in the 21st century despite half a millennium of medical treatment. Soybean ferritin (SBFn), a large, stable protein nanocage around a mineral with hundreds of iron and oxygen atoms, is a source of ...
Energy Expenditure, Satiety, and Plasma Ghrelin, Glucagon-Like Peptide 1, and Peptide Tyrosine-Tyrosine Concentrations following a Single High-Protein Lunch1,2
Apr 01, 2008; ... Abstract High-protein (HP) foods are more satiating and have a higher thermogenic effect than normal protein foods over the short-term as well as the long-term. We hypothesized that acute effects of higher protein intake on satiety may be related to acute metabolic and hormonal ...
Chronic Dietary Intake of Plant-Derived Anthocyanins Protects the Rat Heart against Ischemia-Reperfusion Injury1-3
Apr 01, 2008; ... Abstract Consumption of flavonoid-rich foods and beverages is thought to reduce the risk of cardiovascular diseases. Whereas the biological activities of flavonoids have been characterized in vitro, there are no clear experimental data demonstrating that chronic dietary intake and ...
Long-Term Intake of a High-Protein Diet with or without Potassium Citrate Modulates Acid-Base Metabolism, but Not Bone Status, in Male Rats1
Apr 01, 2008; ... Abstract High dietary protein intake generates endogenous acid production, which may adversely affect bone health. Alkaline potassium citrate (Kcit) may contribute to the neutralization of the protein-induced metabolic acidosis. We investigated the impact of 2 levels of protein intake ...
Including Indigestible Carbohydrates in the Evening Meal of Healthy Subjects Improves Glucose Tolerance, Lowers Inflammatory Markers, and Increases Satiety after a Subsequent Standardized Breakfast1,2
Apr 01, 2008; ... Abstract Low-glycemic index (GI) foods and foods rich in whole grain are associated with reduced risk of type 2 diabetes and cardiovascular disease. We studied the effect of cereal-based bread evening meals (50 g available starch), varying in GI and content of indigestible carbohydrates, ...
Daily Consumption of a Dark Chocolate Containing Flavanols and Added Sterol Esters Affects Cardiovascular Risk Factors in a Normotensive Population with Elevated Cholesterol1,2
Apr 01, 2008; ... Abstract Previous studies with plant sterols (PS) and cocoa flavanols (CF) provide support for their dietary use in maintaining cardiovascular health. This double-blind, placebo-controlled, cross-over study evaluated the efficacy of daily consumption of a cocoa flavanol-containing dark ...
Postweaning Dietary Folate Deficiency Provided through Childhood to Puberty Permanently Increases Genomic DNA Methylation in Adult Rat Liver1-3
Apr 01, 2008; ... Abstract Folate plays an important role in the pathogenesis of several chronic diseases by its potential ability to modulate DNA methylation. We hypothesized that the postweaning period might be a highly susceptible period to dietary folate intervention for DNA methylation patterning. We ...
Serum C-Reactive Protein Concentrations Are Inversely Associated with Dietary Flavonoid Intake in U.S. Adults1
Apr 01, 2008; ... Abstract Serum C-reactive protein (CRP) is a biomarker for chronic inflammation and a sensitive risk factor for cardiovascular diseases. Though CRP has been reported to be related to food intake, there is no documentation of a direct association with flavonoid intake. We aimed to test ...
Bolus Oral Glutamine Protects Rats against CPT-11-Induced Diarrhea and Differentially Activates Cytoprotective Mechanisms in Host Intestine but Not Tumor1,2
Apr 01, 2008; ... Abstract Dietary glutamine has been suggested to preserve structural and functional integrity of the gut and high dose bolus glutamine has been hypothesized to protect against potentially fatal endotoxic shock, hyperthermic stress, and side effects of chemotherapy. In this study, we ...
The Oportunidades Program Increases the Linear Growth of Children Enrolled at Young Ages in Urban Mexico1,2
Apr 01, 2008; ... Abstract The goal of this study was to evaluate the impact of Mexico's conditional cash transfer program, Oportunidades, on the growth of children <24 mo of age living in urban areas. Beneficiary families received cash transfers, a fortified food (targeted to pregnant and lactating ...
Regular Users of Supermarkets in Greater Tunis Have a Slightly Improved Diet Quality1-3
Apr 01, 2008; ... Abstract Despite the recent and rapid expansion of supermarkets in developing countries, their association with diet quality has been hardly studied. The study took place in Tunisia, where incidences of obesity and nutrition-related diseases are rising. The target population was ...
Maternal Night Blindness during Pregnancy Is Associated with Low Birthweight, Morbidity, and Poor Growth in South India1,2
Apr 01, 2008; ... Abstract Maternal night blindness is common during pregnancy in many developing countries. Previous studies have demonstrated important consequences of maternal night blindness during pregnancy on the health of the mother and newborn infant. We compared birthweight, 6-mo infant ...
Intake of Vegetables, Legumes, and Fruit, and Risk for All-Cause, Cardiovascular, and Cancer Mortality in a European Diabetic Population1,2
Apr 01, 2008; ... Abstract We examined the associations of intake of vegetables, legumes and fruit with all-cause and cause-specific mortality in a population with prevalent diabetes in Europe. A cohort of 10,449 participants with self-reported diabetes within the European Prospective Investigation into ...
Fortifying Brown Bread with Sodium Iron EDTA, Ferrous Fumarate, or Electrolytic Iron Does Not Affect Iron Status in South African Schoolchildren1,2
Apr 01, 2008; ... Abstract The choice of iron fortificant usually represents a balance between bioavailability of the compound and its tendency to cause organoleptic problems. The aim of this study was to evaluate the efficacy of sodium iron EDTA (NaFeEDTA) and ferrous fumarate at levels compatible with ...
Maternal Symptoms of Stress, Depression, and Anxiety Are Related to Nonresponsive Feeding Styles in a Statewide Sample of WIC Participants1,2
Apr 01, 2008; ... Abstract Parenting, including nonresponsive feeding styles, has been related to under- or overweight among young children. The relationship between maternal mental health and feeding styles has not been examined. We hypothesized that mothers who report more symptoms of stress, ...
A Macadamia Nut-Rich Diet Reduces Total and LDL-Cholesterol in Mildly Hypercholesterolemic Men and Women1,2
Apr 01, 2008; ... Abstract Epidemiologic studies and clinical trials have demonstrated that the unique fatty acid profile of nuts beneficially affects serum lipids/lipoproteins, reducing cardiovascular disease (CVD) risk. Nuts are low in SFA and high in PUFA and monounsaturated fatty acids (MUFA) ....
Diminished Primary CD8 T Cell Response to Viral Infection during Protein Energy Malnutrition in Mice Is Due to Changes in Microenvironment and Low Numbers of Viral-Specific CD8 T Cell Precursors1-3
Apr 01, 2008; ... Abstract Protein energy malnutrition (PEM) increases the incidence and severity of infection, causing morbidity and mortality in malnourished populations. Viral-specific cells are an important component of protective immunity. We hypothesized that reduction in the expansion of ...
Docosahexaenoic Acid-Enriched Fish Oil Consumption Modulates Immunoglobulin Responses to and Clearance of Enteric Reovirus Infection in Mice1,2
Apr 01, 2008; ... Abstract We hypothesized that consumption of the (n-3) PUFA, docosahexaenoic acid (DHA), modulates the mucosal immune response to enteric infection with respiratory enteric orphan virus (reovirus), a model intestinal pathogen. Mice were fed either AIN-93G control diet, containing 10 g/kg ...
Antioxidant Supplementation Increases Skin Cancer Risk, or, Why Zinc Should Not Be Considered an Antioxidant/Reply to Dr. Schrauzer
Apr 01, 2008; ... Dear Editor, The increased skin cancer risk among the female participants of the SU.VXMAX (Supplementation en Vitamines et Minéraux Antioxidants) trial (1) indeed suggests, as the authors point out, that ".. .dietary supplementation with vitamins and trace element antioxidants may not ...
Announcements
Apr 01, 2008; ... April 4, 2008 A Symposium on Women in Science, Medicine, and Engineering. Boston, MA. For more information: visit http://www.tufts.edu./central/research/ WISME. April 5-8, 2008 Experimental Biology 2008. San Diego, California. For ...
Ruminal Infusions of Cobalt-EDTA Reduce Mammary [Delta]9-Desaturase Index and Alter Milk Fatty Acid Composition in Lactating Cows1-3
Apr 01, 2008; ... Abstract Ruminal administration of a triple indigestible marker system comprised of cobalt EDTA (CoEDTA), ytterbium acetate (YbAc), and chromium-mordanted straw (CrS) decreases product:substrate ratios for Δ9-desaturase in bovine milk fat. This experiment was designed to identify ...
Luminal Starch Substrate "Brake" on Maltase-Glucoamylase Activity Is Located within the Glucoamylase Subunit1-3
Apr 01, 2008; ... Abstract The detailed mechanistic aspects for the final starch digestion process leading to effective α-glucogenesis by the 2 mucosal α-glucosidases, human sucrase-isomaltase complex (SI) and human maltase-glucoamylase (MGAM), are poorly understood. This is due to the ...
Strain Differences in Mice Highlight the Role of DNA Damage in Neoplasia Induced by Low Dietary Folate1,2
Apr 01, 2008; ... Abstract In earlier work, we showed that low dietary folate induced intestinal tumors in BALB/c mice. In this study, our goal was to examine the effect of the same diets on a strain that is more resistant to tumorigenesis (C57BI/6). We also questioned whether supplementation of the ...