Women's Health Weekly back issues from January 2004:
Second opinion from major center leads to better detection, treatment changes.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Women with breast cancer who seek a second opinion on their mammograms from experienced specialists at a major cancer center frequently get a new plan for their care, a new study shows. Some even learn that they have cancer in more ...
Synthetic progestin damages, estrogen protects blood vessels in animal model.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Synthetic progestins may be the major cause of harmful side effects reported with hormone replacement therapy. University of South Florida researchers used a novel imaging technique to show that progestins caused toxicity while natural ...
New human breast and ovarian cancer gene described.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- A new human breast and ovarian cancer gene has been described by a team of researchers in the U.K. and Canada. The gene, called EMSY, also characterizes a subset of breast cancer with poorer survival, which makes it a potentially ...
Low iron levels associate with hair loss in women.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Low iron levels associate with hair loss in women. "Alopecia in women is a common problem, and conflicting observational data have failed to determine whether an association exists between alopecia and iron deficiency in women. We ...
Finger length predicts sperm retrieval and pregnancy success after IVF/ICSI.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Finger length predicts sperm retrieval and pregnancy success after IVF/ICSI. According to published research from England, "the differentiation of the urogenital system and the appendicular skeleton in vertebrates is under the control of ...
Couples may be receiving too much information about their fetuses.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Couples may be receiving too much information about their fetuses. According to a study from England, "the amount of information available to couples about the health of their fetus is increasing. An important question in prenatal ...
Arbitrator: City council can't exclude voluntary procedure from health benefits.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Cincinnati, Ohio, must restore voluntary abortion coverage to city employee health benefits and reimburse any employee who has had an abortion since city council banned the coverage, an arbitrator ruled. The union, which represents about ...
TRAF6 has many essential functions spanning immune, bone, and nerve functions.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- TRAF6 has many essential functions spanning immune, bone, endocrine, and nerve functions. "Tumor necrosis factor (TNF) receptor associated factor 6 (TRAF6) is a crucial signaling molecule regulating a diverse array of physiological ...
Antiemetic improves control of chemotherapy-induced nausea, vomiting.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- A post-hoc analysis of two Phase III trials for Emend (aprepitant) showed that treatment with Emend in combination with a 5-HT3 receptor antagonist and a corticosteroid ("regimen with Emend ") significantly improved emetic control in both women and ...
Hypoxic myocytes produce growth factor that stimulates COX-2 production.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Hypoxic myocytes produce growth factor that stimulates COX-2 production. According to published research from the United States, "there is increasing evidence that cyclooxygenase (COX)-2 possess both angiogenic and cardioprotective ...
Global Precision Medical licenses Thermal Ablation Technology.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Global Precision Medical, Inc., (GBPMF) announced that on December 2, 2003, it entered into an agreement to acquire an exclusive worldwide license from MDMI Technologies, Inc., (MDMI), of Richmond, British Columbia, to apply their proprietary ...
A decreased level of ERbeta mRNA may be associated with breast tumorigenesis.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- A decreased level of ERbeta mRNA may be associated with breast tumorigenesis and DNA methylation is an important mechanism for ERbeta gene silencing in breast cancer, researchers say. "Two novel estrogen receptor beta (ERbeta) mRNA ...
Advexin vaccine therapy to begin phase I/II.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Introgen Therapeutics, Inc., (INGN) announced that its vaccine therapy, INGN 225, will be evaluated at two U.S. cancer centers in a phase I/II study to treat patients with advanced breast cancer. The trial will be conducted by Drs ....
Analysis shows Faslodex effective in treating metastatic breast cancer.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Results from two pivotal phase III trials looking at overall survival demonstrate that Faslodex (fulvestrant) Injection is an effective alternative to Arimidex (anastrozole) Tablets in the treatment of postmenopausal women with advanced breast ...
Aromatase inhibitors' signal disruption mechanism differs from Tamoxifen.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Aromatase inhibitors for breast cancer alter estrogen-receptor signaling differently than tamoxifen, researchers say. According to a study from England, "Endocrine therapy with tamoxifen has been the mainstay of treatment for ...
Breast cancer assay quantifies likelihood of breast cancer recurrence in study.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- The National Surgical Adjuvant Breast and Bowel Project (NSABP) and Genomic Health, Inc., announced that their large, prospective trial met its defined endpoints and validated that Genomic Health's unique breast cancer assay can accurately and ...
Breast cancer risk from antibiotics may be due to altered immunity, microflora.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Breast cancer may develop with sustained antibiotic use due to influence on immunity as well as reduced intestinal microflora carcinogen processing. According to recent research published in the journal Cancer Causes & Control, "the ...
Breast imaging workstation designed to support advanced CAD applications.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- R2 Technology, Inc., a computer-aided detection (CAD) company, and MeVis BreastCare (MBC), GmbH, Co., KG, of Bremen, Germany, a developer of softcopy reading software for breast cancer diagnosis, announced a license agreement whereby the MBC ...
Breast tissue differentiation using arterial spin tagging may detect cancer.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Breast tissue differentiation using arterial spin tagging (AST) can potentially detect cancer, researchers report. "An AST pulse sequence has been developed to measure T-1 and relative blood perfusion. This full sequence is composed of ...
Cancer survivors speak out on treatment options.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- A large percentage of women with breast cancer would choose to undergo chemotherapy, even if it only reduced the risk of breast cancer mortality by 1%, states a survey presented at the 26th annual San Antonio Breast Cancer Symposium. ...
Combination genomics technique greatly improves breast carcinoma detection.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Combining cytogenetic and DNA flow cytometric analyses of breast carcinomas significantly improves the information obtained by either technique used alone, researchers say. "The cytogenetic and DNA flow cytometric findings in 242 breast ...
Combination therapy shows improved survival in breast cancer patients.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Genentech, Inc., (DNA) and Roche announced updated results from a clinical study evaluating Herceptin (Trastuzumab) in combination with Taxotere (docetaxel) as a first-line treatment for HER2 (human epidermal growth factor receptor-2)-positive ...
Combining various MRI techniques may help improve disease detection.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Researchers at Johns Hopkins say that combining various types of magnetic resonance imaging (MRI) techniques more accurately sorts cancers from benign masses in breast tissues than any single imaging techniques. They reported their ...
Company presents data for the en-bloc breast biopsy system at RSNA.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Neothermia Corp., an emerging company focused on the development and marketing of minimally invasive systems for the diagnosis of cancer, announced the first clinical presentation of data for its en-bloc breast biopsy system was made at the 89th ...
Docetaxel-based regimen improves survival and disease-free survival, data show.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- A docetaxel (Taxotere)-based regimen reduced the relative risk of death in women with early stage breast cancer by 30% and lowered the relative risk of the cancer returning by 28% when compared to a standard adjuvant (post-surgery) regimen after ...
Drug-induced apoptosis mechanism via DR-dependent pathway not fully understood.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Apoptosis in drug-resistant cells is induced via DR-independent pathways mediated by mitochondrial dysfunction, researchers report. According to recent research from Japan, "Apoptosis is a crucial event for anticancer drug efficacy. ...
Expression of transglutaminases displayed in human breast cancer.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Breast cancer displays an aberrant expression of transglutaminases (TGase), wherein the levels of TGases-2, 3, and 7 are related to node involvement and patient outcome, researchers say. According to a study from Wales, "Implicated in ...
FDA approves computer-aided detection for digital mammography.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Fischer Imaging Corporation (FIMG) and R2 Technology, Inc., announced that approval has been granted by the U.S. Food and Drug Administration (FDA) for the use of R2's proprietary mammography CAD technology with Fischer's SenoScan TrueView Digital ...
FDA grants fast-track status for drug in certain patients.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Data from an early phase, multi-center clinical trial suggest that GW572016, a reversible inhibitor of two growth factor receptors involved in the proliferation and survival of many solid tumors, in a once-daily oral dose has clinical and ...
First computer-aided detection on PACS demonstrated at meeting.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- R2 Technology, Inc., announced the industry's first computer-aided detection (CAD) on PACS (picture archiving and communications system) workstations, demonstrated at the 89th Scientific Assembly and Annual Meeting of the Radiological Society of ...
Freezing technique kills majority of small malignant tumors.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- A technique already in use to freeze and kill benign breast masses also appears to kill small malignant breast tumors, new research from a clinical trial at the University of Michigan Comprehensive Cancer Centers shows. And while the ...
Gefitinib demonstrates early promise in advanced breast cancer.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Delegates at the 2003 San Antonio, Texas, Breast Cancer Symposium had an early glimpse of the therapeutic potential of the anticancer agent gefitinib (IRESSA, ZD1839) in the treatment of patients with advanced breast cancer. In a phase ...
Genes upregulated by hypoxia are strategic targets for cancer therapy.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Genes upregulated by hypoxia are strategic targets for cancer therapy. According to recent research published in the journal Biomedicine & Pharmacotherapy, "hypoxia is a stress that causes alterations in signal transduction and gene ...
Herstatin inhibits heregulin-mediated breast cancer cell growth.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Herstatin inhibits heregulin-mediated breast cancer cell growth and overcomes tamoxifen resistance in breast cancer cells that overexpress HER-2, researchers say. "Ligands of the ErbB family of receptors and estrogens control the ...
High-dose pre-SCT vinorelbine-paclitaxel regimen safe and effective.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- A high-dose VNB-PTX regimen is safe and effective for breast cancer patients prior to stem-cell transplantation. In a recent study, scientists in Italy evaluated "the safety, activity and peripheral blood progenitor cell-mobilizing ...
NDA completed for treatment of breast cancer with brain metastases.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Allos Therapeutics, Inc., (ALTH) announced that it has submitted to the U.S. Food and Drug Administration (FDA) the last component of its new drug application (NDA) for approval to market RSR13 (efaproxiral) as an adjunct to whole brain radiation ...
New antibody shows promise as agent for radioimmunotherapy of breast cancer.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Immunomedics, Inc., (IMMU) announced results from recent studies of the company's proprietary, humanized antibody, hRS7 (IMMU-112), which demonstrated that when the compound is labeled with iodine-131 using a new, residualizing method patented by ...
New data underlines Modrenal's genetic mechanism of action in breast cancer.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Bioenvision, Inc., (BIV) has presented new data underlining the ability of its lead breast cancer treatment, Modrenal (trilostane), to suppress the activity of estrogen at two groups of genes involved in breast cancer growth. The ...
New drugs tested for effectiveness against advanced cases of disease.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- An experimental chemotherapy drug called Abraxane was more effective in treating advanced cases of breast cancer and carried fewer side effects than its widely used cousin Taxol, according to a study presented at the 26th Annual San Antonio Breast ...
New studies launched with Modrenal.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Bioenvision, Inc., (BIV) announced its intention to conduct new studies in the U.K. in premenopausal, preoperative, and postmenopausal women for its lead breast cancer treatment Modrenal (trilostane). The announcement was made at the ...
Performance audit praises state's oversight of mammography facilities.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Pennsylvania women can be assured that the Commonwealth is inspecting its mammography facilities regularly to verify that they comply with stringent federal quality standards and safety requirements, according to a special performance audit ...
Physicians play key role in breast and cervical cancer screening compliance.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Researchers find that contact with a physician is most effective for promoting breast and cervical screening compliance. "The objective of this study was to examine mammography and cervical cancer screening rates among women aged 50 to ...
Positive survival, quality of life data presented on RSR13 phase III study.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Allos Therapeutics, Inc., (ALTH) announced the presentation of positive findings from its phase III clinical trial of the investigational radiation sensitizer RSR13 (efaproxiral). The results demonstrate a significant survival benefit ...
Postoperative pain from breast cancer surgery decreased without narcotics.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- I-Flow Corporation (IFLO) announced that results of a study of post-surgical pain relief after breast cancer surgery showed that the use of ON-Q Post Operative Pain Relief System following surgery for removal of axillary lymph nodes in patients ...
Review concludes Pennsylvania mammography facilities are inspected properly.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Problems turned up in 28% of Pennsylvania's inspections of certified mammography facilities, according to a report issued on December 4, 2003, by the state auditor general's office that praised how the inspections are conducted. "Most ...
Study evaluates recurrence in those switched from adjuvant tamoxifen to Arimidex.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Study results were presented that evaluated breast cancer recurrence rates in postmenopausal women who had been treated for 2-3 years with adjuvant tamoxifen and then switched to Arimidex (anastrozole) Tablets. These patients were ...
Study: Shows rhIGFBP-3 enhances sensitivity to Herceptin.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Insmed, Inc., (INSM) reported on data from recent studies of the company's proprietary anticancer compound, recombinant human insulin-like growth factor binding protein-3 (rhIGFBP-3). These studies conducted in the laboratory of Dr ....
Supraclavicular lymph node irradiation can reduce thyroid gland size.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Routine en face treatment of the supraclavicular lymph nodes, using the Hockey Stick method, should be reconsidered, researchers say. According to recent research published in the Yonsei Medical Journal, "To identify the effect of ...
Taxotere compared with Taxol in metastatic breast cancer clinical trial.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- In a clinical trial, women treated with Taxotere (docetaxel) Injection Concentrate had a statistically significant improvement in overall survival and time to disease progression compared with those who were treated with Taxol (paclitaxel) for ...
Taxotere increases 5-year breast cancer survival rate in study.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Taxotere (docetaxel) administered as neo-adjuvant (pre-surgery) chemotherapy has been shown to significantly increase the 5-year survival rates of women with large or locally advanced breast cancer when compared with standard neo-adjuvant ...
Scalpel, scissor cause less damage, better results than electrocautery during BCT.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Scalpel plus scissor in breast conserving surgery cause less tissue damage and have better cosmetic results at the 3-year follow-up, researchers say. According to a study from Japan, "Breast conserving therapy (BCT) was originally ...
Gel-filled breast implants approved as class III medical devices in the E.U.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Inamed Corp. (IMDC), a global healthcare company, announced the single lumen models of its silicone gel-filled breast implants have been certified as satisfying the European Union's (E.U.) safety and efficacy requirements for the most stringent ...
Study: HPV test is more effective than Pap smear for cervical cancer screening.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- A new study concludes that in women 30 and older, the HPV (human papillomavirus) DNA test is more effective than the Pap smear alone in identifying women with cervical cancer or its precursors. Investigators say the results of the study ...
Company demonstrates that CTLM detects tumor angiogenesis.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Imaging Diagnostic Systems, Inc., (IMDS) has confirmed that their Computed Tomographic Laser Breast Imaging System (CTLM) can depict angiogenesis associated with tumors. Dr. Eric Milne, professor emeritus of radiology and medicine, UC at ...
Type 1 diabetes associated with increased risk of some cancers.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Certain forms of cancer occur more often in patients with type 1 diabetes compared with the general population in the corresponding sex and age groups. This has been shown in a new Swedish study from Karolinska Institute. The study is ...
Cancer therapeutic candidate licensed to Myriad Genetics.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Maxim Pharmaceuticals (MAXM) announced the exclusive license of its MX90745 series of apoptosis-inducing compounds for the treatment of cancer to Myriad Genetics, Inc. Compounds in the MX90745 series, specifically the current lead ...
Experts dispute link between abortion and breast cancer.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Abortion politics led Minnesota's Health Department to publish unreliable information about a link between abortions and breast cancer, state health workers wrote in e-mails obtained by the Star Tribune of Minneapolis. Government e-mails ...
Genomics-derived (Lp-PLA2) inhibitor to advance to phase III trials.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Human Genome Sciences, Inc., (HGSI) confirmed that its partner, GlaxoSmithKline, presented phase II clinical trial results and discussed its development plan for 480848, a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, at ...
Hypertension is not the cause of increased CD risk during hormone replacement therapy.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Hypertension is not likely to underlie the heightened risk of heart disease associated with hormone replacement therapy. "In recent studies, it has been found that postmenopausal hormonal therapy is associated with an increased incidence ...
GLUT1 protein expression is an indicator of hyperplasia grade cervical cancer.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- GLUT1 protein overexpression is an indicator of hyperplasia, transformation stages, and cervical cancer. "We studied whether induction of glucose transporters (GLUTs) 1 to 4 correlates with human papillomavirus (HPV)-dependent malignant ...
Seungnoidan improves neurological signals in rodents without ovaries.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Seungnoidan improves neurological signals in rodents without ovaries. According to research from South Korea, "this study investigated the effects of Seungnoidan (SND), which has been widely used as a remedy for cerebroneuronal diseases ...
Cyclic changes experienced by women on oral contraception are significant.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Cyclic changes experienced by women on oral contraception are significant. "Despite the widespread use of oral contraceptives (OC) there is no consensus regarding their effect on menstrual cycle experiences. This study examines the ...
Young women in Greece have deficient knowledge about birth control methods.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Young women in Greece have deficient knowledge about birth control methods. "The aims of this study were to investigate the knowledge, attitudes and behavior of female high school and university students concerning contraception. The ...
Outpatient procedure shrinks benign breast lumps.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Breast cryotherapy is a safe, effective, and nearly painless office-based procedure that significantly reduces benign breast lumps without damaging breast structure, according to a study presented at the 89th Scientific Assembly and Annual Meeting ...
Beers criteria for medications to avoid in the elderly are updated.
Jan 01, 2004 ... 2004 JAN 1 - (NewsRx.com & NewsRx.net) -- Forty-eight medications or classes of medications to avoid in adults age 65 or older have been identified by a expert panel in the U.S. charged with updating widely used criteria for potentially harmful medications in older adults. ...