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Article: drug resistance
- Article from:
- The Columbia Encyclopedia, Sixth Edition
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Copyright informationThe Columbia Encyclopedia, Sixth Edition. Copyright 2008 Columbia University Press. (Hide copyright information)
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drug resistance condition in which infecting
bacteria
can resist the destructive effects of drugs such as
antibiotics
and
sulfa drugs
. Drug resistance has become a serious public health problem, since many disease-causing bacteria are no longer susceptible to previously effective drug therapies. For nearly 50 years after the first antibiotic, penicillin, became available in the 1940s, people took antibiotics' effectiveness against bacterial infections for granted. By the 1960s some doctors were predicting the end of infectious diseases. By the 1990s, however, a "post-antibiotic era," characterized by the proliferation of untreatable bacterial strains, was considered inevitable, ...
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