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Article: Chromosomal aberrations contribute to morphological changes in leiomyosarcomas.
- Article from:
- Cancer Gene Therapy Week
- Article date:
- April 28, 2003
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2003 APR 28 - (NewsRx.com & NewsRx.net) -- Chromosomal aberrations contribute to morphological changes in leiomyosarcomas.
"To identify a characteristic cytogenetic aberration and cytogenetic-morphological correlation in soft-tissue leiomyosarcomas, a karyotypic and clinicopathological analysis of 15 cases of leiomyosarcoma was performed," scientists in Japan report.
"The histological type was classical in nine cases, pleomorphic in three cases and myxoid in three cases. The histological grade was 1 in three cases, 2 in 10 cases and 3 in two cases. Nine of 15 tumors displayed an abnormal karyotype, whereas the other six tumors displayed a normal ...