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Article: Ebola and lassa viruses target dendritic cells and prevent cytokine release.
- Article from:
- Medical Letter on the CDC & FDA
- Article date:
- May 4, 2003
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2003 MAY 4 - (NewsRx.com & NewsRx.net) -- Ebola and lassa viruses target dendritic cells and prevent them from releasing cytokines
According to a study from the United States, "Acute infection of humans with Ebola and Lassa viruses, two principal etiologic agents of hemorrhagic fevers, often results in a paradoxical pattern of immune responses: early infection, characterized by an outpouring of inflammatory mediators such as TNF-alpha, IL-1-beta, and IL-6, vs late stage infections, which are associated with poor immune responses. The mechanisms underlying these diverse outcomes are poorly understood."
"In particular, the role played by cells of the ...