Article: Insulin resistance provides link between cigarette smoking and heart disease.

2003 MAY 11 - (NewsRx.com & NewsRx.net) -- Researchers have proposed that insulin resistance and compensatory hyperinsulinemia are key links between cigarette smoking and cardiovascular disease.

"Hyperinsulinemia, dyslipidemia, and endothelial dysfunction are characteristic findings in insulin-resistant individuals, and all of these abnormalities have been identified as increasing cardiovascular disease (CVD) risk. Smokers tend to be relatively insulin resistant, hyperinsulinemic, and dyslipidemic, with evidence of endothelial dysfunction, as compared with nonsmokers, and recent epidemiologic data have suggested that CVD in smokers is primarily seen in those ...

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