Article: Study Shows Nighttime Dosing of Biovail's Cardizem LA Lowers Blood Pressure and Other Risks More Than Nighttime Dosing of Altace.

Business Editors/Health/Medical Writers

NEW YORK--(BUSINESS WIRE)--May 16, 2003

New Graded-Release Diltiazem Formulation Outperforms "ACE" from HOPE

Trial

In one of the first head-to-head trials to compare the advantages of two blood pressure treatments administered at night, Biovail Corporation's (NYSE, TSX: BVF) Cardizem(R) LA outperformed Altace(R), the nation's top selling branded ACE inhibitor, on trial endpoints including reductions in early-morning and 24-hour blood pressure, heart rate and rate-pressure product, a strong correlate of myocardial oxygen consumption.

The benefits of Cardizem(R) LA, a new graded-release ...

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