Article: Phase III Trial of Avastin Plus Chemotherapy Markedly Extends Survival of Metastatic Colorectal Cancer Patients.

Business Editors/Health/Medical Writers

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SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--May 19, 2003

First Positive Phase III Results With an Anti-Angiogenic Therapy

for Cancer; Data to be Submitted to Upcoming ASCO Meeting

Genentech, Inc. (NYSE:DNA) today announced that a Phase III study of Avastin(TM) (bevacizumab, rhuMAb-VEGF) plus chemotherapy in previously-untreated metastatic colorectal cancer patients met its primary endpoint of improving overall survival. The magnitude of the benefit observed far exceeded what the study was designed to demonstrate. The trial also met the secondary endpoints of progression-free ...

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