Article: Gene screen nabs new genes.

2003 MAY 30 - (NewsRx.com & NewsRx.net) -- Howard Hughes Medical Institute researchers have combed through a catalog of all known tyrosine kinase enzymes to identify new gene mutations that occur in a significant fraction of colon cancers.

Researchers have known for years that abnormal activity of tyrosine kinases can hasten the development of certain forms of cancer. In this first-of-a-kind survey, researchers used a forward-looking approach to screen the genes that produce tyrosine kinases - reasoning that somewhere in this genomic landscape they might encounter novel mutations that spur colon cancer and other types of cancer.

The researchers - ...

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