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Article: Endogenous opioid beta-endorphin plays role in energy homeostasis.
- Article from:
- Obesity, Fitness & Wellness Week
- Article date:
- June 14, 2003
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2003 JUN 14 - (NewsRx.com & NewsRx.net) -- Endogenous opioid beta-endorphin appears to play a role in energy homeostasis.
"Proopiomelanocortin (POMC) neurons in the hypothalamus are direct targets of the adipostatic hormone leptin and contribute to energy homeostasis by integrating peripheral and central information. The melanocortin and beta-endorphin neuropeptides are processed from POMC and putatively coreleased at axon terminals. Melanocortins have been shown by a combination of pharmacological and genetic methods to have inhibitory effects on appetite and body weight," scientists writing in the journal Endocrinology report.
"In contrast, ...