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Article: Grapefruit juice gives drug an added punch. (can cause side effects if taken with antihypertensive drug felodipine)
- Article from:
- Science News
- Article date:
- February 9, 1991
- Author:
CopyrightCOPYRIGHT 1991 Science Service, Inc. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)
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Grapefruit juice gives drug an added punch
Tangy grapefruit juice may pack an unwanted punch. Canadian researchers have discovered that an experimental antihypertensive drug, if taken with grapefruit juice, can cause a rash of side effects, including rapid heart rate, facial flushing and dizziness.
"This is the first example of a pharmacokinetic interaction between a citrus juice and a drug," study coauthor David G. Bailey told SCIENCE NEWS. The results underscore the potential for hazardous effects when people consume certain foods with specific drugs, he says.
The new finding has its roots in an earlier study at the University of Western ...