Article: Barrett's esophagus. (Esophagoscopy Clinic).(Brief Article)

A 48-year-old white man with a history of laryngopharyngeal reflux underwent 24-hour double-probe ambulatory pH testing. He denied any heartburn. This study demonstrated abnormal degrees of reflux in both his esophagus and pharynx. Transnasal esophagoscopy (TNE) detected an erythematous area in the lower third of his esophagus (figure). Biopsies were diagnostic for Barrett's esophagus.

Barrett's esophagus is a premalignant condition caused by chronic reflux. During the repetitive process of inflammation and repair, a metaplastic process occurs, and abnormal columnar epithelium that is normally seen in the stomach replaces the injured esophageal epithelium. ...

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