Article: Birth defects among low birth weight infants - metropolitan Atlanta, 1978-1988.

Approximately 3%-4% of newborn infants have a major birth defect diagnosed during their first year of life (1). Because many infants with birth defects are born prematurely and/or have intrauterine growth retardation (2-5), the rate of birth defects is expected to vary by birth weight. This report summarizes a population-based study of the relation between birth defect rates and the birth weight of infants born in metropolitan Atlanta from 1978 through 1988. Data from the population-based Metropolitan Atlanta Congenital Defects Program (MACDP) for 1978-1988 were used to study the rate of birth defects in infants in five birth-weight categories ([less than or equal to] 1499 ...

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