Article: Mouse and human endocrine gland-derived VEGF function the same in vascular beds.

2003 JUL 25 - (NewsRx.com & NewsRx.net) -- Mouse and human endocrine gland-derived VEGF function the same in vascular beds.

"We recently described human endocrine gland-derived vascular endothelial growth factor (EG-VEGF) as an endothelial cell mitogen with a novel selective activity and an expression pattern essentially limited to steroidogenic glands. Herein we present the identification and characterization of the mouse ortholog. The mouse cDNA and predicted amino acid sequences are, respectively, 86% and 88% identical with the human," according to a study from the United States.

"Surprisingly, the mouse EG-VEGF transcript is predominantly expressed ...

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