Article: The pineal gland and the immune system may talk via melatonin and cytokines.

2003 JUL 21 - (NewsRx.com & NewsRx.net) -- Melatonin is part of the bidirectional communication between pineal gland and the immune system's activated cell products.

According to recent research from Poland, "The pineal gland is a vertebrate neuroendocrine organ converting environmental photoperiodic information into a biochemical message (melatonin) that subsequently regulates the activity of numerous target tissues after its release into the bloodstream. A phylogenetically conserved feature is increased melatonin synthesis during darkness, even though there are differences between mammals and birds in the regulation of rhythmic pinealocyte function.

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